10-Day Italy Self-Drive Road Trip With Itinerary from Ancona to Florence, Siena, and Rome

Day 2 of your road trip across Italy promises a magnificent time exploring Ancona. You have 1 night left in Ancona. Take the opportunity to experience more of the best attractions and activities in the city.

Today’s agenda in Ancona includes a monument and a museum. Arch Of Trajan is must-visit monument and a great starting point for the day. Next, continue your journey to Porta Pia, a curiosity-inducing monument, located just a leisurely stroll away. Next, head to Lazzaretto Of Ancona, a heritage-rich museum, also available for your discovery today.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Ancona. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Have a fantastic dining experience at Amarcord, a highly recommended choice for tonight's dinner. If you're looking to mix things up, Bontà delle Marche offers an enticing alternative with its varied menu. Additionally, Ristorante Pizzeria Da Romano is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Ancona.

Unwind after your meal by stepping into Alla Tazza D'oro. This venue is celebrated for its extensive drink selections and cozy vibes.

Say good night to Ancona and look forward to another great day of your road trip in Italy!

On day 3 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 1 destination, Florence. When you’re not sightseeing, take time to relax at your selected hotel in Florence, where you’ll be staying for 2 nights.

Ancona is brimming with adventures. Today’s wonderful stops include a church, an art gallery, a historical landmark, a palace, a public square and much more! Begin your sightseeing adventure at the popular Basilica Of Santa Croce In Florence and allow yourself time to explore. Just a short distance away you'll find your next stop, Uffizi Gallery, a picture-perfect art gallery that draws visitors from far and near.

Continue your journey to Ponte Vecchio, one of the city’s most timeless spots that you shouldn’t miss. Another great site to visit is the well-known Palazzo Vecchio. When you're finished at the palace, Piazza Della Signoria awaits your visit. This public square is a visually striking highlight on today's itinerary.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Florence. Florence offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Florence. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Enjoy a delicious meal at Ristorante Oliviero 1962, a top-rated dining destination in Florence. If you're in the mood to try something new, consider Di Poneta Novoli, another top spot with a mouthwatering menu. You might also want to secure a reservation at Caffe San Firenze. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Florence this evening.

Cap off your dinner by heading to Manifattura, ideal for a leisurely evening with a drink in hand. Se·sto On Arno Rooftop Bar is another bar that offers an enjoyable setting. Similarly, Il Vinile is also a popular place to go on a night out, perfect for relaxing and socializing.

Savor another day of unforgettable experiences in Italy!

On day 4 of your road trip, you will have an entire day to explore Florence. You’ll stay in Florence for 1 night and discover all the best things to see and do in the area.

Oltrarno is a neighborhood that stands out as one of the must-see places in Florence. Take a moment to explore its distinct atmosphere, and don’t miss the popular sightseeing spots just a short walk away.

Start your day at David. Then, wander over to Galleria Dell'accademia. If standout sites excite you, this art gallery will be right up your alley. Nearby, you’ll also find Cathedral Of Santa Maria Del Fiore. This UNESCO world heritage-listed church is a favorite among visitors.

Florence offers plenty to explore, ensuring every moment of your visit is filled with excitement and discovery. If you're up for more, Pitti Palace is a locally renowned spot in the city that will captivate you with its unique charm. When you’re done at the palace, don’t forget to check out the romantic Piazzale Michelangelo. Take a moment to appreciate the fascinating details of this famous observation deck.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Florence. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Treat yourself to a wonderful meal at Ditta Artigianale, a top-rated dining spot in Florence. If you're in the mood for something new, try Trattoria Da Burde, another premier location with a delectable menu. You might also want to book a table at Casa Toscana. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Florence.

Explore the vibrant nightlife at Bar 50 Rosso after your meal, a hub for lively evenings and memorable moments. Or, head to Bitter Bar for a great selection of flavorful drinks and a charming setting. Furthermore, Archea Brewery is perfect for those looking to extend their night with a touch of local flavor.

Take some time to reflect on your day and savor another beautiful night in Italy.

On day 5 of your road trip in Italy, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Pisa, Lucca, and Siena. In the evening, you’ll end up in Siena, where you will stay for 2 nights.

Get ready to discover some of the most iconic wonders in Florence, including a monument, a public square, and a church. Start your day at Porta Nuova. This symbolic monument is an often recommended place to see in Florence. Then, wander over to Piazza Del Duomo, Pisa. If breathtaking sites excite you, this public square will be right up your alley. Nearby, you’ll also find Leaning Tower Of Pisa. This UNESCO world heritage-designated monument is a favorite among visitors.

Florence offers plenty to explore, ensuring every moment of your visit is filled with excitement and discovery. If you're up for more, Piazza Dell'anfiteatro is a notable spot in the city that will captivate you with its unique charm. When you’re done at the public square, don’t forget to check out the picture-perfect Basilica Of San Domenico. Take a moment to appreciate the fascinating details of this intriguing church.

At the end of the day, you will drive to Siena, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

After a day of adventure, treat yourself to an exquisite dinner at one of Siena's best restaurants.

Enjoy a lovely meal at Enoteca I Terzi, a top-rated place to have dinner tonight. Alternatively, if your taste buds call for something different, Ristorante Tar-Tufo is another top choice with a popular menu. You could also check for a table at Antica Trattoria Papei. As an establishment that gains consistently high praises from customers, it’s an ideal choice in Siena tonight.

Keep the excitement of the evening going by visiting a bar or two. Meet Life Cafè is an excellent place to start. You could also check out Maudit Pub, offering a different kind of charm. A last recommendation for the day is Bar Impero Siena. This bar promises an enjoyable experience with tasty drinks and a vibrant setting.

Raise your glass to another unforgettable day in Italy!

Day 6 of your road trip will take you to the best attractions Siena has to offer. Cherish the 1 night you have left in Siena by discovering the best things there are to see and do in the city.

Siena is home to plenty of attractions that offer family-friendly attractions, romantic experiences, and breathtaking views! Start at Siena Cathedral, a well-known church that is worthwhile a visit in the city. Nearby, you’ll find Piazza Del Campo, enchanting visitors with its visually striking appeal. Continue your exploration at Tower Of Mangia. This monument is one of the city’s most locally appreciated spots.

Enjoy the freedom of exploring Siena at your own pace and find hidden gems along the way. If you want to see more picture-perfect spots, make sure to visit Pubblico Palace.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

As you explore more of Siena, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Enjoy a delicious meal at Osteria Quattro Venti, a top-rated dining destination in Siena. If you're in the mood to try something new, consider Fischi per Fiaschi, another top spot with a mouthwatering menu. You might also want to secure a reservation at Osteria da Divo. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Siena this evening.

After savoring a delicious meal, step into the vibrant nightlife at Charlie Mixology Bar Di Aldinucci Riccardo, where the evening is just getting started. In the same way, Bar Pinacoteca offers a unique charm perfect for experiencing the local bar scene in Siena. San Paolo Pub is another top-recommended bar that is sure to get you into the mood for some dancing and celebrating.

Savor another day of unforgettable experiences in Italy!

Dive into day 7 of your remarkable road trip in Italy. Today you will explore Rome, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Rome. You’ll stay here for 2 nights.

Whether you prefer a leisurely exploration or a more fast-paced adventure, this itinerary in Siena allows for both. Start by heading to Colosseum. This timeless archeological site provides an insightful glimpse into the city's identity. Next, discover Roman Forum, a culturally significant archeological site, promising a delightful encounter.

Continue your sightseeing with a visit to Trevi Fountain, a wondrous monument. When you’re done, don’t forget to make a stop at the wondrous Pantheon. Round off your day at Piazza Navona, another gem in Siena with enchanting features to discover.

When you’re done exploring for the day, you’ll drive to your hotel in Rome. Check in and spend some time relaxing before you head out to tour the city.

As dinnertime approaches, it's time to head out for a bite to eat in Rome. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Dine in style at La Bottega Roma, a top recommendation for dinner tonight. Or, for a change of pace, Pasta In Corso boasts a menu that's sure to impress. Also, be sure to check out Trattoria Vecchia Roma. Known as a local hotspot, it’s a great choice for tonight in Rome.

Continue your evening by exploring the vibrant nightlife scene at La Botticella Of Poggi Giovanni, a prime destination for a thrilling night out. Also, don’t forget to check out Almalu Trastevere, a bar that offers unique local touches. Likewise, Bar Viminale Di Pepi Maurilio provides an excellent alternative for a fun evening.

Raise your glass and celebrate another amazing day of your road trip in Italy!

On day 8 of your road trip, you’ll start and end your day in Rome, where you'll stay for 1 night more.

Enjoy the perfect balance of relaxation and exploration in Rome today. One of the most iconic attractions included on the itinerary is Vatican Museums.

Throughout the day, make sure to take breaks to appreciate the surroundings. Next up, visit the iconic St. Peter's Basilica. After exploring the major basilica, head to Castel Sant'angelo. This impressive castle is a highlight in Rome. As your day continues, stop by Piazza Di Spagna, known for its romantic features. Lastly, don’t forget to check out the astonishing Spanish Steps. Enjoy exploring this incredible public square at your own pace.

When you’re done exploring for the day, you’ll return to Rome and your accommodation.

After a day of adventure, treat yourself to an exquisite dinner at one of Rome's best restaurants.

Don’t miss out on dining at RomAntica, a top-rated dining destination in Rome. If you're in the mood to try something new, consider Coso Ristorante, another top spot with a mouthwatering menu. You might also want to secure a reservation at DEROMA - Farine Romane. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Rome this evening.

After enjoying a delightful dinner, why not delve into the vibrant local bar scene? You might want to spend the evening at Sant' Eustachio Caffè, a well-loved spot among locals and tourists. Or, head to Yellowsquare Rome. This bar boasts a welcoming environment that is perfect for winding down. You could also continue your night at Caffè Portofino, another top-rated place in the area.

Relax and reminisce about your day in Italy and look forward to more memorable moments to come!

Experience an unparalleled adventure on day 9 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 2 vibrant destinations - Santa Maria degli Angeli and Perugia. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Ancona. You will spend 1 night here for some well-deserved relaxation.

Today’s route brings family-friendly attractions, breathtaking views, and picturesque spots. The first attraction of today is Basilica Of San Francesco D'assisi. This interesting church is an UNESCO world heritage-listed place to see in Rome. Continue your discovery at National Archaeological Museum Of Umbria, an eye-catching museum with stories to tell.

As you stroll around Rome, take in the distinct atmosphere and learn what makes this town so unique. Maximize your sightseeing with a visit to The Fontana Maggiore. This intriguing monument offers a historic encounter with Rome. Next, make your way to Piazza Iv Novembre to add another highlight to your day. After that, visit Perugia Cathedral, a worthwhile church that’s sure to impress. Whether you decide to get entrance tickets for all attractions or you prefer admiring from a distance, amazing experiences await on this day in Rome.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Ancona. Ancona offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

Indulge in a memorable dining experience at one of Ancona's most popular restaurants, and connect with friendly locals for an authentic adventure.

Don’t miss out on dining at Pizzeria Pulcinella, a top-rated dining destination in Ancona. If you're in the mood to try something new, consider Donegal Irish Pub, another top spot with a mouthwatering menu. You might also want to secure a reservation at Vino E Cucina Miscia. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Ancona this evening.

Head back to your accommodation in Ancona and get some rest in preparation for another magical day of your road trip in Italy!