5-Day Italy road trip from Ancona to Perugia and Rome

Ancona has many popular destinations you can explore. You could visit attractions like the incredible Lazzaretto of Ancona. This attraction is a building and has an average rating of 4.4 out of 5 stars by 4,023 visitors.

Your stay promises to be a delightful continuation of your exploration, providing comfort and tranquility to recharge for the adventures that lie ahead.

Ancona also has several great bars that will fit all travel budgets. One of the best bars in the city of Ancona is Donegal Irish Pub. This bar has an average rating of 4.3 out of 5 stars by 1,118 customers.

Another of the best bars in the city of Ancona is Posa bar. This bar is rated an average of 4.5 out of 5 stars by 948 customers.

Enjoy toasting the start of your 5-day vacation in Italy!

Day 2 of your road trip through Italy gives you the opportunity to experience two places in one day. You will stay in Perugia for 1 night. Have a hearty breakfast and get excited for a wonderful day ahead!

One of the best places to visit today in Ancona is the amazing Sanctuary of the Holy House of Loreto. This attraction is a church that is rated an average of 4.8 out of 5 stars by 19,100 visitors.

You could also stop at the incredible park, Parco Naturale Regionale Gola della Rossa e di Frasassi. With an average rating of 4.6 out of 5 stars by 3,515 visitors, this attraction is one of the top sights in the area.

Another unforgettable travel destination in the Ancona is the outstanding Frasassi Caves. This popular show cave and travel destination has an average rating of 4.8 out of 5 stars by 20,728 visitors.

There are many top-rated experiences you can include in your travel plan to add flavor to your road trip in Italy. Browse all of your options and reserve your slot before it's too late.

At the end of the day, you will drive to the city of Perugia, where you will access the best hotels and places to stay.

After a long day of driving and exploring, we recommend you try Al Mangiar Bene, one of the best restaurants in the city of Perugia. This restaurant has an average rating of 4.5 out of 5 stars by 1,395 customers.

Locals also recommend La Prosciutteria Perugia as one of the best restaurants in the city of Perugia. La Prosciutteria Perugia is rated an average of 4.6 out of 5 stars by 407 customers.

Another of the best restaurants in the city of Perugia is Alphaville. This restaurant has been rated an average of 4.7 out of 5 stars by 325 customers.

After dinner, visit Quei Bravi Ragazzi, which is considered one of the best bars in the city of Perugia. This bar is rated an average of 4.7 out of 5 stars by 543 customers.

You can also enjoy drinks at a popular bar like Elfo Pub Perugia. This bar has an average rating of 4.6 out of 5 stars by 754 customers.

Alternatively, Punto di Vista is one of the best bars that locals recommend in the city of Perugia. This bar is rated an average of 4.5 out of 5 stars by 502 customers.

Raise your glass in celebration of your incredible road trip adventure through Italy!

Rise and shine on day 3 of your road trip in Italy. Today, you'll wake up in Perugia and embark on a scenic drive to Rome, where you'll stay at one of the best hotels for 1 night. Seize the opportunity to explore spectacular attractions in Perugia and Vatican before you reach your end destination for the day.

It’s hard not to feel excited about visiting attractions in a destination as lovely as Perugia. When you’re eager to explore the city and nearby areas, we recommend visiting some local favorites, such as the wonderful Piazza IV Novembre. This attraction is a square that has an average rating of 4.6 out of 5 stars from 9,189 visitors.

You could also stop at the incredible Rocca Paolina. This attraction, a beloved rocca, has an average rating of 4.7 out of 5 stars from 7,128 visitors.

If you have time, another site you could explore in Perugia is the stunning Carducci Gardens. This park and travel destination has an average rating of 4.5 out of 5 stars by 1,768 visitors.

One of the most popular attractions you can visit is the remarkable Vatican Museums. This attraction is an art museum that has an average rating of 4.6 out of 5 stars from 133,310 visitors. Around 1,612,530 people visit Vatican Museums every year.

If you want to explore more, visit the incredible Saint Peter's Square. This square and attraction has an average rating of 4.8 out of 5 stars from 38,954 reviews.

Another site you could visit today is the top-rated Sistine Chapel. This chapel and travel destination is rated an average of 4.7 out of 5 stars by 52,083 visitors.

The lovely St. Peter's Basilica is yet another attraction you could pay a visit. Around 131,043 visitors have left this major basilica an average rating of 4.8 out of 5 stars. This popular attraction gets around 11,000,000 visits every year.

When you're done with your sightseeing in Vatican, it's time to continue your drive to the city of Rome. When you arrive in Rome you’ll check in at one of the best hotels in the area.

We recommend you end the day with a dinner at a popular restaurant near your accommodation, like 433. This restaurant offers various delicious and comforting meals and has an average rating of 4.4 out of 5 stars from 2,341 customers.

Locals also recommend Roma Sparita, another of the best restaurants in Rome. Roma Sparita is rated an average of 4.4 out of 5 stars by 2,073 customers.

After dinner, visit D’Angelo Caffè & Gastronomia - Bar Bistro Caffetteria Napoletana a Roma to enjoy a couple of drinks and relax. This bar is one of the best in Rome, with an average rating of 4.7 out of 5 stars by 1,054 customers.

You can also enjoy drinks at a popular bar like Cantina e Cucina. This bar is a great spot to meet new friends and celebrate your vacation. Cantina e Cucina has an average rating of 4.6 out of 5 stars by 7,907 customers.

Ai Tre Scalini is another bar locals often recommend. This bar offers a great variety of snacks and drinks and is rated an average of 4.4 out of 5 stars by 2,950 customers.

End your day by raising your glass in celebration of your incredible road trip adventure in Italy, and look forward to more great days to come!

You’ll stay in Ancona for 1 night.

One of the best places to explore in the city of Tivoli today is Hadrian's Villa. This excellent attraction is an archaeological site that has been rated an average of 4.6 out of 5 stars by 9,813 visitors. Each year, Hadrian's Villa attracts over 77,557 local and international travelers.

We also recommend you visit the amazing Villa d'Este, an outstanding giardino all'italiana, in the city of Tivoli. Around 25,000 travelers rated this attraction with 4.7 out of 5 stars. Given the incredible Villa d'Este's popularity, more than 139,855 people stop by Villa d'Este to explore it.

To experience the local culture, see more of Italy, and meet new people at the same time, we highly recommend you go on a tour. You’ll find many top-rated and popular tours in the city, offering unique experiences that will inspire you. On this tour, you can go on an epic adventure to some of the best places to visit in Italy. You also get to admire popular places of interest.

You could then travel to Santuario Madonna Delle Grazie for some unforgettable sightseeing experience. This popular attraction is a place of worship and is rated an average of 4.5 out of 5 stars by 343 visitors.

You’ll have your choice of the best hotels and places to stay in the city of Ancona.

After dinner, visit one of the top bars in the city of Ancona, Bàgolo Caffetteria. This popular bar is rated an average of 4.5 out of 5 stars by 423 customers.

You could also relax with a drink at a popular bar like Old Fashioned. This bar has an average rating of 4.4 out of 5 stars by 170 customers.

Mixer Bar is a popular bar that locals recommend in the city of Ancona. This bar is rated an average of 4.3 out of 5 stars by 123 customers.

Be sure to celebrate another day of your incredible road trip adventure through Italy with a toast!

Day 5 of your road trip in Italy is your departure day. This is your chance to catch one last glimpse of Ancona before saying goodbye to this wonderful destination. When you have time to explore the area before you make your way home, we recommend visiting some of the following attractions.

Passetto is an extraordinary attraction you could visit to enjoy your last day in Ancona. This top-tier point of interest and popular site of interest has an average rating of 4.5 out of 5 stars by 2,797 visitors.

Take a stroll along the main shopping streets of Ancona and find some souvenirs to remind you of your road trip in Italy.

You’ll then say farewell to Ancona. We wish you a pleasant journey home, with many wonderful memories of your unforgettable vacation in Italy!