9-Day Italy Self-Drive Road Trip With Itinerary from Genoa traveling east to Pisa, Viterbo, Rome, and Florence

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Explore the best of Italy on a 9-day road trip! Uncover hidden gems and experience the rich culture firsthand as you journey through Genoa, Pisa, Viterbo, Rome, Florence, and Siena. This road trip itinerary in Italy seamlessly combines exploration with relaxation.

This perfectly planned road trip itinerary in Italy takes you through some of the best places to see in the country. You will spend 2 nights in Genoa, 1 night in Pisa, 1 night in Viterbo, 2 nights in Rome, and 2 nights in Florence. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Italy. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have got you covered.

Upon arriving in Genoa, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Italy on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Italy. Trevi Fountain and Colosseum are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Pantheon, learn more about the unique Piazza Navona, and immerse yourself in the vibrant atmosphere of St. Peter's Basilica.

As you hit the open road and drive through Genoa, Pisa, Viterbo, Rome, Florence, and Siena, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Italy. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Italy.

Throughout your road trip in Italy, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Italy.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodation, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Italy fill up quickly, so book your spot early. Select a date and start planning your road trip in Italy today!

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Itinerary summary

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Days
Destination
Attractions
Overnight
Day
City & Overnight
Attractions
porto antico
piazza De FerrariDoge's PalaceGenoa CathedralAquarium of Genoa
Knights' SquareLeaning Tower of PisaPiazza del Duomo, PisaPisa Cathedral
Vatican MuseumsSistine ChapelSaint Peter's SquareSt Peter's Basilica
ColosseumRoman ForumPantheonPiazza NavonaCastel Sant'Angelo
Altare della PatriaTrevi FountainPiazza di Spagnapiazza del PopoloVilla Borghese

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Day 1

Day 1

  • Genoa - Arrival day
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  • porto antico
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Say hello to Genoa! Your exciting road trip through Italy is just about to start. Navigating the top places to see in the region is a breeze with a car. The rental vehicle of your choice will be ready for pickup upon your arrival in the city. You will stay in Genoa for 1 night before you continue your adventure!

Genoa is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Porto Antico, or just taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

Make your way to your chosen hotel. Check-in typically starts between 2 and 4 PM in Genoa. Make yourself at home and enjoy some downtime before heading out again.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Genoa, it's often a good idea to reserve a table in advance.

Treat yourself to a wonderful meal at 7 Sensi cucina decontaminata, a top-rated dining spot in Genoa. If you're in the mood for something new, try Alla Lunga Ristorante, another premier location with a delectable menu. You might also want to book a table at Grand Hotel Savoia. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Genoa.

To truly maximize your evening out, consider visiting Scurreria Beer & Bagel after dinner. This bar is known for offering some of the best drinks and vibes in the city. Alternatively, head to La Lepre, another bar with an inviting ambiance. Similarly, Bar Pisacane Iii also offers a great atmosphere, ensuring a night filled with enjoyment and relaxation.

Raise a toast to the start of your 9-day road trip in Italy!

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Day 2

Day 2

  • Genoa
  • Pisa
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Drive 176 km, 2 hours 17 min

  • piazza De Ferrari
  • Doge's Palace
  • Genoa Cathedral
  • Aquarium of Genoa
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Dive into day 2 of your remarkable road trip in Italy. Today you will explore Genoa, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Pisa. You’ll stay here for 1 night.

Today’s well-planned self-sightseeing route offers several fun adventures, romantic experiences, and breathtaking views. Whether you decide to explore Genoa on foot, use public transport, or join a guided tour, there are a few attractions you don’t want to miss. Piazza De Ferrari is the first of them. Spend some time admiring this visually striking public square before continuing your journey. Doge's Palace is your next stop. This worthwhile museum is one of the best-rated sights in Genoa.

Consider grabbing some lunch or a light snack to keep your energy going. Beyond the above-mentioned attractions, today is also the perfect time to visit Genoa Cathedral. This standout church is a sight to behold. To round off your sightseeing experience, visit Aquarium Of Genoa.

At the end of the day, you will drive to Pisa, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Pisa. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Have a fantastic dining experience at Anima di Grano Pizzeria Napoletana Pisa Italy, a highly recommended choice for tonight's dinner. If you're looking to mix things up, il Mercante offers an enticing alternative with its varied menu. Additionally, La Ghiotteria is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Pisa.

To truly maximize your evening out, consider visiting Jeffer Cocktails & Friends after dinner. This bar is known for offering some of the best drinks and vibes in the city. Alternatively, head to Le Parisien Wine Bar, another bar with an inviting ambiance. Similarly, Las Volta Cocktailbar also offers a great atmosphere, ensuring a night filled with enjoyment and relaxation.

As the sun sets on another day of adventure, rest up and recharge for the next leg of your road trip in Italy.

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Day 3

Day 3

  • Pisa
  • Viterbo
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Drive 282 km, 3 hours 36 min

  • Knights' Square
  • Leaning Tower of Pisa
  • Piazza del Duomo, Pisa
  • Pisa Cathedral
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Embark on another extraordinary experience on day 3 of your road trip in Italy. Today, you will make 1 stop and experience some of the highlights of Pisa. At the end of the day, you will enjoy the comforts of a top-rated hotel in Viterbo, which will be your home away from home for 1 night.

Pisa is brimming with adventures. Today’s wonderful stops include a public square, a monument, and a church. Begin your sightseeing adventure at the intriguing Knights' Square. Just a short distance away is Leaning Tower Of Pisa, a breathtaking monument that draws visitors from far and near.

Continue your journey to Piazza Del Duomo, Pisa, one of the city’s most timeless spots that you shouldn’t miss. Another great site to visit is the increasingly popular Pisa Cathedral.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Viterbo. Viterbo offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

Indulge in a memorable dining experience at one of Viterbo's most popular restaurants, and connect with friendly locals for an authentic adventure.

Head back to your accommodation in Viterbo and get some rest in preparation for another magical day of your road trip in Italy!

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Day 4

Day 4

  • Viterbo
  • Rome
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Drive 117 km, 1 hour 46 min

  • Vatican Museums
  • Sistine Chapel
  • Saint Peter's Square
  • St Peter's Basilica
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On day 4 of your road trip in Italy, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Vatican City. In the evening, you’ll end up in Rome, where you will stay for 2 nights.

Vatican Museums is must-visit art museum and a great starting point for the day. Next, continue your journey to Sistine Chapel, an extraordinary chapel, located just a leisurely stroll away.

Each stop on today’s itinerary promises to leave you with lasting memories and a deeper appreciation for Viterbo. If you’re looking for more, St. Peter's Basilica is also a globally renowned attraction that is worthwhile a visit.

When you’re done exploring for the day, you’ll drive to your hotel in Rome. Check in and spend some time relaxing before you head out to tour the city.

As dinnertime approaches, it's time to head out for a bite to eat in Rome. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Begin your culinary exploration in Rome by securing a reservation at La Pergola. This renowned restaurant holds 3 Michelin star and offers an exceptional menu of mediterranean and contemporary cuisine. For another dining delight, visit Il Pagliaccio, celebrated for its delectable creative and innovative menu. This acclaimed 2-star Michelin-recipient consistently leaves guests satisfied, making it a must-visit during your holiday. Looking for a different experience? Discover Enoteca La Torre, a top local spot known for its tantalizing mediterranean and creative menu. With a 2-star Michelin recognition, it guarantees an exceptional dining adventure.

Unwind after your meal by stepping into La Botticella Of Poggi Giovanni. This venue is celebrated for its extensive drink selections and cozy vibes. Alternatively, Almalu Trastevere offers a dynamic and energetic atmosphere for a glass or two. Don’t overlook Bar Viminale Di Pepi Maurilio, another top-rated bar in the area.

Raise your glass and celebrate another amazing day of your road trip in Italy!

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Day 5

Day 5

  • Rome
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Drive 9 km, 1 hour 11 min

  • Colosseum
  • Roman Forum
  • Pantheon
  • Piazza Navona
  • Castel Sant'Angelo
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Day 5 offers a multitude of experiences. You will stay in Rome for 1 night more, offering you enough time to explore at a relaxed pace.

Today's adventure in Rome promises more breathtaking discoveries and enriching experiences! Begin at Colosseum. This picture-perfect archeological site is a highlight of any visit in the city. Then, enjoy Roman Forum, another breathtaking attraction that never fails to captivate visitors. Next, head over to Pantheon, one of the city’s most iconic attractions, known for its inviting features.

If you’re looking for more, spend time soaking in the atmosphere of Piazza Navona. This visually striking public square is frequented by locals and tourists alike. To complete your memorable day, make sure to visit Castel Sant'angelo, a famous castle, and take a stroll around the area.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

After a day of adventure, treat yourself to an exquisite dinner at one of Rome's best restaurants.

Dine in style at RomAntica, a top recommendation for dinner tonight. Or, for a change of pace, Coso Ristorante boasts a menu that's sure to impress. Also, be sure to check out DEROMA - Farine Romane. Known as a local hotspot, it’s a great choice for tonight in Rome.

Cap off your culinary experience with a visit to some of the most celebrated bars in the area. For instance, Sant' Eustachio Caffè stands out as an excellent choice for a post-dinner cocktail. Alternatively, Yellowsquare Rome offers an ideal atmosphere to enjoy the pleasures of the night. Caffè Portofino is also a great option that provides a perfect setting for a relaxing evening.

Raise your glass to another unforgettable day in Italy!

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Day 6

Day 6

  • Rome
  • Florence
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Drive 280 km, 3 hours 54 min

  • Altare della Patria
  • Trevi Fountain
  • Piazza di Spagna
  • piazza del Popolo
  • Villa Borghese
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Experience an unparalleled adventure on day 6 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 1 vibrant destinations - Rome. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Florence. You will spend 2 nights here for some well-deserved relaxation.

Savor the day by visiting some of the best places to see in Rome, including a monument, a public square, and a park. Start your adventure at Altare Della Patria. This popular monument is a must-visit for travelers looking for a unique holiday experience. Make your way to Trevi Fountain located in Rome for an enchanting atmosphere.

Next, immerse yourself in the setting of Piazza Di Spagna. Its romantic features will captivate you. After the public square, continue your tour of the city with a visit to Piazza Del Popolo. This public square has a romantic appeal. For a change of pace, head to Villa Borghese. As one of the most impressive attractions in Rome, this park is an excellent place to end your self-guided tour.

At the end of the day, you will drive to Florence, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Florence. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Have a memorable dining experience in Florence by booking a table at Enoteca Pinchiorri, renowned as a 3-star Michelin restaurant presenting an exceptional italian contemporary menu. For a different culinary experience in Florence, Santa Elisabetta shines as one of the top destinations, known for its delicious creative and mediterranean cuisine. This 2-star Michelin-awardee earns consistently high praises from previous guests, making it a must-visit addition to your holiday experience. If you're looking for an alternative, Gucci Osteria da Massimo Bottura is known as a top local spot for its delicious italian contemporary and international cuisine in Florence. This 1-star Michelin awardee is a highly recommended choice for an unforgettable meal.

Keep the evening going at Manifattura, a great choice for enjoying the after-dinner hours with a drink. You could also go to Se·sto On Arno Rooftop Bar, which offers a similarly pleasant setting and great drinks. Another option is Il Vinile, which provides an inviting environment for unwinding after a busy day out.

Say good night to Florence and look forward to another great day of your road trip in Italy!

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Day 7

Day 7

  • Florence
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Drive 160 km, 2 hours 56 min

  • piazza del Campo
  • Siena Cathedral
  • piazzale Michelangelo
  • Galleria dell'Accademia
  • Central Market
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At the end of the day, you'll drive back to Florence, where you'll stay for 1 night more.

Today’s well-planned self-sightseeing route offers several fun adventures, romantic experiences, and breathtaking views. Whether you decide to explore Florence on foot, use public transport, or join a guided tour, there are a few attractions you don’t want to miss. Piazza Del Campo is the first of them. Spend some time admiring this romantic public square before continuing your journey. Siena Cathedral is your next stop. This interesting church is one of the best-rated sights in Florence.

Consider grabbing some lunch or a light snack to keep your energy going. Beyond the above-mentioned attractions, today is also the perfect time to visit Piazzale Michelangelo. This history-steeped observation deck is a sight to behold. To round off your sightseeing experience, visit Galleria Dell'accademia and Central Market.

When you’re done exploring for the day, you’ll return to Florence and your accommodation.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Florence. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Treat yourself to a delicious dinner at Ditta Artigianale, an excellent option for tonight's dining. Looking for something different? Trattoria Da Burde offers a tantalizing alternative with its diverse menu. And don’t miss Casa Toscana. With its reputation for pleasing customers, it’s a fantastic choice for tonight in Florence.

Keep the excitement of the evening going by visiting a bar or two. Bar 50 Rosso is an excellent place to start. You could also check out Bitter Bar, offering a different kind of charm. A last recommendation for the day is Archea Brewery. This bar promises an enjoyable experience with tasty drinks and a vibrant setting.

Get a good night's sleep and look forward to another great day on the road in Italy!

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Day 8

Day 8

  • Florence
  • Genoa
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Drive 235 km, 3 hours 7 min

  • piazza della Signoria
  • Uffizi Gallery
  • Ponte Vecchio
  • Cathedral of Santa Maria del Fiore
  • Giotto's Bell Tower
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On day 8 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 1 destination, Florence. When you’re not sightseeing, take time to relax at your selected hotel in Genoa, where you’ll be staying for 1 night.

Florence is home to plenty of attractions that offer family-friendly attractions, romantic experiences, and breathtaking views! Start at Piazza Della Signoria, an extraordinary public square that is worthwhile a visit in the city. Nearby, you’ll find Uffizi Gallery, enchanting visitors with its history-steeped appeal. Continue your exploration at Ponte Vecchio. This historical landmark is one of the city’s most globally renowned spots.

Enjoy the freedom of exploring Florence at your own pace and find hidden gems along the way. If you want to see more picture-perfect spots, make sure to visit Cathedral Of Santa Maria Del Fiore. After exploring the church, head to the up-and-coming Giotto's Bell Tower. This monument will wrap up today’s self-guided sightseeing tour in the city.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Genoa. Genoa offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

As you explore more of Genoa, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Get ready for an unforgettable culinary journey in Genoa by reserving a table at San Giorgio. Renowned as a 1-star Michelin restaurant, it offers an exceptional modern and ligurian menu. For a different taste experience, head to The Cook, recognized for its delicious modern dishes. This 1-star Michelin restaurant consistently impresses guests, ensuring a memorable addition to your holiday. Looking for another option? Make sure to visit Il Marin, a local favorite known for its delightful seafood and contemporary cuisine in Genoa. Nestled in the heart of the city, this restaurant with 1 Michelin star is an ideal choice for discerning seafood and contemporary foodies seeking culinary excellence.

Take some time to reflect on your day and savor another beautiful night in Italy.

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Day 9

Day 9

  • Genoa - Departure day
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  • Via Garibaldi
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Day 9 of your road trip in Italy is your departure day. This is your chance to catch a last glimpse of Genoa before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, begin at Via Garibaldi. This up-and-coming street is a popular place to see in the city.

Explore local shops for souvenirs to remember your trip or find unique gifts for loved ones.

Before you conclude your road trip in Italy, drop by another restaurant for a last chance at a memorable dining experience in Genoa.

You’ll then say farewell to Genoa. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Italy!

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