6-Day Italy Road Trip from Florence to Venice, Siena, and Rome and surrounding area

On day 2 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 1 destination, Florence. When you’re not sightseeing, take time to relax at your selected hotel in Venice, where you’ll be staying for 1 night.

Drop by the renowned Abbazia Di San Miniato Al Monte. This popular church has been rated an average of 4.8 out of 5 stars by 4,435 visitors.

Another unforgettable place to experience is Piazzale Michelangelo. Rated 4.8 out of 5 stars by 77,744 visitors, this square deserves a spot on today's sightseeing itinerary.

We also recommend a visit to Porta Romana. This sightseeing destination has been rated an average of 4.4 out of 5 stars in 4,489 reviews.

Another favorite attraction in the area is Parco Delle Cascine. This park and popular place of interest enjoys a rating of 4.3 out of 5 stars from 14,875 local and international travelers.

When you’re done exploring for the day, you’ll drive to Venice, where you'll have a hotel waiting for you. Check in and spend some time relaxing before you head out to explore the city.

As dinnertime approaches, it's time to head out for a bite to eat in Venice. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Get ready for an unforgettable culinary journey in Venice by reserving a table at Local. Renowned as a 1-star Michelin restaurant, it offers an exceptional contemporary menu. For a different taste experience, head to Wistèria, recognized for its delicious contemporary, and venetian dishes. This 1-star Michelin restaurant consistently impresses guests, ensuring a memorable addition to your holiday. Looking for another option? Make sure to visit Quadri, a local favorite known for its delightful modern cuisine in Venice. Nestled in the heart of the city, this restaurant with 1 Michelin star is an ideal choice for discerning modern foodies seeking culinary excellence.

Continue your evening by exploring the vibrant nightlife scene at Al Parlamento, a prime destination for a thrilling night out. Also, don’t forget to check out Adagio, a bar that offers unique local touches. Likewise, Il Mercante provides an excellent alternative for a fun evening.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in in Italy.

Dive into day 3 of your remarkable road trip in Italy. Today you will explore Venice, and Verona, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Siena. You’ll stay here for 1 night.

Begin your sightseeing with a visit to Bridge Of Sighs. This extraordinary footbridge is rated an average of 4.6 out of 5 stars by 18,223 visitors.

Next, make your way to Piazza San Marco. This top attraction is a square with an average rating of 4.7 out of 5 stars by 152,982 visitors.

We also recommend a visit to Rialto Bridge. This stone bridge is rated 4.7 out of 5 stars by 141,666 travelers.

When you’ve had your share of Venice, prepare for your next destination. Admire the views and listen to some good music as you drive in the direction of Verona. Your travel time is around 1 hour 24 min.

Your sightseeing of the day begins at Verona Arena, a remarkable opera house where it’s easy to get lost in exploration. This top attraction is rated an average of 4.7 out of 5 stars in 123,818 reviews. Each year, this popular place of interest welcomes approximately 195,540 visitors.

At the end of the day, you will drive to Siena, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Siena. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Enjoy a lovely meal at Antica Trattoria Papei, a top-rated place to have dinner tonight. Alternatively, if your taste buds call for something different, Osteria Quattro Venti is another top choice with a popular menu. You could also check for a table at Osteria da Divo. As an establishment that gains consistently high praises from customers, it’s an ideal choice in Siena tonight.

Explore the vibrant nightlife at Meet Life Cafè after your meal, a hub for lively evenings and memorable moments. Or, head to Maudit Pub for a great selection of flavorful drinks and a charming setting. Furthermore, Bar Impero Siena is perfect for those looking to extend their night with a touch of local flavor.

Get a good night's sleep and look forward to another great day on the road in Italy!

Experience an unparalleled adventure on day 4 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 2 vibrant destinations - Siena, and Vatican City. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Rome. You will spend 1 night here for some well-deserved relaxation.

Seize the day by visiting some of the best attractions in the area, like Piazza Del Campo. This extraordinary square has an average rating of 4.8 out of 5 stars from 64,175 visitors.

Once you're ready to continue your road trip, it's time to buckle up and drive towards Vatican City, eagerly anticipating your arrival in Vatican City. This drive usually takes around 2 hours 39 min, without any stops or traffic disruptions.

Make Sistine Chapel one of your first sightseeing stops in Vatican City. Rated an average of 4.7 out of 5 stars by 52,083 travelers, a visit to this local attraction makes for a great introduction to the area.

St. Peter's Basilica is a worthwhile attraction you can visit next. This major basilica is a valued place of interest in the area, with an average rating of 4.8 out of 5 stars from 131,043 reviews. Up to 11,000,000 travelers visit this site every year to make their time in Vatican City special.

Today is also the perfect opportunity to drop by Vatican Museums. This art museum has been rated an average of 4.6 out of 5 stars by 133,310 visitors. Up to 1,612,530 people travel to this site annually.

After soaking up all the sights of today's itinerary, you'll be ready to hit the road in the direction of your accommodation in Rome. Rome offers plenty of top-rated hotels and other places to stay on any travel budget. Take some time to relax before you head out to explore.

After a day of adventure, treat yourself to an exquisite dinner at one of Rome's best restaurants.

Dive into a culinary adventure like no other in Rome by booking a table at La Pergola. This popular restaurant holds 3 Michelin star and offers an exceptional menu of mediterranean, and contemporary cuisine. For another culinary dining option, venture to Il Pagliaccio, celebrated for its delectable creative, and innovative menu. This acclaimed 2-star Michelin-recipient consistently leaves guests satisfied, ensuring an essential addition to your holiday itinerary. Seeking an alternative? Discover Enoteca La Torre, a top local restaurant known for its tantalizing mediterranean, and creative menu. With a 2-star Michelin recognition, it promises an exceptional dining experience not to be missed.

After your meal, keep the night alive at a bar like La Botticella Of Poggi Giovanni, known for its lively atmosphere. Sant' Eustachio Caffè is another top recommendation that provides the perfect setting with well-crafted drinks and a welcoming ambiance. Similarly, Caffè Portofino offers an excellent atmosphere for those looking to amp up the evening.

Raise your glass to another unforgettable day in Italy!

Embark on another extraordinary experience on day 5 of your road trip in Italy. Today, you will make 1 stop and experience some of the highlights of Rome. At the end of the day, you will enjoy the comforts of a top-rated hotel in Florence, which will be your home away from home for 1 night.

Kick off the day at Roman Forum, a top pick for today’s sightseeing. This square is rated an average of 4.7 out of 5 stars in 114,450 reviews.

Today is also your chance to visit Colosseum. Colosseum is a roman amphitheatre with an average rating of 4.7 out of 5 stars from 328,821 reviews. Attracting more than 7,400,000 yearly visitors, this place of interest is an attraction you don’t want to miss out on.

Pantheon is another top attraction we highly recommend you visit today. This roman temple is rated an average of 4.8 out of 5 stars by 189,682 visitors. In a single year, this roman temple hosts approximately 30,000,000 visitors.

Beyond the attractions mentioned above, you also have the opportunity to visit Piazza Navona. This square is rated an average of 4.7 out of 5 stars by 158,771 visitors.

Lastly, don’t miss out on Trevi Fountain, a famous sculpture in Rome. This attraction is rated an average of 4.8 out of 5 stars by 343,494 travelers.

When you’re done exploring for the day, you’ll drive to Florence, where you'll have a hotel waiting for you. Check in and spend some time relaxing before you head out to explore the city.

Indulge in a memorable dining experience at one of Florence's most popular restaurants, and connect with friendly locals for an authentic adventure.

Enjoy an outstanding dining experience at Enoteca Pinchiorri, a 3-star Michelin restaurant offering an exceptional italian contemporary menu. If you are in the mood for trying an alternative dining experience, consider visiting the nearby 2-star Michelin-awardee, Santa Elisabetta, known for its delicious creative, and mediterranean cuisine. Another highly-recommended restaurant in Florence is Gucci Osteria da Massimo Bottura, a renowned restaurant with a 1-star Guide Michelin recognition, known for its delicious italian contemporary, and international menu.

Raise your glass and celebrate another amazing day of your road trip in Italy!