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Road trips in Italy

4-Day Italy Self-Drive Road Trip With Itinerary from Genoa to Pisa

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Photo of Sand beach in Camogli by Genoa, Italy.

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Escape the ordinary with this exciting 4-day road trip through Italy. Explore the diverse landscapes, lively cities, and beyond. Pack your bags, hit the road, and prepare for an unforgettable journey!

This perfectly planned road trip itinerary in Italy takes you through some of the best places to see in the country. You will spend 2 nights in Genoa and 1 night in Pisa. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Italy. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have got you covered.

Upon arriving in Genoa, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Italy on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Italy. Ponte Vecchio and Leaning Tower Of Pisa are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Piazza Del Duomo, Pisa, learn more about the unique Piazzale Michelangelo, and immerse yourself in the vibrant atmosphere of Uffizi Gallery.

As you hit the open road and drive through Genoa, Manarola, Pisa, Florence, and San Gimignano, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Italy. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Italy.

Throughout your road trip in Italy, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Italy.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodation, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Italy fill up quickly, so book your spot early. Select a date and start planning your road trip in Italy today!

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Driver’s age is 30 - 65

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Days

Destination

Attractions

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Day

City & Overnight

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Day 1

Aquarium of Genoa

Day 2

Manarola Overlook Viewpoint•Pisa Cathedral•Piazza del Duomo, Pisa•Leaning Tower of Pisa•Knights' Square•Santa Maria della Spina

Day 3

Ponte Vecchio•Uffizi Gallery•piazzale Michelangelo•SanGimignano1300

Day 4

piazza De Ferrari

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Day 1

Genoa - Arrival day
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Aquarium of Genoa
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Welcome to Genoa, the perfect starting point for your road trip in Italy! Pick up your rental car and let the adventure begin. You will spend 1 night immersing yourself in Genoa's charm before embarking on the next leg of your journey.

Genoa is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Aquarium Of Genoa, or just taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

As afternoon approaches, head to your chosen hotel in Genoa. Check-in typically starts around 2 to 4 PM at hotels in Italy. We recommend staying at a hotel in a central location for easy access to the best attractions, restaurants, and bars in the city.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Genoa, it's often a good idea to reserve a table in advance.

Enjoy a delicious meal at 7 Sensi cucina decontaminata, a top-rated dining destination in Genoa. If you're in the mood to try something new, consider Alla Lunga Ristorante, another top spot with a mouthwatering menu. You might also want to secure a reservation at Grand Hotel Savoia. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Genoa this evening.

Unwind after your meal by stepping into Scurreria Beer & Bagel. This venue is celebrated for its extensive drink selections and cozy vibes. Alternatively, La Lepre offers a dynamic and energetic atmosphere for a glass or two. Don’t overlook Bar Pisacane Iii, another top-rated bar in the area.

Raise a toast to the start of your 4-day road trip in Italy!

Day 2

Genoa
Pisa
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Drive 220 km, 4 hours 2 min

Manarola Overlook Viewpoint
Pisa Cathedral
Piazza del Duomo, Pisa
Leaning Tower of Pisa
Knights' Square
Santa Maria della Spina
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Embark on another extraordinary experience on day 2 of your road trip in Italy. Today, you will make 2 stops and experience some of the highlights of Manarola and Pisa. At the end of the day, you will enjoy the comforts of a top-rated hotel in Pisa, which will be your home away from home for 1 night.

Today’s route brings fun adventures, romantic experiences, and natural wonders. The first attraction of today is Manarola Overlook Viewpoint. This intriguing observation deck is a romantic place to see in Genoa. Continue your discovery at Pisa Cathedral, an UNESCO world heritage-designated church with stories to tell.

As you stroll around Genoa, take in the distinct atmosphere and learn what makes this village so unique. Maximize your sightseeing with a visit to Piazza Del Duomo, Pisa. This wondrous public square offers a stunning encounter with Genoa. Next, make your way to Leaning Tower Of Pisa to add another highlight to your day. After that, visit Knights' Square, an often recommended public square that’s sure to impress. If you’re up for more, end your self-guided sightseeing tour at Santa Maria Della Spina, a worthwhile church in the village. Whether you decide to get entrance tickets for all attractions or you prefer admiring from a distance, amazing experiences await on this day in Genoa.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Pisa. Pisa offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Pisa. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Treat yourself to a delightful dinner at Anima di Grano Pizzeria Napoletana Pisa Italy, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try il Mercante? It's another excellent option with a diverse menu. Consider reserving a table at La Ghiotteria as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Pisa.

Round off your dining experience by visiting Jeffer Cocktails & Friends, a prime location for a drink. Alternatively, explore the distinctive characteristics of Le Parisien Wine Bar, a bar catering to every mood and preference. Las Volta Cocktailbar likewise offers a unique atmosphere, perfect for a memorable night out.

Get a good night's sleep and look forward to another great day on the road in Italy!

Day 3

Pisa
Genoa
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Drive 377 km, 5 hours 37 min

Ponte Vecchio
Uffizi Gallery
piazzale Michelangelo
SanGimignano1300
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Dive into day 3 of your remarkable road trip in Italy. Today you will explore Florence and San Gimignano, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Genoa. You’ll stay here for 1 night.

Immerse yourself in Pisa’s rich culture with today's sightseeing itinerary. Start your journey at Ponte Vecchio. This history-steeped historical landmark is sure to ignite your curiosity. Next, dive into the romantic features of Uffizi Gallery, a must-visit art gallery in the city.

In between sights, stop by local stores, picturesque photo spots, and small eateries. When you’re ready for your next attraction, proceed to Piazzale Michelangelo, an extraordinary observation deck. For a change of scene, check out Sangimignano1300, known for its visually striking features.

At the end of the day, you will drive to Genoa, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

After a day of adventure, treat yourself to an exquisite dinner at one of Genoa's best restaurants.

Don’t miss out on dining at Zeffirino, a top-rated dining destination in Genoa. If you're in the mood to try something new, consider Trattoria Vegia Zena, another top spot with a mouthwatering menu. You might also want to secure a reservation at Trattoria delle Grazie. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Genoa this evening.

Relax and recharge in preparation for another adventurous day in Italy!

Day 4

Genoa - Departure day
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piazza De Ferrari
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Day 4 of your road trip in Italy is your departure day. This is your chance to catch a last glimpse of Genoa before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, we recommend visiting Piazza De Ferrari, a romantic public square before you head out.

Maximize your last day in Italy and go on a shopping spree in Genoa’s shopping center, the lively Via Garibaldi. Browse for souvenirs to remind you of your wonderful journey in Italy. Discover boutiques with stylish fashion choices to upgrade your wardrobe.

Before you conclude your road trip in Italy, drop by another restaurant for a last chance at a memorable dining experience in Genoa.

Enjoy a lovely meal at Osteria Sant'Ilario, a top-rated place to have dinner tonight. Alternatively, if your taste buds call for something different, La Cialtroneria is another top choice with a popular menu.

You’ll then say farewell to Genoa. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Italy!

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