7-Day Italy Self-Drive Road Trip With Itinerary from Pescara to Rome and Florence

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Description

Explore the best of Italy on a 7-day road trip! Uncover hidden gems and experience the rich culture firsthand as you journey through Pescara, Rome, Florence, Pisa, and Santa Maria degli Angeli. This road trip itinerary in Italy seamlessly combines exploration with relaxation.

This perfectly planned road trip itinerary in Italy takes you through some of the best places to see in the country. You will spend 2 nights in Pescara, 2 nights in Rome, and 2 nights in Florence. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Italy. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have got you covered.

Upon arriving in Pescara, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Italy on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Italy. Trevi Fountain and Colosseum are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Pantheon, learn more about the unique Piazza Navona, and immerse yourself in the vibrant atmosphere of St. Peter's Basilica.

As you hit the open road and drive through Pescara, Rome, Florence, Pisa, and Santa Maria degli Angeli, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Italy. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Italy.

Throughout your road trip in Italy, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Italy.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodation, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Italy fill up quickly, so book your spot early. Select a date and start planning your road trip in Italy today!

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Itinerary summary

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Days
Destination
Attractions
Overnight
Day
City & Overnight
Attractions
Parco Giochi Paperopoli
ColosseumRoman ForumTrevi FountainPantheonPiazza Navonapiazza del Popolo
Vatican MuseumsSistine ChapelSt Peter's BasilicaPiazza di SpagnaSpanish StepsTrastevereVia dei Condotti
Basilica of Santa Croce in FlorenceFountain of NeptuneUffizi GalleryPonte Vecchiopiazza della Signoria
Leaning Tower of PisaPiazza del Duomo, PisaPisa CathedralCentral MarketCathedral of Santa Maria del Fiorepiazzale Michelangelo
Basilica of San Francesco d'AssisiPiazza del ComuneBasilica di Santa ChiaraRocca Maggiore
Ponte del Mare

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Day 1

Day 1

  • Pescara - Arrival day
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  • Parco Giochi Paperopoli
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Say hello to Pescara! Your exciting road trip through Italy is just about to start. Navigating the top places to see in the region is a breeze with a car. The rental vehicle of your choice will be ready for pickup upon your arrival in the city. You will stay in Pescara for 1 night before you continue your adventure!

Pescara is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Parco Giochi Paperopoli, or just taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

Find your way to your hotel in Pescara. We recommend choosing a hotel in a central location for easy exploring. Check-in typically starts between 2 and 4 PM at hotels in Italy. Settle in and make plans for the evening.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Pescara, it's often a good idea to reserve a table in advance.

Enjoy a delicious meal at Taverna 58, a highly-rated dining destination in Pescara. If you're eager to try something different, consider Ristorante Carlo Ferraioli, another top spot with a tantalizing menu. You might also want to secure a reservation at Sesamo Nero. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Pescara this evening.

After your meal, keep the night alive at a bar like Posa Caffè Pescara, known for its lively atmosphere. Bar Mixer is another top recommendation that provides the perfect setting with well-crafted drinks and a welcoming ambiance. Similarly, Temple Bar Irish Pub offers an excellent atmosphere for those looking to amp up the evening.

Raise a toast to the start of your 7-day road trip in Italy!

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Day 2

Day 2

  • Pescara
  • Rome
  • More

Drive 220 km, 3 hours 35 min

  • Colosseum
  • Roman Forum
  • Trevi Fountain
  • Pantheon
  • Piazza Navona
  • piazza del Popolo
  • More

On day 2 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 1 destination, Rome. When you’re not sightseeing, take time to relax at your selected hotel in Rome, where you’ll be staying for 2 nights.

Today’s well-planned self-sightseeing route offers several family-friendly attractions, breathtaking views, and photo-friendly spots. Whether you decide to explore Pescara on foot, use public transport, or join a guided tour, there are a few attractions you don’t want to miss. Colosseum is the first of them. Spend some time admiring this historic archeological site before continuing your journey. Roman Forum is your next stop. This timeless archeological site is one of the best-rated sights in Pescara.

Consider grabbing some lunch or a light snack to keep your energy going. Beyond the above-mentioned attractions, today is also the perfect time to visit Trevi Fountain. This visually striking monument is a sight to behold. To round off your sightseeing experience, visit Pantheon and Piazza Navona.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Rome. Rome offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

As you explore more of Rome, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Treat yourself to a delightful dinner at La Bottega Roma, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Pasta In Corso? It's another excellent option with a diverse menu. Consider reserving a table at Trattoria Vecchia Roma as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Rome.

Following your dinner, dive into the local bar culture at La Botticella Of Poggi Giovanni. Enjoy this evening's relaxed ambiance with delightful drinks. Alternatively, go to Almalu Trastevere, the perfect place for those looking to experience the best of the nightlife. Similarly, Bar Viminale Di Pepi Maurilio provides excellent drinks and a great atmosphere, ensuring a memorable night out.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in in Italy.

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Day 3

Day 3

  • Rome
  • More

Drive 16 km, 1 hour 4 min

  • Vatican Museums
  • Sistine Chapel
  • St Peter's Basilica
  • Piazza di Spagna
  • Spanish Steps
  • Trastevere
  • Via dei Condotti
  • More

On day 3 of your road trip, you’ll start and end your day in Rome, where you'll stay for 1 night more.

Trastevere is a fantastic place you can explore today in Vatican City. This neighborhood is a testament to the city’s character, and it's easy to spend hours just walking around and admiring the surroundings. Soak in the Vatican City-way-of-life and take advantage of the nearby must-see sights located nearby.

Start your adventure at Vatican Museums. This iconic art museum is a must-visit for travelers looking for a unique holiday experience. Make your way to Sistine Chapel located in Rome for an enchanting atmosphere.

Next, immerse yourself in the setting of St. Peter's Basilica. After the major basilica, continue your tour of the city with a visit to Piazza Di Spagna. This public square has a majestic appeal. For a change of pace, head to Spanish Steps. As one of the most spectacular attractions in Rome, this public square is an excellent place to end your self-guided tour.

When you’re done exploring for the day, you’ll return to Rome and your accommodation.

As dinnertime approaches, it's time to head out for a bite to eat in Rome. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Enjoy a lovely meal at RomAntica, a top-rated place to have dinner tonight. Alternatively, if your taste buds call for something different, Coso Ristorante is another top choice with a popular menu. You could also check for a table at DEROMA - Farine Romane. As an establishment that gains consistently high praises from customers, it’s an ideal choice in Rome tonight.

Unwind after your meal by stepping into Sant' Eustachio Caffè. This venue is celebrated for its extensive drink selections and cozy vibes. Alternatively, Yellowsquare Rome offers a dynamic and energetic atmosphere for a glass or two. Don’t overlook Caffè Portofino, another top-rated bar in the area.

Say good night to Rome and look forward to another great day of your road trip in Italy!

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Day 4

Day 4

  • Rome
  • Florence
  • More

Drive 276 km, 3 hours 22 min

  • Basilica of Santa Croce in Florence
  • Fountain of Neptune
  • Uffizi Gallery
  • Ponte Vecchio
  • piazza della Signoria
  • More

Embark on another extraordinary experience on day 4 of your road trip in Italy. Today, you will make 1 stop and experience some of the highlights of Florence. At the end of the day, you will enjoy the comforts of a top-rated hotel in Florence, which will be your home away from home for 2 nights.

Today's adventure in Rome promises more breathtaking discoveries and enriching experiences! Begin at Basilica Of Santa Croce In Florence. This monumental church is a highlight of any visit in the city. Then, enjoy Fountain Of Neptune, another masterful attraction that never fails to captivate visitors. Next, head over to Uffizi Gallery, one of the city’s most astonishing attractions, known for its romantic features.

If you’re looking for more, spend time soaking in the atmosphere of Ponte Vecchio. This respected historical landmark is frequented by locals and tourists alike. To complete your memorable day, make sure to visit Piazza Della Signoria, a spectacular public square, and take a stroll around the area.

At the end of the day, you will drive to Florence, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

After a day of adventure, treat yourself to an exquisite dinner at one of Florence's best restaurants.

Have a fantastic dining experience at Ristorante Oliviero 1962, a highly recommended choice for tonight's dinner. If you're looking to mix things up, Di Poneta Novoli offers an enticing alternative with its varied menu. Additionally, Caffe San Firenze is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Florence.

Keep the evening going at Manifattura, a great choice for enjoying the after-dinner hours with a drink. You could also go to Se·sto On Arno Rooftop Bar, which offers a similarly pleasant setting and great drinks. Another option is Il Vinile, which provides an inviting environment for unwinding after a busy day out.

As the sun sets on another day of adventure, rest up and recharge for the next leg of your road trip in Italy.

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Day 5

Day 5

  • Florence
  • More

Drive 182 km, 3 hours 14 min

  • Leaning Tower of Pisa
  • Piazza del Duomo, Pisa
  • Pisa Cathedral
  • Central Market
  • Cathedral of Santa Maria del Fiore
  • piazzale Michelangelo
  • More

At the end of the day, you'll drive back to Florence, where you'll stay for 1 night more.

Discover a day packed with family-friendly attractions, scenic views, and photo-friendly spots in Florence. Begin your sightseeing with Leaning Tower Of Pisa. This world-famous monument is one of the top attractions in the city. Proceed to Piazza Del Duomo, Pisa, another must-visit attraction that enhances the city’s allure.

As you wander through the inviting streets of Florence, soak in the lively ambiance and take the opportunity to snap some photos. Next, head to Pisa Cathedral. This locally appreciated church is a traveler-favorite. Not far away, you’ll find Central Market, another key site on your sightseeing itinerary. Conclude your day at Cathedral Of Santa Maria Del Fiore and uncover why it's recognized as one of the city's most widely recognized attractions.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Florence.

As you explore more of Florence, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Treat yourself to a wonderful meal at Ditta Artigianale, a top-rated dining spot in Florence. If you're in the mood for something new, try Trattoria Da Burde, another premier location with a delectable menu. You might also want to book a table at Casa Toscana. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Florence.

Cap off your culinary experience with a visit to some of the most celebrated bars in the area. For instance, Bar 50 Rosso stands out as an excellent choice for a post-dinner cocktail. Alternatively, Bitter Bar offers an ideal atmosphere to enjoy the pleasures of the night. Archea Brewery is also a great option that provides a perfect setting for a relaxing evening.

Head back to your accommodation in Florence and get some rest in preparation for another magical day of your road trip in Italy!

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Day 6

Day 6

  • Florence
  • Pescara
  • More

Drive 403 km, 5 hours 30 min

  • Basilica of San Francesco d'Assisi
  • Piazza del Comune
  • Basilica di Santa Chiara
  • Rocca Maggiore
  • More

On day 6 of your road trip in Italy, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Santa Maria degli Angeli. In the evening, you’ll end up in Pescara, where you will stay for 1 night.

Prepare for a day full of fun adventures, breathtaking views, and picturesque spots. When you’re ready, kick off your sightseeing adventure at Basilica Of San Francesco D'assisi. This interesting church is a must-visit for anyone seeking a unique vacation experience. Another sight you shouldn’t miss is Piazza Del Comune, one of the town’s most promising highlights.

Next, check out Basilica Di Santa Chiara, one of the most curiosity-inducing places to see in Florence. This church is a favorite among locals and travelers alike. Enjoy some downtime and refreshments before continuing to your next stop, Rocca Maggiore. Wander around and soak in the symbolic atmosphere this castle offers.

When you’re done exploring for the day, you’ll drive to your hotel in Pescara. Check in and spend some time relaxing before you head out to tour the city.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Pescara. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Make sure to reserve a table at Ciacco, an iconic dining spot in Pescara. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Bar Sara, a popular restaurant in Pescara. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Ristorante Franco, a hidden gem nestled in Pescara. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

After your delicious meal, get a taste of the vibrant nightlife with a visit to Bar Napoli, known for its inviting atmosphere. Bar Supermarket is another great option if you’re looking for a place to get the night started. Similarly, Post Bar provides a great setting to enjoy the night away.

Take some time to reflect on your day and savor another beautiful night in Italy.

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Day 7

Day 7

  • Pescara - Departure day
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  • Ponte del Mare
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Day 7 of your road trip in Italy is your departure day. This is your chance to catch a last glimpse of Pescara before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, begin at Ponte Del Mare. This up-and-coming boardwalk is a popular place to see in the city.

On your last day in Italy, take time to indulge in shopping at Pescara’s popular marketplace, Centro Commerciale Pescara Porta Nuova. Look for keepsakes or souvenirs to remind you of your trip.

Before you conclude your road trip in Italy, drop by another restaurant for a last chance at a memorable dining experience in Pescara.

If you're in the mood for something new, try La Taverna Antica, another premier location with a delectable menu.

You’ll then say farewell to Pescara. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Italy!

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