13-Day Italy Self-Drive Road Trip With Itinerary from Florence traveling south to Pisa, Viterbo, Naples, Rome, and Perugia

On day 2 of your road trip, you will have an entire day to explore Florence. You’ll stay in Florence for 1 night and discover all the best things to see and do in the area.

Discover a day packed with a charming, a mesmerizing, an instagrammable, a historic, a grand, and a detailed in Florence. Begin your sightseeing with Piazza Della Signoria. This impressive public square is one of the top attractions in the city. Proceed to Uffizi Gallery, another must-visit attraction that enhances the city’s allure.

As you wander through the inviting streets of Florence, soak in the lively ambiance and take the opportunity to snap some photos. Next, head to Ponte Vecchio. This globally renowned historical landmark is a traveler-favorite. Not far away, you’ll find Pitti Palace, another key site on your sightseeing itinerary. Conclude your day at The Boboli Gardens and uncover why it's recognized as one of the city's most interesting attractions.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Florence. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Start your culinary exploration in Florence by securing a reservation at Enoteca Pinchiorri. This renowned restaurant holds 3 Michelin star and offers an exceptional menu of italian contemporary cuisine. For another dining delight, visit Santa Elisabetta, celebrated for its delectable creative and mediterranean menu. This acclaimed 2-star Michelin-recipient consistently leaves guests satisfied, making it a must-visit during your holiday. Looking for a different experience? Discover Gucci Osteria da Massimo Bottura, a top local spot known for its tantalizing italian contemporary and international menu. With a 1-star Michelin recognition, it guarantees an exceptional dining adventure.

Explore the vibrant nightlife at Bar 50 Rosso after your meal, a hub for lively evenings and memorable moments. Or, head to Bitter Bar for a great selection of flavorful drinks and a charming setting. Furthermore, Archea Brewery is perfect for those looking to extend their night with a touch of local flavor.

Say good night to Florence and look forward to another great day of your road trip in Italy!

On day 3 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 1 destination, Florence. When you’re not sightseeing, take time to relax at your selected hotel in Pisa, where you’ll be staying for 1 night.

Today's adventure in Florence promises more breathtaking discoveries and enriching experiences! Begin at Basilica Of Santa Croce In Florence. This culturally significant church is a highlight of any visit in the city. Then, enjoy Galleria Dell'accademia, another photogenic attraction that never fails to captivate visitors. Next, head over to Cathedral Of Santa Maria Del Fiore, one of the city’s most impressive attractions, known for its majestic features.

If you’re looking for more, spend time soaking in the atmosphere of Basilica Di Santa Maria Novella, Firenze (fi). This visually striking church is frequented by locals and tourists alike. To complete your memorable day, make sure to take a stroll around the area.

After soaking up all the sights of today's itinerary, you'll be ready to hit the road in the direction of your accommodation in Pisa. Pisa offers plenty of top-rated hotels and other places to stay on any travel budget. Take some time to relax before you head out to explore.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Pisa. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Make sure to reserve a table at Anima di Grano Pizzeria Napoletana Pisa Italy, an iconic dining spot in Pisa. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of il Mercante, a popular restaurant in Pisa. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of La Ghiotteria, a hidden gem nestled in Pisa. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Extend your evening after a delightful meal by visiting Jeffer Cocktails & Friends, which offers the perfect atmosphere for a night out. Moreover, Le Parisien Wine Bar is another popular option for a drink or two. Likewise, Las Volta Cocktailbar also provides a great ambiance for reminiscing about the day and raising a toast to your vacation.

As the sun sets on another day of adventure, rest up and recharge for the next leg of your road trip in Italy.

Dive into day 4 of your remarkable road trip in Italy. Today you will explore Pisa, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Viterbo. You’ll stay here for 1 night.

Get ready to discover some of the most iconic wonders in Pisa, including a public square, a monument, and a church. Start your day at Knights' Square. This culturally significant public square is an increasingly popular place to see in Pisa. Then, wander over to Leaning Tower Of Pisa. If UNESCO world heritage-designated sites excite you, this monument will be right up your alley. Nearby, you’ll also find Piazza Del Duomo, Pisa. This UNESCO world heritage-designated public square is a favorite among visitors.

Pisa offers plenty to explore, ensuring every moment of your visit is filled with excitement and discovery. If you're up for more, Pisa Cathedral is a worthwhile spot in the city that will captivate you with its unique charm.

At the end of the day, you will drive to Viterbo, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As you explore more of Viterbo, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Celebrate another amazing day of your road trip adventure in Italy!

Experience an unparalleled adventure on day 5 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 2 vibrant destinations - Caserta and San Leucio-complex. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Naples. You will spend 2 nights here for some well-deserved relaxation.

Fasten your seatbelt and make your way to your next stop. Caserta, home to many well-known sights in the region, is a lovely destination on today’s itinerary. Keep in mind that your travel time from Viterbo to Caserta may take around 2 hours 43 min without traffic disruptions. Upon arrival in Caserta, we highly recommend checking out some of the top attractions.

Your self-guided tour starts at Fountain Of Aeolus, an up-and-coming park that is sure to impress. Take in the surroundings and enjoy the freedom of exploring before you continue your journey. Next, head to Giardini Reali - Parco Reggia Di Caserta and admire its UNESCO world heritage-designated features. When you’re ready, continue to Palace Of Caserta, a well-known palace beloved by locals and tourists alike.

San Leucio-complex’s wonders await as you prepare for another journey on the road, leaving the breathtaking surroundings of Caserta behind. This drive usually takes around 13 min. San Leucio-complex welcomes you with a multitude of unique vacation experiences.

Spend your afternoon discovering Complesso Monumentale Belvedere San Leucio, an underrated museum known for its awe-inspiring features.

When you’re done exploring for the day, you’ll drive to your hotel in Naples. Check in and spend some time relaxing before you head out to tour the city.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Naples. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Experience a harmony of flavors at Veritas in Naples by securing a reservation in advance. Known for its 1-star Michelin status, Veritas offers a delightful variety of dishes highlighting its delicious campanian and contemporary menu. If you're seeking an alternative culinary experience, be sure to explore Il Comandante, a highly recommended restaurant known for its enticing creative and mediterranean cuisine. This popular 1-star Michelin-awarded venue consistently exceeds expectations, ensuring a memorable holiday experience. Ready for another culinary adventure? Indulge your senses at ARIA, a highly acclaimed restaurant celebrated for its exceptional contemporary and modern menu.

After enjoying a delightful dinner, why not delve into the vibrant local bar scene? You might want to spend the evening at Happening Cocktail Bar, a well-loved spot among locals and tourists. Or, head to Shanti Art Musik Bar. This bar boasts a welcoming environment that is perfect for winding down. You could also continue your night at Gran Caffè Gambrinus, another top-rated place in the area.

Raise your glass and celebrate another amazing day of your road trip in Italy!

On day 6 of your road trip in Italy, you’ll start and end your day in Naples, but spend the day exploring what’s beyond the city. Since you will return to Naples for 1 night more, there’s no need to rush. Experience Ravello, Castiglione, Amalfi, Pompei, and Naples to the fullest today with this curated day itinerary!

Today’s route brings a charming, a gorgeous, an instagrammable, a respected, and a grand. The first attraction of today is Piazza Del Plebiscito. This impressive public square is a respected place to see in Naples.

Once you're ready to continue your road trip, it's time to buckle up and drive, eagerly anticipating your arrival in Ravello. This drive usually takes around 1 hour 10 min, without any stops or traffic disruptions.

Your self-guided tour starts at Villa Rufolo, a notable historical landmark that is sure to impress. Take in the surroundings and enjoy the freedom of exploring before you continue your journey.

After soaking in Ravello’s unique atmosphere, jump into the car with a full heart and drive in the direction of your next destination: Castiglione. Expect your car journey to take a minimum of 10 min. When you arrive in Castiglione, it's time to take a break from the road.

Spend your afternoon discovering Villa Cimbrone Gardens, an up-and-coming botanical garden known for its romantic features.

As you’ve unraveled the marvels of Castiglione, it’s time to gear up for the next part of your road trip adventure. Under favorable conditions, your drive to Amalfi may take around 12 min. Upon your arrival in Amalfi, you’ll be greeted with the opportunity to do some sightseeing and exploring.

Savor the rest of your day by heading to Amalfi Coast, a widely recognized coast that draws visitors from near and far.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Naples.

After a day of adventure, treat yourself to an exquisite dinner at one of Naples's best restaurants.

Dine in style at Antica Pizzeria Di Matteo, a top recommendation for dinner tonight. Or, for a change of pace, Mercure Napoli Centro Angioino boasts a menu that's sure to impress. Also, be sure to check out La Lazzara Trattoria e Pizzeria. Known as a local hotspot, it’s a great choice for tonight in Naples.

Explore the vibrant nightlife at Archivio Storico - Cocktail Bar & Wonderfood after your meal, a hub for lively evenings and memorable moments. Or, head to Archeobar for a great selection of flavorful drinks and a charming setting. Furthermore, Babette Pub is perfect for those looking to extend their night with a touch of local flavor.

Take some time to reflect on your day and savor another beautiful night in Italy.

Embark on another extraordinary experience on day 7 of your road trip in Italy. Today, you will make 1 stop and experience some of the highlights of Naples. At the end of the day, you will enjoy the comforts of a top-rated hotel in Rome, which will be your home away from home for 4 nights.

Today’s well-planned self-sightseeing route offers several a charming, a mesmerizing, a photogenic, a heritage-rich, a symbolic, and a noteworthy. Whether you decide to explore Naples on foot, use public transport, or join a guided tour, there are a few attractions you don’t want to miss. Ovo Castle is the first of them. Spend some time admiring this enchanting castle before continuing your journey. Naples National Archaeological Museum is your next stop. This interesting museum is one of the best-rated sights in Naples.

Consider grabbing some lunch or a light snack to keep your energy going. Beyond the above-mentioned attractions, today is also the perfect time to visit Cappella Sansevero. This photogenic museum is a sight to behold.

After soaking up all the sights of today's itinerary, you'll be ready to hit the road in the direction of your accommodation in Rome. Rome offers plenty of top-rated hotels and other places to stay on any travel budget. Take some time to relax before you head out to explore.

As dinnertime approaches, it's time to head out for a bite to eat in Rome. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Dive into a culinary adventure like no other in Rome by booking a table at La Pergola. This popular restaurant holds 3 Michelin star and offers an exceptional menu of mediterranean and contemporary cuisine. For another culinary dining option, venture to Il Pagliaccio, celebrated for its delectable creative and innovative menu. This acclaimed 2-star Michelin-recipient consistently leaves guests satisfied, ensuring an essential addition to your holiday itinerary. Seeking an alternative? Discover Enoteca La Torre, a top local restaurant known for its tantalizing mediterranean and creative menu. With a 2-star Michelin recognition, it promises an exceptional dining experience not to be missed.

After your meal, keep the night alive at a bar like La Botticella Of Poggi Giovanni, known for its lively atmosphere. Almalu Trastevere is another top recommendation that provides the perfect setting with well-crafted drinks and a welcoming ambiance. Similarly, Bar Viminale Di Pepi Maurilio offers an excellent atmosphere for those looking to amp up the evening.

Say good night to Rome and look forward to another great day of your road trip in Italy!

Day 8 offers a multitude of experiences. You will stay in Rome for 3 nights more, offering you enough time to explore at a relaxed pace.

Start by visiting Spanish Steps, a prime spot to begin your journey. This enchanting public square is sure to impress. Next on your list is Piazza Di Spagna, another must-visit landmark and iconic public square renowned for its symbolic features.

While exploring and sightseeing, take time to savor the ambiance of Rome by sampling some local delicacies or having a drink. When you’re ready for more sightseeing, head to Trevi Fountain. This enchanting monument is a remarkable attraction that offers a unique experience. Roman Forum also adds charm to your journey, and Colosseum wraps up your day with its picture-perfect appeal.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

As dinnertime approaches, it's time to head out for a bite to eat in Rome. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Savor the flavors at RomAntica, a top pick for dinner tonight. Alternatively, Coso Ristorante beckons with its unique menu offerings. Also, consider DEROMA - Farine Romane. With its consistent customer satisfaction, it’s an excellent option for dining in Rome tonight.

Keep the evening going at Sant' Eustachio Caffè, a great choice for enjoying the after-dinner hours with a drink. You could also go to Yellowsquare Rome, which offers a similarly pleasant setting and great drinks. Another option is Caffè Portofino, which provides an inviting environment for unwinding after a busy day out.

Relax and reminisce about your day in Italy and look forward to more memorable moments to come!

Day 9 of your road trip across Italy promises a magnificent time exploring Rome. You have 2 nights left in Rome. Take the opportunity to experience more of the best attractions and activities in the city.

Set out on a day brimming with a photogenic, a history-steeped, a sacred, a symbolic, a charming, an awe-inspiring, and a detailed. Start at the well-known Largo Di Torre Argentina, a photogenic archeological site in Rome. Next, go to Pantheon.

After visiting Largo Di Torre Argentina and Pantheon, take time to explore Rome's streets and absorb its charm. Continue your sightseeing by heading to Piazza Navona. This history-steeped public square offers a unique experience. Campo De' Fiori is another noteworthy stop. End your self-guided sightseeing tour on top with a visit to Castel Sant'angelo, one of the most history-steeped places to visit in Rome.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

After a day of adventure, treat yourself to an exquisite dinner at one of Rome's best restaurants.

Treat yourself to a delicious dinner at Hotel de Russie, an excellent option for tonight's dining. Looking for something different? La Taverna Italiana offers a tantalizing alternative with its diverse menu. And don’t miss The Parrot Bar. With its reputation for pleasing customers, it’s a fantastic choice for tonight in Rome.

Cap off your dinner by heading to The Apartment Bar Roma, ideal for a leisurely evening with a drink in hand. Hotel Hassler Roma is another bar that offers an enjoyable setting.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in in Italy.

Day 10 of your road trip will take you to the best attractions Rome has to offer. Cherish the 1 night you have left in Rome by discovering the best things there are to see and do in the city.

Get ready to discover some of the most iconic wonders in Rome, including a public square, a park, a church, an archeological site, a monument and much more! Start your day at Piazza Del Popolo. This romantic public square is a famous place to see in Rome. Then, wander over to Villa Borghese. If serene sites excite you, this park will be right up your alley. Nearby, you’ll also find Basilica Di Santa Maria Maggiore. This culturally significant church is a favorite among visitors.

Rome offers plenty to explore, ensuring every moment of your visit is filled with excitement and discovery. If you're up for more, Circus Maximus is a well-known spot in the city that will captivate you with its unique charm. When you’re done at the archeological site, don’t forget to check out the masterful Altare Della Patria. Take a moment to appreciate the fascinating details of this captivating monument in Rome.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

As you explore more of Rome, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Have a fantastic dining experience at Sofitel Roma Villa Borghese, a highly recommended choice for tonight's dinner. If you're looking to mix things up, Centro offers an enticing alternative with its varied menu. Additionally, Ristorante Tema is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Rome.

As the sun sets on another day of adventure, rest up and recharge for the next leg of your road trip in Italy.

On day 11 of your road trip in Italy, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Vatican City. In the evening, you’ll end up in Perugia, where you will stay for 1 night.

Whether you prefer a leisurely exploration or a more fast-paced adventure, this itinerary in Vatican City allows for both.

When you’re ready to jump back into the car and say goodbye to Rome, you’ll hit the road in the direction of Vatican City, Vatican City. Witness the landscapes transform as you cross the border to Vatican City. This drive usually takes around 11 min. When you arrive, enjoy some sightseeing.

After taking in the atmosphere, continue to Sistine Chapel, a spectacular chapel that is a must-see for anyone visiting the region. Make sure to also explore Vatican Museums, an iconic art museum that offers a unique experience.

At the end of the day, you will drive to Perugia, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

After a day of adventure, treat yourself to an exquisite dinner at one of Perugia's best restaurants.

Treat yourself to a delightful dinner at Ristorante Settimo Sigillo, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Caffè Baglioni? It's another excellent option with a diverse menu. Consider reserving a table at Bar Pellas as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Perugia.

Cap off your dinner by heading to Tommi Bar, ideal for a leisurely evening with a drink in hand. Valentina is another bar that offers an enjoyable setting. Similarly, Caffe Dal Perugino is also a popular place to go on a night out, perfect for relaxing and socializing.

Raise your glass to another unforgettable day in Italy!

On day 12 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 2 destinations, Santa Maria degli Angeli and Siena. When you’re not sightseeing, take time to relax at your selected hotel in Florence, where you’ll be staying for 1 night.

Continue your road trip and head to your next destination, Santa Maria degli Angeli. This car ride takes around 32 min.

Basilica Of San Francesco D'assisi is a captivating church we recommend making time to visit today. Discover its grand features before continuing your self-guided tour.

Set your GPS to Siena and hit the road. Expect a journey of approximately 1 hour 38 min without stops. Soak in the beautiful landscapes as you drive and look forward to exploring your next destination. Siena beckons with new experiences!

Head to Piazza Del Campo, a widely recognized public square in Siena. Explore its enchanting features at your own pace before you continue your journey to your next sight, Siena Cathedral. This notable church is a top recommendation in the area. When you’re ready to explore more, Fortezza Medicea (siena) is an excellent choice. Spend some time discovering what some claim to be the most standout monument in the region.

When you’re done exploring for the day, you’ll drive to your hotel in Florence. Check in and spend some time relaxing before you head out to tour the city.

Indulge in a memorable dining experience at one of Florence's most popular restaurants, and connect with friendly locals for an authentic adventure.

Make sure to book a table at Ristorante Buca Mario, a popular restaurant in Florence. This acclaimed restaurant and its mouthwatering dishes have earned the admiration of countless food lovers. Alternatively, experience a taste of Florence at Agricola Toscana, a popular local restaurant. With a menu designed to impress, it promises a journey of flavors that will leave you captivated. Another top-rated restaurant to try is Eataly Firenze. As a dining spot that gains high praise from guests, it’s an ideal choice to enhance your time to Florence tonight.

Cap off your culinary experience with a visit to some of the most celebrated bars in the area. For instance, Gosh* stands out as an excellent choice for a post-dinner cocktail. Alternatively, Antico Caffè Del Moro - Art Bar Firenze offers an ideal atmosphere to enjoy the pleasures of the night. Quelo Bar is also a great option that provides a perfect setting for a relaxing evening.

Savor another day of unforgettable experiences in Italy!