Luxury 13-Day Italy Road Trip from Pisa traveling east to Arezzo, Rome, Province of Salerno, Naples, L'aquila, Perugia, and Florence

Your luxury holiday in Italy begins as soon as you reach the city of Pisa. There, you’ll pick up the luxury rental vehicle of your choice and hit the roads!

Your sightseeing of the day begins at Knights' Square, a remarkable square where it’s easy to get lost in exploration. This top attraction is rated an average of 4.5 out of 5 stars in 9,051 reviews.

Tonight, you will be treated to a stay at one of the best luxury hotels in Pisa. We have picked out three of the most exclusive luxury lodging and hotel options for you to choose from.

Exploring new destinations can leave you craving great food and drinks. Satisfy your cravings and unwind by visiting the finest restaurants and bars in Pisa.

After enjoying a delightful dinner, why not delve into the vibrant local bar scene? You might want to spend the evening at JEFFER cocktails & friends, a well-loved spot among locals and tourists. Or, head to Le Parisien Wine Bar. This bar boasts a welcoming environment that is perfect for winding down. You could also continue your night at Las Volta cocktailbar, another top-rated place in the area.

Raise a toast to the start of your 13-day luxury vacation in Italy and look forward to more fantastic days to come!

Wake up to day 2 of your luxury road trip holiday in Italy! Today, you will get the opportunity to visit multiple fantastic bucket-list destinations in the country as you head towards the city of Arezzo, where you'll be staying for 1 night. The day's itinerary unfolds with a diverse array of experiences in Pisa and Tirrenia.

Begin your sightseeing with a visit to Leaning Tower of Pisa. This extraordinary bell tower is rated an average of 4.7 out of 5 stars by 116,882 visitors. Each year, around 3,200,000 people visit this site to learn more about it.

Next, make your way to Piazza del Duomo, Pisa. This top attraction is a square with an average rating of 4.7 out of 5 stars by 104,550 visitors.

We also recommend a visit to Pisa Cathedral. This cathedral is rated 4.8 out of 5 stars by 8,361 travelers.

Upon reaching Tirrenia, unwind, observe, and explore. The best things to do, see, and eat are waiting for you.

Your sightseeing of the day begins at Bagno degli Americani, a remarkable sightseeing destination where it’s easy to get lost in exploration. This top attraction is rated an average of 4.2 out of 5 stars in 2,992 reviews.

Relax and unwind in style as you spend the night at one of the top luxury hotels in in Arezzo.

After a full day of exploring, treat yourself to a delightful dinner or a refreshing drink at the best spots in Arezzo. Choose from a selection of excellent restaurants and bars and find the perfect place for your evening.

Set out on a gastronomic journey in Arezzo by reserving a table at Octavin. Renowned for its , this restaurant presents an outstanding menu of creative cuisine. With its reputation for pleasing customers, it’s a fantastic choice for tonight in Arezzo.

Keep the excitement of the evening going by going to a bar or two. Liquid Bar is an excellent place to start.

Raise your glass and relax after another big day of your luxury holiday in Italy!

Wake up to day 3 of your luxury holiday in Italy! Remember to have a hearty breakfast because today will be filled with memorable adventures in Vatican City. With a flexible itinerary, you're free to adapt and explore additional attractions or enjoy spontaneous discoveries.

Vatican City welcomes you with a multitude of unique vacation experiences.

Begin your sightseeing with a visit to Vatican Museums. This art museum gets 1,612,530 visitors each year and is rated an average of 4.6 out of 5 stars in 133,310 reviews.

Next up, make your way to Sistine Chapel. This chapel has an average rating of 4.7 out of 5 stars from 52,083 reviews.

When you’re ready for your next sight of the day, continue to Saint Peter's Square. This square has an average rating of 4.8 out of 5 stars from 38,954 visitors.

Beyond the above-mentioned attractions, you also have the opportunity to visit St. Peter's Basilica. This major basilica is rated an average of 4.8 out of 5 stars by 131,043 visitors. Visiting St. Peter's Basilica means you'll be one of 11,000,000 people who do so every year.

Relax and unwind in style as you spend the night at one of the top luxury hotels in in Rome.

After exploring the unique sights of Italy, savor a delicious meal or get refreshed with a drink. We’ve gathered the most recommended restaurants and bars in the city of Rome for you so you can browse their menus in advance and make a reservation.

Experience a harmony of flavors at La Pergola in Rome by securing a reservation in advance. Known for its 3-star Michelin status, La Pergola offers a delightful variety of dishes highlighting its delicious mediterranean and contemporary menu. If you're seeking an alternative culinary experience, be sure to explore Il Pagliaccio, a highly recommended restaurant known for its enticing creative and innovative cuisine. This popular 2-star Michelin-awarded venue consistently exceeds expectations, ensuring a memorable holiday experience. Ready for another culinary adventure? Indulge your senses at Enoteca La Torre, a highly acclaimed restaurant celebrated for its exceptional mediterranean and creative menu.

Continue your evening by exploring the vibrant nightlife scene at La Botticella of Poggi Giovanni, a prime destination for a thrilling night out. Also, don’t forget to check out Sant' Eustachio Caffè, a bar that offers unique local touches. Likewise, Caffè Portofino provides an excellent alternative for a fun evening.

Reminisce about your day, look through photos, and prepare for another great day to come! Your stress-free luxury holiday in Italy has plenty more in store for you.

Day 4 of your luxury road trip in Italy begins and concludes in the city of Rome. Set out by car to explore incredible attractions in the nearby area. After a day filled with sightseeing, you'll return to Rome, where you still have 2 nights nights remaining.

Kick off the day at Campo de' Fiori, a top pick for today’s sightseeing. This square is rated an average of 4.4 out of 5 stars in 51,133 reviews.

Today is also your chance to visit Piazza Navona. Piazza Navona is a square with an average rating of 4.7 out of 5 stars from 158,771 reviews.

Pantheon is another top attraction we highly recommend you visit today. This roman temple is rated an average of 4.8 out of 5 stars by 189,682 visitors. In a single year, this roman temple hosts approximately 30,000,000 visitors.

Beyond the attractions mentioned above, you also have the opportunity to visit Roman Forum. This square is rated an average of 4.7 out of 5 stars by 114,450 visitors.

Lastly, don’t miss out on Colosseum, a famous roman amphitheatre in Rome. This attraction welcomes 7,400,000 visitors annually and is rated an average of 4.7 out of 5 stars by 328,821 travelers.

After a full day of exploring, treat yourself to a delightful dinner or a refreshing drink at the best spots in Rome. Choose from a selection of excellent restaurants and bars and find the perfect place for your evening.

After enjoying a delightful dinner, why not delve into the vibrant local bar scene? You might want to spend the evening at The Apartment Bar Roma, a well-loved spot among locals and tourists. Or, head to Hotel Hassler Roma. This bar boasts a welcoming environment that is perfect for winding down.

Reminisce about your day, look through photos, and prepare for another great day to come! Your luxury holiday in Italy has plenty more in store for you.

Day 5 of your luxury road trip in Italy begins and concludes in the city of Rome. Set out by car to explore incredible attractions in the nearby area. After a day filled with sightseeing, you'll return to Rome, where you still have 1 night nights remaining.

Begin your sightseeing with a visit to Spanish Steps. This extraordinary monumental staircase is rated an average of 4.5 out of 5 stars by 57,211 visitors.

Next, make your way to Piazza di Spagna. This top attraction is a square with an average rating of 4.7 out of 5 stars by 113,658 visitors.

We also recommend a visit to Trevi Fountain. This sculpture is rated 4.8 out of 5 stars by 343,494 travelers.

If you’re keen to keep exploring, visit Basilica di Santa Maria Maggiore. This highly recommended sightseeing destination has received an average rating of 4.8 out of 5 stars from 27,678 travelers.

Today is also your chance to spend some time at Circus Maximus. This circus is rated an average of 4.4 out of 5 stars by 44,741 travelers.

Exploring new destinations can leave you craving great food and drinks. Satisfy your cravings and unwind by visiting the finest restaurants and bars in Rome.

With its reputation for pleasing customers, it’s a fantastic choice for tonight in Rome.

Reminisce about your day, look through photos, and prepare for another great day to come! Your stress-free luxury holiday in Italy has plenty more in store for you.

On day 6 of your luxury holiday in Italy, your road trip route will take you exploring the best of Rome. With a day brimming with amazing attractions ahead, fuel up with a hearty breakfast to savor every moment of your luxury vacation in Italy.

When you’re ready for some sightseeing, make your way to Altare della Patria. This much-appreciated architectural structure is rated 4.8 out of 5 stars in 49,843 reviews. Each year, 1,683,070 people visit this site to admire its unique features.

Next up is Castel Sant'Angelo. This museum has an average rating of 4.7 out of 5 stars from 72,431 visitors. As one of the top places to visit in the city, Castel Sant'Angelo welcomes 918,591 visitors annually.

Another top sightseeing recommendation is piazza del Popolo. This square has been rated 4.6 out of 5 stars in 89,807 reviews.

Passeggiata del Pincio is another attraction you have the opportunity to visit today. This park has an average rating of 4.7 out of 5 stars from 11,134 reviews.

To continue your sightseeing, head over to Villa Borghese. This urban zone of rome is rated an average of 4.6 out of 5 stars in 69,749 reviews.

Relax and unwind in style as you spend the night at one of the top luxury hotels in in Province of Salerno.

Exploring new destinations can leave you craving great food and drinks. Satisfy your cravings and unwind by visiting the finest restaurants and bars in Province of Salerno.

Get ready for an unforgettable culinary journey in Province of Salerno by reserving a table at Re Maurì. Renowned as a 1-star Michelin restaurant, it offers an exceptional creative menu.

Continue the enjoyment post-dinner at Hilton Bar e Gastronomia, a cherished local gathering spot renowned for its welcoming atmosphere. Similarly, The Black Monday speakeasy TBM offers a vibrant space for indulging in well-crafted drinks and engaging conversation. You may also want to check out Dòmo i' vinaino Wine Bar - Enogastronomia. This bar is a favorite among both locals and visitors looking for a delightful evening out filled with laughter and fun.

Raise a toast to another amazing day of your luxury holiday in Rome, Italy and seize the opportunity to celebrate.

Wake up to day 7 of your luxury road trip holiday in Italy! Today, you will get the opportunity to visit multiple fantastic bucket-list destinations in the country as you head towards the city of Naples, where you'll be staying for 2 nights. The day's itinerary unfolds with a diverse array of experiences in Amalfi, Ravello, and Pompei.

Set your GPS to Amalfi and hit the road. Expect a journey of approximately 57 min without stops. Soak in the beautiful landscapes as you drive and look forward to exploring your next destination. Amalfi beckons with new experiences!

Seize the day by visiting some of the best attractions in the area, like Amalfi Coast. This extraordinary coast has an average rating of 4.7 out of 5 stars from 70,989 visitors.

As you’ve unraveled the marvels of Amalfi, it’s time to gear up for the next part of your road trip adventure. Under favorable conditions, your drive to Ravello may take around 19 min. Upon your arrival in Ravello, you’ll be greeted with the opportunity to do some sightseeing and exploring.

When you’re ready for some sightseeing, make your way to Villa Rufolo. This much-appreciated sightseeing destination is rated 4.6 out of 5 stars in 16,456 reviews.

Fasten your seatbelt and make your way to your next stop. Pompei, home to many well-known sights in the region, is a lovely destination on today’s itinerary. Keep in mind that your travel time from Ravello to Pompei may take around 47 min without traffic disruptions. Upon arrival in Pompei, we highly recommend checking out some of the top attractions.

Begin your sightseeing with a visit to Archaeological Park of Pompeii. This extraordinary museum is rated an average of 4.7 out of 5 stars by 49,465 visitors.

Next, make your way to Teatro Grande. This top attraction is a point of interest with an average rating of 4.7 out of 5 stars by 5,226 visitors.

We also recommend a visit to Amphitheatre of Pompeii. This sightseeing destination is rated 4.7 out of 5 stars by 14,759 travelers.

Relax and unwind in style as you spend the night at one of the top luxury hotels in in Naples.

Discover a world of culinary delights in Naples, where top-notch dining experiences await at every corner. Consider whether you need to make a reservation in advance to secure a table at your preferred restaurant.

Dive into a culinary adventure like no other in Naples by booking a table at Il Comandante. This popular restaurant holds , and offers an exceptional menu of creative and mediterranean cuisine. For another culinary dining option, venture to ARIA, celebrated for its delectable contemporary and modern menu. This acclaimed 1-star Michelin-recipient consistently leaves guests satisfied, ensuring an essential addition to your holiday itinerary. Seeking an alternative? Discover Veritas, a top local restaurant known for its tantalizing campanian and contemporary menu. With a 1-star Michelin recognition, it promises an exceptional dining experience not to be missed.

Cap off your dinner by heading to Happening cocktail bar, ideal for a leisurely evening with a drink in hand. Shanti Art Musik Bar is another bar that offers an enjoyable setting. Similarly, Gran Caffè Gambrinus is also a popular place to go on a night out, perfect for relaxing and socializing.

Celebrate another great day of your luxury holiday in Italy with a toast! Enjoy a great night’s sleep at your lovely hotel and get ready for another fun day to come.

Day 8 of your luxury road trip in Italy begins and concludes in the city of Naples. Set out by car to explore incredible attractions in the nearby area. After a day filled with sightseeing, you'll return to Naples, where you still have 1 night nights remaining.

A top pick for your self-guided sightseeing tour today is Castel Nuovo. Previous visitors have rated this castle an average of 4.4 out of 5 stars in 28,032 reviews.

Chiesa del Gesù Nuovo is a local recommendation that you also can pay a visit today. This church is rated an average of 4.6 out of 5 stars in 16,437 reviews.

Another attraction you won't want to miss is Cappella Sansevero. This former church is rated an average of 4.7 out of 5 stars in 25,405 reviews. Every year, around 175,138 travelers visit this site to discover its unique features.

Naples National Archaeological Museum is another outstanding experience in Naples. Around 27,352 travelers have rated this archaeological museum an average of 4.6 out of 5 stars. The attraction hosts 616,878 visitors annually.

After exploring the unique sights of Italy, savor a delicious meal or get refreshed with a drink. We’ve gathered the most recommended restaurants and bars in the city of Naples for you so you can browse their menus in advance and make a reservation.

Round off your dining experience by visiting Archivio Storico - Cocktail Bar & Wonderfood, a prime location for a drink. Alternatively, explore the distinctive characteristics of Babette Pub, a bar catering to every mood and preference. Gran Caffè Cimmino likewise offers a unique atmosphere, perfect for a memorable night out.

Raise your glass and relax after another big day of your luxury holiday in Italy!

Wake up to day 9 of your luxury holiday in Italy! Remember to have a hearty breakfast because today will be filled with memorable adventures in Naples and Caserta. With a flexible itinerary, you're free to adapt and explore additional attractions or enjoy spontaneous discoveries.

Take the opportunity to see San Carlo Theatre. This attraction has an average rating of 4.8 out of 5 stars from 7,015 visitors.

Piazza del Plebiscito is another sightseeing hotspot in the area. This square has been rated an average of 4.7 out of 5 stars by 58,141 travelers.

Naples is also the home of Ovo Castle. Around 33,595 people have rated this sightseeing destination an average of 4.6 out of 5 stars.

When you’ve had your share of Naples, prepare for your next destination. Admire the views and listen to some good music as you drive in the direction of Caserta. Your travel time is around 44 min.

Start your sightseeing with a visit to Palace of Caserta. This mountain park is rated an average of 4.6 out of 5 stars from 36,840 visitors. Palace of Caserta welcomes around 296,577 visitors every year.

Giardini Reali - Parco Reggia di Caserta is another popular attraction you could visit today. This sightseeing destination has a rating of 4.7 out of 5 stars from 18,740 visitors.

Relax and unwind in style as you spend the night at one of the top luxury hotels in in L'aquila.

After a long day of discovering the unique quirks of Italy, it’s an excellent idea to sit down for a lovely meal or enjoy a refreshing drink. We’ve gathered the most recommended dining and drinking spots in L'aquila so you can check out the menus and make advance reservations.

Have a memorable dining experience in L'aquila by booking a table at FØRMA contemporary restaurant, renowned as a Bib Gourmand restaurant presenting an exceptional contemporary and creative menu.

After savoring a delicious meal, step into the vibrant nightlife at Art Cafè L'Aquila, where the evening is just getting started.

Reminisce about your day, look through photos, and prepare for another great day to come! Your luxury holiday in Italy has plenty more in store for you.

On day 10 of your luxury holiday in Italy, your road trip route will take you exploring the best of Santa Maria degli Angeli and Perugia. With a day brimming with amazing attractions ahead, fuel up with a hearty breakfast to savor every moment of your luxury vacation in Italy.

When you’ve had your share of L'aquila, prepare for your next destination. Admire the views and listen to some good music as you drive in the direction of Santa Maria degli Angeli. Your travel time is around 2 hours 23 min.

Make Basilica of San Francesco d'Assisi your first stop of the day. Previous visitors have rated this papal basilica an average of 4.9 out of 5 stars in 33,258 reviews.

Continue your road trip and head to your next destination, Santa Maria degli Angeli. This car ride takes around 9 min.

Make Basilica of Santa Maria degli Angeli one of your first sightseeing stops in Santa Maria degli Angeli. Rated an average of 4.8 out of 5 stars by 19,258 travelers, a visit to this local attraction makes for a great introduction to the area.

Perugia’s wonders await as you prepare for another journey on the road, leaving the breathtaking surroundings of Santa Maria degli Angeli behind. This drive usually takes around 20 min. Perugia welcomes you with a multitude of unique vacation experiences.

Kick off the day at Rocca Paolina, a top pick for today’s sightseeing. This rocca is rated an average of 4.7 out of 5 stars in 7,128 reviews.

Today is also your chance to visit Piazza IV Novembre. Piazza IV Novembre is a square with an average rating of 4.6 out of 5 stars from 9,189 reviews.

Relax and unwind in style as you spend the night at one of the top luxury hotels in in Perugia.

Treat yourself after a day of exploration. Make a reservation at the finest dining and drinking spots in Perugia.

As a top-rated it is an ideal choice in the city.

After enjoying a fulfilling meal, continue your evening at Tommi Bar, ideal for those looking to unwind with a drink in a comfortable setting. Alternatively, Valentina offers a welcoming atmosphere for easing into the nightlife. Similarly, Caffe Dal Perugino provides an excellent environment for a relaxed and enjoyable evening.

Raise your glass and relax after another big day of your luxury holiday in Italy!

Wake up to day 11 of your luxury road trip holiday in Italy! Today, you will get the opportunity to visit multiple fantastic bucket-list destinations in the country as you head towards the city of Florence, where you'll be staying for 1 night. The day's itinerary unfolds with a diverse array of experiences in Siena.

Once you're ready to continue your road trip, it's time to buckle up and drive, eagerly anticipating your arrival in Siena. This drive usually takes around 1 hour 23 min, without any stops or traffic disruptions.

Drop by the renowned piazza del Campo. This popular square has been rated an average of 4.8 out of 5 stars by 64,175 visitors.

Another unforgettable place to experience is Pubblico Palace. Rated 4.7 out of 5 stars by 1,400 visitors, this museum deserves a spot on today's sightseeing itinerary.

We also recommend a visit to Siena Cathedral. This domus has been rated an average of 4.8 out of 5 stars in 21,656 reviews.

Another favorite attraction in the area is Fortezza Medicea (Siena). This fortress and popular place of interest enjoys a rating of 4.5 out of 5 stars from 9,835 local and international travelers.

Relax and unwind in style as you spend the night at one of the top luxury hotels in in Florence.

In Florence, delicious dining experiences are never far from reach. Take your pick and consider whether you need to book a table in advance.

Start your culinary exploration in Florence by securing a reservation at Enoteca Pinchiorri. This renowned restaurant holds , and offers an exceptional menu of italian contemporary cuisine. For another dining delight, visit Santa Elisabetta, celebrated for its delectable creative and mediterranean menu. This acclaimed 2-star Michelin-recipient consistently leaves guests satisfied, making it a must-visit during your holiday. Looking for a different experience? Discover Gucci Osteria da Massimo Bottura, a top local spot known for its tantalizing italian contemporary and international menu. With a 1-star Michelin recognition, it guarantees an exceptional dining adventure.

To truly maximize your evening out, consider visiting Manifattura after dinner. This bar is known for offering some of the best drinks and vibes in the city. Alternatively, head to SE·STO on Arno Rooftop Bar, another bar with an inviting ambiance. Similarly, Archea Brewery also offers a great atmosphere, ensuring a night filled with enjoyment and relaxation.

Reminisce about your day, look through photos, and prepare for another great day to come! Your stress-free luxury holiday in Italy has plenty more in store for you.

Wake up to day 12 of your luxury holiday in Italy! Remember to have a hearty breakfast because today will be filled with memorable adventures in Florence. With a flexible itinerary, you're free to adapt and explore additional attractions or enjoy spontaneous discoveries.

Make piazza della Signoria one of your first sightseeing stops in Florence. Rated an average of 4.8 out of 5 stars by 66,956 travelers, a visit to this local attraction makes for a great introduction to the area.

Cathedral of Santa Maria del Fiore is a worthwhile attraction you can visit next. This church is a valued place of interest in the area, with an average rating of 4.8 out of 5 stars from 76,359 reviews.

Today is also the perfect opportunity to drop by Ponte Vecchio. This deck arch bridge has been rated an average of 4.7 out of 5 stars by 118,099 visitors.

If you’re keen to explore more, head to Uffizi Gallery and find out why 2,011,219 people visit this spot every year. A trip to this popular national museum is also your opportunity to see if it lives up to the reputable 4.7 out of 5-star rating as given by 61,794 previous visitors.

Another top place to visit is piazzale Michelangelo. This square enjoys an average rating of 4.8 out of 5 stars from 77,744 local and international travelers.

Relax and unwind in style as you spend the night at one of the top luxury hotels in in Pisa.

After a long day of exploring, it’s a great idea to relax with a lovely dinner or a refreshing drink. We’ve gathered the most recommended dining and drinking spots in Pisa for you, so you can check out the menus and make your reservation in advance.

Continue your lively evening at Bar Mocambo, a perfect place for winding down or revving up the night, depending on which mood you’re in. Tree is another excellent bar that offers a great selection of drinks to suit any mood. If you prefer to go somewhere else, Chupiteria ensures a night out tailored to your taste.

Raise a toast to another amazing day of your luxury holiday in Florence, Italy and seize the opportunity to celebrate.

Today is the last day of your 13-day luxury holiday in Italy and it’s soon time to start your journey home. This is your chance to get one last glimpse of Pisa before saying goodbye.

Make the most of your final day in Italy by visiting Pisa’s iconic markets and shopping establishments. Your stay’s proximity to the city’s retail haven invites an unhurried and unforgettable exploration of its variety of stores and establishments. Secure the perfect souvenirs for your family and friends back home or buy yourself a remembrance of your amazing experience in Italy. Take home a piece of Italy with these souvenirs, keeping your adventures close.

Make the most of what's left of your luxury vacation and head out to the stunning Palazzo Gambacorti. This extraordinary palace and attraction is rated an average of 4.3 out of 5 stars in 309 reviews, and is an excellent choice for your last sightseeing in Pisa.

Treat yourself to a final feast. Savor the unique flavors of Pisa one last time before you head to the airport.

If you're in the mood to try something new, consider Kiste' - La Pizza Artigianale. It's the second restaurant coming from the tower. , another top spot with a mouthwatering menu.

You will then say farewell to Pisa and begin your journey home. We wish you safe travels and a warm welcome home, with unforgettable memories and incredible photos from your luxury holiday in Italy in your luggage!