Luxury 10-Day Italy Road Trip from Genoa traveling south to Florence, Rome, and Pisa

Your luxury holiday in Italy begins as soon as you reach the city of Genoa. There, you’ll pick up the luxury rental vehicle of your choice and hit the roads!

Drop by the renowned piazza De Ferrari. This popular square has been rated an average of 4.6 out of 5 stars by 34,312 visitors.

Tonight, you will be treated to a stay at one of the best luxury hotels in Genoa. We have picked out three of the most exclusive luxury lodging and hotel options for you to choose from.

After a long day of discovering the unique quirks of Italy, it’s an excellent idea to sit down for a lovely meal or enjoy a refreshing drink. We’ve gathered the most recommended dining and drinking spots in Genoa so you can check out the menus and make advance reservations.

Prepare for an extraordinary culinary adventure in Genoa by booking a table at The Cook, a 1-star Michelin restaurant that boasts an exceptional modern menu. For a different flavor experience, head to San Giorgio, renowned for its delectable modern and ligurian dishes. This 1-star Michelin restaurant consistently wows guests, making it a memorable stop during your holiday. Looking for another option? Visit Il Marin, a local gem known for its delightful seafood and contemporary cuisine in Genoa. Nestled in the city's heart, this 1-star Michelin restaurant is a perfect choice for discerning restaurant-goers seeking a new experience.

After enjoying a fulfilling meal, continue your evening at Scurreria Beer & Bagel, ideal for those looking to unwind with a drink in a comfortable setting. Alternatively, La Lepre offers a welcoming atmosphere for easing into the nightlife.

Raise a toast to the start of your 10-day luxury vacation in Italy and look forward to more fantastic days to come!

Wake up to day 2 of your luxury road trip holiday in Italy! Today, you will get the opportunity to visit multiple fantastic bucket-list destinations in the country as you head towards the city of Florence, where you'll be staying for 2 nights. The day's itinerary unfolds with a diverse array of experiences in Genoa.

Continue your road trip and head to your next destination, Florence. This car ride takes around 3 hours 2 min.

Make Chiesa di San Pietro in Banchi your first stop of the day. Previous visitors have rated this church an average of 4.6 out of 5 stars in 419 reviews.

Next up, make a stop at Aquarium of Genoa. With an average rating of 4.5 out of 5 stars by 62,259 visitors, it's easy to understand why so many people visit this public aquarium every year. In fact, this attraction welcomes 1,200,000 annual visitors.

Galata Museo del Mare (complex) is another attraction you can visit on this day of your vacation. This building complex has an average rating of 4.5 out of 5 stars by 8,322 visitors.

Relax and unwind in style as you spend the night at one of the top luxury hotels in in Florence.

Exploring new destinations can leave you craving great food and drinks. Satisfy your cravings and unwind by visiting the finest restaurants and bars in Florence.

Discover the culinary delights of Florence by securing a reservation at Enoteca Pinchiorri. Esteemed for its , this restaurant offers a remarkable selection of italian contemporary cuisine. For an alternative dining experience, try Santa Elisabetta, renowned for its delicious creative and mediterranean dishes. This esteemed 2-star Michelin-recipient consistently impresses guests, making it a must-visit spot during your holiday. Craving more culinary excitement? Head to Gucci Osteria da Massimo Bottura, a highly recommended local eatery celebrated for its mouthwatering italian contemporary and international menu. With its 1-star Michelin recognition, it offers an unforgettable dining adventure.

Cap off your culinary experience with a visit to some of the most celebrated bars in the area. For instance, Manifattura stands out as an excellent choice for a post-dinner cocktail. Alternatively, SE·STO on Arno Rooftop Bar offers an ideal atmosphere to enjoy the pleasures of the night. Archea Brewery is also a great option that provides a perfect setting for a relaxing evening.

Celebrate another great day of your luxury holiday in Italy with a toast! Enjoy a great night’s sleep at your lovely hotel and get ready for another fun day to come.

Day 3 of your luxury road trip in Italy begins and concludes in the city of Florence. Set out by car to explore incredible attractions in the nearby area. After a day filled with sightseeing, you'll return to Florence, where you still have 1 night nights remaining.

Make piazzale Michelangelo one of your first sightseeing stops in Florence. Rated an average of 4.8 out of 5 stars by 77,744 travelers, a visit to this local attraction makes for a great introduction to the area.

Uffizi Gallery is a worthwhile attraction you can visit next. This national museum is a valued place of interest in the area, with an average rating of 4.7 out of 5 stars from 61,794 reviews. Up to 2,011,219 travelers visit this site every year to make their time in Florence special.

Today is also the perfect opportunity to drop by Ponte Vecchio. This deck arch bridge has been rated an average of 4.7 out of 5 stars by 118,099 visitors.

If you’re keen to explore more, head to piazza della Signoria. A trip to this popular square is also your opportunity to see if it lives up to the reputable 4.8 out of 5-star rating as given by 66,956 previous visitors.

Another top place to visit is Cathedral of Santa Maria del Fiore. This church enjoys an average rating of 4.8 out of 5 stars from 76,359 local and international travelers.

In Florence, delicious dining experiences are never far from reach. Take your pick and consider whether you need to book a table in advance.

Reminisce about your day, look through photos, and prepare for another great day to come! Your luxury holiday in Italy has plenty more in store for you.

Wake up to day 4 of your luxury holiday in Italy! Remember to have a hearty breakfast because today will be filled with memorable adventures in Vatican City. With a flexible itinerary, you're free to adapt and explore additional attractions or enjoy spontaneous discoveries.

When you arrive in Vatican City, it's time to take a break from the road.

Make Sistine Chapel one of your first sightseeing stops in Vatican City. Rated an average of 4.7 out of 5 stars by 52,083 travelers, a visit to this local attraction makes for a great introduction to the area.

St. Peter's Basilica is a worthwhile attraction you can visit next. This major basilica is a valued place of interest in the area, with an average rating of 4.8 out of 5 stars from 131,043 reviews. Up to 11,000,000 travelers visit this site every year to make their time in Vatican City special.

Today is also the perfect opportunity to drop by Saint Peter's Square. This square has been rated an average of 4.8 out of 5 stars by 38,954 visitors.

If you’re keen to explore more, head to Vatican Museums and find out why 1,612,530 people visit this spot every year. A trip to this popular art museum is also your opportunity to see if it lives up to the reputable 4.6 out of 5-star rating as given by 133,310 previous visitors.

Relax and unwind in style as you spend the night at one of the top luxury hotels in in Rome.

After a long day of discovering the unique quirks of Italy, it’s an excellent idea to sit down for a lovely meal or enjoy a refreshing drink. We’ve gathered the most recommended dining and drinking spots in Rome so you can check out the menus and make advance reservations.

Start your culinary exploration in Rome by securing a reservation at La Pergola. This renowned restaurant holds , and offers an exceptional menu of mediterranean and contemporary cuisine. For another dining delight, visit Il Pagliaccio, celebrated for its delectable creative and innovative menu. This acclaimed 2-star Michelin-recipient consistently leaves guests satisfied, making it a must-visit during your holiday. Looking for a different experience? Discover Enoteca La Torre, a top local spot known for its tantalizing mediterranean and creative menu. With a 2-star Michelin recognition, it guarantees an exceptional dining adventure.

Continue the enjoyment post-dinner at La Botticella of Poggi Giovanni, a cherished local gathering spot renowned for its welcoming atmosphere. Similarly, Sant' Eustachio Caffè offers a vibrant space for indulging in well-crafted drinks and engaging conversation. You may also want to check out Caffè Portofino. This bar is a favorite among both locals and visitors looking for a delightful evening out filled with laughter and fun.

Raise your glass and relax after another big day of your luxury holiday in Italy!

Day 5 of your luxury road trip in Italy begins and concludes in the city of Rome. Set out by car to explore incredible attractions in the nearby area. After a day filled with sightseeing, you'll return to Rome, where you still have 3 nights nights remaining.

Make Orange Garden your first stop of the day. Previous visitors have rated this park an average of 4.7 out of 5 stars in 17,939 reviews.

Next up, make a stop at Circus Maximus. With an average rating of 4.4 out of 5 stars by 44,741 visitors, it's easy to understand why so many people visit this circus every year.

Campo de' Fiori is another attraction you can visit on this day of your vacation. This square has an average rating of 4.4 out of 5 stars by 51,133 visitors.

When you’re finished at Campo de' Fiori, the perfect next stop is Castel Sant'Angelo. This museum is rated an average of 4.7 out of 5 stars in 72,431 reviews. Castel Sant'Angelo attracts approximately 918,591 visitors annually.

If you’re keen to explore even more, then consider a visit to Belvedere del Gianicolo. This sightseeing destination is a top place to visit, with a rating of 4.6 out of 5 stars from 18,731 reviews.

After exploring the unique sights of Italy, savor a delicious meal or get refreshed with a drink. We’ve gathered the most recommended restaurants and bars in the city of Rome for you so you can browse their menus in advance and make a reservation.

Let the evening flow smoothly from dinner to drinks at The Apartment Bar Roma, a top-rated bar in the area. For other recommendations, Hotel Hassler Roma provides a perfect setting for rounding out your night with style and great drinks.

Celebrate another great day of your luxury holiday in Italy with a toast! Enjoy a great night’s sleep at your lovely hotel and get ready for another fun day to come.

Day 6 of your luxury road trip in Italy begins and concludes in the city of Rome. Set out by car to explore incredible attractions in the nearby area. After a day filled with sightseeing, you'll return to Rome, where you still have 2 nights nights remaining.

A top pick for your self-guided sightseeing tour today is Trevi Fountain. Previous visitors have rated this sculpture an average of 4.8 out of 5 stars in 343,494 reviews.

Piazza di Spagna is a local recommendation that you also can pay a visit today. This square is rated an average of 4.7 out of 5 stars in 113,658 reviews.

Another attraction you won't want to miss is Spanish Steps. This monumental staircase is rated an average of 4.5 out of 5 stars in 57,211 reviews.

Piazza del Popolo is another outstanding experience in Rome. Around 89,807 travelers have rated this square an average of 4.6 out of 5 stars.

If you long for more, Villa Borghese is not far away. This urban zone of rome is a lovely addition to your itinerary. Previous visitors have rated it an average of 4.6 out of 5 stars in 69,749 reviews.

After a long day of discovering the unique quirks of Italy, it’s an excellent idea to sit down for a lovely meal or enjoy a refreshing drink. We’ve gathered the most recommended dining and drinking spots in Rome so you can check out the menus and make advance reservations.

Reminisce about your day, look through photos, and prepare for another great day to come! Your stress-free luxury holiday in Italy has plenty more in store for you.

Day 7 of your luxury road trip in Italy begins and concludes in the city of Rome. Set out by car to explore incredible attractions in the nearby area. After a day filled with sightseeing, you'll return to Rome, where you still have 1 night nights remaining.

Begin your sightseeing with a visit to Basilica di Santa Maria Maggiore. This extraordinary major basilica is rated an average of 4.8 out of 5 stars by 27,678 visitors.

Next, make your way to Colosseum. This top attraction is a roman amphitheatre with an average rating of 4.7 out of 5 stars by 328,821 visitors. Colosseum welcomes 7,400,000 yearly visitors.

We also recommend a visit to Roman Forum. This square is rated 4.7 out of 5 stars by 114,450 travelers.

If you’re keen to keep exploring, visit Capitoline Hill. This highly recommended sightseeing destination has received an average rating of 4.7 out of 5 stars from 19,557 travelers.

Today is also your chance to spend some time at Altare della Patria. This architectural structure is rated an average of 4.8 out of 5 stars by 49,843 travelers. It’s estimated that 1,683,070 people visit this fantastic attraction every year.

Discover a world of culinary delights in Rome, where top-notch dining experiences await at every corner. Consider whether you need to make a reservation in advance to secure a table at your preferred restaurant.

Raise a toast to another amazing day of your luxury holiday in Rome, Italy and seize the opportunity to celebrate.

On day 8 of your luxury holiday in Italy, your road trip route will take you exploring the best of Rome. With a day brimming with amazing attractions ahead, fuel up with a hearty breakfast to savor every moment of your luxury vacation in Italy.

Pisa’s wonders await as you prepare for another journey on the road, leaving the breathtaking surroundings of Rome behind. This drive usually takes around 3 hours 44 min. Pisa welcomes you with a multitude of unique vacation experiences.

Begin your sightseeing with a visit to largo di Torre Argentina. This square is rated an average of 4.5 out of 5 stars in 30,433 reviews.

Next up, make your way to Pantheon. This roman temple has an average rating of 4.8 out of 5 stars from 189,682 reviews. Usually, around 30,000,000 people visit Pantheon every year.

When you’re ready for your next sight of the day, continue to Piazza Navona. This square has an average rating of 4.7 out of 5 stars from 158,771 visitors.

Beyond the above-mentioned attractions, you also have the opportunity to visit Foro Italico. This point of interest is rated an average of 4.6 out of 5 stars by 25,438 visitors.

Relax and unwind in style as you spend the night at one of the top luxury hotels in in Pisa.

After a day filled with travel and exploration, we recommend you treat yourself to a meal or a drink at the finest restaurants and bars in Pisa. Savor the local cuisine and relax as you recount the day's experiences.

With its reputation for pleasing customers, it’s a fantastic choice for tonight in Pisa.

Let the evening flow smoothly from dinner to drinks at JEFFER cocktails & friends, a top-rated bar in the area. For other recommendations, Le Parisien Wine Bar provides a perfect setting for rounding out your night with style and great drinks. Likewise, Las Volta cocktailbar offers a memorable night with diverse drink options and excellent service.

Reminisce about your day, look through photos, and prepare for another great day to come! Your stress-free luxury holiday in Italy has plenty more in store for you.

Wake up to day 9 of your luxury road trip holiday in Italy! Today, you will get the opportunity to visit multiple fantastic bucket-list destinations in the country as you head towards the city of Genoa, where you'll be staying for 1 night. The day's itinerary unfolds with a diverse array of experiences in Pisa and Corniglia.

Embrace the thrill of the open road as you wave goodbye to Pisa and set your GPS to Corniglia. While on the road, immerse yourself in your favorite road trip tunes or sample the sounds from a local radio station. This car ride usually takes around 1 hour 35 min. Upon reaching Corniglia, unwind, observe, and explore. The best things to do, see, and eat are waiting for you.

An excellent attraction to start your day with is Knights' Square. This square is rated an average of 4.5 out of 5 stars in 9,051 reviews.

Continue your journey at Leaning Tower of Pisa. This bell tower is rated 4.7 out of 5 stars by 116,882 travelers from near and far. Approximately 3,200,000 people come to this place of interest every year to enjoy a unique experience in Pisa.

Pisa is also the home of Piazza del Duomo, Pisa. This square has an average rating of 4.7 out of 5 stars from 104,550 visitors.

You can continue your self-guided sightseeing tour at Pisa Cathedral. Rated 4.8 out of 5 stars by 8,361 visitors, a visit to this top sight is time well spent.

Fasten your seatbelt and make your way to your next stop. Corniglia, home to many well-known sights in the region, is a lovely destination on today’s itinerary. Keep in mind that your travel time from Pisa to Corniglia may take around 1 hour 35 min without traffic disruptions. Upon arrival in Corniglia, we highly recommend checking out some of the top attractions.

Begin your sightseeing with a visit to Cinque Terre National Park. This extraordinary park is rated an average of 4.7 out of 5 stars by 43,526 visitors.

Relax and unwind in style as you spend the night at one of the top luxury hotels in in Genoa.

After exploring the unique sights of Italy, savor a delicious meal or get refreshed with a drink. We’ve gathered the most recommended restaurants and bars in the city of Genoa for you so you can browse their menus in advance and make a reservation.

As a top-rated it is an ideal choice in the city.

Raise a toast to another amazing day of your luxury holiday in Pisa, Italy and seize the opportunity to celebrate.

Today is the last day of your 10-day luxury holiday in Italy and it’s soon time to start your journey home. This is your chance to get one last glimpse of Genoa before saying goodbye.

On your last day in Italy, take time to indulge in shopping at Genoa’s popular marketplace. Thanks to your accommodation’s strategic location, the city’s bustling commercial district is only a stone’s throw away, giving you ample time to leisurely explore the area, filled with local shops.

Take time to find the perfect present, reminding you of the charms of Italy. Each store here is brimming with unique finds. These souvenirs will help you treasure your memories of Italy forever.

Treat yourself to a final feast. Savor the unique flavors of Genoa one last time before you head to the airport.

As a top-rated it is an ideal choice in the city. Enjoy a lovely meal at OVER SEA. , a top-rated place to have dinner tonight. Alternatively, if your taste buds call for something different, Osteria di Vico Palla is another top choice with a popular menu.

You will then say farewell to Genoa and begin your journey home. We wish you safe travels and a warm welcome home, with unforgettable memories and incredible photos from your luxury holiday in Italy in your luggage!