4-Day Sicily Road Trip from Palermo to Agrigento
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Escape the ordinary with this exciting 4-day road trip through Sicily. Explore the diverse landscapes and local cultures of Palermo, Agrigento, Monreale, and Isola delle Femmine. Pack your bags, hit the road, and prepare for an unforgettable journey!
This perfectly planned road trip itinerary in Sicily takes you through some of the best places to see in the country. You will spend 2 nights in Palermo, and 1 night in Agrigento. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!
With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Sicily. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have got you covered.
Upon arriving in Palermo, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Sicily on your own terms.
An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Sicily. Valle Dei Templi and Palermo Cathedral are just a couple of the bucket-list attractions that await your discovery.
As you hit the open road and drive through Palermo, Agrigento, Monreale, and Isola delle Femmine, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Sicily. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Sicily.
Throughout your road trip in Sicily, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Sicily.
This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodation, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.
The best services in Sicily fill up quickly, so book your spot early. Select a date and start planning your road trip in Sicily today!
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Customize tours under each day and destination
Day 1 – Palermo - arrival day
- Palermo - Arrival day
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- Foro Italico
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Welcome to Palermo, the perfect starting point for your road trip in Italy! Pick up your rental car and let the adventure begin. You will spend 1 night immersing yourself in Palermo's charm before embarking on the next leg of your journey.
Palermo is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Foro Italico or taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.
Find your way to your hotel in Palermo. We recommend choosing a hotel in a central location for easy exploring. Check-in typically starts between 2 and 4 PM at hotels in Italy. Settle in and make plans for the evening.
As dinnertime approaches, it's time to head out for a bite to eat in Palermo. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.
Treat yourself to a delightful dinner at Eremiti Restaurant, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Osteria Mercede? It's another excellent option with a diverse menu. Consider reserving a table at Trattoria Del Massimo as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Palermo.
Continue your evening by exploring the vibrant nightlife scene at Malox Cult, a prime destination for a thrilling night out. Also, don’t forget to check out Ai Giudici, a bar that offers unique local touches. Likewise, Bar Italico provides an excellent alternative for a fun evening.
Raise a toast to the start of your 4-day road trip in Sicily!
Day 2 – Palermo, and Agrigento
- Agrigento
- Palermo
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Drive 137 km, 2 hours 31 min
- Norman Palace
- Palermo Cathedral
- Orto botanico di Palermo
- Catacombe dei Cappuccini
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Experience an unparalleled adventure on day 2 of your road trip in Sicily. This exciting part of your journey invites you to discover the renowned landmarks in 1 vibrant destinations - Palermo. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Agrigento. You will spend 1 night here for some well-deserved relaxation.
Kick off the day at Norman Palace, a top pick for today’s sightseeing. This museum is rated an average of 4.5 out of 5 stars in 19,949 reviews.
Today is also your chance to visit Palermo Cathedral. Palermo Cathedral is a cathedral with an average rating of 4.7 out of 5 stars from 35,799 reviews.
Orto Botanico Di Palermo is another top attraction we highly recommend you visit today. This botanical garden is rated an average of 4.4 out of 5 stars by 6,568 visitors.
Beyond the attractions mentioned above, you also have the opportunity to visit Catacombe Dei Cappuccini. This museum is rated an average of 4.3 out of 5 stars by 10,859 visitors.
After soaking up all the sights of today's itinerary, you'll be ready to hit the road in the direction of your accommodation in Agrigento. Agrigento offers plenty of top-rated hotels and other places to stay on any travel budget. Take some time to relax before you head out to explore.
As you explore more of Agrigento, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.
Dive into a culinary adventure like no other in Agrigento by booking a table at Osteria Expanificio. This popular restaurant holds a Bib Gourmand award and offers an exceptional menu of sicilian, and traditional cuisine. If you're in the mood to try something new, consider Le Cuspidi, another top spot with a mouthwatering menu.
Relax and recharge in preparation for another adventurous day in Sicily!
Day 3 – Agrigento, Scavuzzo, Monreale, Isola delle Femmine, and Palermo
- Palermo
- Agrigento
- Monreale
- Isola delle Femmine
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Drive 212 km, 3 hours 37 min
- Scala dei Turchi
- Valle dei Templi
- Cattedrale di Monreale
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Embark on another extraordinary experience on day 3 of your road trip in Sicily. Today, you will make 4 stops and experience some of the highlights of Scavuzzo, Agrigento, Monreale, and Isola delle Femmine. At the end of the day, you will enjoy the comforts of a top-rated hotel in Palermo, which will be your home away from home for 1 night.
Seize the day by visiting some of the best attractions in the area, like Valle Dei Templi. This extraordinary archaeological site has an average rating of 4.7 out of 5 stars from 45,296 visitors. Each year, around 445,925 people visit this remarkable site to admire its features and learn more about it.
Continue your road trip and head to your next destination, Scavuzzo.
Take the opportunity to see Scala Dei Turchi. This attraction has an average rating of 4.6 out of 5 stars from 8,901 visitors.
At the end of the day, you will drive to Palermo, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.
As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Palermo. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.
Treat yourself to an extraordinary dining experience at Buatta Cucina Popolana, a Bib Gourmand restaurant offering an incredible sicilian menu. Alternatively, if your taste buds call for something different, Mec Restaurant is one of the best restaurants for sicilian, and contemporary cuisine in Palermo. This 1-star Michelin-awardee earns consistently high praises from guests. We also recommend checking out the menu at Gagini Restaurant. As a top-rated establishment with 1 Michelin star, it is an ideal choice for creative, and contemporary cuisine in the city.
If you’re not ready to end the night just yet, Spina Bar Palermo offers a perfect venue to relax and savor a drink. Similarly, Monkey Pub is well-suited for those looking to unwind in a social setting. Bar Touring is another excellent spot to enjoy a nightcap after a delightful meal.
Say good night to Palermo and look forward to another great day of your road trip in Sicily!
Day 4 – Palermo - departure day
- Palermo - Departure day
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- Quattro Canti
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Day 4 of your road trip in Sicily is your departure day. This is your chance to catch a last glimpse of Palermo before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.
Make the most of your final day in Sicily by visiting Palermo’s iconic markets and shopping establishments. Secure the perfect souvenirs for your family and friends back home or buy yourself a remembrance of your amazing experience in Sicily.
Make Quattro Canti one of your first sightseeing stops in Palermo. Rated an average of 4.6 out of 5 stars by 21,970 travelers, a visit to this local attraction makes for a great introduction to the area.
Before you conclude your road trip in Sicily, drop by another restaurant for a last chance at a memorable dining experience in Palermo.
Treat yourself to a delicious dinner at CUMA Natural Bar & Fresh Market, an excellent option for tonight's dining. Looking for something different? Sikulo offers a tantalizing alternative with its diverse menu. And don’t miss Vespa Café.
You’ll then say farewell to Palermo. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Sicily!
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