7-Day Italy Self-Drive Road Trip With Itinerary from Ancona to Rome, Florence, and Venice and surrounding area

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Experience the freedom of the open road in Italy as you embark on an unforgettable 7-day road trip! This experience caters to every traveler, featuring destinations like Ancona, Loreto, Serra San Quirico, Rome, Florence, Padua, Venice, Miramare / Miramar, and Trieste.

This perfectly planned road trip itinerary in Italy takes you through some of the best places to see in the country. You will spend 2 nights in Ancona, 1 night in Rome, 1 night in Florence, and 2 nights in Venice. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Italy. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have got you covered.

Upon arriving in Ancona, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Italy on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Italy. Trevi Fountain and Colosseum are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Pantheon, learn more about the unique Piazza Navona, and immerse yourself in the vibrant atmosphere of Piazza San Marco.

As you hit the open road and drive through Ancona, Loreto, Serra San Quirico, Rome, Florence, Padua, Venice, Miramare / Miramar, and Trieste, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Italy. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Italy.

Throughout your road trip in Italy, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Italy.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodation, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Italy fill up quickly, so book your spot early. Select a date and start planning your road trip in Italy today!

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Itinerary summary

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Days
Destination
Attractions
Overnight
Day
City & Overnight
Attractions
Passetto
Sanctuary of the Holy House of LoretoParco Naturale Regionale Gola della Rossa e di FrasassiFrasassi Caves
Roman ForumColosseumPantheonPiazza NavonaTrevi Fountain
The Basilica of St AnthonyPrato della VallePiazza dei Signori, PaduaScrovegni Chapel
Miramare CastleMolo AudaceUnity of Italy SquarePiazza della Borsa
Rialto BridgeDoge's PalacePiazza San MarcoSt Mark's Basilica
Piazza del Plebiscito

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Day 1

Day 1

  • Ancona - Arrival day
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  • Passetto
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Welcome to Ancona, the perfect starting point for your road trip in Italy! Pick up your rental car and let the adventure begin. You will spend 1 night immersing yourself in Ancona's charm before embarking on the next leg of your journey.

Ancona is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Passetto, or just taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

Make your way to your chosen hotel. Check-in typically starts between 2 and 4 PM in Ancona. Make yourself at home and enjoy some downtime before heading out again.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Ancona, it's often a good idea to reserve a table in advance.

Treat yourself to a delightful dinner at Playa Solero, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Zucchero a Velò? It's another excellent option with a diverse menu. Consider reserving a table at Ristorante Il Giardino as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Ancona.

Keep the excitement of the evening going by visiting a bar or two. Posa Bar is an excellent place to start. You could also check out Bar Four Roses, offering a different kind of charm. A last recommendation for the day is Amarillo Beer Bar Ancona. This bar promises an enjoyable experience with tasty drinks and a vibrant setting.

Raise a toast to the start of your 7-day road trip in Italy!

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Day 2

Day 2

  • Ancona
  • Rome
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Drive 368 km, 4 hours 46 min

  • Sanctuary of the Holy House of Loreto
  • Parco Naturale Regionale Gola della Rossa e di Frasassi
  • Frasassi Caves
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Dive into day 2 of your remarkable road trip in Italy. Today you will explore Loreto, Serra San Quirico, and San Vittore, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Rome. You’ll stay here for 1 night.

Bring your curiosity for today’s adventure around Ancona. Some of the town’s most loved attractions await! Sanctuary Of The Holy House Of Loreto is the perfect place to start. This church is one of the most interesting places to visit in Ancona. Next, head to Parco Naturale Regionale Gola Della Rossa E Di Frasassi, a locally appreciated nature reserve, known for its picturesque features.

In between the sights, don’t hesitate to take small detours to explore local stores and eateries. When you’re ready to continue your adventure, head to Frasassi Caves. This visually striking cave system is a highly recommended experience. Visit these for an interesting touch to your journey.

At the end of the day, you will drive to Rome, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As you explore more of Rome, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Treat yourself to an extraordinary dining experience at La Pergola, a 3-star Michelin restaurant offering an incredible mediterranean and contemporary menu. Alternatively, if your taste buds call for something different, Il Pagliaccio is one of the best restaurants for creative and innovative cuisine in Rome. This 2-star Michelin-awardee earns consistently high praises from guests. We also recommend checking out the menu at Enoteca La Torre. As a top-rated establishment with 2 Michelin star, it is an ideal choice for mediterranean and creative cuisine in the city.

After enjoying a fulfilling meal, continue your evening at La Botticella Of Poggi Giovanni, ideal for those looking to unwind with a drink in a comfortable setting. Alternatively, Almalu Trastevere offers a welcoming atmosphere for easing into the nightlife. Similarly, Bar Viminale Di Pepi Maurilio provides an excellent environment for a relaxed and enjoyable evening.

Get a good night's sleep and look forward to another great day on the road in Italy!

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Day 3

Day 3

  • Rome
  • Florence
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Drive 286 km, 3 hours 51 min

  • Roman Forum
  • Colosseum
  • Pantheon
  • Piazza Navona
  • Trevi Fountain
  • More

Embark on another extraordinary experience on day 3 of your road trip in Italy. Today, you will make 1 stop and experience some of the highlights of Rome. At the end of the day, you will enjoy the comforts of a top-rated hotel in Florence, which will be your home away from home for 1 night.

A blend of family-friendly attractions, breathtaking views, and picturesque spots await you in Rome on today’s itinerary. First up is the world-famous archeological site, Roman Forum. Afterward, continue to Colosseum, an archeological site every traveler should visit.

As you explore Rome’s charming streets, take in the lively atmosphere and get to know the character of the city. Next, make your way to Pantheon. This timeless monument is an essential stop. Following that, head to Piazza Navona, another must-visit site that will enhance your experience. Don’t forget to stop by Trevi Fountain, a world-famous monument in the city.

When you’re done exploring for the day, you’ll drive to your hotel in Florence. Check in and spend some time relaxing before you head out to tour the city.

As dinnertime approaches, it's time to head out for a bite to eat in Florence. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Get ready for an unforgettable culinary journey in Florence by reserving a table at Enoteca Pinchiorri. Renowned as a 3-star Michelin restaurant, it offers an exceptional italian contemporary menu. For a different taste experience, head to Santa Elisabetta, recognized for its delicious creative and mediterranean dishes. This 2-star Michelin restaurant consistently impresses guests, ensuring a memorable addition to your holiday. Looking for another option? Make sure to visit Gucci Osteria da Massimo Bottura, a local favorite known for its delightful italian contemporary and international cuisine in Florence. Nestled in the heart of the city, this restaurant with 1 Michelin star is an ideal choice for discerning italian contemporary and international foodies seeking culinary excellence.

Cap off your dinner by heading to Manifattura, ideal for a leisurely evening with a drink in hand. Se·sto On Arno Rooftop Bar is another bar that offers an enjoyable setting. Similarly, Il Vinile is also a popular place to go on a night out, perfect for relaxing and socializing.

Raise your glass to another unforgettable day in Italy!

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Day 4

Day 4

  • Florence
  • Venice
  • More

Drive 280 km, 3 hours 48 min

  • The Basilica of St Anthony
  • Prato della Valle
  • Piazza dei Signori, Padua
  • Scrovegni Chapel
  • More

On day 4 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 1 destination, Padua. When you’re not sightseeing, take time to relax at your selected hotel in Venice, where you’ll be staying for 2 nights.

Florence is home to plenty of attractions that offer family-friendly attractions, photo-friendly spots, and historic treasures! Start at The Basilica Of St. Anthony, a captivating church that is worthwhile a visit in the city. Nearby, you’ll find Prato Della Valle, enchanting visitors with its enchanting appeal. Continue your exploration at Piazza Dei Signori, Padua. This public square is one of the city’s most notable spots.

Enjoy the freedom of exploring Florence at your own pace and find hidden gems along the way. If you want to see more picture-perfect spots, make sure to visit Scrovegni Chapel.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Venice. Venice offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

Indulge in a memorable dining experience at one of Venice's most popular restaurants, and connect with friendly locals for an authentic adventure.

Enjoy an outstanding dining experience at Local, a 1-star Michelin restaurant offering an exceptional contemporary menu. Alternatively, if you're in the mood for something different, consider the nearby 1-star Michelin-awardee, Wistèria, known for its delicious contemporary and venetian cuisine. Another highly-recommended place to eat in Venice is Quadri, a renowned restaurant with a 1-star Guide Michelin recognition and a delicious modern menu.

Explore the vibrant nightlife at Al Parlamento after your meal, a hub for lively evenings and memorable moments. Or, head to The Caffe Rosso for a great selection of flavorful drinks and a charming setting. Furthermore, Adagio is perfect for those looking to extend their night with a touch of local flavor.

Relax and recharge in preparation for another adventurous day in Italy!

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Day 5

Day 5

  • Venice
  • More

Drive 318 km, 4 hours 9 min

  • Miramare Castle
  • Molo Audace
  • Unity of Italy Square
  • Piazza della Borsa
  • More

Greet day 5 of your road trip in Italy with a smile and start your day with a hearty breakfast. You will return to Venice for your remaining 1 night in the city later today, but first, it’s time for some exploring! On the agenda for this day, you’ll find only the best things to see and do in Miramare / Miramar and Trieste.

Enjoy the perfect balance of relaxation and exploration in Venice today. One of the most well-known attractions included on the itinerary is Miramare Castle. This romantic castle will help you start your sightseeing on top. Then, take a leisurely stroll to Molo Audace and learn what makes this enchanting pier unique.

Throughout the day, make sure to take breaks to appreciate the surroundings. Next up, visit the interesting Piazza Unità D'italia. After exploring the public square, head to Piazza Della Borsa. This often recommended public square is a highlight in Venice.

When you’re done exploring for the day, you’ll return to Venice and your accommodation.

Indulge in a memorable dining experience at one of Venice's most popular restaurants, and connect with friendly locals for an authentic adventure.

Dine in style at Generator Venice, a top recommendation for dinner tonight. Or, for a change of pace, Nevodi boasts a menu that's sure to impress. Also, be sure to check out Ristorante La Piazza. Known as a local hotspot, it’s a great choice for tonight in Venice.

After your meal, keep the night alive at a bar like Il Mercante, known for its lively atmosphere. The Irish Pub Venezia is another top recommendation that provides the perfect setting with well-crafted drinks and a welcoming ambiance. Similarly, Ai Stagneri offers an excellent atmosphere for those looking to amp up the evening.

Take some time to reflect on your day and savor another beautiful night in Italy.

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Day 6

Day 6

  • Venice
  • Ancona
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Drive 365 km, 3 hours 55 min

  • Rialto Bridge
  • Doge's Palace
  • Piazza San Marco
  • St Mark's Basilica
  • More

On day 6 of your road trip in Italy, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Venice. In the evening, you’ll end up in Ancona, where you will stay for 1 night.

Start by visiting Rialto Bridge, a prime spot to begin your journey. This majestic historical landmark is sure to impress. Next on your list is Doge's Palace, another must-visit landmark and captivating palace renowned for its culturally significant features.

While exploring and sightseeing, take time to savor the culture of Venice by sampling some local delicacies. When you’re ready for more sightseeing, head to Piazza San Marco. This visually striking public square is an essential place to visit for anyone looking for the full Venice experience. We also recommend visiting St Mark's Basilica, a well-known church.

At the end of the day, you will drive to Ancona, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Ancona. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Experience a symphony of flavors at Sot'Ajarchi in Ancona by securing a reservation in advance. Renowned for its Bib Gourmand distinction, Sot'Ajarchi delights its guests with its exceptional variety of meals showcasing delicious seafood and from the marches cuisine. Or, if you're feeling adventurous, why not try Bontà delle Marche? It's another excellent option with a diverse menu.

After your delicious meal, get a taste of the vibrant nightlife with a visit to Alla Tazza D'oro, known for its inviting atmosphere.

Savor another day of unforgettable experiences in Italy!

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Day 7

Day 7

  • Ancona - Departure day
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  • Piazza del Plebiscito
  • More

Day 7 of your road trip in Italy is your departure day. This is your chance to catch a last glimpse of Ancona before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, begin at Piazza Del Plebiscito. This curiosity-inducing public square is a popular place to see in the city.

Explore local shops for souvenirs to remember your trip or find unique gifts for loved ones.

Before you conclude your road trip in Italy, drop by another restaurant for a last chance at a memorable dining experience in Ancona.

Treat yourself to a delicious dinner at Pizzeria Pulcinella, an excellent option for tonight's dining. Looking for something different? Donegal Irish Pub offers a tantalizing alternative with its diverse menu. And don’t miss Vino E Cucina Miscia.

You’ll then say farewell to Ancona. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Italy!

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