9-Day Italy Road Trip from Florence to Siena, Perugia, and Rome

Say hello to Florence! Your exciting road trip through Italy is just about to start. Navigating the top places to see in the region is a breeze with a car. The rental vehicle of your choice will be ready for pickup upon your arrival in the city. You will stay in Florence for 2 nights before you continue your adventure!

Florence is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Central Market or taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

Make your way to your chosen hotel. Check-in typically starts between 2 and 4 PM in Florence. Make yourself at home and enjoy some downtime before heading out again.

As dinnertime approaches, it's time to head out for a bite to eat in Florence. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Set out on a gastronomic journey in Florence by reserving a table at Enoteca Pinchiorri. Renowned for its , this restaurant presents an outstanding menu of italian contemporary cuisine. For a different taste, head over to Santa Elisabetta, renowned for its delectable creative and mediterranean dishes. This distinguished 2-star Michelin-recipient is a favorite among guests, making it a worthy addition to your holiday plans. Craving more culinary excitement? Explore Gucci Osteria da Massimo Bottura, a highly rated local gem known for its exquisite italian contemporary and international menu. With a 1-star Michelin acclaim, it promises a dining experience you won't want to miss. With its reputation for pleasing customers, it’s a fantastic choice for tonight in Florence.

Cap off your culinary experience with a visit to some of the most celebrated bars in the area. For instance, Manifattura stands out as an excellent choice for a post-dinner cocktail. Alternatively, SE·STO on Arno Rooftop Bar offers an ideal atmosphere to enjoy the pleasures of the night. Archea Brewery is also a great option that provides a perfect setting for a relaxing evening.

Raise a toast to the start of your 9-day road trip in Italy!

Day 2 of your road trip across Italy promises a magnificent time exploring Florence. You have 1 night left in Florence. Take the opportunity to experience more of the best attractions and activities in the city.

Start your sightseeing with a visit to Ponte Vecchio. This deck arch bridge is a popular stop on travelers’ itineraries in Florence, with an average rating of 4.7 out of 5 stars by 118,099 visitors.

Uffizi Gallery is another popular place of interest you can visit today. The average rating of 4.7 out of 5 stars from 61,794 reviews gives you an idea of other visitors’ experience at this attraction. It’s estimated that around 2,011,219 people visit this national museum every year.

If it’s still bright and early, make your way to piazza della Signoria. Visitors have rated this square an average of 4.8 out of 5 stars in 66,956 reviews.

Piazza della Repubblica is another unique site you can experience today. This attraction is a square rated an average of 4.6 out of 5 stars in 22,356 reviews.

Make your way to the fantastic Cathedral of Santa Maria del Fiore, perhaps the most famous church in Florence. This attraction is rated 4.8 out of 5 stars by 76,359 travelers.

Your discoveries in Florence do not have to stop there. Check out the fantastic selection of tours and tickets offered in Florence on this day of your trip. You can select your tours below.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Florence.

This renowned restaurant holds , and offers an exceptional menu of cuisine. Make sure to reserve a table at Trattoria Da Burde, an iconic dining spot in Florence. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Ristorante Buca Mario, a popular restaurant in Florence. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Eataly Firenze, a hidden gem nestled in Florence. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Raise your glass and celebrate another amazing day of your road trip in Italy!

On day 3 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 2 destinations, Florence and Pisa. When you’re not sightseeing, take time to relax at your selected hotel in Siena, where you’ll be staying for 1 night.

Journey into the unknown at Basilica of Santa Croce in Florence, a unique attraction awaiting your visit. This remarkable church has an average rating of 4.7 out of 5 stars from 28,544 reviews.

When you’re ready to continue your sightseeing, Galleria dell'Accademia is a recommended place to visit. This national museum is rated an average of 4.6 out of 5 stars in 34,429 reviews. Based on recent data, the attraction hosts 1,719,645 visitors per year.

As you’ve unraveled the marvels of Florence, it’s time to gear up for the next part of your road trip adventure. Under favorable conditions, your drive to Pisa may take around 1 hour 23 min. Upon your arrival in Pisa, you’ll be greeted with the opportunity to do some sightseeing and exploring.

When you're ready to see some sights, Leaning Tower of Pisa is a great place to start. This bell tower is rated an average of 4.7 out of 5 stars by 116,882 visitors. Leaning Tower of Pisa attracts more than 3,200,000 visitors every year.

Another popular attraction you can visit today is Piazza del Duomo, Pisa. This square has an average rating of 4.7 out of 5 stars from 104,550 travelers.

After soaking up all the sights of today's itinerary, you'll be ready to hit the road in the direction of Siena. Siena offers plenty of top-rated hotels and other places to stay on any travel budget. Check in at the hotel of your choice and take some time to relax before you head out to explore.

Indulge in a memorable dining experience at one of Siena's most popular restaurants, and connect with friendly locals for an authentic adventure.

Enjoy a delicious meal at Antica Trattoria Papei, a top-rated dining destination in Siena. If you're in the mood to try something new, consider Osteria Quattro Venti, another top spot with a mouthwatering menu. You might also want to secure a reservation at Osteria da Divo. With a reputation for consistently satisfied customers, it’s a perfect choice to enhance your stay in Siena this evening.

Explore the vibrant nightlife at Meet Life Cafè after your meal, a hub for lively evenings and memorable moments. Or, head to Maudit Pub for a great selection of flavorful drinks and a charming setting. Furthermore, Bar Impero Siena is perfect for those looking to extend their night with a touch of local flavor.

Get a good night's sleep and look forward to another great day on the road in Italy!

Experience an unparalleled adventure on day 4 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 2 vibrant destinations - Siena and Santa Maria degli Angeli. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Perugia. You will spend 1 night here for some well-deserved relaxation.

Make piazza del Campo your first stop of the day. Previous visitors have rated this square an average of 4.8 out of 5 stars in 64,175 reviews.

Next up, make a stop at Siena Cathedral. With an average rating of 4.8 out of 5 stars by 21,656 visitors, it's easy to understand why so many people visit this domus every year.

When you’re ready to jump back into the car and say goodbye to Siena, you’ll hit the road in the direction of Santa Maria degli Angeli. This drive usually takes around 1 hour 38 min. When you arrive, enjoy some sightseeing.

A top pick for your self-guided sightseeing tour today is Basilica of San Francesco d'Assisi. Previous visitors have rated this papal basilica an average of 4.9 out of 5 stars in 33,258 reviews.

At the end of the day, you will drive to Perugia, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Perugia. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Savor the flavors at Ristorante Settimo Sigillo, a top pick for dinner tonight. Alternatively, Bar Pellas beckons with its unique menu offerings. Also, consider La Taverna. With its consistent customer satisfaction, it’s an excellent option for dining in Perugia tonight.

Continue your evening by exploring the vibrant nightlife scene at Tommi Bar, a prime destination for a thrilling night out. Also, don’t forget to check out Valentina, a bar that offers unique local touches. Likewise, Caffe Dal Perugino provides an excellent alternative for a fun evening.

Relax and recharge in preparation for another adventurous day in Italy!

On day 5 of your road trip in Italy, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Vatican City. In the evening, you’ll end up in Rome, where you will stay for 3 nights.

Fasten your seatbelt and make your way to your next stop. Vatican City, home to many well-known sights in the region, is a lovely destination on today’s itinerary. Upon arrival in Vatican City, we highly recommend checking out some of the top attractions.

Journey into the unknown at Vatican Museums, a unique attraction awaiting your visit. This remarkable art museum has an average rating of 4.6 out of 5 stars from 133,310 reviews. Every year, Vatican Museums welcomes more than 1,612,530 curious visitors.

When you’re ready to continue your sightseeing, Saint Peter's Square is a recommended place to visit. This square is rated an average of 4.8 out of 5 stars in 38,954 reviews.

Another must-see attraction in Vatican City is Sistine Chapel. Rated an average of 4.7 out of 5 stars by 52,083 travelers, this popular tourist destination in Vatican City offers an experience you will remember.

St. Peter's Basilica is another popular stop on travelers' itineraries in Vatican City. This major basilica promises memorable moments of exploring. Other travelers have rated this attraction 4.8 out of 5 stars in 131,043 reviews. Each year, approximately 11,000,000 people travel to visit St. Peter's Basilica.

When you’re done exploring for the day, you’ll drive to Rome, where you'll have a hotel waiting for you. Check in and spend some time relaxing before you head out to explore the city.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Rome.

Start your culinary exploration in Rome by securing a reservation at La Pergola. This renowned restaurant holds , and offers an exceptional menu of mediterranean and contemporary cuisine. For another dining delight, visit Il Pagliaccio, celebrated for its delectable creative and innovative menu. This acclaimed 2-star Michelin-recipient consistently leaves guests satisfied, making it a must-visit during your holiday. Looking for a different experience? Discover Enoteca La Torre, a top local spot known for its tantalizing mediterranean and creative menu. With a 2-star Michelin recognition, it guarantees an exceptional dining adventure.

Unwind after your meal by stepping into La Botticella of Poggi Giovanni. This venue is celebrated for its extensive drink selections and cozy vibes. Alternatively, Sant' Eustachio Caffè offers a dynamic and energetic atmosphere for a glass or two. Don’t overlook Caffè Portofino, another top-rated bar in the area.

Raise your glass to another unforgettable day in Italy!

On day 6 of your road trip, you will have an entire day to explore Rome. You’ll stay in Rome for 2 nights and discover all the best things to see and do in the area.

Your sightseeing of the day begins at Spanish Steps, a remarkable monumental staircase where it’s easy to get lost in exploration. This top attraction is rated an average of 4.5 out of 5 stars in 57,211 reviews.

Next, satisfy your wanderlust at Piazza di Spagna. This square has an average rating of 4.7 out of 5 stars from 113,658 travelers.

Basilica di Santa Maria Maggiore is another must-visit attraction. This renowned major basilica offers a memorable experience, well worth a stop on your self-guided sightseeing tour. Rated 4.8 out of 5 stars by 27,678 travelers, it's one of the more popular places to see in the area.

Beyond the above-mentioned sites, you also have the opportunity to visit Colosseum. This well-loved roman amphitheatre boasts a 4.7 out of 5-star rating from 328,821 reviews. In a single year, approximately 7,400,000 visitors add this sightseeing spot to their travel itineraries.

When there’s still energy left for exploring, Roman Forum awaits. If you’ve been interested in experiencing a square, this is a top pick rated 4.7 out of 5 stars by 114,450 previous visitors.

Immerse yourself in the local scene through top-rated tours and activities. You can choose from a wide variety of easy to challenging tours and easily add them to your travel package below.

Indulge in a memorable dining experience at one of Rome's most popular restaurants, and connect with friendly locals for an authentic adventure.

Make sure to book a table at DEROMA - Farine Romane, a popular restaurant in Rome. This acclaimed restaurant and its mouthwatering dishes have earned the admiration of countless food lovers. Alternatively, experience a taste of Rome at La Taverna Italiana, a popular local restaurant. With a menu designed to impress, it promises a journey of flavors that will leave you captivated. Another top-rated restaurant to try is Centro. As a dining spot that gains consistently high praise from guests, it’s an ideal choice to enhance your time to Rome tonight.

After enjoying a delightful dinner, why not delve into the vibrant local bar scene? You might want to spend the evening at The Apartment Bar Roma, a well-loved spot among locals and tourists. Or, head to Hotel Hassler Roma. This bar boasts a welcoming environment that is perfect for winding down.

Get a good night's sleep and look forward to another great day on the road in Italy!

Day 7 of your road trip will take you to the best attractions Rome has to offer. Cherish the 1 night you have left in Rome by discovering the best things there are to see and do in the city.

Make Villa Borghese your first stop of the day. Previous visitors have rated this urban zone of rome an average of 4.6 out of 5 stars in 69,749 reviews.

Next up, make a stop at piazza del Popolo. With an average rating of 4.6 out of 5 stars by 89,807 visitors, it's easy to understand why so many people visit this square every year.

Castel Sant'Angelo is another attraction you can visit on this day of your vacation. This museum has an average rating of 4.7 out of 5 stars by 72,431 visitors. Up to 918,591 travelers come to Rome every year to see Castel Sant'Angelo with their own eyes.

When you’re finished at Castel Sant'Angelo, the perfect next stop is Altare della Patria. This architectural structure is rated an average of 4.8 out of 5 stars in 49,843 reviews. Altare della Patria attracts approximately 1,683,070 visitors annually.

If you’re keen to explore even more, then consider a visit to Circus Maximus. This circus is a top place to visit, with a rating of 4.4 out of 5 stars from 44,741 reviews.

Don’t forget to check out all the popular tours and activities you can add to your travel plan. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

As dinnertime approaches, it's time to head out for a bite to eat in Rome. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Savor the flavors at Ristorante Tema, a top pick for dinner tonight. Alternatively, Maccheroni beckons with its unique menu offerings. Also, consider RoYaL Art Cafè Roma. With its consistent customer satisfaction, it’s an excellent option for dining in Rome tonight.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in in Italy.

Embark on another extraordinary experience on day 8 of your road trip in Italy. Today, you will make 1 stop and experience some of the highlights of Rome. At the end of the day, you will enjoy the comforts of a top-rated hotel in Florence, which will be your home away from home for 1 night.

Kick off the day at largo di Torre Argentina, a top pick for today’s sightseeing. This square is rated an average of 4.5 out of 5 stars in 30,433 reviews.

Today is also your chance to visit Campo de' Fiori. Campo de' Fiori is a square with an average rating of 4.4 out of 5 stars from 51,133 reviews.

Piazza Navona is another top attraction we highly recommend you visit today. This square is rated an average of 4.7 out of 5 stars by 158,771 visitors.

Beyond the attractions mentioned above, you also have the opportunity to visit Pantheon. This roman temple is rated an average of 4.8 out of 5 stars by 189,682 visitors. Visiting Pantheon means you'll be one of 30,000,000 people who do so every year.

Lastly, don’t miss out on Trevi Fountain, a famous sculpture in Rome. This attraction is rated an average of 4.8 out of 5 stars by 343,494 travelers.

After soaking up all the sights of today's itinerary, you'll be ready to hit the road in the direction of Florence. Florence offers plenty of top-rated hotels and other places to stay on any travel budget. Check in at the hotel of your choice and take some time to relax before you head out to explore.

After a day of adventure, treat yourself to an exquisite dinner at one of Florence's best restaurants.

Treat yourself to a delightful dinner at Tijuana, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Djària - American Bar? It's another excellent option with a diverse menu. Consider reserving a table at Ristorante Buca Niccolini as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Florence.

Say good night to Florence and look forward to another great day of your road trip in Italy!

Day 9 of your road trip in Italy is your departure day. This is your chance to catch a last glimpse of Florence before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

Maximize your last day in Italy and go on a shopping spree in Florence’s shopping center. This bustling commercial district is conveniently located near your lodging, granting you leisure time to roam and explore its assortment of establishments.

If you love the adrenaline rush of hunting for the best offers and deals in Italy, you’re in for a treat. A variety of goods and gifts await your discovery. Bring a bit of Italy home with you through these charming souvenirs.

Your sightseeing of the day begins at piazzale Michelangelo, a remarkable square where it’s easy to get lost in exploration. This top attraction is rated an average of 4.8 out of 5 stars in 77,744 reviews.

Before you conclude your road trip in Italy, drop by another restaurant for a last chance at a memorable dining experience in Florence.

Esteemed as a restaurant, it features an exceptional menu. If you're in the mood for something new, try Ristorante Le Volte Firenze, another premier location with a delectable menu.

You’ll then say farewell to Florence. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Italy!