One-Week Italy Road Trip from Rome traveling west to Arezzo, Florence, and Perugia

Day 2 offers a multitude of experiences. You will stay in Rome for 1 night more, offering you enough time to explore at a relaxed pace.

Drop by the renowned Castel Sant'angelo. This popular museum has been rated an average of 4.7 out of 5 stars by 72,431 visitors. Based on recent data, this attraction is visited by more than 918,591 travelers every year.

Another unforgettable place to experience is Piazza Di Spagna. Rated 4.7 out of 5 stars by 113,658 visitors, this square deserves a spot on today's sightseeing itinerary.

We also recommend a visit to Trevi Fountain. This sculpture has been rated an average of 4.8 out of 5 stars in 343,494 reviews.

Another favorite attraction in the area is Roman Forum. This square and popular place of interest enjoys a rating of 4.7 out of 5 stars from 114,450 local and international travelers.

If you’re keen to explore even more, then consider a visit to Colosseum. This roman amphitheatre gets around 7,400,000 annual visitors. With an average rating of 4.7 out of 5 stars from 328,821 travelers, this roman amphitheatre is an attraction many avid travelers highly recommend visiting while in Rome.

If you have an appetite for more adventure, check out the fantastic selection of tours and tickets offered in Rome on this day of your trip. You'll find the most recommended ones below.

After a day of adventure, treat yourself to an exquisite dinner at one of Rome's best restaurants.

Start your culinary exploration in Rome by securing a reservation at La Pergola. This renowned restaurant holds 3 Michelin star and offers an exceptional menu of mediterranean, and contemporary cuisine. For another dining delight, visit Il Pagliaccio, celebrated for its delectable creative, and innovative menu. This acclaimed 2-star Michelin-recipient consistently leaves guests satisfied, making it a must-visit during your holiday. Looking for a different experience? Discover Enoteca La Torre, a top local spot known for its tantalizing mediterranean, and creative menu. With a 2-star Michelin recognition, it guarantees an exceptional dining adventure.

Continue your evening by exploring the vibrant nightlife scene at The Apartment Bar Roma, a prime destination for a thrilling night out. Also, don’t forget to check out Hotel Hassler Roma, a bar that offers unique local touches.

Raise your glass and celebrate another amazing day of your road trip in Italy!

On day 3 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 2 destinations, Rome, and Vatican City. When you’re not sightseeing, take time to relax at your selected hotel in Arezzo, where you’ll be staying for 1 night.

Begin your sightseeing with a visit to Pantheon. This roman temple gets 30,000,000 visitors each year and is rated an average of 4.8 out of 5 stars in 189,682 reviews.

When you’re ready to jump back into the car and say goodbye to Rome, you’ll hit the road in the direction of Vatican City, Vatican City. Witness the landscapes transform as you cross the border to Vatican City. This drive usually takes around 11 min. When you arrive, enjoy some sightseeing.

Be one of the day’s first visitors at St. Peter's Basilica. This major basilica is rated an average of 4.8 out of 5 stars by 131,043 visitors. Attracting more than 11,000,000 yearly visitors, it’s a top sight you don’t want to miss.

When you’re finished at St. Peter's Basilica, head to Sistine Chapel. This one-of-a-kind chapel is rated an average of 4.7 out of 5 stars in 52,083 reviews.

Beyond the above-mentioned attractions, you also have the opportunity to visit Vatican Museums. This art museum is rated an average of 4.6 out of 5 stars by 133,310 visitors. Visiting Vatican Museums means you'll be one of 1,612,530 people who do so every year.

At the end of the day, you will drive to Arezzo, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

After a day of adventure, treat yourself to an exquisite dinner at one of Arezzo's best restaurants.

Experience a harmony of flavors at Octavin in Arezzo by securing a reservation in advance. Known for its 1-star Michelin status, Octavin offers a delightful variety of dishes highlighting its delicious creative menu. If you're looking to mix things up, La Clandestina offers an enticing alternative with its varied menu.

Round off your dining experience by visiting Liquid Bar, a prime location for a drink.

Take some time to reflect on your day and savor another beautiful night in Italy.

Experience an unparalleled adventure on day 4 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 2 vibrant destinations - Pisa, and Lucca. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Florence. You will spend 2 nights here for some well-deserved relaxation.

After soaking in Arezzo’s unique atmosphere, jump into the car with a full heart and drive in the direction of your next destination: Pisa. Expect your car journey to take a minimum of 1 hour 56 min. When you arrive in Pisa, it's time to take a break from the road.

A top pick for your self-guided sightseeing tour today is Leaning Tower Of Pisa. Over 3,200,000 travelers visit this attraction every year. Previous visitors have rated this bell tower an average of 4.7 out of 5 stars in 116,882 reviews.

Piazza Del Duomo, Pisa is a local recommendation that you also can pay a visit today. This square is rated an average of 4.7 out of 5 stars in 104,550 reviews.

Another attraction you won't want to miss is Pisa Cathedral. This cathedral is rated an average of 4.8 out of 5 stars in 8,361 reviews.

Embrace the thrill of the open road as you wave goodbye to Pisa and set your GPS to Lucca. While on the road, immerse yourself in your favorite road trip tunes or sample the sounds from a local radio station. This car ride usually takes around 31 min. Upon reaching Lucca, unwind, observe, and explore. The best things to do, see, and eat are waiting for you.

Seize the day by visiting some of the best attractions in the area, like Piazza Dell'anfiteatro. This extraordinary square has an average rating of 4.6 out of 5 stars from 24,190 visitors.

When you’re done exploring for the day, you’ll drive to Florence, where you'll have a hotel waiting for you. Check in and spend some time relaxing before you head out to explore the city.

As dinnertime approaches, it's time to head out for a bite to eat in Florence. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Experience a symphony of flavors at Enoteca Pinchiorri in Florence by securing a reservation in advance. Renowned for its 3-star Michelin distinction, Enoteca Pinchiorri delights its guests with its exceptional variety of meals showcasing delicious italian contemporary cuisine. For a palate-pleasing alternative, make sure to dine at Santa Elisabetta, acclaimed for its delectable creative, and mediterranean specialties. This local 2-star Michelin establishment consistently satisfies guests, ensuring an unforgettable holiday experience. Want to go on another culinary journey? Delight your senses at Gucci Osteria da Massimo Bottura, a top-rated restaurant known for its outstanding menu. Known as a top-rated 1-star Michelin establishment, it's a top choice for italian contemporary, and international cuisine in the city.

After your meal, keep the night alive at a bar like Manifattura, known for its lively atmosphere. Se·sto On Arno Rooftop Bar is another top recommendation that provides the perfect setting with well-crafted drinks and a welcoming ambiance. Similarly, Archea Brewery offers an excellent atmosphere for those looking to amp up the evening.

Raise your glass and celebrate another amazing day of your road trip in Italy!

Greet day 5 of your road trip in Italy with a smile and start your day with a hearty breakfast. You will return to Florence for your remaining 1 night in the city later today, but first, it’s time for some exploring! On the agenda for this day, you’ll find only the best things to see and do in Siena, and Florence.

Be one of the day’s first visitors at The Boboli Gardens. This park is rated an average of 4.2 out of 5 stars by 25,341 visitors.

When you’re finished at The Boboli Gardens, head to Galleria Dell'accademia. This one-of-a-kind national museum is rated an average of 4.6 out of 5 stars in 34,429 reviews. Every year, approximately 1,719,645 travelers come here to experience the national museum for themselves.

Beyond the above-mentioned attractions, you also have the opportunity to visit Central Market. This sightseeing destination is rated an average of 4.4 out of 5 stars by 43,100 visitors.

Continue your road trip and head to your next destination, Siena. This car ride takes around 1 hour 16 min.

When you’re ready for some sightseeing, make your way to Piazza Del Campo. This much-appreciated square is rated 4.8 out of 5 stars in 64,175 reviews.

Next up is Siena Cathedral. This domus has an average rating of 4.8 out of 5 stars from 21,656 visitors.

When you’re done exploring for the day, you’ll return to Florence and your accommodation.

After a day of adventure, treat yourself to an exquisite dinner at one of Florence's best restaurants.

Enjoy a delicious meal at Trattoria Da Burde, a top-rated dining destination in Florence. If you're in the mood to try something new, consider Ristorante Buca Mario, another top spot with a mouthwatering menu. You might also want to secure a reservation at Eataly Firenze. With a reputation for consistently satisfied customers, it’s a perfect choice to enhance your stay in Florence this evening.

Relax and recharge in preparation for another adventurous day in Italy!

Embark on another extraordinary experience on day 6 of your road trip in Italy. Today, you will make 1 stop and experience some of the highlights of Florence. At the end of the day, you will enjoy the comforts of a top-rated hotel in Perugia, which will be your home away from home for 1 night.

Drop by the renowned Piazza Della Signoria. This popular square has been rated an average of 4.8 out of 5 stars by 66,956 visitors.

Another unforgettable place to experience is Cathedral Of Santa Maria Del Fiore. Rated 4.8 out of 5 stars by 76,359 visitors, this church deserves a spot on today's sightseeing itinerary.

We also recommend a visit to Ponte Vecchio. This deck arch bridge has been rated an average of 4.7 out of 5 stars in 118,099 reviews.

Another favorite attraction in the area is Uffizi Gallery, drawing over 2,011,219 yearly visitors. This national museum and popular place of interest enjoys a rating of 4.7 out of 5 stars from 61,794 local and international travelers.

If you’re keen to explore even more, then consider a visit to Piazzale Michelangelo. With an average rating of 4.8 out of 5 stars from 77,744 travelers, this square is an attraction many avid travelers highly recommend visiting while in Florence.

After soaking up all the sights of today's itinerary, you'll be ready to hit the road in the direction of your accommodation in Perugia. Perugia offers plenty of top-rated hotels and other places to stay on any travel budget. Take some time to relax before you head out to explore.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Perugia. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Make sure to reserve a table at Ristorante Settimo Sigillo, an iconic dining spot in Perugia. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Bar Pellas, a popular restaurant in Perugia. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of La Taverna, a hidden gem nestled in Perugia. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Cap off your culinary experience with a visit to some of the most celebrated bars in the area. For instance, Tommi Bar stands out as an excellent choice for a post-dinner cocktail. Alternatively, Valentina offers an ideal atmosphere to enjoy the pleasures of the night. Caffe Dal Perugino is also a great option that provides a perfect setting for a relaxing evening.

As the sun sets on another day of adventure, rest up and recharge for the next leg of your road trip in Italy.

Dive into day 7 of your remarkable road trip in Italy. Today you will explore Santa Maria degli Angeli, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Rome. You’ll stay here for 1 night.

Santa Maria degli Angeli’s wonders await as you prepare for another journey on the road, leaving the breathtaking surroundings of Perugia behind. This drive usually takes around 32 min. Santa Maria degli Angeli welcomes you with a multitude of unique vacation experiences.

When you’re ready for some sightseeing, make your way to Basilica Of San Francesco D'assisi. This much-appreciated papal basilica is rated 4.9 out of 5 stars in 33,258 reviews.

Next up is Piazza Del Comune. This point of interest has an average rating of 4.6 out of 5 stars from 3,057 visitors.

Another top sightseeing recommendation is Basilica Di Santa Chiara. This minor basilica has been rated 4.7 out of 5 stars in 9,628 reviews.

Santa Maria degli Angeli’s wonders await as you prepare for another journey on the road, leaving the breathtaking surroundings of Santa Maria degli Angeli behind. This drive usually takes around 11 min. Santa Maria degli Angeli welcomes you with a multitude of unique vacation experiences.

Start your sightseeing with a visit to Basilica Of Santa Maria Degli Angeli. This papal basilica is rated an average of 4.8 out of 5 stars from 19,258 visitors.

At the end of the day, you will drive to Rome, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

Indulge in a memorable dining experience at one of Rome's most popular restaurants, and connect with friendly locals for an authentic adventure.

Enjoy a delicious meal at Ristorante Tema, a top-rated dining destination in Rome. If you're in the mood to try something new, consider Maccheroni, another top spot with a mouthwatering menu. You might also want to secure a reservation at RoYaL Art Cafè Roma. With a reputation for consistently satisfied customers, it’s a perfect choice to enhance your stay in Rome this evening.

Relax and recharge in preparation for another adventurous day in Italy!