6-Day Italy Self-Drive Road Trip With Itinerary from Genoa to Florence

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Experience the freedom of the open road in Italy as you embark on an unforgettable 6-day road trip! This experience caters to every traveler, featuring destinations like Genoa, Riomaggiore, Manarola, Corniglia, Florence, Pisa, and Lucca.

This perfectly planned road trip itinerary in Italy takes you through some of the best places to see in the country. You will spend 4 nights in Genoa and 1 night in Florence. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Italy. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have got you covered.

Upon arriving in Genoa, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Italy on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Italy. Ponte Vecchio and Leaning Tower Of Pisa are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Piazza Del Duomo, Pisa, learn more about the unique Cathedral Of Santa Maria Del Fiore, and immerse yourself in the vibrant atmosphere of Piazza Della Signoria.

As you hit the open road and drive through Genoa, Riomaggiore, Manarola, Corniglia, Florence, Pisa, and Lucca, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Italy. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Italy.

Throughout your road trip in Italy, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Italy.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodation, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Italy fill up quickly, so book your spot early. Select a date and start planning your road trip in Italy today!

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Driver’s age is 30 - 65
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Itinerary summary

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Days
Destination
Attractions
Overnight
Day
City & Overnight
Attractions
Aquarium of Genoa
Piazza della VittoriaDoge's Palacepiazza De FerrariVia GaribaldiPalazzo PodestàLighthouse of Genoa
RiomaggioreManarola Overlook ViewpointCinque Terre National ParkScalinata Lardarina
Basilica of Santa Croce in FlorenceUffizi GalleryPonte VecchioPiazza della RepubblicaCathedral of Santa Maria del Fiorepiazza della Signoria
Pisa CathedralPiazza del Duomo, PisaLeaning Tower of PisaWalls of LuccaPorta San Pietro
porto antico

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Day 1

Day 1

  • Genoa - Arrival day
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  • Aquarium of Genoa
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Your road trip adventure in Italy begins as soon as you reach Genoa and pick up your car. You’ll stay in Genoa for 3 nights and explore the best things to see and do, sample the local cuisine, and choose from a curated selection of the best hotels and places to stay in the city.

Genoa is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Aquarium Of Genoa, or just taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

As afternoon approaches, head to your chosen hotel in Genoa. Check-in typically starts around 2 to 4 PM at hotels in Italy. We recommend staying at a hotel in a central location for easy access to the best attractions, restaurants, and bars in the city.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Genoa, it's often a good idea to reserve a table in advance.

Treat yourself to a delicious dinner at 7 Sensi cucina decontaminata, an excellent option for tonight's dining. Looking for something different? Alla Lunga Ristorante offers a tantalizing alternative with its diverse menu. And don’t miss Grand Hotel Savoia. With its reputation for pleasing customers, it’s a fantastic choice for tonight in Genoa.

Continue your lively evening at Scurreria Beer & Bagel, a perfect place for winding down or revving up the night, depending on which mood you’re in. La Lepre is another excellent bar that offers a great selection of drinks to suit any mood. If you prefer to go somewhere else, Bar Pisacane Iii ensures a night out tailored to your taste.

Raise a toast to the start of your 6-day road trip in Italy!

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Day 2

Day 2

  • Genoa
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Drive 17 km, 1 hour 15 min

  • Piazza della Vittoria
  • Doge's Palace
  • piazza De Ferrari
  • Via Garibaldi
  • Palazzo Podestà
  • Lighthouse of Genoa
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On day 2 of your road trip, you will have an entire day to explore Genoa. You’ll stay in Genoa for 2 nights and discover all the best things to see and do in the area.

A blend of family-friendly attractions, photo-friendly spots, and history-rich sites await you in Genoa on today’s itinerary. First up is the often recommended public square, Piazza Della Vittoria. Afterward, continue to Doge's Palace, a museum every traveler should visit.

As you explore Genoa’s charming streets, take in the lively atmosphere and get to know the character of the city. Next, make your way to Piazza De Ferrari. This interesting public square is an essential stop. Following that, head to Via Garibaldi, another must-visit site that will enhance your experience. Don’t forget to stop by Palazzo Podestà, a curiosity-inducing palace in the city. Finally, end your day with a visit to Lighthouse Of Genoa, a historic lighthouse that offers the perfect conclusion to your sightseeing of the day.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

As you explore more of Genoa, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Enjoy a delicious meal at Zeffirino, a highly-rated dining destination in Genoa. If you're eager to try something different, consider Trattoria Vegia Zena, another top spot with a tantalizing menu. You might also want to secure a reservation at Trattoria delle Grazie. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Genoa this evening.

Savor another day of unforgettable experiences in Italy!

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Day 3

Day 3

  • Genoa
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Drive 250 km, 4 hours 44 min

  • Riomaggiore
  • Manarola Overlook Viewpoint
  • Cinque Terre National Park
  • Scalinata Lardarina
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Wake up to day 3 of your extraordinary road trip in Italy. With 1 night left in Genoa, we encourage you to seize the day and discover the unexplored beauty of the city’s surroundings!

Start your day with a visit to Riomaggiore. This up-and-coming sightseeing destination is a must-visit in the village. When you’re ready for your next discovery, continue to Manarola Overlook Viewpoint, which may be one of the most mesmerizing places you will experience today.

One of the best things about exploring Genoa on a self-guided tour is that you set the pace. There’s plenty of time for detours and discovering hidden gems. When you’re ready for your next stop, make your way to Cinque Terre National Park, an interesting national park in the village. If you’re up for more discoveries, don’t forget to reserve some time for Scalinata Lardarina.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Genoa.

After a day of adventure, treat yourself to an exquisite dinner at one of Genoa's best restaurants.

Make sure to reserve a table at Osteria Sant'Ilario, an iconic dining spot in Genoa. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of La Cialtroneria, a popular restaurant in Genoa. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Manhattan Bar, a hidden gem nestled in Genoa. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Get a good night's sleep and look forward to another great day on the road in Italy!

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Day 4

Day 4

  • Genoa
  • Florence
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Drive 236 km, 3 hours 34 min

  • Basilica of Santa Croce in Florence
  • Uffizi Gallery
  • Ponte Vecchio
  • Piazza della Repubblica
  • Cathedral of Santa Maria del Fiore
  • piazza della Signoria
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On day 4 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 1 destination, Florence. When you’re not sightseeing, take time to relax at your selected hotel in Florence, where you’ll be staying for 1 night.

Genoa is brimming with adventures. Today’s wonderful stops include a church, an art gallery, a historical landmark, a public square and much more! Begin your sightseeing adventure at the notable Basilica Of Santa Croce In Florence and allow yourself time to explore. Just a short distance away you'll find your next stop, Uffizi Gallery, a picture-perfect art gallery that draws visitors from far and near.

Continue your journey to Ponte Vecchio, one of the city’s most world-famous spots that you shouldn’t miss. Another great site to visit is the notable Piazza Della Repubblica. When you're finished at the public square, Cathedral Of Santa Maria Del Fiore awaits your visit. This church is a symbolic highlight on today's itinerary. Last up is a public square - the spectacular Piazza Della Signoria.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Florence. Florence offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Florence. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Enjoy a delicious meal at Ristorante Oliviero 1962, a highly-rated dining destination in Florence. If you're eager to try something different, consider Di Poneta Novoli, another top spot with a tantalizing menu. You might also want to secure a reservation at Caffe San Firenze. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Florence this evening.

Keep the evening going at Manifattura, a great choice for enjoying the after-dinner hours with a drink. You could also go to Se·sto On Arno Rooftop Bar, which offers a similarly pleasant setting and great drinks. Another option is Il Vinile, which provides an inviting environment for unwinding after a busy day out.

Celebrate another amazing day of your road trip adventure in Italy!

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Day 5

Day 5

  • Florence
  • Genoa
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Drive 262 km, 3 hours 43 min

  • Pisa Cathedral
  • Piazza del Duomo, Pisa
  • Leaning Tower of Pisa
  • Walls of Lucca
  • Porta San Pietro
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Embark on another extraordinary experience on day 5 of your road trip in Italy. Today, you will make 2 stops and experience some of the highlights of Pisa and Lucca. At the end of the day, you will enjoy the comforts of a top-rated hotel in Genoa, which will be your home away from home for 1 night.

Discover a day packed with family-friendly attractions, breathtaking views, and picturesque spots in Florence. Begin your sightseeing with Pisa Cathedral. This beloved church is one of the top attractions in the city. Proceed to Piazza Del Duomo, Pisa, another must-visit attraction.

As you wander through the inviting streets of Florence, soak in the lively ambiance and take the opportunity to snap some photos. Next, head to Leaning Tower Of Pisa. This iconic monument is a traveler-favorite. Not far away, you’ll find Mura Di Lucca, another key site on your sightseeing itinerary. Porta San Pietro is yet another highly recommended place to visit nearby, offering plenty to discover for curious travelers.

At the end of the day, you will drive to Genoa, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As dinnertime approaches, it's time to head out for a bite to eat in Genoa. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Treat yourself to a delightful dinner at Vivarelli, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Trattoria Ugo? It's another excellent option with a diverse menu. Consider reserving a table at TAZZE PAZZE Specialty Coffee as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Genoa.

Raise your glass to another unforgettable day in Italy!

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Day 6

Day 6

  • Genoa - Departure day
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  • porto antico
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Day 6 of your road trip in Italy is your departure day. This is your chance to catch a last glimpse of Genoa before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, we recommend visiting Porto Antico, a history-steeped public square before you head out.

Explore local shops for souvenirs to remember your trip or find unique gifts for loved ones.

Before you conclude your road trip in Italy, drop by another restaurant for a last chance at a memorable dining experience in Genoa.

You’ll then say farewell to Genoa. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Italy!

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