6-Day Italy Self-Drive Road Trip With Itinerary from Pescara traveling west to Rome

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Experience the freedom of the open road in Italy as you embark on an unforgettable 6-day road trip! This experience caters to every traveler, featuring destinations like Pescara, Rome, Tivoli, Orvieto, and L'aquila.

This perfectly planned road trip itinerary in Italy takes you through some of the best places to see in the country. You will spend 2 nights in Pescara and 3 nights in Rome. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Italy. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have got you covered.

Upon arriving in Pescara, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Italy on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Italy. Trevi Fountain and Colosseum are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Pantheon, learn more about the unique Piazza Navona, and immerse yourself in the vibrant atmosphere of St. Peter's Basilica.

As you hit the open road and drive through Pescara, Rome, Tivoli, Orvieto, and L'aquila, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Italy. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Italy.

Throughout your road trip in Italy, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Italy.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodation, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Italy fill up quickly, so book your spot early. Select a date and start planning your road trip in Italy today!

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Itinerary summary

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Days
Destination
Attractions
Overnight
Day
City & Overnight
Attractions
Locomotiva FS 740351
ColosseumRoman ForumPantheonSpanish StepsPiazza di SpagnaTrevi Fountain
St Peter's BasilicaSistine ChapelVatican MuseumsPiazza NavonaTrastevereVia del Corso
Villa d'EsteFontana dell'OrganoHadrian's VillaOrvieto Cathedral
Forte SpagnoloPorta CastelloBasilica of San Bernardino
Parrocchia Spirito Santo

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Day 1

Day 1

  • Pescara - Arrival day
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  • Locomotiva FS 740351
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Welcome to Pescara, the perfect starting point for your road trip in Italy! Pick up your rental car and let the adventure begin. You will spend 1 night immersing yourself in Pescara's charm before embarking on the next leg of your journey.

Pescara is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Locomotiva Fs 740.351, or just taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

Find your way to your hotel in Pescara. We recommend choosing a hotel in a central location for easy exploring. Check-in typically starts between 2 and 4 PM at hotels in Italy. Settle in and make plans for the evening.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Pescara, it's often a good idea to reserve a table in advance.

Treat yourself to a delightful dinner at Taverna 58, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Ristorante Carlo Ferraioli? It's another excellent option with a diverse menu. Consider reserving a table at Sesamo Nero as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Pescara.

Cap off your culinary experience with a visit to some of the most celebrated bars in the area. For instance, Posa Caffè Pescara stands out as an excellent choice for a post-dinner cocktail. Alternatively, Bar Mixer offers an ideal atmosphere to enjoy the pleasures of the night. Temple Bar Irish Pub is also a great option that provides a perfect setting for a relaxing evening.

Raise a toast to the start of your 6-day road trip in Italy!

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Day 2

Day 2

  • Pescara
  • Rome
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Drive 214 km, 3 hours 27 min

  • Colosseum
  • Roman Forum
  • Pantheon
  • Spanish Steps
  • Piazza di Spagna
  • Trevi Fountain
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On day 2 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 1 destination, Rome. When you’re not sightseeing, take time to relax at your selected hotel in Rome, where you’ll be staying for 3 nights.

Prepare for a day full of fun adventures, breathtaking views, and picturesque spots. When you’re ready, kick off your sightseeing adventure at Colosseum. This world-famous archeological site is a must-visit for anyone seeking a unique vacation experience. Another sight you shouldn’t miss is Roman Forum, one of the city’s best highlights.

Next, check out Pantheon, one of the most timeless places to see in Pescara. This monument is a favorite among locals and travelers alike. Enjoy some downtime and refreshments before continuing to your next stop, Spanish Steps. Wander around and soak in the romantic atmosphere this public square offers. Then, head to Piazza Di Spagna, a top-rated public square that adds another dimension to your day. Finally, visit the iconic Trevi Fountain, the last of our attraction recommendations for today.

At the end of the day, you will drive to Rome, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As you explore more of Rome, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Make sure to reserve a table at La Bottega Roma, an iconic dining spot in Rome. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Pasta In Corso, a popular restaurant in Rome. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Trattoria Vecchia Roma, a hidden gem nestled in Rome. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Cap off your dinner by heading to La Botticella Of Poggi Giovanni, ideal for a leisurely evening with a drink in hand. Almalu Trastevere is another bar that offers an enjoyable setting. Similarly, Bar Viminale Di Pepi Maurilio is also a popular place to go on a night out, perfect for relaxing and socializing.

Raise your glass and celebrate another amazing day of your road trip in Italy!

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Day 3

Day 3

  • Rome
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Drive 9 km, 59 min

  • St Peter's Basilica
  • Sistine Chapel
  • Vatican Museums
  • Piazza Navona
  • Trastevere
  • Via del Corso
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On day 3 of your road trip in Italy, you’ll start and end your day in Rome, but spend the day exploring what’s beyond the city. Since you will return to Rome for 2 nights more, there’s no need to rush. Experience Vatican City and Rome to the fullest today with this curated day itinerary!

A visit to Trastevere in Vatican City is a must on the agenda today. This neighborhood is full of hidden gems and character, perfect for a leisurely stroll. Plus, you’ll be close to some of the city’s most famous sights. Don’t forget to check out Via del Corso as well, a street that adds another layer to your exploration.

Immerse yourself in Rome’s rich culture with today's sightseeing itinerary. Start your journey at St. Peter's Basilica.

In between sights, stop by local stores, picturesque photo spots, and small eateries. When you’re ready for your next attraction, proceed to Vatican Museums, a timeless art museum. For a change of scene, check out Piazza Navona, known for its romantic features.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Rome.

As you explore more of Rome, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Don’t miss out on dining at RomAntica, a top-rated dining destination in Rome. If you're in the mood to try something new, consider Coso Ristorante, another top spot with a mouthwatering menu. You might also want to secure a reservation at DEROMA - Farine Romane. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Rome this evening.

Extend your evening after a delightful meal by visiting Sant' Eustachio Caffè, which offers the perfect atmosphere for a night out. Moreover, Yellowsquare Rome is another popular option for a drink or two. Likewise, Caffè Portofino also provides a great ambiance for reminiscing about the day and raising a toast to your vacation.

Relax and reminisce about your day in Italy and look forward to more memorable moments to come!

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Day 4

Day 4

  • Rome
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Drive 299 km, 4 hours 17 min

  • Villa d'Este
  • Fontana dell'Organo
  • Hadrian's Villa
  • Orvieto Cathedral
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Greet day 4 of your road trip in Italy with a smile and start your day with a hearty breakfast. You will return to Rome for your remaining 1 night in the city later today, but first, it’s time for some exploring! On the agenda for this day, you’ll find only the best things to see and do in Tivoli and Orvieto.

Brace yourself for today’s incredible lineup of attractions in Rome, featuring fun adventures, romantic experiences, and breathtaking views. Start at Villa D'este, a notable palace in the town. Then, head to Fontana Dell'organo and soak in the ambiance of this remarkable monument.

There are many interesting places to see in Rome, and when you are ready for more, go to Hadrian's Villa. This is one of the town’s most frequently visited picture-perfect spots of interest. After exploring the archeological site, visit the popular Orvieto Cathedral.

When you’re done exploring for the day, you’ll return to Rome and your accommodation.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Rome. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Treat yourself to a delightful dinner at Hotel de Russie, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try La Taverna Italiana? It's another excellent option with a diverse menu. Consider reserving a table at The Parrot Bar as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Rome.

After your delicious meal, get a taste of the vibrant nightlife with a visit to The Apartment Bar Roma, known for its inviting atmosphere. Hotel Hassler Roma is another great option if you’re looking for a place to get the night started.

Savor another day of unforgettable experiences in Italy!

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Day 5

Day 5

  • Rome
  • Pescara
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Drive 219 km, 3 hours 4 min

  • Forte Spagnolo
  • Porta Castello
  • Basilica of San Bernardino
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Embark on another extraordinary experience on day 5 of your road trip in Italy. Today, you will make 1 stop and experience some of the highlights of L'aquila. At the end of the day, you will enjoy the comforts of a top-rated hotel in Pescara, which will be your home away from home for 1 night.

Get ready for an exciting day in Rome. Today’s sightseeing agenda includes a castle, a monument, and a church. Begin your adventure at Forte Spagnolo. This is an intriguing castle you should not miss. Another must-see is Porta Castello, an intriguing monument in Rome.

When you’re ready for the next sight, head to Basilica Of San Bernardino.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Pescara. Pescara offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

After a day of adventure, treat yourself to an exquisite dinner at one of Pescara's best restaurants.

Enjoy a delicious meal at Ciacco, a top-rated dining destination in Pescara. If you're in the mood to try something new, consider Bar Sara, another top spot with a mouthwatering menu. You might also want to secure a reservation at Ristorante Franco. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Pescara this evening.

After savoring a delicious meal, step into the vibrant nightlife at Bar Napoli, where the evening is just getting started. In the same way, Bar Supermarket offers a unique charm perfect for experiencing the local bar scene in Pescara. Post Bar is another top-recommended bar that is sure to get you into the mood for some dancing and celebrating.

Celebrate another amazing day of your road trip adventure in Italy!

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Day 6

Day 6

  • Pescara - Departure day
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  • Parrocchia Spirito Santo
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Day 6 of your road trip in Italy is your departure day. This is your chance to catch a last glimpse of Pescara before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, begin at Parrocchia Spirito Santo. This locally appreciated church is a popular place to see in the city.

On your last day in Italy, take time to indulge in shopping at Pescara’s popular marketplace, Centro Commerciale Pescara Porta Nuova. Look for keepsakes or souvenirs to remind you of your trip.

Before you conclude your road trip in Italy, drop by another restaurant for a last chance at a memorable dining experience in Pescara.

You’ll then say farewell to Pescara. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Italy!

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