Luxury 12-Day Italy Road Trip from Milan traveling south to Genoa, Florence, Arezzo, Rome, Siena, Venice, and Verona

Your luxury holiday in Italy begins as soon as you reach the city of Milan, where you'll be staying for 1 night. There, you’ll pick up the luxury rental vehicle of your choice and hit the roads!

When you're ready to see some sights, Piazza Gae Aulenti is a great place to start. This square is rated an average of 4.6 out of 5 stars by 30,398 visitors.

Tonight, you will be treated to a stay at one of the best luxury hotels in Milan. We have picked out three of the most exclusive luxury lodging and hotel options for you to choose from.

After a long day of discovering the unique quirks of Italy, it’s an excellent idea to sit down for a lovely meal or enjoy a refreshing drink. We’ve gathered the most recommended dining and drinking spots in Milan so you can check out the menus and make advance reservations.

Have a memorable dining experience in Milan by booking a table at Enrico Bartolini al Mudec, renowned as a 3-star Michelin restaurant presenting an exceptional creative menu. For a different culinary experience, Seta by Antonio Guida shines as one of the top destinations known for its delicious international and contemporary cuisine in Milan. This 2-star Michelin-awardee earns consistently high praises from previous guests, making it a must-visit addition to your holiday experience. If you're looking for an alternative, Il Luogo Aimo e Nadia is known as a top local spot for its delicious italian contemporary and modern cuisine in Milan. This 1-star Michelin awardee is a highly recommended choice for an unforgettable meal.

After enjoying a fulfilling meal, continue your evening at Nottingham Forest, ideal for those looking to unwind with a drink in a comfortable setting. Alternatively, Armani/Bamboo Bar offers a welcoming atmosphere for easing into the nightlife. Similarly, Mag Cafe provides an excellent environment for a relaxed and enjoyable evening.

Raise a toast to the start of your 12-day luxury vacation in Italy and look forward to more fantastic days to come!

Wake up to day 2 of your luxury road trip holiday in Italy! Today, you will get the opportunity to visit multiple fantastic bucket-list destinations in the country as you head towards the city of Genoa, where you'll be staying for 1 night. The day's itinerary unfolds with a diverse array of experiences in Milan.

Drop by the renowned Duomo di Milano Museum. This popular art museum has been rated an average of 4.8 out of 5 stars by 138,554 visitors. Based on recent data, this attraction is visited by more than 341,609 travelers every year.

Another unforgettable place to experience is Galleria Vittorio Emanuele II. Rated 4.7 out of 5 stars by 91,394 visitors, this commercial gallery deserves a spot on today's sightseeing itinerary.

We also recommend a visit to La Scala. This opera house has been rated an average of 4.7 out of 5 stars in 26,219 reviews.

Another favorite attraction in the area is Sforzesco Castle Art Library. This library and popular place of interest enjoys a rating of 4.6 out of 5 stars from 68,714 local and international travelers.

If you’re keen to explore even more, then consider a visit to Parco Sempione. With an average rating of 4.6 out of 5 stars from 72,914 travelers, this park is an attraction many avid travelers highly recommend visiting while in Milan.

Relax and unwind in style as you spend the night at one of the top luxury hotels in in Genoa.

After exploring the unique sights of Italy, savor a delicious meal or get refreshed with a drink. We’ve gathered the most recommended restaurants and bars in the city of Genoa for you so you can browse their menus in advance and make a reservation.

Prepare for an extraordinary culinary adventure in Genoa by booking a table at The Cook, a 1-star Michelin restaurant that boasts an exceptional modern menu. For a different flavor experience, head to San Giorgio, renowned for its delectable modern and ligurian dishes. This 1-star Michelin restaurant consistently wows guests, making it a memorable stop during your holiday. Looking for another option? Visit Il Marin, a local gem known for its delightful seafood and contemporary cuisine in Genoa. Nestled in the city's heart, this 1-star Michelin restaurant is a perfect choice for discerning restaurant-goers seeking a new experience.

After enjoying a delightful dinner, why not delve into the vibrant local bar scene? You might want to spend the evening at Scurreria Beer & Bagel, a well-loved spot among locals and tourists. Or, head to La Lepre. This bar boasts a welcoming environment that is perfect for winding down.

Raise a toast to another amazing day of your luxury holiday in Milan, Italy and seize the opportunity to celebrate.

On day 3 of your luxury holiday in Italy, your road trip route will take you exploring the best of Genoa and Pisa. With a day brimming with amazing attractions ahead, fuel up with a hearty breakfast to savor every moment of your luxury vacation in Italy.

When you're ready to see some sights, piazza De Ferrari is a great place to start. This square is rated an average of 4.6 out of 5 stars by 34,312 visitors.

Another popular attraction you can visit today is Aquarium of Genoa. This public aquarium has an average rating of 4.5 out of 5 stars from 62,259 travelers. Every year, 1,200,000 travelers come to experience this site to make the most of their time in Genoa.

As you’ve unraveled the marvels of Genoa, it’s time to gear up for the next part of your road trip adventure. Under favorable conditions, your drive to Pisa may take around 2 hours 5 min. Upon your arrival in Pisa, you’ll be greeted with the opportunity to do some sightseeing and exploring.

Begin your sightseeing with a visit to Leaning Tower of Pisa. This extraordinary bell tower is rated an average of 4.7 out of 5 stars by 116,882 visitors. Each year, around 3,200,000 people visit this site to learn more about it.

Next, make your way to Piazza del Duomo, Pisa. This top attraction is a square with an average rating of 4.7 out of 5 stars by 104,550 visitors.

Relax and unwind in style as you spend the night at one of the top luxury hotels in in Florence.

In Florence, delicious dining experiences are never far from reach. Take your pick and consider whether you need to book a table in advance.

Experience a harmony of flavors at Enoteca Pinchiorri in Florence by securing a reservation in advance. Known for its 3-star Michelin status, Enoteca Pinchiorri offers a delightful variety of dishes highlighting its delicious italian contemporary menu. If you're seeking an alternative culinary experience, be sure to explore Santa Elisabetta, a highly recommended restaurant known for its enticing creative and mediterranean cuisine. This popular 2-star Michelin-awarded venue consistently exceeds expectations, ensuring a memorable holiday experience. Ready for another culinary adventure? Indulge your senses at Gucci Osteria da Massimo Bottura, a highly acclaimed restaurant celebrated for its exceptional italian contemporary and international menu.

Continue your lively evening at Manifattura, a perfect place for winding down or revving up the night, depending on which mood you’re in. SE·STO on Arno Rooftop Bar is another excellent bar that offers a great selection of drinks to suit any mood. If you prefer to go somewhere else, Archea Brewery ensures a night out tailored to your taste.

Reminisce about your day, look through photos, and prepare for another great day to come! Your stress-free luxury holiday in Italy has plenty more in store for you.

Wake up to day 4 of your luxury holiday in Italy! Remember to have a hearty breakfast because today will be filled with memorable adventures in Florence. With a flexible itinerary, you're free to adapt and explore additional attractions or enjoy spontaneous discoveries.

Make piazza della Signoria your first stop of the day. Previous visitors have rated this square an average of 4.8 out of 5 stars in 66,956 reviews.

Next up, make a stop at Cathedral of Santa Maria del Fiore. With an average rating of 4.8 out of 5 stars by 76,359 visitors, it's easy to understand why so many people visit this church every year.

Ponte Vecchio is another attraction you can visit on this day of your vacation. This deck arch bridge has an average rating of 4.7 out of 5 stars by 118,099 visitors.

When you’re finished at Ponte Vecchio, the perfect next stop is Uffizi Gallery. This national museum is rated an average of 4.7 out of 5 stars in 61,794 reviews. Uffizi Gallery attracts approximately 2,011,219 visitors annually.

If you’re keen to explore even more, then consider a visit to piazzale Michelangelo. This square is a top place to visit, with a rating of 4.8 out of 5 stars from 77,744 reviews.

Relax and unwind in style as you spend the night at one of the top luxury hotels in in Arezzo.

Discover a world of culinary delights in Arezzo, where top-notch dining experiences await at every corner. Consider whether you need to make a reservation in advance to secure a table at your preferred restaurant.

Treat yourself to an extraordinary dining experience at Octavin, a 1-star Michelin restaurant offering an incredible creative menu. As a top-rated it is an ideal choice in the city.

Explore the vibrant nightlife at Liquid Bar after your meal, a hub for lively evenings and memorable moments.

Reminisce about your day, look through photos, and prepare for another great day to come! Your luxury holiday in Italy has plenty more in store for you.

Wake up to day 5 of your luxury road trip holiday in Italy! Today, you will get the opportunity to visit multiple fantastic bucket-list destinations in the country as you head towards the city of Rome, where you'll be staying for 3 nights. The day's itinerary unfolds with a diverse array of experiences in Vatican City.

Upon your arrival in Vatican City, you’ll be greeted with the opportunity to do some sightseeing and exploring.

Seize the day by visiting some of the best attractions in the area, like Vatican Museums. This extraordinary art museum has an average rating of 4.6 out of 5 stars from 133,310 visitors. Each year, around 1,612,530 people visit this remarkable site to admire its features and learn more about it.

Next, make your way to Saint Peter's Square. This square is rated an average of 4.8 out of 5 stars in 38,954 reviews.

While in Vatican City, we also recommend a visit to Sistine Chapel. This chapel has been rated an average of 4.7 out of 5 stars in 52,083 reviews.

If you’re keen to explore even more, then consider a visit to St. Peter's Basilica. This attraction gets around 11,000,000 yearly visitors. With an average rating of 4.8 out of 5 stars by 131,043 travelers, this major basilica is a highly recommended stop on your sightseeing around Vatican City.

Relax and unwind in style as you spend the night at one of the top luxury hotels in in Rome.

After a long day of exploring, it’s a great idea to relax with a lovely dinner or a refreshing drink. We’ve gathered the most recommended dining and drinking spots in Rome for you, so you can check out the menus and make your reservation in advance.

Set out on a gastronomic journey in Rome by reserving a table at La Pergola. Renowned for its , this restaurant presents an outstanding menu of mediterranean and contemporary cuisine. For a different taste, head over to Il Pagliaccio, renowned for its delectable creative and innovative dishes. This distinguished 2-star Michelin-recipient is a favorite among guests, making it a worthy addition to your holiday plans. Craving more culinary excitement? Explore Enoteca La Torre, a highly rated local gem known for its exquisite mediterranean and creative menu. With a 2-star Michelin acclaim, it promises a dining experience you won't want to miss. With its reputation for pleasing customers, it’s a fantastic choice for tonight in Rome.

Keep the evening going at La Botticella of Poggi Giovanni, a great choice for enjoying the after-dinner hours with a drink. You could also go to Sant' Eustachio Caffè, which offers a similarly pleasant setting and great drinks. Another option is Caffè Portofino, which provides an inviting environment for unwinding after a busy day out.

Raise your glass and relax after another big day of your luxury holiday in Italy!

Day 6 of your luxury road trip in Italy begins and concludes in the city of Rome. Set out by car to explore incredible attractions in the nearby area. After a day filled with sightseeing, you'll return to Rome, where you still have 2 nights nights remaining.

Make Colosseum one of your first sightseeing stops in Rome. Rated an average of 4.7 out of 5 stars by 328,821 travelers, a visit to this local attraction makes for a great introduction to the area. This roman amphitheatre attracts 7,400,000 visitors every year.

Roman Forum is a worthwhile attraction you can visit next. This square is a valued place of interest in the area, with an average rating of 4.7 out of 5 stars from 114,450 reviews.

Today is also the perfect opportunity to drop by Capitoline Hill. This hill has been rated an average of 4.7 out of 5 stars by 19,557 visitors.

If you’re keen to explore more, head to Altare della Patria and find out why 1,683,070 people visit this spot every year. A trip to this popular architectural structure is also your opportunity to see if it lives up to the reputable 4.8 out of 5-star rating as given by 49,843 previous visitors.

Another top place to visit is Circus Maximus. This circus enjoys an average rating of 4.4 out of 5 stars from 44,741 local and international travelers.

After a long day of exploring, it’s a great idea to relax with a lovely dinner or a refreshing drink. We’ve gathered the most recommended dining and drinking spots in Rome for you, so you can check out the menus and make your reservation in advance.

After your delicious meal, get a taste of the vibrant nightlife with a visit to The Apartment Bar Roma, known for its inviting atmosphere. Hotel Hassler Roma is another great option if you’re looking for a place to get the night started.

Reminisce about your day, look through photos, and prepare for another great day to come! Your luxury holiday in Italy has plenty more in store for you.

Day 7 of your luxury road trip in Italy begins and concludes in the city of Rome. Set out by car to explore incredible attractions in the nearby area. After a day filled with sightseeing, you'll return to Rome, where you still have 1 night nights remaining.

Your sightseeing of the day begins at Trevi Fountain, a remarkable sculpture where it’s easy to get lost in exploration. This top attraction is rated an average of 4.8 out of 5 stars in 343,494 reviews.

Next, satisfy your wanderlust at Piazza di Spagna. This square has an average rating of 4.7 out of 5 stars from 113,658 travelers.

Spanish Steps is another must-visit attraction. This renowned monumental staircase offers a memorable experience, well worth a stop on your self-guided sightseeing tour. Rated 4.5 out of 5 stars by 57,211 travelers, it's one of the more popular places to see in the area.

Beyond the above-mentioned sites, you also have the opportunity to visit piazza del Popolo. This well-loved square boasts a 4.6 out of 5-star rating from 89,807 reviews.

When there’s still energy left for exploring, Villa Borghese awaits. If you’ve been interested in experiencing an urban zone of rome, this is a top pick rated 4.6 out of 5 stars by 69,749 previous visitors.

In Rome, delicious dining experiences are never far from reach. Take your pick and consider whether you need to book a table in advance.

As a top-rated it is an ideal choice in the city.

Raise your glass and relax after another big day of your luxury holiday in Italy!

On day 8 of your luxury holiday in Italy, your road trip route will take you exploring the best of Rome. With a day brimming with amazing attractions ahead, fuel up with a hearty breakfast to savor every moment of your luxury vacation in Italy.

Be one of the day’s first visitors at largo di Torre Argentina. This square is rated an average of 4.5 out of 5 stars by 30,433 visitors.

When you’re finished at largo di Torre Argentina, head to Pantheon. This one-of-a-kind roman temple is rated an average of 4.8 out of 5 stars in 189,682 reviews. Every year, approximately 30,000,000 travelers come here to experience the roman temple for themselves.

Beyond the above-mentioned attractions, you also have the opportunity to visit Piazza Navona. This square is rated an average of 4.7 out of 5 stars by 158,771 visitors.

If you’re keen to explore more, then consider a visit to Campo de' Fiori. This square is a much-appreciated attraction with an average rating of 4.4 out of 5 stars from 51,133 visitors.

To round off your sightseeing experience, make your way to Castel Sant'Angelo. This famous museum welcomes around 918,591 visitors annually and is rated an average of 4.7 out of 5 stars by 72,431 travelers.

Relax and unwind in style as you spend the night at one of the top luxury hotels in in Siena.

Treat yourself after a day of exploration. Make a reservation at the finest dining and drinking spots in Siena.

Keep the excitement of the evening going by going to a bar or two. Meet Life Cafè is an excellent place to start. You could also check out Maudit Pub, offering a different kind of charm. A last recommendation for the day is Bar Impero Siena. This bar promises an enjoyable experience with tasty drinks and a vibrant setting.

Celebrate another great day of your luxury holiday in Italy with a toast! Enjoy a great night’s sleep at your lovely hotel and get ready for another fun day to come.

Wake up to day 9 of your luxury holiday in Italy! Remember to have a hearty breakfast because today will be filled with memorable adventures in Siena and Bologna. With a flexible itinerary, you're free to adapt and explore additional attractions or enjoy spontaneous discoveries.

An excellent attraction to start your day with is Tower of Mangia. This sightseeing destination is rated an average of 4.6 out of 5 stars in 673 reviews.

Continue your journey at piazza del Campo. This square is rated 4.8 out of 5 stars by 64,175 travelers from near and far.

Siena is also the home of Siena Cathedral. This domus has an average rating of 4.8 out of 5 stars from 21,656 visitors.

When you’re ready to jump back into the car and say goodbye to Siena, you’ll hit the road in the direction of Bologna. This drive usually takes around 1 hour 56 min. When you arrive, enjoy some sightseeing.

Take the opportunity to see Ducati Museum. This attraction has an average rating of 4.5 out of 5 stars from 4,028 visitors and gets around 7,600 visits every year.

Relax and unwind in style as you spend the night at one of the top luxury hotels in in Venice.

After a full day of exploring, treat yourself to a delightful dinner or a refreshing drink at the best spots in Venice. Choose from a selection of excellent restaurants and bars and find the perfect place for your evening.

Experience a symphony of flavors at Local in Venice by securing a reservation in advance. Renowned for its 1-star Michelin distinction, Local delights its guests with its exceptional variety of meals showcasing delicious contemporary cuisine. For a palate-pleasing alternative, make sure to dine at Wistèria, acclaimed for its delectable contemporary and venetian specialties. This local 1-star Michelin establishment consistently satisfies guests, ensuring an unforgettable holiday experience. Want to go on another culinary journey? Delight your senses at Quadri, a top-rated restaurant known for its outstanding menu. Known as a top-rated , it's a top choice for modern cuisine in the city.

After your delicious meal, get a taste of the vibrant nightlife with a visit to Al Parlamento, known for its inviting atmosphere. Adagio is another great option if you’re looking for a place to get the night started. Similarly, Il Mercante provides a great setting to enjoy the night away.

Raise a toast to another amazing day of your luxury holiday in Siena, Italy and seize the opportunity to celebrate.

Wake up to day 10 of your luxury road trip holiday in Italy! Today, you will get the opportunity to visit multiple fantastic bucket-list destinations in the country as you head towards the city of Verona, where you'll be staying for 1 night. The day's itinerary unfolds with a diverse array of experiences in Venice.

Start your sightseeing with a visit to Rialto Bridge. This stone bridge is rated an average of 4.7 out of 5 stars from 141,666 visitors.

Piazza San Marco is another popular attraction you could visit today. This square has a rating of 4.7 out of 5 stars from 152,982 visitors.

St Mark's Basilica is also highly recommended by travelers. This cathedral has a rating of 4.7 out of 5 stars from 18,439 visitors.

Doge's Palace is an attraction you won’t want to miss. Around 318,104 people visit this place every year. This palace is rated an average of 4.7 out of 5 stars in 24,775 reviews.

Another attraction you have the opportunity to visit today is Bridge of Sighs. This footbridge has received an average rating of 4.6 out of 5 stars from 18,223 travelers.

Relax and unwind in style as you spend the night at one of the top luxury hotels in in Verona.

After a long day of discovering the unique quirks of Italy, it’s an excellent idea to sit down for a lovely meal or enjoy a refreshing drink. We’ve gathered the most recommended dining and drinking spots in Verona so you can check out the menus and make advance reservations.

Experience a taste of local culinary excellence while in Verona by securing a table at Casa Perbellini 12 Apostoli. Esteemed as a 2-star Michelin restaurant, it features an exceptional creative and contemporary menu. For an alternative taste experience, visit Il Desco, famous for its scrumptious italian contemporary dishes. This 1-star Michelin venue consistently impresses guests, making it a standout addition to your holiday plans. Looking for another choice? Discover Osteria Mondo d'Oro, a local favorite celebrated for its exquisite italian and seasonal cuisine in Verona. Located in the heart of the city, this Bib Gourmand-awardee is an ideal pick for italian and seasonal cuisine lovers seeking top-notch culinary experiences.

Following your dinner, dive into the local bar culture at Archivio. Alternatively, go to La Segreteria Café, the perfect place for those looking to experience the best of the nightlife. Similarly, Duchi Café provides excellent drinks and a great atmosphere, ensuring a memorable night out.

Reminisce about your day, look through photos, and prepare for another great day to come! Your stress-free luxury holiday in Italy has plenty more in store for you.

On day 11 of your luxury holiday in Italy, your road trip route will take you exploring the best of Verona and Ronchi. With a day brimming with amazing attractions ahead, fuel up with a hearty breakfast to savor every moment of your luxury vacation in Italy.

Begin your sightseeing with a visit to Porta Borsari. This city gate is rated an average of 4.6 out of 5 stars in 5,387 reviews.

Next up, make your way to Verona Arena. This opera house has an average rating of 4.7 out of 5 stars from 123,818 reviews. Usually, around 195,540 people visit Verona Arena every year.

Set your GPS to Ronchi and hit the road. Expect a journey of approximately 35 min without stops. Soak in the beautiful landscapes as you drive and look forward to exploring your next destination. Ronchi beckons with new experiences!

Drop by the renowned Gardaland Resort. This popular amusement park has been rated an average of 4.4 out of 5 stars by 99,291 visitors.

Relax and unwind in style as you spend the night at one of the top luxury hotels in in Milan.

Exploring new destinations can leave you craving great food and drinks. Satisfy your cravings and unwind by visiting the finest restaurants and bars in Milan.

After your meal, keep the night alive at a bar like Kilburn Cocktail Bar Milano, known for its lively atmosphere. Bar Frida is another top recommendation that provides the perfect setting with well-crafted drinks and a welcoming ambiance. Similarly, The Friends Pub Milano offers an excellent atmosphere for those looking to amp up the evening.

Reminisce about your day, look through photos, and prepare for another great day to come! Your luxury holiday in Italy has plenty more in store for you.

Today is the last day of your 12-day luxury holiday in Italy and it’s soon time to start your journey home. This is your chance to get one last glimpse of Milan before saying goodbye.

Maximize your last day in Italy and go on a shopping spree in Milan’s shopping center. This bustling commercial district is conveniently located near your lodging, granting you leisure time to roam and explore its assortment of establishments.

If you love the adrenaline rush of hunting for the best offers and deals in Italy, you’re in for a treat. A variety of goods and gifts await your discovery. Bring a bit of Italy home with you through these charming souvenirs.

Make the most of what's left of your luxury vacation and head out to the stunning Arch of Peace. This extraordinary monument and attraction is rated an average of 4.6 out of 5 stars in 27,502 reviews, and is an excellent choice for your last sightseeing in Milan.

Treat yourself to a final feast. Savor the unique flavors of Milan one last time before you head to the airport.

Treat yourself to a delicious dinner at Vento di Sardegna, an excellent option for tonight's dining. Looking for something different? Palazzo Parigi Hotel & Grand Spa Milano offers a tantalizing alternative with its diverse menu. And don’t miss Galleria Restaurant.

You will then say farewell to Milan and begin your journey home. We wish you safe travels and a warm welcome home, with unforgettable memories and incredible photos from your luxury holiday in Italy in your luggage!