12-Day Italy Self-Drive Road Trip With Itinerary from Florence traveling south to Viterbo, Naples, Rome, and Siena

On day 2 of your road trip, you will have an entire day to explore Florence. You’ll stay in Florence for 1 night and discover all the best things to see and do in the area.

Discover a day packed with a charming, a mesmerizing, an eye-catching, a history-steeped, a detailed, and a culturally significant in Florence. Begin your sightseeing with The Boboli Gardens. This interesting botanical garden is one of the top attractions in the city. Proceed to Pitti Palace, another must-visit attraction that enhances the city’s allure.

As you wander through the inviting streets of Florence, soak in the lively ambiance and take the opportunity to snap some photos. Next, head to Ponte Vecchio. This timeless historical landmark is a traveler-favorite. Not far away, you’ll find Uffizi Gallery, another key site on your sightseeing itinerary. Conclude your day at Piazza Della Signoria and uncover why it's recognized as one of the city's most impressive attractions.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

After a day of adventure, treat yourself to an exquisite dinner at one of Florence's best restaurants.

Dive into a culinary adventure like no other in Florence by booking a table at Enoteca Pinchiorri. This popular restaurant holds 3 Michelin star and offers an exceptional menu of italian contemporary cuisine. For another culinary dining option, venture to Santa Elisabetta, celebrated for its delectable creative and mediterranean menu. This acclaimed 2-star Michelin-recipient consistently leaves guests satisfied, ensuring an essential addition to your holiday itinerary. Seeking an alternative? Discover Gucci Osteria da Massimo Bottura, a top local restaurant known for its tantalizing italian contemporary and international menu. With a 1-star Michelin recognition, it promises an exceptional dining experience not to be missed.

Explore the vibrant nightlife at Bar 50 Rosso after your meal, a hub for lively evenings and memorable moments. Or, head to Bitter Bar for a great selection of flavorful drinks and a charming setting. Furthermore, Archea Brewery is perfect for those looking to extend their night with a touch of local flavor.

Raise your glass and celebrate another amazing day of your road trip in Italy!

Embark on another extraordinary experience on day 3 of your road trip in Italy. Today, you will make 1 stop and experience some of the highlights of Florence. At the end of the day, you will enjoy the comforts of a top-rated hotel in Viterbo, which will be your home away from home for 1 night.

Brace yourself for today’s incredible lineup of attractions in Florence, featuring an instagrammable, a standout, an inviting, a grand, a charming, an awe-inspiring, an UNESCO world heritage-listed, and a remarkable. Start at Basilica Of Santa Croce In Florence, a well-known church in the city. Then, head to Cathedral Of Santa Maria Del Fiore and soak in the ambiance of this history-steeped church.

There are many interesting places to see in Florence and when you are ready for more, go to Galleria Dell'accademia. This is one of the city’s most popular spots. After exploring the art gallery, visit the notable David.

After soaking up all the sights of today's itinerary, you'll be ready to hit the road in the direction of your accommodation in Viterbo. Viterbo offers plenty of top-rated hotels and other places to stay on any travel budget. Take some time to relax before you head out to explore.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Viterbo. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Relax and recharge in preparation for another adventurous day in Italy!

On day 4 of your road trip in Italy, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Caserta and San Leucio-complex. In the evening, you’ll end up in Naples, where you will stay for 2 nights.

As you’ve unraveled the marvels of Viterbo, it’s time to gear up for the next part of your road trip adventure. Under favorable conditions, your drive to Caserta may take around 2 hours 53 min. Upon your arrival in Caserta, you’ll be greeted with the opportunity to do some sightseeing and exploring.

Savor the rest of your day by heading to Palace Of Caserta, a well-known palace that draws visitors from near and far. When you're done, continue on to Giardini Reali - Parco Reggia Di Caserta, where you can soak in the romantic surroundings. Next, explore Fountain Of Aeolus, yet another up-and-coming place to see in the area.

Admire the views and listen to some good music as you drive in the direction of San Leucio-complex.

Make your way to English Garden, an increasingly popular botanical garden that draws attention for its eye-catching features.

At the end of the day, you will drive to Naples, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Naples. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Enjoy an outstanding dining experience at Veritas, a 1-star Michelin restaurant offering an exceptional campanian and contemporary menu. If you are in the mood for trying an alternative dining experience, consider visiting the nearby 1-star Michelin-awardee, Il Comandante, known for its delicious creative and mediterranean cuisine. Another highly-recommended restaurant in Naples is ARIA, a renowned restaurant with a 1-star Guide Michelin recognition, known for its delicious contemporary and modern menu.

If you’re not ready to end the night just yet, Happening Cocktail Bar offers a perfect venue to relax and savor a drink. Similarly, Shanti Art Musik Bar is well-suited for those looking to unwind in a social setting. Gran Caffè Gambrinus is another excellent spot to enjoy a nightcap after a delightful meal.

Get a good night's sleep and look forward to another great day on the road in Italy!

Wake up to day 5 of your extraordinary road trip in Italy. With 1 night left in Naples, we encourage you to seize the day and discover the unexplored beauty of the city’s surroundings!

Brace yourself for today’s incredible lineup of attractions in Naples, featuring a romantic, a breathtaking, a photogenic, a historically significant, and a symbolic. Start at Piazza Del Plebiscito, an impressive public square in the village.

Continue your road trip and head to your next destination, Ravello. This car ride takes around 1 hour 10 min.

Take your self-guided tour to Villa Rufolo, a well-known historical landmark that everyone visiting Ravello should see. Enjoy sightseeing at your own pace and allow yourself time to explore the beautiful surroundings.

Set your GPS to Pompei and hit the road. Expect a journey of approximately 1 hour 1 min without stops. Soak in the beautiful landscapes as you drive and look forward to exploring your next destination. Pompei beckons with new experiences!

Spend your afternoon discovering Teatro Grande, an often recommended archeological site known for its historic features. After taking in the atmosphere, continue to Archaeological Park Of Pompeii, a captivating archeological site that is a must-see for anyone visiting the region. Next, stop by Amphitheatre Of Pompeii and uncover the details of this culturally significant archeological site.

When you’re done exploring for the day, you’ll return to Naples and your accommodation.

As dinnertime approaches, it's time to head out for a bite to eat in Naples. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Make sure to reserve a table at Antica Pizzeria Di Matteo, an iconic dining spot in Naples. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Mercure Napoli Centro Angioino, a popular restaurant in Naples. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of La Lazzara Trattoria e Pizzeria, a hidden gem nestled in Naples. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Extend your evening after a delightful meal by visiting Archivio Storico - Cocktail Bar & Wonderfood, which offers the perfect atmosphere for a night out. Moreover, Archeobar is another popular option for a drink or two. Likewise, Babette Pub also provides a great ambiance for reminiscing about the day and raising a toast to your vacation.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in in Italy.

Dive into day 6 of your remarkable road trip in Italy. Today you will explore Naples, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Rome. You’ll stay here for 4 nights.

Immerse yourself in Naples’s rich culture with today's sightseeing itinerary. Start your journey at Castel Nuovo. This historic castle is sure to ignite your curiosity. Next, dive into the noteworthy features of Naples National Archaeological Museum, a must-visit museum in the city.

In between sights, stop by local stores, picturesque photo spots, and small eateries. When you’re ready for your next attraction, proceed to Ovo Castle, an interesting castle. For a change of scene, check out Piazza Vincenzo Bellini, known for its instagrammable features.

When you’re done exploring for the day, you’ll drive to your hotel in Rome. Check in and spend some time relaxing before you head out to tour the city.

As dinnertime approaches, it's time to head out for a bite to eat in Rome. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Dive into a culinary adventure like no other in Rome by booking a table at La Pergola. This popular restaurant holds 3 Michelin star and offers an exceptional menu of mediterranean and contemporary cuisine. For another culinary dining option, venture to Il Pagliaccio, celebrated for its delectable creative and innovative menu. This acclaimed 2-star Michelin-recipient consistently leaves guests satisfied, ensuring an essential addition to your holiday itinerary. Seeking an alternative? Discover Enoteca La Torre, a top local restaurant known for its tantalizing mediterranean and creative menu. With a 2-star Michelin recognition, it promises an exceptional dining experience not to be missed.

Cap off your dinner by heading to La Botticella Of Poggi Giovanni, ideal for a leisurely evening with a drink in hand. Almalu Trastevere is another bar that offers an enjoyable setting. Similarly, Bar Viminale Di Pepi Maurilio is also a popular place to go on a night out, perfect for relaxing and socializing.

Take some time to reflect on your day and savor another beautiful night in Italy.

Day 7 of your road trip across Italy promises a magnificent time exploring Rome. You have 3 nights left in Rome. Take the opportunity to experience more of the best attractions and activities in the city.

Start by visiting Castel Sant'angelo, a prime spot to begin your journey. This visually striking castle is sure to impress. Next on your list is Piazza Navona, another must-visit landmark and wondrous public square renowned for its noteworthy features.

While exploring and sightseeing, take time to savor the ambiance of Rome by sampling some local delicacies or having a drink. When you’re ready for more sightseeing, head to Pantheon. This photogenic monument is a remarkable attraction that offers a unique experience. Piazza Del Popolo also adds charm to your journey, and Villa Borghese wraps up your day with its serene appeal.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Rome. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Dine in style at RomAntica, a top recommendation for dinner tonight. Or, for a change of pace, Coso Ristorante boasts a menu that's sure to impress. Also, be sure to check out DEROMA - Farine Romane. Known as a local hotspot, it’s a great choice for tonight in Rome.

After savoring a delicious meal, step into the vibrant nightlife at Sant' Eustachio Caffè, where the evening is just getting started. In the same way, Yellowsquare Rome offers a unique charm perfect for experiencing the local bar scene in Rome. Caffè Portofino is another top-recommended bar that is sure to get you into the mood for some dancing and celebrating.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in in Italy.

Day 8 offers a multitude of experiences. You will stay in Rome for 2 nights more, offering you enough time to explore at a relaxed pace.

Brace yourself for today’s incredible lineup of attractions in Rome, featuring a gorgeous, a visually striking, a respected, a grand, an UNESCO world heritage-listed, and a romantic. Start at Circus Maximus, a popular archeological site in the city. Then, head to Colosseum and soak in the ambiance of this UNESCO world heritage-listed archeological site.

There are many interesting places to see in Rome and when you are ready for more, go to Roman Forum. This is one of the city’s most timeless spots. After exploring the archeological site, visit the well-known Largo Di Torre Argentina. Before wrapping up your self-guided sightseeing tour, head to the spectacular Campo De' Fiori, a spectacular public square in the city.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

Indulge in a memorable dining experience at one of Rome's most popular restaurants, and connect with friendly locals for an authentic adventure.

Treat yourself to a delicious dinner at Hotel de Russie, an excellent option for tonight's dining. Looking for something different? La Taverna Italiana offers a tantalizing alternative with its diverse menu. And don’t miss The Parrot Bar. With its reputation for pleasing customers, it’s a fantastic choice for tonight in Rome.

To truly maximize your evening out, consider visiting The Apartment Bar Roma after dinner. This bar is known for offering some of the best drinks and vibes in the city. Alternatively, head to Hotel Hassler Roma, another bar with an inviting ambiance.

Relax and recharge in preparation for another adventurous day in Italy!

Day 9 of your road trip will take you to the best attractions Rome has to offer. Cherish the 1 night you have left in Rome by discovering the best things there are to see and do in the city.

Whether you prefer a leisurely exploration or a more fast-paced adventure, this itinerary in Rome allows for both. Start by heading to Basilica Di Santa Maria Maggiore. This captivating church provides an insightful glimpse into the city's identity. Next, discover Altare Della Patria, a culturally significant monument, promising a delightful encounter.

Continue your sightseeing with a visit to Piazza Di Spagna, an iconic public square. When you’re done, don’t forget to make a stop at the impressive Spanish Steps.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Rome. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Treat yourself to a delightful dinner at Sofitel Roma Villa Borghese, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Centro? It's another excellent option with a diverse menu. Consider reserving a table at Ristorante Tema as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Rome.

Say good night to Rome and look forward to another great day of your road trip in Italy!

Experience an unparalleled adventure on day 10 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 1 vibrant destinations - Vatican City. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Siena. You will spend 1 night here for some well-deserved relaxation.

Once you're ready to continue your road trip, it's time to buckle up and drive towards Vatican City, eagerly anticipating your arrival in Vatican City. This drive usually takes around 11 min, without any stops or traffic disruptions.

Head to St. Peter's Basilica, a wondrous major basilica in Vatican City. This extraordinary chapel is a top recommendation in the area. When you’re ready to explore more, Saint Peter's Square is an excellent choice. Next, continue your sightseeing at the iconic Vatican Museums and discover what makes this art museum unique.

After soaking up all the sights of today's itinerary, you'll be ready to hit the road in the direction of your accommodation in Siena. Siena offers plenty of top-rated hotels and other places to stay on any travel budget. Take some time to relax before you head out to explore.

As you explore more of Siena, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Make sure to reserve a table at Enoteca I Terzi, an iconic dining spot in Siena. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Ristorante Tar-Tufo, a popular restaurant in Siena. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Antica Trattoria Papei, a hidden gem nestled in Siena. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

After enjoying a fulfilling meal, continue your evening at Meet Life Cafè, ideal for those looking to unwind with a drink in a comfortable setting. Alternatively, Maudit Pub offers a welcoming atmosphere for easing into the nightlife. Similarly, Bar Impero Siena provides an excellent environment for a relaxed and enjoyable evening.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in in Italy.

On day 11 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 2 destinations, Siena and Pisa. When you’re not sightseeing, take time to relax at your selected hotel in Florence, where you’ll be staying for 1 night.

Siena is home to plenty of attractions that offer a romantic, a gorgeous, a picture-perfect, a historically significant, an UNESCO world heritage-designated, a sacred, and a majestic! Start at Piazza Del Campo, an astonishing public square that is worthwhile a visit in the city. Nearby, you’ll find Siena Cathedral, enchanting visitors with its inviting appeal.

Pisa’s wonders await as you prepare for another journey on the road, leaving the breathtaking surroundings of Siena behind. This drive usually takes around 1 hour 50 min. Pisa welcomes you with a multitude of unique vacation experiences.

Spend your afternoon discovering Leaning Tower Of Pisa, a wondrous monument known for its culturally significant features. After taking in the atmosphere, continue to Piazza Del Duomo, Pisa, a world-famous public square that is a must-see for anyone visiting the region. Next, stop by Campo Santo and uncover the details of this picture-perfect cemetery.

At the end of the day, you will drive to Florence, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

Indulge in a memorable dining experience at one of Florence's most popular restaurants, and connect with friendly locals for an authentic adventure.

Treat yourself to a delicious dinner at Ristorante Buca Mario, an excellent option for tonight's dining. Looking for something different? Agricola Toscana offers a tantalizing alternative with its diverse menu. And don’t miss Eataly Firenze. With its reputation for pleasing customers, it’s a fantastic choice for tonight in Florence.

Round off your dining experience by visiting Gosh*, a prime location for a drink. Alternatively, explore the distinctive characteristics of Antico Caffè Del Moro - Art Bar Firenze, a bar catering to every mood and preference. Quelo Bar likewise offers a unique atmosphere, perfect for a memorable night out.

Savor another day of unforgettable experiences in Italy!