6-Day Italy Road Trip from Milan to Genoa, and Florence

Your road trip adventure in Italy begins as soon as you reach Milan and pick up your car. You’ll stay in Milan for 1 night and explore the best things to see and do, sample the local cuisine, and choose from a curated selection of the best hotels and places to stay in the city.

Milan is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Arch Of Peace or taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

Find your way to your hotel in Milan. We recommend choosing a hotel in a central location for easy exploring. Check-in typically starts between 2 and 4 PM at hotels in Italy. Settle in and make plans for the evening.

As dinnertime approaches, it's time to head out for a bite to eat in Milan. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Dine in style at Contraste, a top recommendation for dinner tonight. Or, for a change of pace, Radisson Blu Hotel Milan boasts a menu that's sure to impress. Also, be sure to check out Bice Restaurant. Known as a local hotspot, it’s a great choice for tonight in Milan.

Continue your evening by exploring the vibrant nightlife scene at Nottingham Forest, a prime destination for a thrilling night out. Also, don’t forget to check out Armani/bamboo Bar, a bar that offers unique local touches. Likewise, Mag Cafe provides an excellent alternative for a fun evening.

Raise a toast to the start of your 6-day road trip in Italy!

Embark on another extraordinary experience on day 2 of your road trip in Italy. Today, you will make 1 stop and experience some of the highlights of Milan. At the end of the day, you will enjoy the comforts of a top-rated hotel in Genoa, which will be your home away from home for 1 night.

Make Duomo Di Milano Museum your first stop of the day. Previous visitors have rated this art museum an average of 4.8 out of 5 stars in 138,554 reviews. More than 341,609 people visit this place of interest every year.

Next up, make a stop at Galleria Vittorio Emanuele Ii. With an average rating of 4.7 out of 5 stars by 91,394 visitors, it's easy to understand why so many people visit this commercial gallery every year.

La Scala is another attraction you can visit on this day of your vacation. This opera house has an average rating of 4.7 out of 5 stars by 26,219 visitors.

When you’re finished at La Scala, the perfect next stop is Sforzesco Castle Art Library. This library is rated an average of 4.6 out of 5 stars in 68,714 reviews.

If you’re keen to explore even more, then consider a visit to Parco Sempione. This park is a top place to visit, with a rating of 4.6 out of 5 stars from 72,914 reviews.

After soaking up all the sights of today's itinerary, you'll be ready to hit the road in the direction of your accommodation in Genoa. Genoa offers plenty of top-rated hotels and other places to stay on any travel budget. Take some time to relax before you head out to explore.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Genoa. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Experience a taste of local culinary excellence while in Genoa by securing a table at San Giorgio. An esteemed 1-star Michelin restaurant, it features an exceptional modern, and ligurian menu. For an alternative taste experience, visit The Cook, famous for its scrumptious modern dishes. This 1-star Michelin venue consistently impresses guests, making it a standout addition to your holiday plans. Looking for another choice? Discover Il Marin, a local favorite celebrated for its exquisite seafood, and contemporary cuisine in Genoa. Located in the heart of the city, this 1-star Michelin restaurant is an ideal pick for seafood, and contemporary cuisine lovers seeking top-notch culinary experiences.

After your delicious meal, get a taste of the vibrant nightlife with a visit to Scurreria Beer & Bagel, known for its inviting atmosphere. La Lepre is another great option if you’re looking for a place to get the night started.

Raise your glass and celebrate another amazing day of your road trip in Italy!

On day 3 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 2 destinations, Genoa, and Pisa. When you’re not sightseeing, take time to relax at your selected hotel in Florence, where you’ll be staying for 2 nights.

Kick off the day at Piazza De Ferrari, a top pick for today’s sightseeing. This square is rated an average of 4.6 out of 5 stars in 34,312 reviews.

Today is also your chance to visit Aquarium Of Genoa. Aquarium Of Genoa is a public aquarium with an average rating of 4.5 out of 5 stars from 62,259 reviews. Attracting more than 1,200,000 yearly visitors, this place of interest is an attraction you don’t want to miss out on.

After soaking in Genoa’s unique atmosphere, jump into the car with a full heart and drive in the direction of your next destination: Pisa. Expect your car journey to take a minimum of 2 hours 5 min. When you arrive in Pisa, it's time to take a break from the road.

Your sightseeing of the day begins at Leaning Tower Of Pisa, a remarkable bell tower where it’s easy to get lost in exploration. This top attraction is rated an average of 4.7 out of 5 stars in 116,882 reviews. Each year, this popular place of interest welcomes approximately 3,200,000 visitors.

Next, satisfy your wanderlust at Piazza Del Duomo, Pisa. This square has an average rating of 4.7 out of 5 stars from 104,550 travelers.

When you’re done exploring for the day, you’ll drive to Florence, where you'll have a hotel waiting for you. Check in and spend some time relaxing before you head out to explore the city.

As dinnertime approaches, it's time to head out for a bite to eat in Florence. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Begin your culinary exploration in Florence by securing a reservation at Enoteca Pinchiorri. This renowned restaurant holds 3 Michelin star and offers an exceptional menu of italian contemporary cuisine. For another dining delight, visit Santa Elisabetta, celebrated for its delectable creative, and mediterranean menu. This acclaimed 2-star Michelin-recipient consistently leaves guests satisfied, making it a must-visit during your holiday. Looking for a different experience? Discover Gucci Osteria da Massimo Bottura, a top local spot known for its tantalizing italian contemporary, and international menu. With a 1-star Michelin recognition, it guarantees an exceptional dining adventure.

Round off your dining experience by visiting Manifattura, a prime location for a drink. Alternatively, explore the distinctive characteristics of Se·sto On Arno Rooftop Bar, a bar catering to every mood and preference. Archea Brewery likewise offers a unique atmosphere, perfect for a memorable night out.

Raise your glass to another unforgettable day in Italy!

Day 4 offers a multitude of experiences. You will stay in Florence for 1 night more, offering you enough time to explore at a relaxed pace.

Make Piazzale Michelangelo your first stop of the day. Previous visitors have rated this square an average of 4.8 out of 5 stars in 77,744 reviews.

Next up, make a stop at Uffizi Gallery. With an average rating of 4.7 out of 5 stars by 61,794 visitors, it's easy to understand why so many people visit this national museum every year. In fact, this attraction welcomes 2,011,219 annual visitors.

Ponte Vecchio is another attraction you can visit on this day of your vacation. This deck arch bridge has an average rating of 4.7 out of 5 stars by 118,099 visitors.

When you’re finished at Ponte Vecchio, the perfect next stop is Piazza Della Signoria. This square is rated an average of 4.8 out of 5 stars in 66,956 reviews.

If you’re keen to explore even more, then consider a visit to Galleria Dell'accademia. This national museum is a top place to visit, with a rating of 4.6 out of 5 stars from 34,429 reviews. Galleria Dell'accademia hosts around 1,719,645 visitors every year.

If you have an appetite for more adventure, check out the fantastic selection of tours and tickets offered in Florence on this day of your trip. You'll find the most recommended ones below.

After a day of adventure, treat yourself to an exquisite dinner at one of Florence's best restaurants.

Treat yourself to a wonderful meal at Trattoria Da Burde, a top-rated dining spot in Florence. If you're in the mood for something new, try Ristorante Buca Mario, another premier location with a delectable menu. You might also want to book a table at Eataly Firenze. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Florence.

As the sun sets on another day of adventure, rest up and recharge for the next leg of your road trip in Italy.

On day 5 of your road trip in Italy, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Florence, and Bologna. In the evening, you’ll end up in Milan, where you will stay for 1 night.

Journey into the unknown at Cathedral Of Santa Maria Del Fiore, a unique attraction awaiting your visit. This remarkable church has an average rating of 4.8 out of 5 stars from 76,359 reviews.

When you’re ready to continue your sightseeing, Central Market is a recommended place to visit. This sightseeing destination is rated an average of 4.4 out of 5 stars in 43,100 reviews.

As you’ve unraveled the marvels of Florence, it’s time to gear up for the next part of your road trip adventure. Under favorable conditions, your drive to Bologna may take around 1 hour 29 min. Upon your arrival in Bologna, you’ll be greeted with the opportunity to do some sightseeing and exploring.

Start your sightseeing with a visit to Piazza Maggiore. This square is a popular stop on travelers’ itineraries in Bologna, with an average rating of 4.7 out of 5 stars by 64,523 visitors.

At the end of the day, you will drive to Milan, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As you explore more of Milan, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Prepare for an extraordinary culinary adventure in Milan by booking a table at Enrico Bartolini al Mudec, a 3-star Michelin restaurant that boasts an exceptional creative menu. For a different flavor experience, head to Seta by Antonio Guida, renowned for its delectable international, and contemporary dishes. This 2-star Michelin restaurant consistently wows guests, making it a memorable stop during your holiday. Looking for another option? Visit Il Luogo Aimo e Nadia, a local gem known for its delightful italian contemporary, and modern cuisine in Milan. Nestled in the city's heart, this 1-star Michelin restaurant is a perfect choice for discerning restaurant-goers seeking a new experience.

Extend your evening after a delightful meal by visiting Kilburn Cocktail Bar Milano, which offers the perfect atmosphere for a night out. Moreover, Bar Frida is another popular option for a drink or two. Likewise, The Friends Pub Milano also provides a great ambiance for reminiscing about the day and raising a toast to your vacation.

Say good night to Milan and look forward to another great day of your road trip in Italy!

Day 6 of your road trip in Italy is your departure day. This is your chance to catch a last glimpse of Milan before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

On your last day in Italy, take time to indulge in shopping at Milan’s popular marketplace. Look for keepsakes or souvenirs to remind you of your trip.

Make Piazza Gae Aulenti your first stop of the day. Previous visitors have rated this square an average of 4.6 out of 5 stars in 30,398 reviews.

Before you conclude your road trip in Italy, drop by another restaurant for a last chance at a memorable dining experience in Milan.

Dine in style at Vento di Sardegna, a top recommendation for dinner tonight. Or, for a change of pace, Palazzo Parigi Hotel & Grand Spa Milano boasts a menu that's sure to impress.

You’ll then say farewell to Milan. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Italy!