6-Day Italy Road Trip from Ancona to Florence and Rome

Photo of the long staircase in the downtown of the beautiful ancient italian village.
Perfect travel plans
Everything included
Fully customizable

Description

Summary

Duration
6 days & 5 nights
Available
Jan. - Dec.
Hotel
5 nights included
Car rental
6 days included
Flights
Optional
Travel app
All vouchers, itinerary, & map

Description

Have the adventure of a lifetime with this 6-day road trip through Italy.

This incredible self-drive vacation package will take you through the best destinations in Italy. With this perfectly planned travel package, you will stay 2 nights in Ancona, 1 night in Florence, and 2 nights in Rome, experiencing the ultimate road trip in Italy. Your road trip will enable you to discover the country's most popular attractions and restaurants in Ancona, Florence, and Rome. We'll help you experience the best 6 days in Italy you can imagine so you can leave happy and inspired.

Upon arriving in Ancona, you'll collect the rental vehicle of your choice. From there, you'll be off to discover some of the most popular attractions in Italy, including the stunning Colosseum and Roman Forum.

You'll have an extensive selection of accommodations to choose from throughout your road trip. We've handpicked the best hotels and places to stay across the country, catering to all budgets. Whether you're in the mood for luxurious five-star hotels or cozy, budget-friendly accommodations, we've got you covered.

Your road trip will bring you close to the best attractions and most incredible sights in Italy. From the magnificent Piazza Navona to the breathtaking Pantheon and Trevi Fountain, your journey will take you on a thrilling adventure through some of the most iconic travel destinations in the country. Your discovery doesn't end there. Make sure to marvel at the remarkable St. Peter's Basilica and learn more about the unique Vatican Museums to truly immerse yourself in the local culture. As you hit the open road and drive through Ancona, Florence, and Rome, you'll also have plenty of opportunities to uncover hidden gems and experience the authentic charm of Italy. Whether you're exploring enchanting small towns, discovering scenic routes, or indulging in local cuisine, there's always something new and exciting to experience in Italy.

Add tours and tickets to each day of your trip to make the most of your time in Italy. You'll have the opportunity to choose from the best tours and activities that your travel destinations have to offer, meaning you'll never have a boring moment on your road trip through Italy.

Your travel plan itinerary also gives you multiple opportunities to look for souvenirs to memorialize your road trip in Italy.

You'll return home having experienced the very best of everything Italy has to offer. Each twist and turn of the journey adds a unique charm to your travel tales.

You can customize each day of your road trip vacation itinerary with flexible trip planning before and after booking. Enjoy the benefits of exploring all these great attractions at your own speed.

Your travel plan includes everything you need to experience the best of Italy. You'll be booked at the best hotels for 5 nights, with plenty of top-rated breakfast and restaurant options nearby. We'll provide you with the best car rental for 5 days during your self-drive road trip, including CDW insurance.

You'll have access to 24/7 travel support, a personal travel agent, and a step-by-step guide via our flexible mobile app. All taxes are included in your vacation package price. You can choose and add your flight preferences as needed. Make your vacation in Italy extra special by adding tours and tickets to each day of your itinerary.

The best services in Italy fill up quickly, so book your spot early. Select a date and start planning your self-drive road trip in Italy today!

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Included

Hotel, 5 nights
Rental car, 6 days
CDW Insurance
Step-by-step guide
Personal travel agent
24/7 travel support

Destinations

Marche - state in ItalyAncona / 2 nights
Florence Aerial View of Ponte Vecchio Bridge during Beautiful Sunny Day, ItalyFlorence / 1 night
Aerial panoramic cityscape of Rome, Italy, Europe. Roma is the capital of Italy. Cityscape of Rome in summer. Rome roofs view with ancient architecture in Italy. Rome / 2 nights

Map

Attractions

photo of trevi fountain at sunrise beautiful full view, Rome, Italy.Trevi Fountain
photo of Colosseum in Rome at sunrise, Italy, Europe.Colosseum
photo of view of Pantheon in the morning. Rome. Italy.Pantheon
photo of piazza navona in Rome, Italy. Rome navona square. Ancient stadium of Rome for athletic contests. Italy architecture and landmark. Piazza navona is one of the main attractions of Rome and Italy.Piazza navona
St. Peter's Basilica, Vatican CitySt Peter's Basilica
Vatican Museums, Vatican CityVatican Museums
photo of panoramic view of ancient ruins of a roman forum or foro romano at sunrise in rome, Italy. view from capitoline hill.Roman Forum
photo of piazza di spagna in rome, italy. Spanish steps in rome, Italy in the morning. One of the most famous squares in Rome, Italy. Rome architecture and landmark.Piazza di Spagna
photo of piazza del popolo (People's square) named after the church of santa maria del popolo in Rome, Italy.Piazza del Popolo
photo of View of statue of david on Piazzale Michelangelo at morning  in Florence, Italy.Piazzale Michelangelo
photo of Visit Italy, park Villa Borghese with boat and ducks.Villa Borghese
photo of holy angel castle, also known as hadrian mausoleum in the morning, Rome, Italy.Castel Sant'Angelo
Sistine ChapelSistine Chapel
photo of altare della patria, national monument to victor emmanuel II the first king of a unified Italy, located in Rome.Altare della Patria
church inside cave in Italy - Marche - the temple of Valadier church near Frasassi caves in Genga Ancona .Frasassi Caves
Sanctuary of the Holy House of Loreto, Loreto, Ancona, Marche, ItalySanctuary of the Holy House of Loreto
Mole Vanvitelliana also known as the lazaretto of AnconaLazzaretto of Ancona
Passetto beach with fishermans' boats and pope chair rock - Ancona - ItalyPassetto
Plebiscito square (or Pope square) with San Domenico Church in Ancona. Marche Region, Italy.Piazza del Plebiscito

Travel details

Travel dates
Jan 1 - Jan 6

Include flights?

Yes
No

Flights

Round trip
Economy
Round trip
Economy

Travelers

Rooms

1 traveler1 room
1 traveler1 room

Flights
Yes
No

Round trip
Economy
Round trip
Economy

Car
Yes
No

Car

Small car

Small car

Category
small car
Transmission
People
Large bags
Medium car

Medium car

Category
Medium
Transmission
People
Large bags
Premium car

Premium car

Category
premium car
Transmission
People
Large bags

Hotels

Personalize your itinerary

Day 1 – Ancona - arrival day

Day 1

Day 1 – Ancona - arrival day

  • Ancona - Arrival day
  • More
  • Passetto
  • More

Ancona has many popular destinations you can explore. You could visit attractions like the incredible Passetto. This attraction is a best-rated sightseeing destination and has an average rating of 4.5 out of 5 stars by 2,797 visitors.

Your stay promises to be a delightful continuation of your exploration, providing comfort and tranquility to recharge for the adventures that lie ahead.

When you’re ready for dinner, we recommend you try one of the best restaurants in the city of Ancona, Donegal Irish Pub. The restaurant is rated an average of 4.3 out of 5 stars by 1,118 customers.

Ancona also has several great bars that will fit all travel budgets. One of the best bars in the city of Ancona is Posa bar. This bar has an average rating of 4.5 out of 5 stars by 948 customers.

Enjoy toasting the start of your 6-day vacation in Italy!

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Experiences

Day 2 – Florence

Day 2

Day 2 – Florence

  • Ancona
  • Florence
  • More

Drive 338 km, 4 hours 21 min

  • Lazzaretto of Ancona
  • Sanctuary of the Holy House of Loreto
  • Frasassi Caves
  • More

Today, you'll hit the road once again, setting off on a journey towards the stunning city of Florence. You’ll stay in Florence for 1 night. But before you begin your drive, we recommend taking the time to explore some of Ancona’s must-see attractions and local hotspots.

If you’re curious to see more of Ancona, start your day with a visit to the amazing Lazzaretto of Ancona. This much-appreciated building and attraction is rated 4.4 out of 5 stars by 4,023 visitors.

You could also stop at another of the best local travel destinations in the area, the fascinating Sanctuary of the Holy House of Loreto. This church and spectacular attraction has an average rating of 4.8 out of 5 stars from 19,100 visitors.

We also recommend you spend some time at the popular Frasassi Caves to make the most of your road trip across Italy. The spectacular Frasassi Caves is a show cave that has been rated an average of 4.8 out of 5 stars by 20,728 visitors.

After soaking up all the sights and sounds that Ancona has to offer, you'll be ready to hit the open road and continue your unforgettable road trip towards the city of Florence. Florence offers plenty of options for top-rated hotels and other places to stay that fit all travel budgets.

After you’ve settled into your accommodation, we recommend a dinner at the popular Ristorante Paoli. This popular restaurant is one of the locals’ most recommended restaurants in the city, with ratings of 4.9 out of 5 stars in 6,031 reviews.

The remarkable Ristorante Oliviero 1962 is another top restaurant in Florence we recommend. This restaurant offers an unforgettable dining experience and is rated an average of 4.7 out of 5 stars by 1,046 customers.

If you would rather go somewhere else, the famous Il Vezzo is also an excellent choice. This well-loved restaurant is rated an average of 4.8 out of 5 stars by 862 customers.

After your meal, we recommend you drink at one of the best bars in Florence, the fantastic Manifattura. This bar has an average rating of 4.7 out of 5 stars by 509 customers.

To end your night the best way possible, we recommend going to the wonderful Ditta Artigianale. This bar offers a great variety of drinks and has been rated an average of 4.3 out of 5 stars by 1,877 customers.

Another bar with a great atmosphere is Archea Brewery. This bar is rated an average of 4.7 out of 5 stars by 723 customers, so don’t forget to check this one out as well!

Celebrate another amazing vacation day filled with adventure in Italy!

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Experiences

Day 3 – Florence, Vatican City, and Rome

Day 3

Day 3 – Florence, Vatican City, and Rome

  • Florence
  • Rome
  • More

Drive 288 km, 3 hours 47 min

  • Piazzale Michelangelo
  • Sistine Chapel
  • St Peter's Basilica
  • Vatican Museums
  • More

Rise and shine on day 3 of your road trip in Italy. Today, you'll wake up in Florence and embark on a scenic drive to Rome, where you'll stay at one of the best hotels for 2 nights. Seize the opportunity to explore spectacular attractions in Florence before you reach your end destination for the day.

It’s hard not to feel excited about visiting attractions in a destination as lovely as Florence. When you’re eager to explore the city and nearby areas, we recommend visiting some local favorites, such as the wonderful piazzale Michelangelo. This attraction is a square that has an average rating of 4.8 out of 5 stars from 77,744 visitors.

One of the most popular attractions you can visit is the remarkable Sistine Chapel. This attraction is a chapel that has an average rating of 4.7 out of 5 stars from 52,083 visitors.

If you want to explore more, visit the incredible St. Peter's Basilica. This major basilica and attraction has an average rating of 4.8 out of 5 stars from 131,043 reviews. This site welcomes approximately 11,000,000 yearly visitors.

Another site you could visit today is the top-rated Vatican Museums. This art museum and travel destination is rated an average of 4.6 out of 5 stars by 133,310 visitors. Approximately 1,612,530 people visit this attraction every year.

We recommend you end the day with a dinner at a popular restaurant near your accommodation, like Cantina e Cucina. This restaurant offers various delicious and comforting meals and has an average rating of 4.6 out of 5 stars from 7,907 customers.

Locals also recommend Ai Tre Scalini, another of the best restaurants in Rome. Ai Tre Scalini is rated an average of 4.4 out of 5 stars by 2,950 customers.

If you feel like having something else, check out the menu at 433. This restaurant has been rated an average of 4.4 out of 5 stars by 2,341 customers and is a great place to enjoy a lovely meal.

After dinner, visit D’Angelo Caffè & Gastronomia - Bar Bistro Caffetteria Napoletana a Roma to enjoy a couple of drinks and relax. This bar is one of the best in Rome, with an average rating of 4.7 out of 5 stars by 1,054 customers.

This bar is a great spot to meet new friends and celebrate your vacation.

End your day by raising your glass in celebration of your incredible road trip adventure in Italy, and look forward to more great days to come!

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Experiences

Day 4 – Rome

Day 4

Day 4 – Rome

  • Rome
  • More

Drive 13 km, 54 min

  • Colosseum
  • Roman Forum
  • Castel Sant'Angelo
  • Piazza navona
  • Pantheon
  • More

On day 4 of your road trip across Italy, you’ll have the perfect day exploring the wonderful city of Ancona. You’ll stay in Ancona for 1 night, meaning you have plenty of time to discover the best things to see and do in the area.

We recommend you stay at the Relais Castrum Boccea, one of the best 4-star hotels in the city of Ancona. This hotel has an average rating of 4 out of 5 stars by 630 guests.

The best luxury hotel option in the city of Ancona is the 5-star Hotel Caravita. The hotel is rated an average of 4.4 out of 5 stars by 262 guests.

One of the best hotels we recommend in the city of Ancona is the 3-star Hotel Sirenetta. This 3-star hotel has an average rating of 4.1 out of 5 stars by 4,089 guests.

Our flexible booking system will automatically provide you with the best alternatives if these hotels are not available.

You'll have easy access to popular travel destinations in the city of Ancona, like the outstanding Colosseum. This attraction has an average rating of 4.7 out of 5 stars by 328,821 visitors and gathers around 7,400,000 every year.

Roman Forum is another popular attraction you could visit in the city of Ancona. This incredible attraction is a square and has been rated an average of 4.7 out of 5 stars by 114,450 visitors.

One of the best attractions you could visit in the city of Ancona is the extraordinary Castel Sant'Angelo. This museum gets more than 918,591 visitors on an annual basis and is rated an average of 4.7 out of 5 stars in 72,431 reviews.

As the day moves along, one attraction you’ll probably want to visit is the incredible Piazza Navona. Around 158,771 visitors have given this square an average rating of 4.7 out of 5 stars.

Today you'll also have the opportunity to spend some time at the fantastic Pantheon. Pantheon is a popular roman temple, rated an average of 4.8 out of 5 stars by 189,682 travelers. Around 30,000,000 people visit this roman temple each year.

Come to Ancona prepared by adding some tours and tickets to your vacation package. Book a popular and budget-friendly activity you can do on this day in Ancona.

After a day of exploring, try one of the best restaurants in the city of Ancona.

We recommend you eat at a delicious restaurant that locals enjoy, like Roma Sparita, after your day of exploring the city of Ancona. This excellent restaurant has an average rating of 4.4 out of 5 stars by 2,073 customers.

Ristorante Amedeo is another of the best restaurants in the city of Ancona. This restaurant is rated an average of 4.3 out of 5 stars by 1,798 customers.

Locals recommend VinAllegro, one of the best bars in the city of Ancona, for a refreshing evening drink to finish your day. This bar is rated an average of 4.3 out of 5 stars by 1,167 customers.

Alternatively, you could choose another of the most popular bars in the city of Ancona, Ristorante Tema. This bar has an average rating of 4.4 out of 5 stars by 939 customers.

Bar Tornatora Rome is also one of the best bars in the city of Ancona. This bar is rated an average of 4.3 out of 5 stars by 952 customers.

It's a perfect place to relax and enjoy another amazing evening in Italy.

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Experiences

Day 5 – Rome and Ancona

Day 5

Day 5 – Rome and Ancona

  • Rome
  • Ancona
  • More

Drive 319 km, 4 hours 12 min

  • Altare della Patria
  • Trevi Fountain
  • Piazza di Spagna
  • Piazza del Popolo
  • Villa Borghese
  • More

Day 5 of your road trip through Italy gives you the opportunity to experience two places in one day. You'll start your day with some exploring in the city of Ancona and end it at a top-rated hotel in the city of Ancona. You will stay in Ancona for 1 night. Have a hearty breakfast and get excited for a wonderful day ahead!

One of the best places to visit today in Ancona is the amazing Altare della Patria. As such, over 1,683,070 people visit Altare della Patria yearly. This attraction is an architectural structure that is rated an average of 4.8 out of 5 stars by 49,843 visitors.

You could also stop at the incredible sculpture, Trevi Fountain. With an average rating of 4.8 out of 5 stars by 343,494 visitors, this attraction is one of the top sights in the area.

Another unforgettable travel destination in the Ancona is the outstanding Piazza di Spagna. This popular square and travel destination has an average rating of 4.7 out of 5 stars by 113,658 visitors. Approximately 1,683,070 travelers come to Ancona every year to see the stunning Altare della Patria with their own eyes.

The spectacular piazza del Popolo is another popular attraction you can visit today. This fascinating square and attraction has an average rating of 4.6 out of 5 stars from 89,807 visitors.

If you’re keen to explore even more, then consider a visit to the fantastic Villa Borghese. This attraction is a popular urban zone of rome that has an average rating of 4.6 out of 5 stars from 69,749 visitors.

You can make the most of your new day in Ancona by joining activities and tours that let you discover what else the city has in store for you. There are many top-rated experiences you can include in your travel plan to add flavor to your road trip in Italy. Browse all of your options and reserve your slot before it's too late.

At the end of the day, you will drive to the city of Ancona, where you will access the best hotels and places to stay.

After dinner, visit Bàgolo Caffetteria, which is considered one of the best bars in the city of Ancona. This bar is rated an average of 4.5 out of 5 stars by 423 customers.

You can also enjoy drinks at a popular bar like Old Fashioned. This bar has an average rating of 4.4 out of 5 stars by 170 customers.

Alternatively, Mixer Bar is one of the best bars that locals recommend in the city of Ancona. This bar is rated an average of 4.3 out of 5 stars by 123 customers.

Raise your glass in celebration of your incredible road trip adventure through Italy!

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Experiences

Day 6 – Ancona - departure day

Day 6

Day 6 – Ancona - departure day

  • Ancona - Departure day
  • More
  • Piazza del Plebiscito
  • More

Day 6 of your road trip in Italy is your departure day. This is your chance to catch one last glimpse of Ancona before saying goodbye to this wonderful destination. When you have time to explore the area before you make your way home, we recommend visiting some of the following attractions.

Piazza del Plebiscito is an extraordinary attraction you could visit to enjoy your last day in Ancona. This square and popular site of interest has an average rating of 4.4 out of 5 stars by 2,631 visitors.

Take a stroll along the main shopping streets of Ancona and find some souvenirs to remind you of your road trip in Italy.

You could then enjoy your last meal in the city of Ancona at Mixer Bar before you travel home. This popular restaurant is rated an average of 4.3 out of 5 stars by 123 customers.

You’ll then say farewell to Ancona. We wish you a pleasant journey home, with many wonderful memories of your unforgettable vacation in Italy!

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Experiences

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