Luxury 6-Day Italy Road Trip from Perugia to Rome and Siena

Your luxury holiday in Italy begins as soon as you reach the city of Perugia, where you'll be staying for 1 night. There, you’ll pick up the luxury rental vehicle of your choice and hit the roads!

Journey into the unknown at Piazza IV Novembre, a unique attraction awaiting your visit. This remarkable square has an average rating of 4.6 out of 5 stars from 9,189 reviews.

Tonight, you will be treated to a stay at one of the best luxury hotels in Perugia. We have picked out three of the most exclusive luxury lodging and hotel options for you to choose from.

Treat yourself after a day of exploration. Make a reservation at the finest dining and drinking spots in Perugia.

After your meal, keep the night alive at a bar like Tommi Bar, known for its lively atmosphere. Valentina is another top recommendation that provides the perfect setting with well-crafted drinks and a welcoming ambiance. Similarly, Caffe Dal Perugino offers an excellent atmosphere for those looking to amp up the evening.

Raise a toast to the start of your 6-day luxury vacation in Italy and look forward to more fantastic days to come!

On day 2 of your luxury holiday in Italy, your road trip route will take you exploring the best of Perugia. With a day brimming with amazing attractions ahead, fuel up with a hearty breakfast to savor every moment of your luxury vacation in Italy.

When you’ve had your share of Perugia, prepare for your next destination. Admire the views and listen to some good music as you drive in the direction of Rome. Your travel time is around 2 hours 18 min.

Drop by the renowned Carducci Gardens. This popular park has been rated an average of 4.5 out of 5 stars by 1,768 visitors.

Another unforgettable place to experience is Porta Marzia. Rated 4.6 out of 5 stars by 119 visitors, this city gate deserves a spot on today's sightseeing itinerary.

We also recommend a visit to Rocca Paolina. This rocca has been rated an average of 4.7 out of 5 stars in 7,128 reviews.

Another favorite attraction in the area is National Archaeological Museum of Umbria. This museum and popular place of interest enjoys a rating of 4.5 out of 5 stars from 669 local and international travelers.

If you’re keen to explore even more, then consider a visit to Convent of San Domenico. With an average rating of 4.5 out of 5 stars from 590 travelers, this church is an attraction many avid travelers highly recommend visiting while in Perugia.

Relax and unwind in style as you spend the night at one of the top luxury hotels in in Rome.

After a long day of exploring, it’s a great idea to relax with a lovely dinner or a refreshing drink. We’ve gathered the most recommended dining and drinking spots in Rome for you, so you can check out the menus and make your reservation in advance.

Treat yourself to an extraordinary dining experience at La Pergola, a 3-star Michelin restaurant offering an incredible mediterranean and contemporary menu. Alternatively, if your taste buds call for something different, Il Pagliaccio is one of the best restaurants for creative and innovative cuisine in Rome. This 2-star Michelin-awardee earns consistently high praises from guests. We also recommend checking out the menu at Enoteca La Torre. As a top-rated it is an ideal choice for mediterranean and creative cuisine in the city.

After enjoying a delightful dinner, why not delve into the vibrant local bar scene? You might want to spend the evening at La Botticella of Poggi Giovanni, a well-loved spot among locals and tourists. Or, head to Sant' Eustachio Caffè. This bar boasts a welcoming environment that is perfect for winding down. You could also continue your night at Caffè Portofino, another top-rated place in the area.

Reminisce about your day, look through photos, and prepare for another great day to come! Your stress-free luxury holiday in Italy has plenty more in store for you.

Day 3 of your luxury road trip in Italy begins and concludes in the city of Rome. Set out by car to explore incredible attractions in the nearby area. After a day filled with sightseeing, you'll return to Rome, where you still have 1 night nights remaining.

Drop by the renowned Castel Sant'Angelo. This popular museum has been rated an average of 4.7 out of 5 stars by 72,431 visitors. Based on recent data, this attraction is visited by more than 918,591 travelers every year.

Another unforgettable place to experience is piazza del Popolo. Rated 4.6 out of 5 stars by 89,807 visitors, this square deserves a spot on today's sightseeing itinerary.

We also recommend a visit to Piazza di Spagna. This square has been rated an average of 4.7 out of 5 stars in 113,658 reviews.

Another favorite attraction in the area is Colosseum, drawing over 7,400,000 yearly visitors. This roman amphitheatre and popular place of interest enjoys a rating of 4.7 out of 5 stars from 328,821 local and international travelers.

If you’re keen to explore even more, then consider a visit to Roman Forum. With an average rating of 4.7 out of 5 stars from 114,450 travelers, this square is an attraction many avid travelers highly recommend visiting while in Rome.

After exploring the unique sights of Italy, savor a delicious meal or get refreshed with a drink. We’ve gathered the most recommended restaurants and bars in the city of Rome for you so you can browse their menus in advance and make a reservation.

If you’re not ready to end the night just yet, The Apartment Bar Roma offers a perfect venue to relax and savor a drink. Similarly, Hotel Hassler Roma is well-suited for those looking to unwind in a social setting.

Reminisce about your day, look through photos, and prepare for another great day to come! Your stress-free luxury holiday in Italy has plenty more in store for you.

Wake up to day 4 of your luxury road trip holiday in Italy! Today, you will get the opportunity to visit multiple fantastic bucket-list destinations in the country as you head towards the city of Siena, where you'll be staying for 1 night. The day's itinerary unfolds with a diverse array of experiences in Rome and Vatican City.

Begin your sightseeing with a visit to Altare della Patria. This extraordinary architectural structure is rated an average of 4.8 out of 5 stars by 49,843 visitors. Each year, around 1,683,070 people visit this site to learn more about it.

Next, make your way to Trevi Fountain. This top attraction is a sculpture with an average rating of 4.8 out of 5 stars by 343,494 visitors.

We also recommend a visit to Pantheon. Hosting 30,000,000 visitors every year, Pantheon is one of the most popular places to visit in Rome. This roman temple is rated 4.8 out of 5 stars by 189,682 travelers.

If you’re keen to keep exploring, visit Piazza Navona. This highly recommended sightseeing destination has received an average rating of 4.7 out of 5 stars from 158,771 travelers.

Upon your arrival in Vatican City, you’ll be greeted with the opportunity to do some sightseeing and exploring.

Seize the day by visiting some of the best attractions in the area, like St. Peter's Basilica. This extraordinary major basilica has an average rating of 4.8 out of 5 stars from 131,043 visitors. Each year, around 11,000,000 people visit this remarkable site to admire its features and learn more about it.

Relax and unwind in style as you spend the night at one of the top luxury hotels in in Siena.

In Siena, delicious dining experiences are never far from reach. Take your pick and consider whether you need to book a table in advance.

Continue the enjoyment post-dinner at Meet Life Cafè, a cherished local gathering spot renowned for its welcoming atmosphere. Similarly, Maudit Pub offers a vibrant space for indulging in well-crafted drinks and engaging conversation. You may also want to check out Bar Impero Siena. This bar is a favorite among both locals and visitors looking for a delightful evening out filled with laughter and fun.

Raise your glass and relax after another big day of your luxury holiday in Italy!

Wake up to day 5 of your luxury holiday in Italy! Remember to have a hearty breakfast because today will be filled with memorable adventures in Santa Maria degli Angeli and Siena. With a flexible itinerary, you're free to adapt and explore additional attractions or enjoy spontaneous discoveries.

Set your GPS to Santa Maria degli Angeli and hit the road. Expect a journey of approximately 1 hour 38 min without stops. Soak in the beautiful landscapes as you drive and look forward to exploring your next destination. Santa Maria degli Angeli beckons with new experiences!

Take the opportunity to see Basilica of San Francesco d'Assisi. This attraction has an average rating of 4.9 out of 5 stars from 33,258 visitors.

Santa Maria degli Angeli’s wonders await as you prepare for another journey on the road, leaving the breathtaking surroundings of Siena behind. This drive usually takes around 1 hour 38 min. Santa Maria degli Angeli welcomes you with a multitude of unique vacation experiences.

Make piazza del Campo one of your first sightseeing stops in Siena. Rated an average of 4.8 out of 5 stars by 64,175 travelers, a visit to this local attraction makes for a great introduction to the area.

Siena Cathedral is a worthwhile attraction you can visit next. This domus is a valued place of interest in the area, with an average rating of 4.8 out of 5 stars from 21,656 reviews.

After soaking in Santa Maria degli Angeli’s unique atmosphere, jump into the car with a full heart and drive in the direction of your next destination: Santa Maria degli Angeli. Expect your car journey to take a minimum of 9 min. When you arrive in Santa Maria degli Angeli, it's time to take a break from the road.

Start your sightseeing with a visit to Basilica of Santa Maria degli Angeli. This papal basilica is rated an average of 4.8 out of 5 stars from 19,258 visitors.

Relax and unwind in style as you spend the night at one of the top luxury hotels in in Perugia.

Exploring new destinations can leave you craving great food and drinks. Satisfy your cravings and unwind by visiting the finest restaurants and bars in Perugia.

Let the evening flow smoothly from dinner to drinks at Caffè Fortebraccio, a top-rated bar in the area. For other recommendations, Caffe Del Banco provides a perfect setting for rounding out your night with style and great drinks. Likewise, Dempsey's Perugia offers a memorable night with diverse drink options and excellent service.

Raise a toast to another amazing day of your luxury holiday in Santa Maria degli Angeli, Italy and seize the opportunity to celebrate.

Today is the last day of your 6-day luxury holiday in Italy and it’s soon time to start your journey home. This is your chance to get one last glimpse of Perugia before saying goodbye.

As you approach the end of your journey in Italy, take a moment for some retail therapy in Perugia’s celebrated shopping district. Thanks to your stay’s premier location, you can easily visit the city’s commercial hubs and wander through its diverse range of local shops without rushing.

Whether you’re on a hunt for an ideal present to give to your friends or family or looking for a personal memento to remind you of Italy, a variety of items are waiting for you. Hold onto the magic of Italy with these wonderful souvenirs, ensuring your memories never fade.

Treat yourself to a final feast. Savor the unique flavors of Perugia one last time before you head to the airport.

This renowned restaurant holds , and offers an exceptional menu of cuisine.

You will then say farewell to Perugia and begin your journey home. We wish you safe travels and a warm welcome home, with unforgettable memories and incredible photos from your luxury holiday in Italy in your luggage!