6-Day Italy Self-Drive Road Trip With Itinerary from Genoa to Florence

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Escape the ordinary with this exciting 6-day road trip through Italy. Explore the diverse landscapes, lively cities, and beyond. Pack your bags, hit the road, and prepare for an unforgettable journey!

This perfectly planned road trip itinerary in Italy takes you through some of the best places to see in the country. You will spend 4 nights in Genoa and 1 night in Florence. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Italy. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have got you covered.

Upon arriving in Genoa, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Italy on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Italy. Ponte Vecchio and Leaning Tower Of Pisa are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Piazza Del Duomo, Pisa, learn more about the unique Cathedral Of Santa Maria Del Fiore, and immerse yourself in the vibrant atmosphere of Piazza Della Signoria.

As you hit the open road and drive through Genoa, Riomaggiore, Manarola, Corniglia, Florence, Pisa, and Lucca, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Italy. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Italy.

Throughout your road trip in Italy, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Italy.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodation, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Italy fill up quickly, so book your spot early. Select a date and start planning your road trip in Italy today!

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Itinerary summary

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Days
Destination
Attractions
Overnight
Day
City & Overnight
Attractions
Aquarium of Genoa
Piazza della VittoriaDoge's Palacepiazza De FerrariVia GaribaldiPalazzo PodestàLighthouse of Genoa
RiomaggioreManarola Overlook ViewpointCinque Terre National ParkScalinata Lardarina
Basilica of Santa Croce in FlorenceUffizi GalleryPonte VecchioPiazza della RepubblicaCathedral of Santa Maria del Fiorepiazza della Signoria
Pisa CathedralPiazza del Duomo, PisaLeaning Tower of PisaWalls of LuccaPorta San Pietro
porto antico

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Day 1

Day 1

  • Genoa - Arrival day
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  • Aquarium of Genoa
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Say hello to Genoa! Your exciting road trip through Italy is just about to start. Navigating the top places to see in the region is a breeze with a car. The rental vehicle of your choice will be ready for pickup upon your arrival in the city. You will stay in Genoa for 3 nights before you continue your adventure!

Genoa is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Aquarium Of Genoa, or just taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

As afternoon approaches, head to your chosen hotel in Genoa. Check-in typically starts around 2 to 4 PM at hotels in Italy. We recommend staying at a hotel in a central location for easy access to the best attractions, restaurants, and bars in the city.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Genoa, it's often a good idea to reserve a table in advance.

Treat yourself to a delicious dinner at 7 Sensi cucina decontaminata, an excellent option for tonight's dining. Looking for something different? Alla Lunga Ristorante offers a tantalizing alternative with its diverse menu. And don’t miss Grand Hotel Savoia. With its reputation for pleasing customers, it’s a fantastic choice for tonight in Genoa.

Explore the vibrant nightlife at Scurreria Beer & Bagel after your meal, a hub for lively evenings and memorable moments. Or, head to La Lepre for a great selection of flavorful drinks and a charming setting. Furthermore, Bar Pisacane Iii is perfect for those looking to extend their night with a touch of local flavor.

Raise a toast to the start of your 6-day road trip in Italy!

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Day 2

Day 2

  • Genoa
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Drive 17 km, 1 hour 15 min

  • Piazza della Vittoria
  • Doge's Palace
  • piazza De Ferrari
  • Via Garibaldi
  • Palazzo Podestà
  • Lighthouse of Genoa
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Day 2 of your road trip will take you to the best attractions Genoa has to offer. Cherish the 2 nights you have left in Genoa by discovering the best things there are to see and do in the city.

Get ready for a day filled with family-friendly attractions, picturesque spots, and history-rich sites in the charming city of Genoa. Your adventure starts at Piazza Della Vittoria, an intriguing local hot spot. Another notable attraction to explore is Doge's Palace. This up-and-coming museum is known for its photogenic appeal.

After soaking in the highlights of these sights, take some time to wander Genoa's streets and immerse yourself in the local atmosphere. When you're ready to continue your sightseeing adventure, head to Piazza De Ferrari. This grand public square offers a fascinating experience that many visitors find memorable. Via Garibaldi is also worth visiting, along with Palazzo Podestà. These standout landmarks offer unique experiences that add to the day’s enjoyment. End your day at Lighthouse Of Genoa. This increasingly popular lighthouse provides a fitting finale to your sightseeing.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

As dinnertime approaches, it's time to head out for a bite to eat in Genoa. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Treat yourself to a delightful dinner at Zeffirino, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Trattoria Vegia Zena? It's another excellent option with a diverse menu. Consider reserving a table at Trattoria delle Grazie as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Genoa.

Head back to your accommodation in Genoa and get some rest in preparation for another magical day of your road trip in Italy!

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Day 3

Day 3

  • Genoa
  • More

Drive 250 km, 4 hours 44 min

  • Riomaggiore
  • Manarola Overlook Viewpoint
  • Cinque Terre National Park
  • Scalinata Lardarina
  • More

Greet day 3 of your road trip in Italy with a smile and start your day with a hearty breakfast. You will return to Genoa for your remaining 1 night in the city later today, but first, it’s time for some exploring! On the agenda for this day, you’ll find only the best things to see and do in Riomaggiore, Manarola, and Corniglia.

Just a short distance away you'll find your next stop, Manarola Overlook Viewpoint, a romantic observation deck that draws visitors from far and near.

Continue your journey to Cinque Terre National Park, one of the village’s most popular spots that you shouldn’t miss. Another great site to visit is the beloved Scalinata Lardarina.

When you’re done exploring for the day, you’ll return to Genoa and your accommodation.

After a day of adventure, treat yourself to an exquisite dinner at one of Genoa's best restaurants.

Make sure to reserve a table at Osteria Sant'Ilario, an iconic dining spot in Genoa. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of La Cialtroneria, a popular restaurant in Genoa. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Manhattan Bar, a hidden gem nestled in Genoa. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

As the sun sets on another day of adventure, rest up and recharge for the next leg of your road trip in Italy.

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Day 4

Day 4

  • Genoa
  • Florence
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Drive 236 km, 3 hours 34 min

  • Basilica of Santa Croce in Florence
  • Uffizi Gallery
  • Ponte Vecchio
  • Piazza della Repubblica
  • Cathedral of Santa Maria del Fiore
  • piazza della Signoria
  • More

Experience an unparalleled adventure on day 4 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 1 vibrant destinations - Florence. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Florence. You will spend 1 night here for some well-deserved relaxation.

Get ready for a day filled with fun adventures, photo-friendly spots, and historic treasures in the charming city of Genoa. Your adventure starts at Basilica Of Santa Croce In Florence, a captivating local hot spot. Another notable attraction to explore is Uffizi Gallery. This spectacular art gallery is known for its culturally significant appeal.

After soaking in the highlights of these sights, take some time to wander Genoa's streets and immerse yourself in the local atmosphere. When you're ready to continue your sightseeing adventure, head to Ponte Vecchio. This romantic historical landmark offers a fascinating experience that many visitors find memorable. Piazza Della Repubblica is also worth visiting, along with Cathedral Of Santa Maria Del Fiore. These standout landmarks offer unique experiences that add to the day’s enjoyment. End your day at Piazza Della Signoria. This astonishing public square provides a fitting finale to your sightseeing.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Florence. Florence offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Florence. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Don’t miss out on dining at Ristorante Oliviero 1962, a top-rated dining destination in Florence. If you're in the mood to try something new, consider Di Poneta Novoli, another top spot with a mouthwatering menu. You might also want to secure a reservation at Caffe San Firenze. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Florence this evening.

Keep the evening going at Manifattura, a great choice for enjoying the after-dinner hours with a drink. You could also go to Se·sto On Arno Rooftop Bar, which offers a similarly pleasant setting and great drinks. Another option is Il Vinile, which provides an inviting environment for unwinding after a busy day out.

As the sun sets on another day of adventure, rest up and recharge for the next leg of your road trip in Italy.

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Day 5

Day 5

  • Florence
  • Genoa
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Drive 262 km, 3 hours 43 min

  • Pisa Cathedral
  • Piazza del Duomo, Pisa
  • Leaning Tower of Pisa
  • Walls of Lucca
  • Porta San Pietro
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Embark on another extraordinary experience on day 5 of your road trip in Italy. Today, you will make 2 stops and experience some of the highlights of Pisa and Lucca. At the end of the day, you will enjoy the comforts of a top-rated hotel in Genoa, which will be your home away from home for 1 night.

Discover a day packed with family-friendly attractions, scenic views, and photo-friendly spots in Florence. Begin your sightseeing with Pisa Cathedral. This locally appreciated church is one of the top attractions in the city. Proceed to Piazza Del Duomo, Pisa, another must-visit attraction.

As you wander through the inviting streets of Florence, soak in the lively ambiance and take the opportunity to snap some photos. Next, head to Leaning Tower Of Pisa. This world-famous monument is a traveler-favorite. Not far away, you’ll find Mura Di Lucca, another key site on your sightseeing itinerary. Porta San Pietro is yet another highly recommended place to visit nearby, offering plenty to discover for curious travelers.

When you’re done exploring for the day, you’ll drive to your hotel in Genoa. Check in and spend some time relaxing before you head out to tour the city.

As you explore more of Genoa, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Have a fantastic dining experience at Vivarelli, a highly recommended choice for tonight's dinner. If you're looking to mix things up, Trattoria Ugo offers an enticing alternative with its varied menu. Additionally, TAZZE PAZZE Specialty Coffee is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Genoa.

Head back to your accommodation in Genoa and get some rest in preparation for another magical day of your road trip in Italy!

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Day 6

Day 6

  • Genoa - Departure day
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  • porto antico
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Day 6 of your road trip in Italy is your departure day. This is your chance to catch a last glimpse of Genoa before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, we recommend visiting Porto Antico, a visually striking public square before you head out.

Maximize your last day in Italy and go on a shopping spree in Genoa’s shopping center, the lively Porto Antico. Browse for souvenirs to remind you of your wonderful journey in Italy.

Before you conclude your road trip in Italy, drop by another restaurant for a last chance at a memorable dining experience in Genoa.

If you're eager to try something different, consider Il Marin, another top spot with a tantalizing menu.

You’ll then say farewell to Genoa. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Italy!

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