6-Day Sicily Self-Drive Road Trip With Itinerary from Palermo to Agrigento and surrounding area

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Explore the best of Sicily on a 6-day road trip! Uncover hidden gems and experience the rich culture firsthand as you journey through Palermo, Nubia, Xitta, Erice, Agrigento, and Castellammare del Golfo. This road trip itinerary in Sicily seamlessly combines exploration with relaxation.

This perfectly planned road trip itinerary in Sicily takes you through some of the best places to see in the country. You will spend 4 nights in Palermo and 1 night in Agrigento. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Sicily. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have got you covered.

Upon arriving in Palermo, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Sicily on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Sicily. Palermo Cathedral and Quattro Canti are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Norman Palace, learn more about the unique Catacombe Dei Cappuccini, and immerse yourself in the vibrant atmosphere of Foro Italico.

As you hit the open road and drive through Palermo, Nubia, Xitta, Erice, Agrigento, and Castellammare del Golfo, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Sicily. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Sicily.

Throughout your road trip in Sicily, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Sicily.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodation, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Sicily fill up quickly, so book your spot early. Select a date and start planning your road trip in Sicily today!

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Itinerary summary

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Days
Destination
Attractions
Overnight
Day
City & Overnight
Attractions
Foro Italico
Catacombe dei CappucciniNorman PalacePalermo CathedralSantuario di Santa Rosalia, Palermo
Orto botanico di PalermoChurch of St. Mary of the AdmiralFontana PretoriaQuattro CantiRiserva Naturale di Capo Gallo
Salt MuseumSaline di Trapani e PacecoCastello di Venere
Riserva Naturale Orientata dello ZingaroCala Mazzo di SciaccaBelvedere Castellammare del GolfoMarina di Castellammare del Golfo
Garden Zisa

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Day 1

Day 1

  • Palermo - Arrival day
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  • Foro Italico
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Say hello to Palermo! Your exciting road trip through Italy is just about to start. Navigating the top places to see in the region is a breeze with a car. The rental vehicle of your choice will be ready for pickup upon your arrival in the city. You will stay in Palermo for 3 nights before you continue your adventure!

Palermo is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Foro Italico, or just taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

As afternoon approaches, head to your chosen hotel in Palermo. Check-in typically starts around 2 to 4 PM at hotels in Italy. We recommend staying at a hotel in a central location for easy access to the best attractions, restaurants, and bars in the city.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Palermo, it's often a good idea to reserve a table in advance.

Treat yourself to a wonderful meal at Cotto e Bollito, a top-rated dining spot in Palermo. If you're in the mood for something new, try Bebop, another premier location with a delectable menu. You might also want to book a table at Eremiti Restaurant. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Palermo.

After savoring a delicious meal, step into the vibrant nightlife at Malox Cult, where the evening is just getting started. In the same way, Ai Giudici offers a unique charm perfect for experiencing the local bar scene in Palermo. Bar Italico is another top-recommended bar that is sure to get you into the mood for some dancing and celebrating.

Raise a toast to the start of your 6-day road trip in Sicily!

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Day 2

Day 2

  • Palermo
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Drive 33 km, 1 hour 22 min

  • Catacombe dei Cappuccini
  • Norman Palace
  • Palermo Cathedral
  • Santuario di Santa Rosalia, Palermo
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On day 2 of your road trip, you will have an entire day to explore Palermo. You’ll stay in Palermo for 2 nights and discover all the best things to see and do in the area.

Today’s well-planned self-sightseeing route offers several picturesque spots, historic treasures, and sacred landmarks. Whether you decide to explore Palermo on foot, use public transport, or join a guided tour, there are a few attractions you don’t want to miss. Catacombe Dei Cappuccini is the first of them. Spend some time admiring this heritage-rich cemetery before continuing your journey. Norman Palace is your next stop. This well-known palace is one of the best-rated sights in Palermo.

Consider grabbing some lunch or a light snack to keep your energy going. Beyond the above-mentioned attractions, today is also the perfect time to visit Palermo Cathedral. This picture-perfect church is a sight to behold. To round off your sightseeing experience, visit Santuario Di Santa Rosalia, Palermo.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Sicily is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Palermo. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Have a memorable dining experience in Palermo by booking a table at Buatta Cucina Popolana, renowned as a Bib Gourmand restaurant presenting an exceptional sicilian menu. For a different culinary experience in Palermo, Mec Restaurant shines as one of the top destinations, known for its delicious sicilian and contemporary cuisine. This 1-star Michelin-awardee earns consistently high praises from previous guests, making it a must-visit addition to your holiday experience. If you're looking for an alternative, Gagini Restaurant is known as a top local spot for its delicious creative and contemporary cuisine in Palermo. This 1-star Michelin awardee is a highly recommended choice for an unforgettable meal.

Let the evening flow smoothly from dinner to drinks at Spina Bar Palermo, a top-rated bar in the area. For other recommendations, Torrefazione Castagnetta Massimiliano (gelateria) provides a perfect setting for rounding out your night with style and great drinks. Likewise, Monkey Pub offers a memorable night with diverse drink options and excellent service.

Celebrate another amazing day of your road trip adventure in Sicily!

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Day 3

Day 3

  • Palermo
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Drive 41 km, 1 hour 42 min

  • Orto botanico di Palermo
  • Church of St. Mary of the Admiral
  • Fontana Pretoria
  • Quattro Canti
  • Riserva Naturale di Capo Gallo
  • More

Day 3 of your road trip will take you to the best attractions Palermo has to offer. Cherish the 1 night you have left in Palermo by discovering the best things there are to see and do in the city.

Get ready for an exciting day in Palermo. Today’s sightseeing agenda includes a botanical garden, a church, a monument, a public square, a nature reserve and much more! Begin your adventure at Orto Botanico Di Palermo. This is an often recommended botanical garden you should not miss. Another must-see is Martorana, a curiosity-inducing church in Palermo.

When you’re ready for the next sight, head to Fontana Pretoria. From there, take a leisurely stroll to Quattro Canti, another of the city’s well-known attractions. We recommend continuing your self-guided tour at Riserva Naturale Di Capo Gallo, a romantic place of interest in the city.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Sicily is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

As you explore more of Palermo, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Dine in style at Splendid Hotel la Torre, a top recommendation for dinner tonight. Or, for a change of pace, Ristorantino Sobremesa boasts a menu that's sure to impress. Also, be sure to check out Ristorante Quattro mani. Known as a local hotspot, it’s a great choice for tonight in Palermo.

Keep the evening going at Bar Touring, a great choice for enjoying the after-dinner hours with a drink. You could also go to Palermo Football Store, which offers a similarly pleasant setting and great drinks. Another option is Goccio - L’arte Del Miscelare, which provides an inviting environment for unwinding after a busy day out.

Relax and recharge in preparation for another adventurous day in Sicily!

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Day 4

Day 4

  • Palermo
  • Agrigento
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Drive 316 km, 4 hours 31 min

  • Salt Museum
  • Saline di Trapani e Paceco
  • Castello di Venere
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On day 4 of your road trip in Sicily, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Nubia, Xitta, and Erice. In the evening, you’ll end up in Agrigento, where you will stay for 1 night.

Today’s route brings family-friendly attractions, breathtaking views, and picturesque spots. The first attraction of today is Salt Museum. This intriguing museum is a breathtaking place to see in Palermo. Continue your discovery at Saline Di Trapani E Paceco, an eye-catching nature reserve with stories to tell.

As you stroll around Palermo, take in the distinct atmosphere and learn what makes this village so unique. Maximize your sightseeing with a visit to Castello Di Venere. This beloved castle offers a visually striking encounter with Palermo. Whether you decide to get entrance tickets for all attractions or you prefer admiring from a distance, amazing experiences await on this day in Palermo.

When you’re done exploring for the day, you’ll drive to your hotel in Agrigento. Check in and spend some time relaxing before you head out to tour the city.

As you explore more of Agrigento, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Don’t miss out on dining at Ambasciata di Sicilia, a top-rated dining destination in Agrigento. If you're in the mood to try something new, consider Le Cuspidi, another top spot with a mouthwatering menu. You might also want to secure a reservation at Yellove RistoVintage. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Agrigento this evening.

Take some time to reflect on your day and savor another beautiful night in Sicily.

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Day 5

Day 5

  • Agrigento
  • Palermo
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Drive 252 km, 4 hours 17 min

  • Riserva Naturale Orientata dello Zingaro
  • Cala Mazzo di Sciacca
  • Belvedere Castellammare del Golfo
  • Marina di Castellammare del Golfo
  • More

On day 5 of your exciting self-drive vacation in Sicily, you’ll soak in the magnificence of 2 destinations, San Vito Lo Capo and Castellammare del Golfo. When you’re not sightseeing, take time to relax at your selected hotel in Palermo, where you’ll be staying for 1 night.

Immerse yourself in Agrigento’s rich culture with today's sightseeing itinerary. Start your journey at Riserva Naturale Orientata Dello Zingaro, Ingresso Sud. This mesmerizing nature reserve is sure to ignite your curiosity. Next, dive into the mesmerizing features of Cala Mazzo Di Sciacca, a must-visit beach in the region.

In between sights, stop by local stores, picturesque photo spots, and small eateries. When you’re ready for your next attraction, proceed to Belvedere Castellammare Del Golfo, a curiosity-inducing observation deck. For a change of scene, check out Marina Di Castellammare Del Golfo, known for its romantic features.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Palermo. Palermo offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Palermo. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Treat yourself to a delightful dinner at Trattoria Ai Cascinari, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Villa Boscogrande - Chef Natale Di Maria? It's another excellent option with a diverse menu. Consider reserving a table at MadoniEAT as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Palermo.

Unwind after your meal by stepping into Pasticceria Massaro. This venue is celebrated for its extensive drink selections and cozy vibes. Alternatively, Bar Sanremo - Palermo offers a dynamic and energetic atmosphere for a glass or two. Don’t overlook Bar Touring, another top-rated bar in the area.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in in Sicily.

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Day 6

Day 6

  • Palermo - Departure day
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  • Garden Zisa
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Day 6 of your road trip in Sicily is your departure day. This is your chance to catch a last glimpse of Palermo before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, we recommend visiting Giardino Della Zisa, a visually striking park before you head out.

As your final day in Sicily unfolds, enjoy a last-minute shopping spree in Palermo's best shopping area. Enjoy finding the perfect gift or keepsake to remind you of your wonderful trip to Sicily.

Before you conclude your road trip in Sicily, drop by another restaurant for a last chance at a memorable dining experience in Palermo.

Savor the flavors at Ristorante Ferro, a top pick for dinner tonight. Alternatively, RISTORANTE PRIMI PIATTI beckons with its unique menu offerings.

You’ll then say farewell to Palermo. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Sicily!

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