7-Day Italy Road Trip from Perugia traveling south to Rome, and Siena

On day 2 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 1 destination, Perugia. When you’re not sightseeing, take time to relax at your selected hotel in Rome, where you’ll be staying for 3 nights.

Be one of the day’s first visitors at Carducci Gardens. This park is rated an average of 4.5 out of 5 stars by 1,768 visitors.

When you’re finished at Carducci Gardens, head to Porta Marzia. This one-of-a-kind city gate is rated an average of 4.6 out of 5 stars in 119 reviews.

Beyond the above-mentioned attractions, you also have the opportunity to visit Rocca Paolina. This rocca is rated an average of 4.7 out of 5 stars by 7,128 visitors.

If you’re keen to explore more, then consider a visit to National Archaeological Museum Of Umbria. This museum is a much-appreciated attraction with an average rating of 4.5 out of 5 stars from 669 visitors.

At the end of the day, you will drive to Rome, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As dinnertime approaches, it's time to head out for a bite to eat in Rome. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Experience a taste of local culinary excellence while in Rome by securing a table at La Pergola. An esteemed 3-star Michelin restaurant, it features an exceptional mediterranean, and contemporary menu. For an alternative taste experience, visit Il Pagliaccio, famous for its scrumptious creative, and innovative dishes. This 2-star Michelin venue consistently impresses guests, making it a standout addition to your holiday plans. Looking for another choice? Discover Enoteca La Torre, a local favorite celebrated for its exquisite mediterranean, and creative cuisine in Rome. Located in the heart of the city, this 2-star Michelin restaurant is an ideal pick for mediterranean, and creative cuisine lovers seeking top-notch culinary experiences.

After savoring a delicious meal, step into the vibrant nightlife at La Botticella Of Poggi Giovanni, where the evening is just getting started. In the same way, Sant' Eustachio Caffè offers a unique charm perfect for experiencing the local bar scene in Rome. Caffè Portofino is another top-recommended bar that is sure to get you into the mood for some dancing and celebrating.

Raise your glass to another unforgettable day in Italy!

Day 3 of your road trip across Italy promises a magnificent time exploring Rome. You have 2 nights left in Rome. Take the opportunity to experience more of the best attractions and activities in the city.

A top pick for your self-guided sightseeing tour today is Colosseum. Over 7,400,000 travelers visit this attraction every year. Previous visitors have rated this roman amphitheatre an average of 4.7 out of 5 stars in 328,821 reviews.

Roman Forum is a local recommendation that you also can pay a visit today. This square is rated an average of 4.7 out of 5 stars in 114,450 reviews.

Another attraction you won't want to miss is Pantheon. This roman temple is rated an average of 4.8 out of 5 stars in 189,682 reviews. Every year, around 30,000,000 travelers visit this site to discover its unique features.

Piazza Navona is another outstanding experience in Rome. Around 158,771 travelers have rated this square an average of 4.7 out of 5 stars.

If you long for more, Castel Sant'angelo is not far away. This museum is a lovely addition to your itinerary. Previous visitors have rated it an average of 4.7 out of 5 stars in 72,431 reviews.

Don’t forget to check out all the popular tours and activities you can add to your travel plan. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Rome. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Don’t miss out on dining at DEROMA - Farine Romane, a top-rated dining destination in Rome. If you're in the mood to try something new, consider La Taverna Italiana, another top spot with a mouthwatering menu. You might also want to secure a reservation at Centro. With a reputation for consistently satisfied customers, it’s a perfect choice to enhance your stay in Rome this evening.

Continue the enjoyment post-dinner at The Apartment Bar Roma, a cherished local gathering spot renowned for its welcoming atmosphere. Similarly, Hotel Hassler Roma offers a vibrant space for indulging in well-crafted drinks and engaging conversation.

Raise your glass and celebrate another amazing day of your road trip in Italy!

Day 4 of your road trip will take you to the best attractions Rome has to offer. Cherish the 1 night you have left in Rome by discovering the best things there are to see and do in the city.

Take the opportunity to see Trevi Fountain. This attraction has an average rating of 4.8 out of 5 stars from 343,494 visitors.

Piazza Di Spagna is another sightseeing hotspot in the area. This square has been rated an average of 4.7 out of 5 stars by 113,658 travelers.

Rome is also the home of Spanish Steps. Around 57,211 people have rated this monumental staircase an average of 4.5 out of 5 stars.

Another place you’ll want to visit is Piazza Del Popolo. With an average rating of 4.6 out of 5 stars from a total of 89,807 reviews, a visit to this square is a great idea.

This day of your vacation in Rome is also your chance to admire Villa Borghese. This must-visit urban zone of rome enjoys an average rating of 4.6 out of 5 stars from 69,749 reviews.

To immerse yourself in more memorable moments in Rome, check out the best-rated tours the region offers. You can discover and choose from all of the top-rated activities you can do on this day in Rome below.

After a day of adventure, treat yourself to an exquisite dinner at one of Rome's best restaurants.

Have a fantastic dining experience at Ristorante Tema, a highly recommended choice for tonight's dinner. If you're looking to mix things up, Maccheroni offers an enticing alternative with its varied menu. Additionally, RoYaL Art Cafè Roma is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Rome.

Relax and recharge in preparation for another adventurous day in Italy!

Embark on another extraordinary experience on day 5 of your road trip in Italy. Today, you will make 1 stop and experience some of the highlights of Vatican City. At the end of the day, you will enjoy the comforts of a top-rated hotel in Siena, which will be your home away from home for 1 night.

When you’re ready to jump back into the car and say goodbye to Rome, you’ll hit the road in the direction of Vatican City, Vatican City. Witness the landscapes transform as you cross the border to Vatican City. This drive usually takes around 11 min. When you arrive, enjoy some sightseeing.

Seize the day by visiting some of the best attractions in the area, like St. Peter's Basilica. This extraordinary major basilica has an average rating of 4.8 out of 5 stars from 131,043 visitors. Each year, around 11,000,000 people visit this remarkable site to admire its features and learn more about it.

Next, make your way to Sistine Chapel. This chapel is rated an average of 4.7 out of 5 stars in 52,083 reviews.

While in Vatican City, we also recommend a visit to Saint Peter's Square. This square has been rated an average of 4.8 out of 5 stars in 38,954 reviews.

If you’re keen to explore even more, then consider a visit to Vatican Museums. This attraction gets around 1,612,530 yearly visitors. With an average rating of 4.6 out of 5 stars by 133,310 travelers, this art museum is a highly recommended stop on your sightseeing around Vatican City.

When you’re done exploring for the day, you’ll drive to Siena, where you'll have a hotel waiting for you. Check in and spend some time relaxing before you head out to explore the city.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Siena. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Treat yourself to a delightful dinner at Antica Trattoria Papei, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Osteria Quattro Venti? It's another excellent option with a diverse menu. Consider reserving a table at Osteria da Divo as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Siena.

After your meal, keep the night alive at a bar like Meet Life Cafè, known for its lively atmosphere. Maudit Pub is another top recommendation that provides the perfect setting with well-crafted drinks and a welcoming ambiance. Similarly, Bar Impero Siena offers an excellent atmosphere for those looking to amp up the evening.

Take some time to reflect on your day and savor another beautiful night in Italy.

Experience an unparalleled adventure on day 6 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 2 vibrant destinations - Siena, and Santa Maria degli Angeli. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Perugia. You will spend 1 night here for some well-deserved relaxation.

Take the opportunity to see Piazza Del Campo. This attraction has an average rating of 4.8 out of 5 stars from 64,175 visitors.

Siena Cathedral is another sightseeing hotspot in the area. This domus has been rated an average of 4.8 out of 5 stars by 21,656 travelers.

Continue your road trip and head to your next destination, Santa Maria degli Angeli. This car ride takes around 1 hour 38 min.

Begin your sightseeing with a visit to Basilica Of San Francesco D'assisi. This extraordinary papal basilica is rated an average of 4.9 out of 5 stars by 33,258 visitors.

After soaking up all the sights of today's itinerary, you'll be ready to hit the road in the direction of your accommodation in Perugia. Perugia offers plenty of top-rated hotels and other places to stay on any travel budget. Take some time to relax before you head out to explore.

As you explore more of Perugia, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Savor the flavors at Ristorante del Sole, a top pick for dinner tonight. Alternatively, Al Mangiar Bene beckons with its unique menu offerings. Also, consider Elfo Pub Perugia. With its consistent customer satisfaction, it’s an excellent option for dining in Perugia tonight.

Cap off your culinary experience with a visit to some of the most celebrated bars in the area. For instance, Caffè Fortebraccio stands out as an excellent choice for a post-dinner cocktail. Alternatively, Caffe Del Banco offers an ideal atmosphere to enjoy the pleasures of the night. Dempsey's Perugia is also a great option that provides a perfect setting for a relaxing evening.

Relax and recharge in preparation for another adventurous day in Italy!