14-Day Italy Self-Drive Road Trip With Itinerary from Florence traveling south to Pisa, Rome, Salerno, Naples, and Perugia

Day 2 of your road trip will take you to the best attractions Florence has to offer. Cherish the 1 night you have left in Florence by discovering the best things there are to see and do in the city.

Enjoy the perfect balance of relaxation and exploration in Florence today. One of the most spectacular attractions included on the itinerary is Piazza Della Signoria. This grand public square will help you start your sightseeing on top. Then, take a leisurely stroll to Uffizi Gallery and learn what makes this historic art gallery unique.

Throughout the day, make sure to take breaks to appreciate the surroundings. Next up, visit the iconic Ponte Vecchio. After exploring the historical landmark, head to Pitti Palace. This popular palace is a highlight in Florence. Lastly, don’t forget to check out the locally renowned The Boboli Gardens. Enjoy exploring this incredible botanical garden at your own pace.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

Bring home unique finds from Florence's bustling shopping hub, Via de' Tornabuoni. Enjoy a leisurely exploration of unique boutiques and high-end stores where locals shop. Don’t forget to browse souvenirs and local specialties that make perfect gifts for your loved ones. Beyond shopping, Via de' Tornabuoni offers plenty of options, including primary services, unique landmarks, and community events.

Indulge in a memorable dining experience at one of Florence's most popular restaurants, and connect with friendly locals for an authentic adventure.

Experience a taste of local culinary excellence while in Florence by securing a table at Enoteca Pinchiorri. An esteemed 3-star Michelin restaurant, it features an exceptional italian contemporary menu. For an alternative taste experience, visit Santa Elisabetta, famous for its scrumptious creative and mediterranean dishes. This 2-star Michelin venue consistently impresses guests, making it a standout addition to your holiday plans. Looking for another choice? Discover Gucci Osteria da Massimo Bottura, a local favorite celebrated for its exquisite italian contemporary and international cuisine in Florence. Located in the heart of the city, this 1-star Michelin restaurant is an ideal pick for italian contemporary and international cuisine lovers seeking top-notch culinary experiences.

After your meal, keep the night alive at a bar like Bar 50 Rosso, known for its lively atmosphere. Bitter Bar is another top recommendation that provides the perfect setting with well-crafted drinks and a welcoming ambiance. Similarly, Archea Brewery offers an excellent atmosphere for those looking to amp up the evening.

Get a good night's sleep and look forward to another great day on the road in Italy!

Embark on another extraordinary experience on day 3 of your road trip in Italy. Today, you will make 1 stop and experience some of the highlights of Florence. At the end of the day, you will enjoy the comforts of a top-rated hotel in Pisa, which will be your home away from home for 1 night.

Today’s well-planned self-sightseeing route offers several family-friendly attractions, photo-friendly spots, and history-rich sites. Whether you decide to explore Florence on foot, use public transport, or join a guided tour, there are a few attractions you don’t want to miss. Basilica Of Santa Croce In Florence is the first of them. Spend some time admiring this culturally significant church before continuing your journey. Galleria Dell'accademia is your next stop. This locally renowned art gallery is one of the best-rated sights in Florence.

Consider grabbing some lunch or a light snack to keep your energy going. Beyond the above-mentioned attractions, today is also the perfect time to visit Cathedral Of Santa Maria Del Fiore. This enchanting church is a sight to behold. To round off your sightseeing experience, visit Basilica Di Santa Maria Novella, Firenze (fi).

At the end of the day, you will drive to Pisa, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

After a day of adventure, treat yourself to an exquisite dinner at one of Pisa's best restaurants.

Make sure to reserve a table at Anima di Grano Pizzeria Napoletana Pisa Italy, an iconic dining spot in Pisa. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of il Mercante, a popular restaurant in Pisa. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of La Ghiotteria, a hidden gem nestled in Pisa. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

After enjoying a fulfilling meal, continue your evening at Jeffer Cocktails & Friends, ideal for those looking to unwind with a drink in a comfortable setting. Alternatively, Le Parisien Wine Bar offers a welcoming atmosphere for easing into the nightlife. Similarly, Las Volta Cocktailbar provides an excellent environment for a relaxed and enjoyable evening.

Raise your glass to another unforgettable day in Italy!

Experience an unparalleled adventure on day 4 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 1 vibrant destinations - Pisa. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Rome. You will spend 5 nights here for some well-deserved relaxation.

Get ready for a day filled with family-friendly attractions, breathtaking views, and picturesque spots in the charming city of Pisa. Your adventure starts at Knights' Square, an up-and-coming local hot spot. Another notable attraction to explore is Leaning Tower Of Pisa. This iconic monument is known for its culturally significant appeal.

After soaking in the highlights of these sights, take some time to wander Pisa's streets and immerse yourself in the local atmosphere. When you're ready to continue your sightseeing adventure, head to Piazza Del Duomo, Pisa. This historic public square offers a fascinating experience that many visitors find memorable. Pisa Cathedral is also worth visiting.

When you’re done exploring for the day, you’ll drive to your hotel in Rome. Check in and spend some time relaxing before you head out to tour the city.

As you explore more of Rome, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Prepare for an extraordinary culinary adventure in Rome by booking a table at La Pergola, a 3-star Michelin restaurant that boasts an exceptional mediterranean and contemporary menu. For a different flavor experience, head to Il Pagliaccio, renowned for its delectable creative and innovative dishes. This 2-star Michelin restaurant consistently wows guests, making it a memorable stop during your holiday. Looking for another option? Visit Enoteca La Torre, a local gem known for its delightful mediterranean and creative cuisine in Rome. Nestled in the city's heart, this 2-star Michelin restaurant is a perfect choice for discerning restaurant-goers seeking a new experience.

Round off your dining experience by visiting La Botticella Of Poggi Giovanni, a prime location for a drink. Alternatively, explore the distinctive characteristics of Almalu Trastevere, a bar catering to every mood and preference. Bar Viminale Di Pepi Maurilio likewise offers a unique atmosphere, perfect for a memorable night out.

Relax and reminisce about your day in Italy and look forward to more memorable moments to come!

Greet day 5 of your road trip in Italy with a smile and start your day with a hearty breakfast. You will return to Rome for your remaining 4 nights in the city later today, but first, it’s time for some exploring! On the agenda for this day, you’ll find only the best things to see and do in Vatican City.

Bring your curiosity for today’s adventure around Vatican City. Some of the city’s most loved attractions await.

Vatican City’s wonders await as you prepare for another journey on the road, leaving the breathtaking surroundings of Rome behind. This drive usually takes around 11 min. Vatican City welcomes you with a multitude of unique vacation experiences.

Next, visit Saint Peter's Square, a popular square that offers a unique experience. Be sure to also explore Vatican Museums, a nearby art museum, which is highly recommended by other travelers.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Rome.

After a day of adventure, treat yourself to an exquisite dinner at one of Rome's best restaurants.

Treat yourself to a wonderful meal at RomAntica, a top-rated dining spot in Rome. If you're in the mood for something new, try Coso Ristorante, another premier location with a delectable menu. You might also want to book a table at DEROMA - Farine Romane. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Rome.

Unwind after your meal by stepping into Sant' Eustachio Caffè. This venue is celebrated for its extensive drink selections and cozy vibes. Alternatively, Yellowsquare Rome offers a dynamic and energetic atmosphere for a glass or two. Don’t overlook Caffè Portofino, another top-rated bar in the area.

Raise your glass and celebrate another amazing day of your road trip in Italy!

Day 6 offers a multitude of experiences. You will stay in Rome for 3 nights more, offering you enough time to explore at a relaxed pace.

A blend of fun adventures, romantic experiences, and breathtaking views await you in Rome on today’s itinerary. First up is the widely recognized public square, Spanish Steps. It's a standout spot that offers a memorable visit. Afterward, continue to Piazza Di Spagna. A visit to this public square is an enriching experience for all.

As you explore Rome’s charming streets, take in the lively atmosphere and get to know the character of the city. Next, make your way to Trevi Fountain. This timeless monument is an essential stop that should not be missed. Following that, head to Pantheon, another must-visit site that will enhance your experience. Lastly, visit Largo Di Torre Argentina and learn why this archeological site is renowned as one of the city's most locally renowned attractions.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Rome. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Enjoy a delicious meal at Hotel de Russie, a top-rated dining destination in Rome. If you're in the mood to try something new, consider La Taverna Italiana, another top spot with a mouthwatering menu. You might also want to secure a reservation at The Parrot Bar. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Rome this evening.

Keep the excitement of the evening going by visiting a bar or two. The Apartment Bar Roma is an excellent place to start. You could also check out Hotel Hassler Roma, offering a different kind of charm.

Raise your glass to another unforgettable day in Italy!

On day 7 of your road trip, you will have an entire day to explore Rome. You’ll stay in Rome for 2 nights and discover all the best things to see and do in the area.

Prepare for a day full of fun adventures, breathtaking views, and picturesque spots. When you’re ready, kick off your sightseeing adventure at Altare Della Patria. This notable monument is a must-visit for anyone seeking a unique vacation experience. Another sight you shouldn’t miss is Capitoline Hill, one of the city’s most promising highlights.

Next, check out Roman Forum, one of the most iconic places to see in Rome. This archeological site is a favorite among locals and travelers alike. Enjoy some downtime and refreshments before continuing to your next stop, Colosseum. Wander around and soak in the awe-inspiring atmosphere this archeological site offers. Finally, take the path to the locally renowned Circus Maximus, the last of our attraction recommendations for today.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

After a day of adventure, treat yourself to an exquisite dinner at one of Rome's best restaurants.

Savor the flavors at Sofitel Roma Villa Borghese, a top pick for dinner tonight. Alternatively, Centro beckons with its unique menu offerings. Also, consider Ristorante Tema. With its consistent customer satisfaction, it’s an excellent option for dining in Rome tonight.

Savor another day of unforgettable experiences in Italy!

Day 8 of your road trip across Italy promises a magnificent time exploring Rome. You have 1 night left in Rome. Take the opportunity to experience more of the best attractions and activities in the city.

Savor the day by visiting some of the best places to see in Rome, including a park, a public square, and a castle. Start your adventure at Villa Borghese. This top-rated park is a must-visit for travelers looking for a unique holiday experience. Make your way to Piazza Del Popolo located in Rome for an enchanting atmosphere.

Next, immerse yourself in the setting of Castel Sant'angelo. Its culturally significant features will captivate you. After the castle, continue your tour of the city with a visit to Piazza Navona. This public square has an enchanting appeal. For a change of pace, head to Campo De' Fiori. As one of the most widely recognized attractions in Rome, this public square is an excellent place to end your self-guided tour.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

As dinnertime approaches, it's time to head out for a bite to eat in Rome. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Have a fantastic dining experience at Ristorante Va. Do. , a highly recommended choice for tonight's dinner. If you're looking to mix things up, Giulia Restaurant offers an enticing alternative with its varied menu. Additionally, L'Archeologia is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Rome.

Take some time to reflect on your day and savor another beautiful night in Italy.

On day 9 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 2 destinations, Paestum and Salerno. When you’re not sightseeing, take time to relax at your selected hotel in Salerno, where you’ll be staying for 1 night.

Paestum’s wonders await as you prepare for another journey on the road, leaving the breathtaking surroundings of Rome behind. This drive usually takes around 3 hours 27 min. Paestum welcomes you with a multitude of unique vacation experiences.

Savor the rest of your day by heading to Second Temple Of Hera, an increasingly popular archeological site that draws visitors from near and far. When you're done, continue on to Archaeological Park Of Paestum, where you can soak in the historic surroundings.

After soaking in Paestum’s unique atmosphere, jump into the car with a full heart and drive in the direction of your next destination: Salerno. Expect your car journey to take a minimum of 50 min. When you arrive in Salerno, it's time to take a break from the road.

Take your self-guided tour to Cathedral Of Santa Maria Degli Angeli, San Matteo And San Gregorio Vii, an underrated church that everyone visiting Salerno should see. Enjoy sightseeing at your own pace and allow yourself time to explore the beautiful surroundings.

After soaking up all the sights of today's itinerary, you'll be ready to hit the road in the direction of your accommodation in Salerno. Salerno offers plenty of top-rated hotels and other places to stay on any travel budget. Take some time to relax before you head out to explore.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Salerno. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Experience a harmony of flavors at Re Maurì in Salerno by securing a reservation in advance. Known for its 1-star Michelin status, Re Maurì offers a delightful variety of dishes highlighting its delicious creative menu. If you're looking to mix things up, L'Unico Drink & Food Salerno offers an enticing alternative with its varied menu.

After savoring a delicious meal, step into the vibrant nightlife at Hilton Bar E Gastronomia, where the evening is just getting started. In the same way, The Black Monday Speakeasy Tbm offers a unique charm perfect for experiencing the local bar scene in Salerno. Dòmo I' Vinaino Wine Bar - Enogastronomia is another top-recommended bar that is sure to get you into the mood for some dancing and celebrating.

Say good night to Salerno and look forward to another great day of your road trip in Italy!

Dive into day 10 of your remarkable road trip in Italy. Today you will explore Pompei and Ercolano, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Naples. You’ll stay here for 2 nights.

After soaking in Salerno’s unique atmosphere, jump into the car with a full heart and drive in the direction of your next destination: Pompei. Expect your car journey to take a minimum of 39 min. When you arrive in Pompei, it's time to take a break from the road.

Make your way to Archaeological Park Of Pompeii, a locally renowned archeological site that draws attention for its historic features. Spend some time soaking in the atmosphere before continuing to Lupanare Di Pompei, a photogenic archeological site that stands out in the town. Next, visit Teatro Grande, a beloved archeological site that offers a unique experience. Be sure to also explore Amphitheatre Of Pompeii, a nearby archeological site, which is highly recommended by other travelers.

When you’ve had your share of Pompei, prepare for your next destination. Admire the views and listen to some good music as you drive in the direction of Ercolano. Your travel time is around 34 min.

Spend your afternoon discovering Vesuvio National Park, an interesting national park known for its UNESCO world heritage-designated features.

At the end of the day, you will drive to Naples, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Naples. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Set out on a gastronomic journey in Naples by reserving a table at Veritas. Renowned for its 1-star Michelin recognition, this restaurant presents an outstanding menu of campanian and contemporary cuisine. For a different taste, head over to Il Comandante, renowned for its delectable creative and mediterranean dishes. This distinguished 1-star Michelin-recipient is a favorite among guests, making it a worthy addition to your holiday plans. Craving more culinary excitement? Explore ARIA, a highly rated local gem known for its exquisite contemporary and modern menu. With a 1-star Michelin acclaim, it promises a dining experience you won't want to miss. With its reputation for pleasing customers, it’s a fantastic choice for tonight in Naples.

Cap off your culinary experience with a visit to some of the most celebrated bars in the area. For instance, Happening Cocktail Bar stands out as an excellent choice for a post-dinner cocktail. Alternatively, Shanti Art Musik Bar offers an ideal atmosphere to enjoy the pleasures of the night. Gran Caffè Gambrinus is also a great option that provides a perfect setting for a relaxing evening.

Savor another day of unforgettable experiences in Italy!

Day 11 of your road trip will take you to the best attractions Naples has to offer. Cherish the 1 night you have left in Naples by discovering the best things there are to see and do in the city.

Brace yourself for today’s incredible lineup of attractions in Naples, featuring fun adventures, romantic experiences, and scenic views. Start at Ovo Castle, a locally renowned castle in the city. Then, head to Naples National Archaeological Museum and soak in the ambiance of this detailed museum.

There are many interesting places to see in Naples and when you are ready for more, go to Cappella Sansevero. This is one of the city’s most locally renowned spots. After exploring the museum, visit the notable Napoli Sotterranea Percorso Ufficiale.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Naples. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Make sure to reserve a table at Antica Pizzeria Di Matteo, an iconic dining spot in Naples. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Mercure Napoli Centro Angioino, a popular restaurant in Naples. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of La Lazzara Trattoria e Pizzeria, a hidden gem nestled in Naples. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

After enjoying a delightful dinner, why not delve into the vibrant local bar scene? You might want to spend the evening at Archivio Storico - Cocktail Bar & Wonderfood, a well-loved spot among locals and tourists. Or, head to Archeobar. This bar boasts a welcoming environment that is perfect for winding down. You could also continue your night at Babette Pub, another top-rated place in the area.

As the sun sets on another day of adventure, rest up and recharge for the next leg of your road trip in Italy.

Embark on another extraordinary experience on day 13 of your road trip in Italy. Today, you will make 2 stops and experience some of the highlights of Santa Maria degli Angeli and Perugia. At the end of the day, you will enjoy the comforts of a top-rated hotel in Florence, which will be your home away from home for 1 night.

Today’s route brings fun adventures, picturesque spots, and historic treasures. The first attraction of today is Rocca Paolina. This often recommended historical landmark is a symbolic place to see in Perugia. Continue your discovery at Piazza Iv Novembre, a history-steeped public square with stories to tell.

As you stroll around Perugia, take in the distinct atmosphere and learn what makes this town so unique. Maximize your sightseeing with a visit to Acquedotto Medievale Di Perugia. This locally appreciated historical landmark offers a breathtaking encounter with Perugia.

Continue your road trip and head to your next destination, Santa Maria degli Angeli. This car ride takes around 32 min.

Your self-guided tour starts at Basilica Of San Francesco D'assisi, a locally renowned church that is sure to impress. Take in the surroundings and enjoy the freedom of exploring before you continue your journey.

Fasten your seatbelt and make your way to your next stop. Santa Maria degli Angeli, home to many well-known sights in the region, is a lovely destination on today’s itinerary. Keep in mind that your travel time from Santa Maria degli Angeli to Santa Maria degli Angeli may take around 9 min without traffic disruptions. Upon arrival in Santa Maria degli Angeli, we highly recommend checking out some of the top attractions.

One of our top recommendations for your sightseeing is Basilica Of Santa Maria Degli Angeli. Spend some time admiring the picture-perfect features of the church before you continue to your next stop.

After soaking up all the sights of today's itinerary, you'll be ready to hit the road in the direction of your accommodation in Florence. Florence offers plenty of top-rated hotels and other places to stay on any travel budget. Take some time to relax before you head out to explore.

Indulge in a memorable dining experience at one of Florence's most popular restaurants, and connect with friendly locals for an authentic adventure.

Savor the flavors at Ristorante Buca Mario, a top pick for dinner tonight. Alternatively, Agricola Toscana beckons with its unique menu offerings. Also, consider Eataly Firenze. With its consistent customer satisfaction, it’s an excellent option for dining in Florence tonight.

Keep the excitement of the evening going by visiting a bar or two. Gosh* is an excellent place to start. You could also check out Antico Caffè Del Moro - Art Bar Firenze, offering a different kind of charm. A last recommendation for the day is Quelo Bar. This bar promises an enjoyable experience with tasty drinks and a vibrant setting.

Take some time to reflect on your day and savor another beautiful night in Italy.