14-Day Italy Self-Drive Road Trip With Itinerary from Florence traveling south to Pisa, Rome, Province of Salerno, Naples, and Perugia

Day 2 offers a multitude of experiences. You will stay in Florence for 1 night more, offering you enough time to explore at a relaxed pace.

Enjoy the perfect balance of relaxation and exploration in Florence today. One of the most top-rated attractions included on the itinerary is Piazza Della Signoria. This visually striking public square will help you start your sightseeing on top. Then, take a leisurely stroll to Uffizi Gallery and learn what makes this historic art gallery unique.

Throughout the day, make sure to take breaks to appreciate the surroundings. Next up, visit the iconic Ponte Vecchio. After exploring the historical landmark, head to Pitti Palace. This popular palace is a highlight in Florence. Lastly, don’t forget to check out the well-known The Boboli Gardens. Enjoy exploring this incredible botanical garden at your own pace.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

As dinnertime approaches, it's time to head out for a bite to eat in Florence. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Set out on a gastronomic journey in Florence by reserving a table at Enoteca Pinchiorri. Renowned for its 3-star Michelin recognition, this restaurant presents an outstanding menu of italian contemporary cuisine. For a different taste, head over to Santa Elisabetta, renowned for its delectable creative and mediterranean dishes. This distinguished 2-star Michelin-recipient is a favorite among guests, making it a worthy addition to your holiday plans. Craving more culinary excitement? Explore Gucci Osteria da Massimo Bottura, a highly rated local gem known for its exquisite italian contemporary and international menu. With a 1-star Michelin acclaim, it promises a dining experience you won't want to miss. With its reputation for pleasing customers, it’s a fantastic choice for tonight in Florence.

After savoring a delicious meal, step into the vibrant nightlife at Bar 50 Rosso, where the evening is just getting started. In the same way, Bitter Bar offers a unique charm perfect for experiencing the local bar scene in Florence. Archea Brewery is another top-recommended bar that is sure to get you into the mood for some dancing and celebrating.

Get a good night's sleep and look forward to another great day on the road in Italy!

On day 3 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 1 destination, Florence. When you’re not sightseeing, take time to relax at your selected hotel in Pisa, where you’ll be staying for 1 night.

Get ready for a day filled with an eye-catching, a historic, a culturally significant, a culturally significant, a masterful, a charming, a stunning, and an UNESCO world heritage-designated in the charming city of Florence. Your adventure starts at Basilica Of Santa Croce In Florence, a well-known local hot spot. Another notable attraction to explore is Galleria Dell'accademia. This captivating art gallery is known for its photogenic appeal.

After soaking in the highlights of these sights, take some time to wander Florence's streets and immerse yourself in the local atmosphere. When you're ready to continue your sightseeing adventure, head to Cathedral Of Santa Maria Del Fiore. This inviting church offers a fascinating experience that many visitors find memorable. Basilica Di Santa Maria Novella, Firenze (fi) is also worth visiting.

At the end of the day, you will drive to Pisa, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As you explore more of Pisa, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Have a fantastic dining experience at Anima di Grano Pizzeria Napoletana Pisa Italy, a highly recommended choice for tonight's dinner. If you're looking to mix things up, il Mercante offers an enticing alternative with its varied menu. Additionally, La Ghiotteria is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Pisa.

If you’re not ready to end the night just yet, Jeffer Cocktails & Friends offers a perfect venue to relax and savor a drink. Similarly, Le Parisien Wine Bar is well-suited for those looking to unwind in a social setting. Las Volta Cocktailbar is another excellent spot to enjoy a nightcap after a delightful meal.

As the sun sets on another day of adventure, rest up and recharge for the next leg of your road trip in Italy.

Embark on another extraordinary experience on day 4 of your road trip in Italy. Today, you will make 1 stop and experience some of the highlights of Pisa. At the end of the day, you will enjoy the comforts of a top-rated hotel in Rome, which will be your home away from home for 5 nights.

Pisa is home to plenty of attractions that offer a mesmerizing, an eye-catching, a standout, a symbolic, a noteworthy, an UNESCO world heritage-designated, and a stunning! Start at Knights' Square, an intriguing public square that is worthwhile a visit in the city. Nearby, you’ll find Leaning Tower Of Pisa, enchanting visitors with its culturally significant appeal. Continue your exploration at Piazza Del Duomo, Pisa. This public square is one of the city’s most wondrous spots.

Enjoy the freedom of exploring Pisa at your own pace and find hidden gems along the way. If you want to see more picture-perfect spots, make sure to visit Pisa Cathedral.

After soaking up all the sights of today's itinerary, you'll be ready to hit the road in the direction of your accommodation in Rome. Rome offers plenty of top-rated hotels and other places to stay on any travel budget. Take some time to relax before you head out to explore.

As dinnertime approaches, it's time to head out for a bite to eat in Rome. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Experience a symphony of flavors at La Pergola in Rome by securing a reservation in advance. Renowned for its 3-star Michelin distinction, La Pergola delights its guests with its exceptional variety of meals showcasing delicious mediterranean and contemporary cuisine. For a palate-pleasing alternative, make sure to dine at Il Pagliaccio, acclaimed for its delectable creative and innovative specialties. This local 2-star Michelin establishment consistently satisfies guests, ensuring an unforgettable holiday experience. Want to go on another culinary journey? Delight your senses at Enoteca La Torre, a top-rated restaurant known for its outstanding menu. Known as a top-rated 2-star Michelin establishment, it's a top choice for mediterranean and creative cuisine in the city.

After your delicious meal, get a taste of the vibrant nightlife with a visit to La Botticella Of Poggi Giovanni, known for its inviting atmosphere. Almalu Trastevere is another great option if you’re looking for a place to get the night started. Similarly, Bar Viminale Di Pepi Maurilio provides a great setting to enjoy the night away.

Get a good night's sleep and look forward to another great day on the road in Italy!

Greet day 5 of your road trip in Italy with a smile and start your day with a hearty breakfast. You will return to Rome for your remaining 4 nights in the city later today, but first, it’s time for some exploring! On the agenda for this day, you’ll find only the best things to see and do in Vatican City and Rome.

Prepare for a day full of a charming, a mesmerizing, an eye-catching, a heritage-rich, a symbolic, and a masterful. When you’re ready, kick off your sightseeing adventure at Trevi Fountain. This globally renowned monument is a must-visit for anyone seeking a unique vacation experience.

Continue your road trip and head to your next destination, Vatican City, Vatican City. This car ride takes around 11 min.

After taking in the atmosphere, continue to Sistine Chapel, a famous chapel that is a must-see for anyone visiting the region. Make sure to also explore Vatican Museums, a globally renowned art museum that offers a unique experience.

When you’re done exploring for the day, you’ll return to Rome and your accommodation.

As dinnertime approaches, it's time to head out for a bite to eat in Rome. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Make sure to reserve a table at RomAntica, an iconic dining spot in Rome. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Coso Ristorante, a popular restaurant in Rome. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of DEROMA - Farine Romane, a hidden gem nestled in Rome. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Explore the vibrant nightlife at Sant' Eustachio Caffè after your meal, a hub for lively evenings and memorable moments. Or, head to Yellowsquare Rome for a great selection of flavorful drinks and a charming setting. Furthermore, Caffè Portofino is perfect for those looking to extend their night with a touch of local flavor.

Raise your glass to another unforgettable day in Italy!

On day 6 of your road trip, you will have an entire day to explore Rome. You’ll stay in Rome for 3 nights and discover all the best things to see and do in the area.

Today’s route brings a romantic, a stunning, an instagrammable, a respected, a majestic, and an inviting. The first attraction of today is Spanish Steps. This famous public square is a romantic place to see in Rome. Continue your discovery at Piazza Di Spagna, a romantic public square with stories to tell.

As you stroll around Rome, take in the distinct atmosphere and learn what makes this city so unique. Maximize your sightseeing with a visit to Pantheon. This globally renowned monument offers a heritage-rich encounter with Rome. Largo Di Torre Argentina is the last of our recommendations for today. Whether you decide to get entrance tickets for all attractions or you prefer admiring from a distance, amazing experiences await on this day in Rome.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

Indulge in a memorable dining experience at one of Rome's most popular restaurants, and connect with friendly locals for an authentic adventure.

Make sure to reserve a table at Hotel de Russie, an iconic dining spot in Rome. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of La Taverna Italiana, a popular restaurant in Rome. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of The Parrot Bar, a hidden gem nestled in Rome. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

After enjoying a delightful dinner, why not delve into the vibrant local bar scene? You might want to spend the evening at The Apartment Bar Roma, a well-loved spot among locals and tourists. Or, head to Hotel Hassler Roma. This bar boasts a welcoming environment that is perfect for winding down.

Raise your glass to another unforgettable day in Italy!

Day 7 of your road trip across Italy promises a magnificent time exploring Rome. You have 2 nights left in Rome. Take the opportunity to experience more of the best attractions and activities in the city.

Today, you'll explore some of the most beautiful places in Rome, including a monument, a public square, and an archeological site. Start your day with a visit to Altare Della Patria. This notable monument is a must-visit in the city. When you’re ready for your next discovery, continue to Capitoline Hill, which may be one of the most romantic places you will experience today.

One of the best things about exploring Rome on a self-guided tour is that you set the pace. There’s plenty of time for detours and discovering hidden gems. When you’re ready for your next stop, make your way to Roman Forum, one of the city’s most globally renowned archeological site. If you’re up for more discoveries, don’t forget to reserve some time for Colosseum and Circus Maximus.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

After a day of adventure, treat yourself to an exquisite dinner at one of Rome's best restaurants.

Enjoy a delicious meal at Sofitel Roma Villa Borghese, a top-rated dining destination in Rome. If you're in the mood to try something new, consider Centro, another top spot with a mouthwatering menu. You might also want to secure a reservation at Ristorante Tema. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Rome this evening.

Say good night to Rome and look forward to another great day of your road trip in Italy!

Day 8 of your road trip will take you to the best attractions Rome has to offer. Cherish the 1 night you have left in Rome by discovering the best things there are to see and do in the city.

Today’s well-planned self-sightseeing route offers several a charming, a scenic, a stunning, an eye-catching, a standout, a masterful, and a majestic. Whether you decide to explore Rome on foot, use public transport, or join a guided tour, there are a few attractions you don’t want to miss. Villa Borghese is the first of them. Spend some time admiring this mesmerizing park before continuing your journey. Piazza Del Popolo is your next stop. This spectacular public square is one of the best-rated sights in Rome.

Consider grabbing some lunch or a light snack to keep your energy going. Beyond the above-mentioned attractions, today is also the perfect time to visit Castel Sant'angelo. This visually striking castle is a sight to behold. To round off your sightseeing experience, visit Piazza Navona and Campo De' Fiori.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

As you explore more of Rome, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Enjoy a delicious meal at Ristorante Va. Do. , a highly-rated dining destination in Rome. If you're eager to try something different, consider Giulia Restaurant, another top spot with a tantalizing menu. You might also want to secure a reservation at L'Archeologia. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Rome this evening.

Savor another day of unforgettable experiences in Italy!

Dive into day 9 of your remarkable road trip in Italy. Today you will explore Paestum and Province of Salerno, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Province of Salerno. You’ll stay here for 1 night.

Once you're ready to continue your road trip, it's time to buckle up and drive, eagerly anticipating your arrival in Paestum. This drive usually takes around 3 hours 27 min, without any stops or traffic disruptions.

Make your way to Second Temple Of Hera, a worthwhile archeological site that draws attention for its majestic features. Spend some time soaking in the atmosphere before continuing to Archaeological Park Of Paestum, a culturally significant archeological site that stands out in the hamlet.

When you’re ready to jump back into the car and say goodbye to Paestum, you’ll hit the road in the direction of Province of Salerno. This drive usually takes around 50 min. When you arrive, enjoy some sightseeing.

Head to Cathedral Of Santa Maria Degli Angeli, San Matteo And San Gregorio Vii, a frequently visited church in Province of Salerno. Explore its picture-perfect features at your own pace before you continue your journey.

When you’re done exploring for the day, you’ll drive to your hotel in Province of Salerno. Check in and spend some time relaxing before you head out to tour the city.

After a day of adventure, treat yourself to an exquisite dinner at one of Province of Salerno's best restaurants.

Enjoy an outstanding dining experience at Re Maurì, a 1-star Michelin restaurant offering an exceptional creative menu. Alternatively, experience a taste of Province of Salerno at L'Unico Drink & Food Salerno, a popular local restaurant. With a menu designed to impress, it promises a journey of flavors that will leave you captivated.

After enjoying a fulfilling meal, continue your evening at Hilton Bar E Gastronomia, ideal for those looking to unwind with a drink in a comfortable setting. Alternatively, The Black Monday Speakeasy Tbm offers a welcoming atmosphere for easing into the nightlife. Similarly, Dòmo I' Vinaino Wine Bar - Enogastronomia provides an excellent environment for a relaxed and enjoyable evening.

Savor another day of unforgettable experiences in Italy!

Experience an unparalleled adventure on day 10 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 2 vibrant destinations - Pompei and Ercolano. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Naples. You will spend 2 nights here for some well-deserved relaxation.

As you’ve unraveled the marvels of Province of Salerno, it’s time to gear up for the next part of your road trip adventure. Under favorable conditions, your drive to Pompei may take around 39 min. Upon your arrival in Pompei, you’ll be greeted with the opportunity to do some sightseeing and exploring.

Begin your journey at Archaeological Park Of Pompeii and explore the picture-perfect features. Next, make your way to Lupanare Di Pompei, another highlight in the town. When you’re done exploring the archeological site, continue to Teatro Grande, an UNESCO world heritage-listed archeological site. Nearby, you will also find Amphitheatre Of Pompeii. This locally renowned archeological site is a top place to see in the area.

Ercolano’s wonders await as you prepare for another journey on the road, leaving the breathtaking surroundings of Pompei behind. This drive usually takes around 34 min. Ercolano welcomes you with a multitude of unique vacation experiences.

Make your way to Vesuvio National Park, a notable national park that draws attention for its history-steeped features.

At the end of the day, you will drive to Naples, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

Indulge in a memorable dining experience at one of Naples's most popular restaurants, and connect with friendly locals for an authentic adventure.

Get ready for an unforgettable culinary journey in Naples by reserving a table at Veritas. Renowned as a 1-star Michelin restaurant, it offers an exceptional campanian and contemporary menu. For a different taste experience, head to Il Comandante, recognized for its delicious creative and mediterranean dishes. This 1-star Michelin restaurant consistently impresses guests, ensuring a memorable addition to your holiday. Looking for another option? Make sure to visit ARIA, a local favorite known for its delightful contemporary and modern cuisine in Naples. Nestled in the heart of the city, this restaurant with 1 Michelin star is an ideal choice for discerning contemporary and modern foodies seeking culinary excellence.

Round off your dining experience by visiting Happening Cocktail Bar, a prime location for a drink. Alternatively, explore the distinctive characteristics of Shanti Art Musik Bar, a bar catering to every mood and preference. Gran Caffè Gambrinus likewise offers a unique atmosphere, perfect for a memorable night out.

Head back to your accommodation in Naples and get some rest in preparation for another magical day of your road trip in Italy!

Day 11 offers a multitude of experiences. You will stay in Naples for 1 night more, offering you enough time to explore at a relaxed pace.

Prepare for a day full of a romantic, an awe-inspiring, an eye-catching, a heritage-rich, a symbolic, and a masterful. When you’re ready, kick off your sightseeing adventure at Ovo Castle. This locally renowned castle is a must-visit for anyone seeking a unique vacation experience. Another sight you shouldn’t miss is Naples National Archaeological Museum, one of the city’s most promising highlights.

Next, check out Cappella Sansevero, one of the most notable places to see in Naples. This museum is a favorite among locals and travelers alike. Enjoy some downtime and refreshments before continuing to your next stop, Napoli Sotterranea Percorso Ufficiale. Wander around and soak in the heritage-rich atmosphere this cave system offers. Finally, take the path to the widely recognized Piazza Del Plebiscito, the last of our attraction recommendations for today.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Naples. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Treat yourself to a delightful dinner at Antica Pizzeria Di Matteo, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Mercure Napoli Centro Angioino? It's another excellent option with a diverse menu. Consider reserving a table at La Lazzara Trattoria e Pizzeria as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Naples.

Let the evening flow smoothly from dinner to drinks at Archivio Storico - Cocktail Bar & Wonderfood, a top-rated bar in the area. For other recommendations, Archeobar provides a perfect setting for rounding out your night with style and great drinks. Likewise, Babette Pub offers a memorable night with diverse drink options and excellent service.

As the sun sets on another day of adventure, rest up and recharge for the next leg of your road trip in Italy.

On day 13 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 2 destinations, Santa Maria degli Angeli and Perugia. When you’re not sightseeing, take time to relax at your selected hotel in Florence, where you’ll be staying for 1 night.

Enjoy the perfect balance of relaxation and exploration in Perugia today. One of the most underrated attractions included on the itinerary is Rocca Paolina. This eye-catching historical landmark will help you start your sightseeing on top. Then, take a leisurely stroll to Piazza Iv Novembre and learn what makes this visually striking public square unique.

Throughout the day, make sure to take breaks to appreciate the surroundings. Next up, visit the underrated Acquedotto Medievale Di Perugia.

Embrace the thrill of the open road as you wave goodbye to Perugia and set your GPS to Santa Maria degli Angeli. While on the road, immerse yourself in your favorite road trip tunes or sample the sounds from a local radio station. This car ride usually takes around 32 min. Upon reaching Santa Maria degli Angeli, unwind, observe, and explore. The best things to do, see, and eat are waiting for you.

Spend your afternoon discovering Basilica Of San Francesco D'assisi, a locally renowned church known for its historic features.

As you’ve unraveled the marvels of Santa Maria degli Angeli, it’s time to gear up for the next part of your road trip adventure. Under favorable conditions, your drive to Santa Maria degli Angeli may take around 9 min. Upon your arrival in Santa Maria degli Angeli, you’ll be greeted with the opportunity to do some sightseeing and exploring.

One of our top recommendations for your sightseeing is Basilica Of Santa Maria Degli Angeli. Spend some time admiring the picture-perfect features of the church before you continue to your next stop.

When you’re done exploring for the day, you’ll drive to your hotel in Florence. Check in and spend some time relaxing before you head out to tour the city.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Florence. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Enjoy a lovely meal at Ristorante Buca Mario, a top-rated place to have dinner tonight. Alternatively, if your taste buds call for something different, Agricola Toscana is another top choice with a popular menu. You could also check for a table at Eataly Firenze. As an establishment that gains consistently high praises from customers, it’s an ideal choice in Florence tonight.

After savoring a delicious meal, step into the vibrant nightlife at Gosh*, where the evening is just getting started. In the same way, Antico Caffè Del Moro - Art Bar Firenze offers a unique charm perfect for experiencing the local bar scene in Florence. Quelo Bar is another top-recommended bar that is sure to get you into the mood for some dancing and celebrating.

Raise your glass to another unforgettable day in Italy!