6-Day Italy Road Trip from Rome to Florence, L'aquila, and Naples and surrounding area

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Experience the freedom of the open road in Italy as you embark on an unforgettable 6-day road trip! This experience caters to every traveler, featuring destinations like Rome, Florence, L'aquila, and Naples.

This perfectly planned road trip itinerary in Italy takes you through some of the best places to see in the country. You will spend 2 nights in Rome, 1 night in Florence, 1 night in L'aquila, and 1 night in Naples. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Italy. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have got you covered.

Upon arriving in Rome, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Italy on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Italy. Trevi Fountain and Colosseum are just a couple of the bucket-list attractions that await your discovery.

As you hit the open road and drive through Rome, Florence, L'aquila, and Naples, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Italy. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Italy.

Throughout your road trip in Italy, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Italy.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodation, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Italy fill up quickly, so book your spot early. Select a date and start planning your road trip in Italy today!

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Day 1

Day 1 – Rome - arrival day

  • Rome - Arrival day
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  • Trevi Fountain
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Say hello to Rome! Your exciting road trip through Italy is just about to start. Navigating the top places to see in the region is a breeze with a car. The rental vehicle of your choice will be ready for pickup upon your arrival in the city. You will stay in Rome for 1 night before you continue your adventure!

Rome is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Trevi Fountain or taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

Make your way to your chosen hotel. Check-in typically starts between 2 and 4 PM in Rome. Make yourself at home and enjoy some downtime before heading out again.

As dinnertime approaches, it's time to head out for a bite to eat in Rome. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Make sure to book a table at La Bottega Roma, a popular restaurant in Rome. This acclaimed restaurant and its mouthwatering dishes have earned the admiration of countless food lovers. Alternatively, experience a taste of Rome at RomAntica, a popular local restaurant. With a menu designed to impress, it promises a journey of flavors that will leave you captivated. Another top-rated restaurant to try is Coso Ristorante. As a dining spot that gains high praise from guests, it’s an ideal choice to enhance your time to Rome tonight.

Round off your dining experience by visiting La Botticella Of Poggi Giovanni, a prime location for a drink. Alternatively, explore the distinctive characteristics of Sant' Eustachio Caffè, a bar catering to every mood and preference. Caffè Portofino likewise offers a unique atmosphere, perfect for a memorable night out.

Raise a toast to the start of your 6-day road trip in Italy!

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Day 2

Day 2 – Rome, and Florence

  • Florence
  • Rome
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Drive 290 km, 4 hours 6 min

  • Roman Forum
  • Piazza di Spagna
  • Colosseum
  • Pantheon
  • Piazza Navona
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On day 2 of your road trip in Italy, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Rome. In the evening, you’ll end up in Florence, where you will stay for 1 night.

When you’re ready for some sightseeing, make your way to Roman Forum. This much-appreciated square is rated 4.7 out of 5 stars in 114,450 reviews.

Next up is Piazza Di Spagna. This square has an average rating of 4.7 out of 5 stars from 113,658 visitors.

Another top sightseeing recommendation is Colosseum. This roman amphitheatre has been rated 4.7 out of 5 stars in 328,821 reviews. Every year, 7,400,000 travelers include this attraction on their travel itinerary.

Pantheon is another attraction you have the opportunity to visit today. This roman temple has an average rating of 4.8 out of 5 stars from 189,682 reviews. This popular attraction gets 30,000,000 visits every year.

To continue your sightseeing, head over to Piazza Navona. This square is rated an average of 4.7 out of 5 stars in 158,771 reviews.

At the end of the day, you will drive to Florence, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

After a day of adventure, treat yourself to an exquisite dinner at one of Florence's best restaurants.

Experience a symphony of flavors at Enoteca Pinchiorri in Florence by securing a reservation in advance. Renowned for its 3-star Michelin distinction, Enoteca Pinchiorri delights its guests with its exceptional variety of meals showcasing delicious italian contemporary cuisine. For a palate-pleasing alternative, make sure to dine at Santa Elisabetta, acclaimed for its delectable creative, and mediterranean specialties. This local 2-star Michelin establishment consistently satisfies guests, ensuring an unforgettable holiday experience. Want to go on another culinary journey? Delight your senses at Gucci Osteria da Massimo Bottura, a top-rated restaurant known for its outstanding menu. Known as a top-rated 1-star Michelin establishment, it's a top choice for italian contemporary, and international cuisine in the city.

After savoring a delicious meal, step into the vibrant nightlife at Manifattura, where the evening is just getting started. In the same way, Se·sto On Arno Rooftop Bar offers a unique charm perfect for experiencing the local bar scene in Florence. Archea Brewery is another top-recommended bar that is sure to get you into the mood for some dancing and celebrating.

Savor another day of unforgettable experiences in Italy!

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Day 3

Day 3 – Florence, and L'aquila

  • L'Aquila
  • Florence
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Drive 365 km, 4 hours 29 min

  • Piazza della Signoria
  • Cathedral of Santa Maria del Fiore
  • Ponte Vecchio
  • Piazzale Michelangelo
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Experience an unparalleled adventure on day 3 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 1 vibrant destinations - Florence. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in L'aquila. You will spend 1 night here for some well-deserved relaxation.

Begin your sightseeing with a visit to Piazza Della Signoria. This extraordinary square is rated an average of 4.8 out of 5 stars by 66,956 visitors.

Next, make your way to Cathedral Of Santa Maria Del Fiore. This top attraction is a church with an average rating of 4.8 out of 5 stars by 76,359 visitors.

We also recommend a visit to Ponte Vecchio. This deck arch bridge is rated 4.7 out of 5 stars by 118,099 travelers.

If you’re keen to keep exploring, visit Piazzale Michelangelo. This highly recommended sightseeing destination has received an average rating of 4.8 out of 5 stars from 77,744 travelers.

After soaking up all the sights of today's itinerary, you'll be ready to hit the road in the direction of your accommodation in L'aquila. L'aquila offers plenty of top-rated hotels and other places to stay on any travel budget. Take some time to relax before you head out to explore.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in L'aquila. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Dive into a culinary adventure like no other in L'aquila by booking a table at FØRMA contemporary restaurant. This popular restaurant holds a Bib Gourmand award and offers an exceptional menu of contemporary, and creative cuisine. If you're in the mood to try something new, consider DECA, another top spot with a mouthwatering menu.

Cap off your dinner by heading to Art Cafè L'aquila, ideal for a leisurely evening with a drink in hand.

Raise your glass to another unforgettable day in Italy!

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Day 4

Day 4 – L'aquila, Vatican City, and Naples

  • Naples
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Drive 355 km, 4 hours 38 min

  • St Peter's Basilica
  • Sistine Chapel
  • Vatican Museums
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Embark on another extraordinary experience on day 4 of your road trip in Italy. Today, you will make 1 stop and experience some of the highlights of Vatican City. At the end of the day, you will enjoy the comforts of a top-rated hotel in Naples, which will be your home away from home for 1 night.

As you’ve unraveled the marvels of L'aquila, it’s time to gear up for the next part of your road trip adventure. Set course for Vatican City! Under favorable conditions, your drive to Vatican City may take around 1 hour 39 min. Upon your arrival in Vatican City, you’ll be greeted with the opportunity to do some sightseeing and exploring.

Begin your sightseeing with a visit to St. Peter's Basilica. This extraordinary major basilica is rated an average of 4.8 out of 5 stars by 131,043 visitors. Each year, around 11,000,000 people visit this site to learn more about it.

Next, make your way to Sistine Chapel. This top attraction is a chapel with an average rating of 4.7 out of 5 stars by 52,083 visitors.

We also recommend a visit to Vatican Museums. Hosting 1,612,530 visitors every year, Vatican Museums is one of the most popular places to visit in Vatican City. This art museum is rated 4.6 out of 5 stars by 133,310 travelers.

When you’re done exploring for the day, you’ll drive to Naples, where you'll have a hotel waiting for you. Check in and spend some time relaxing before you head out to explore the city.

As dinnertime approaches, it's time to head out for a bite to eat in Naples. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Experience a taste of local culinary excellence while in Naples by securing a table at Veritas. An esteemed 1-star Michelin restaurant, it features an exceptional campanian, and contemporary menu. For an alternative taste experience, visit Il Comandante, famous for its scrumptious creative, and mediterranean dishes. This 1-star Michelin venue consistently impresses guests, making it a standout addition to your holiday plans. Looking for another choice? Discover ARIA, a local favorite celebrated for its exquisite contemporary, and modern cuisine in Naples. Located in the heart of the city, this 1-star Michelin restaurant is an ideal pick for contemporary, and modern cuisine lovers seeking top-notch culinary experiences.

Explore the vibrant nightlife at Happening Cocktail Bar after your meal, a hub for lively evenings and memorable moments. Or, head to Shanti Art Musik Bar for a great selection of flavorful drinks and a charming setting. Furthermore, Gran Caffè Gambrinus is perfect for those looking to extend their night with a touch of local flavor.

Celebrate another amazing day of your road trip adventure in Italy!

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Day 5

Day 5 – Naples, and Rome

  • Rome
  • Naples
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Drive 237 km, 3 hours 26 min

  • Piazza del Plebiscito
  • Ovo Castle
  • Naples National Archaeological Museum
  • Museo Cappella Sansevero
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On day 5 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 1 destination, Naples. When you’re not sightseeing, take time to relax at your selected hotel in Rome, where you’ll be staying for 1 night.

Take the opportunity to see Piazza Del Plebiscito. This attraction has an average rating of 4.7 out of 5 stars from 58,141 visitors.

Ovo Castle is another sightseeing hotspot in the area. This sightseeing destination has been rated an average of 4.6 out of 5 stars by 33,595 travelers.

Naples is also the home of Naples National Archaeological Museum. This archaeological museum gets more than 616,878 visitors on an annual basis. Around 27,352 people have rated this archaeological museum an average of 4.6 out of 5 stars.

Another place you’ll want to visit is Cappella Sansevero, which hosts up to 175,138 visitors every year. With an average rating of 4.7 out of 5 stars from a total of 25,405 reviews, a visit to this former church is a great idea.

At the end of the day, you will drive to Rome, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As you explore more of Rome, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Get ready for an unforgettable culinary journey in Rome by reserving a table at La Pergola. Renowned as a 3-star Michelin restaurant, it offers an exceptional mediterranean, and contemporary menu. For a different taste experience, head to Il Pagliaccio, recognized for its delicious creative, and innovative dishes. This 2-star Michelin restaurant consistently impresses guests, ensuring a memorable addition to your holiday. Looking for another option? Make sure to visit Enoteca La Torre, a local favorite known for its delightful mediterranean, and creative cuisine in Rome. Nestled in the heart of the city, this restaurant with 2 Michelin star is an ideal choice for discerning mediterranean, and creative foodies seeking culinary excellence.

After enjoying a fulfilling meal, continue your evening at The Apartment Bar Roma, ideal for those looking to unwind with a drink in a comfortable setting. Alternatively, Hotel Hassler Roma offers a welcoming atmosphere for easing into the nightlife.

Take some time to reflect on your day and savor another beautiful night in Italy.

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Day 6

Day 6 – Rome - departure day

  • Rome - Departure day
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  • Altar of the Fatherland
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Day 6 of your road trip in Italy is your departure day. This is your chance to catch a last glimpse of Rome before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

Make the most of your final day in Italy by visiting Rome’s iconic markets and shopping establishments. Secure the perfect souvenirs for your family and friends back home or buy yourself a remembrance of your amazing experience in Italy.

A top pick for your self-guided sightseeing tour today is Altare Della Patria. Over 1,683,070 travelers visit this attraction every year. Previous visitors have rated this architectural structure an average of 4.8 out of 5 stars in 49,843 reviews.

Before you conclude your road trip in Italy, drop by another restaurant for a last chance at a memorable dining experience in Rome.

If you're in the mood for something new, try Maccheroni, another premier location with a delectable menu.

You’ll then say farewell to Rome. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Italy!

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