9-Day Italy Self-Drive Road Trip With Itinerary from Perugia to Rome, Siena, and Florence and surrounding area
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Experience the freedom of the open road in Italy as you embark on an unforgettable 9-day road trip! This experience caters to every traveler, featuring destinations like Perugia, Rome, Siena, Pisa, Florence, and Santa Maria degli Angeli.
This perfectly planned road trip itinerary in Italy takes you through some of the best places to see in the country. You will spend 2 nights in Perugia, 3 nights in Rome, 1 night in Siena, and 2 nights in Florence. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!
With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Italy. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have got you covered.
Upon arriving in Perugia, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Italy on your own terms.
An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Italy. Trevi Fountain and Colosseum are just a couple of the bucket-list attractions that await your discovery.
As you hit the open road and drive through Perugia, Rome, Siena, Pisa, Florence, and Santa Maria degli Angeli, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Italy. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Italy.
Throughout your road trip in Italy, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Italy.
This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodation, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.
The best services in Italy fill up quickly, so book your spot early. Select a date and start planning your road trip in Italy today!
Itinerary summary
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Day 1 – Perugia - arrival day
- Perugia - Arrival day
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- Etruscan Arch
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Your road trip adventure in Italy begins as soon as you reach Perugia and pick up your car. You’ll stay in Perugia for 1 night and explore the best things to see and do, sample the local cuisine, and choose from a curated selection of the best hotels and places to stay in the city.
Perugia is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Etruscan Arch or taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.
Find your way to your hotel in Perugia. We recommend choosing a hotel in a central location for easy exploring. Check-in typically starts between 2 and 4 PM at hotels in Italy. Settle in and make plans for the evening.
As dinnertime approaches, it's time to head out for a bite to eat in Perugia. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.
Make sure to book a table at Ristorante Settimo Sigillo, a popular restaurant in Perugia. This acclaimed restaurant and its mouthwatering dishes have earned the admiration of countless food lovers. Alternatively, experience a taste of Perugia at Caffè Baglioni, a popular local restaurant. With a menu designed to impress, it promises a journey of flavors that will leave you captivated. Another top-rated restaurant to try is Bar Pellas. As a dining spot that gains high praise from guests, it’s an ideal choice to enhance your time to Perugia tonight.
Cap off your dinner by heading to Tommi Bar, ideal for a leisurely evening with a drink in hand. Valentina is another bar that offers an enjoyable setting. Similarly, Caffe Dal Perugino is also a popular place to go on a night out, perfect for relaxing and socializing.
Raise a toast to the start of your 9-day road trip in Italy!
Day 2 – Perugia and Rome
- Perugia
- Rome
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Drive 183 km, 2 hours 27 min
- The Fontana Maggiore
- Piazza IV Novembre
- National Gallery
- Chiesa del Gesù
- Etruscan Arch
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Experience an unparalleled adventure on day 2 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 1 vibrant destinations - Perugia. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Rome. You will spend 3 nights here for some well-deserved relaxation.
Immerse yourself in Perugia’s rich culture with today's sightseeing itinerary. Start your journey at The Fontana Maggiore. This breathtaking monument is sure to ignite your curiosity. Next, dive into the visually striking features of Piazza Iv Novembre, a must-visit public square in the city.
In between sights, stop by local stores, picturesque photo spots, and small eateries. When you’re ready for your next attraction, proceed to National Gallery, a locally appreciated art gallery. For a change of scene, check out Chiesa Del Gesù, known for its photogenic features.
At the end of the day, you will drive to Rome, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.
As you explore more of Rome, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.
Get ready for an unforgettable culinary journey in Rome by reserving a table at La Pergola. Renowned as a 3-star Michelin restaurant, it offers an exceptional mediterranean and contemporary menu. For a different taste experience, head to Il Pagliaccio, recognized for its delicious creative and innovative dishes. This 2-star Michelin restaurant consistently impresses guests, ensuring a memorable addition to your holiday. Looking for another option? Make sure to visit Enoteca La Torre, a local favorite known for its delightful mediterranean and creative cuisine in Rome. Nestled in the heart of the city, this restaurant with 2 Michelin star is an ideal choice for discerning mediterranean and creative foodies seeking culinary excellence.
Cap off your dinner by heading to La Botticella Of Poggi Giovanni, ideal for a leisurely evening with a drink in hand. Almalu Trastevere is another bar that offers an enjoyable setting. Similarly, Bar Viminale Di Pepi Maurilio is also a popular place to go on a night out, perfect for relaxing and socializing.
Raise your glass and celebrate another amazing day of your road trip in Italy!
Day 3 – Rome
- Rome
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Drive 14 km, 1 hour 12 min
- Villa Borghese
- Trevi Fountain
- Piazza di Spagna
- Spanish Steps
- piazza del Popolo
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On day 3 of your road trip, you will have an entire day to explore Rome. You’ll stay in Rome for 2 nights and discover all the best things to see and do in the area.
Enjoy the perfect balance of relaxation and exploration in Rome today. One of the most top-rated attractions included on the itinerary is Villa Borghese. This mesmerizing park will help you start your sightseeing on top. Then, take a leisurely stroll to Trevi Fountain and learn what makes this enchanting monument unique.
Throughout the day, make sure to take breaks to appreciate the surroundings. Next up, visit the world-famous Piazza Di Spagna. After exploring the public square, head to Spanish Steps. This famous public square is a highlight in Rome. Lastly, don’t forget to check out the spectacular Piazza Del Popolo. Enjoy exploring this incredible public square at your own pace.
Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.
As dinnertime approaches, it's time to head out for a bite to eat in Rome. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.
Enjoy a delicious meal at RomAntica, a highly-rated dining destination in Rome. If you're eager to try something different, consider Coso Ristorante, another top spot with a tantalizing menu. You might also want to secure a reservation at DEROMA - Farine Romane. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Rome this evening.
To truly maximize your evening out, consider visiting Sant' Eustachio Caffè after dinner. This bar is known for offering some of the best drinks and vibes in the city. Alternatively, head to Yellowsquare Rome, another bar with an inviting ambiance. Similarly, Caffè Portofino also offers a great atmosphere, ensuring a night filled with enjoyment and relaxation.
Take some time to reflect on your day and savor another beautiful night in Italy.
Day 4 – Rome
- Rome
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Drive 7 km, 1 hour 17 min
- Piazza Navona
- Castel Sant'Angelo
- Altare della Patria
- Roman Forum
- Colosseum
- Trevi Fountain
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Day 4 of your road trip across Italy promises a magnificent time exploring Rome. You have 1 night left in Rome. Take the opportunity to experience more of the best attractions and activities in the city.
Whether you prefer a leisurely exploration or a more fast-paced adventure, this itinerary in Rome allows for both. Start by heading to Piazza Navona. This iconic public square provides an insightful glimpse into the city's identity. Next, discover Castel Sant'angelo, a visually striking castle, promising a delightful encounter.
Continue your sightseeing with a visit to Altare Della Patria, a notable monument. When you’re done, don’t forget to make a stop at the globally renowned Roman Forum. Round off your day at Colosseum, another gem in Rome with historic features to discover.
Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.
After a day of adventure, treat yourself to an exquisite dinner at one of Rome's best restaurants.
Savor the flavors at Hotel de Russie, a top pick for dinner tonight. Alternatively, La Taverna Italiana beckons with its unique menu offerings. Also, consider The Parrot Bar. With its consistent customer satisfaction, it’s an excellent option for dining in Rome tonight.
Extend your evening after a delightful meal by visiting The Apartment Bar Roma, which offers the perfect atmosphere for a night out. Moreover, Hotel Hassler Roma is another popular option for a drink or two.
Say good night to Rome and look forward to another great day of your road trip in Italy!
Day 5 – Rome, Vatican City, and Siena
- Rome
- Siena
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Drive 243 km, 3 hours 26 min
- Pantheon
- St Peter's Basilica
- Sistine Chapel
- Vatican Museums
- Trevi Fountain
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Dive into day 5 of your remarkable road trip in Italy. Today you will explore Rome and Vatican City, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Siena. You’ll stay here for 1 night.
Start your adventure at Pantheon. This globally renowned monument is a place that is appreciated by travelers and locals alike.
When you’re ready to jump back into the car and say goodbye to Rome, you’ll hit the road in the direction of Vatican City, Vatican City. Witness the landscapes transform as you cross the border to Vatican City. This drive usually takes around 11 min. When you arrive, enjoy some sightseeing.
Next, visit Vatican Museums, a globally renowned art museum that offers a unique experience.
When you’re done exploring for the day, you’ll drive to your hotel in Siena. Check in and spend some time relaxing before you head out to tour the city.
As dinnertime approaches, it's time to head out for a bite to eat in Siena. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.
Treat yourself to a delightful dinner at Enoteca I Terzi, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Ristorante Tar-Tufo? It's another excellent option with a diverse menu. Consider reserving a table at Antica Trattoria Papei as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Siena.
After your meal, keep the night alive at a bar like Meet Life Cafè, known for its lively atmosphere. Maudit Pub is another top recommendation that provides the perfect setting with well-crafted drinks and a welcoming ambiance. Similarly, Bar Impero Siena offers an excellent atmosphere for those looking to amp up the evening.
Get a good night's sleep and look forward to another great day on the road in Italy!
Day 6 – Siena, Pisa, and Florence
- Siena
- Pisa
- Florence
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Drive 222 km, 3 hours 29 min
- piazza del Campo
- Facciatone
- Siena Cathedral
- Piazza del Duomo, Pisa
- Leaning Tower of Pisa
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Embark on another extraordinary experience on day 6 of your road trip in Italy. Today, you will make 2 stops and experience some of the highlights of Siena and Pisa. At the end of the day, you will enjoy the comforts of a top-rated hotel in Florence, which will be your home away from home for 2 nights.
Enjoy the perfect balance of relaxation and exploration in Siena today. One of the most spectacular attractions included on the itinerary is Piazza Del Campo. This UNESCO world heritage-designated public square will help you start your sightseeing on top. Then, take a leisurely stroll to Facciatone and learn what makes this romantic observation deck unique.
Throughout the day, make sure to take breaks to appreciate the surroundings. Next up, visit the captivating Siena Cathedral.
When you’ve had your share of Siena, prepare for your next destination. Admire the views and listen to some good music as you drive in the direction of Pisa. Your travel time is around 1 hour 48 min.
Head to Piazza Del Duomo, Pisa, a wondrous public square in Pisa. Explore its stunning features at your own pace before you continue your journey to your next sight, Leaning Tower Of Pisa. This wondrous monument is a top recommendation in the area.
After soaking up all the sights of today's itinerary, you'll be ready to hit the road in the direction of your accommodation in Florence. Florence offers plenty of top-rated hotels and other places to stay on any travel budget. Take some time to relax before you head out to explore.
After a day of adventure, treat yourself to an exquisite dinner at one of Florence's best restaurants.
Dive into a culinary adventure like no other in Florence by booking a table at Enoteca Pinchiorri. This popular restaurant holds 3 Michelin star and offers an exceptional menu of italian contemporary cuisine. For another culinary dining option, venture to Santa Elisabetta, celebrated for its delectable creative and mediterranean menu. This acclaimed 2-star Michelin-recipient consistently leaves guests satisfied, ensuring an essential addition to your holiday itinerary. Seeking an alternative? Discover Gucci Osteria da Massimo Bottura, a top local restaurant known for its tantalizing italian contemporary and international menu. With a 1-star Michelin recognition, it promises an exceptional dining experience not to be missed.
After enjoying a delightful dinner, why not delve into the vibrant local bar scene? You might want to spend the evening at Manifattura, a well-loved spot among locals and tourists. Or, head to Se·sto On Arno Rooftop Bar. This bar boasts a welcoming environment that is perfect for winding down. You could also continue your night at Il Vinile, another top-rated place in the area.
Relax and recharge in preparation for another adventurous day in Italy!
Day 7 – Florence
- Florence
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Drive 4 km, 1 hour 6 min
- piazzale Michelangelo
- Basilica of Santa Croce in Florence
- piazza della Signoria
- Ponte Vecchio
- Uffizi Gallery
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Day 7 offers a multitude of experiences. You will stay in Florence for 1 night more, offering you enough time to explore at a relaxed pace.
Immerse yourself in Florence’s rich culture with today's sightseeing itinerary. Start your journey at Piazzale Michelangelo. This romantic observation deck is sure to ignite your curiosity. Next, dive into the photogenic features of Basilica Of Santa Croce In Florence, a must-visit church in the city.
In between sights, stop by local stores, picturesque photo spots, and small eateries. When you’re ready for your next attraction, proceed to Piazza Della Signoria, a top-rated public square. For a change of scene, check out Ponte Vecchio, known for its culturally significant features.
Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.
Indulge in a memorable dining experience at one of Florence's most popular restaurants, and connect with friendly locals for an authentic adventure.
Make sure to book a table at Ditta Artigianale, a popular restaurant in Florence. This acclaimed restaurant and its mouthwatering dishes have earned the admiration of countless food lovers. Alternatively, experience a taste of Florence at Trattoria Da Burde, a popular local restaurant. With a menu designed to impress, it promises a journey of flavors that will leave you captivated. Another top-rated restaurant to try is Casa Toscana. As a dining spot that gains high praise from guests, it’s an ideal choice to enhance your time to Florence tonight.
Cap off your dinner by heading to Bar 50 Rosso, ideal for a leisurely evening with a drink in hand. Bitter Bar is another bar that offers an enjoyable setting. Similarly, Archea Brewery is also a popular place to go on a night out, perfect for relaxing and socializing.
Head back to your accommodation in Florence and get some rest in preparation for another magical day of your road trip in Italy!
Day 8 – Florence, Santa Maria degli Angeli, and Perugia
- Florence
- Assisi
- Perugia
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Drive 194 km, 3 hours
- Cathedral of Santa Maria del Fiore
- Central Market
- Galleria dell'Accademia
- Basilica of San Francesco d'Assisi
- Ponte Vecchio
- More
On day 8 of your road trip in Italy, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Florence and Santa Maria degli Angeli. In the evening, you’ll end up in Perugia, where you will stay for 1 night.
Florence is home to plenty of attractions that offer a charming, a gorgeous, an eye-catching, a historically significant, a stunning, a grand, an UNESCO world heritage-designated, and a detailed! Start at Cathedral Of Santa Maria Del Fiore, a spectacular church that is worthwhile a visit in the city. Nearby, you’ll find Central Market, enchanting visitors with its instagrammable appeal. Continue your exploration at Galleria Dell'accademia. This art gallery is one of the city’s most captivating spots.
Continue your road trip and head to your next destination, Santa Maria degli Angeli. This car ride takes around 2 hours 7 min.
Begin your journey at Basilica Of San Francesco D'assisi and explore the historic features.
At the end of the day, you will drive to Perugia, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.
After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Perugia. Enjoy a satisfying meal that will recharge you for tonight's adventures.
Make sure to book a table at La Taverna, a popular restaurant in Perugia. This acclaimed restaurant and its mouthwatering dishes have earned the admiration of countless food lovers. Alternatively, experience a taste of Perugia at Ristorante del Sole, a popular local restaurant. With a menu designed to impress, it promises a journey of flavors that will leave you captivated. Another top-rated restaurant to try is Al Mangiar Bene. As a dining spot that gains high praise from guests, it’s an ideal choice to enhance your time to Perugia tonight.
Continue the enjoyment post-dinner at Caffè Fortebraccio, a cherished local gathering spot renowned for its welcoming atmosphere. Similarly, Caffe Del Banco offers a vibrant space for indulging in well-crafted drinks and engaging conversation. You may also want to check out Dempsey's Perugia. This bar is a favorite among both locals and visitors looking for a delightful evening out filled with laughter and fun.
Head back to your accommodation in Perugia and get some rest in preparation for another magical day of your road trip in Italy!
Day 9 – Perugia - departure day
- Perugia - Departure day
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- Rocca Paolina
- Etruscan Arch
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Day 9 of your road trip in Italy is your departure day. This is your chance to catch a last glimpse of Perugia before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.
As your final day in Italy unfolds, enjoy a last-minute shopping spree in Perugia's best shopping area. Enjoy finding the perfect gift or keepsake to remind you of your wonderful trip to Italy.
Set out on a day brimming with an instagrammable, a standout, and a symbolic. Start at the underrated Rocca Paolina, an eye-catching historical landmark in Perugia.
Before you conclude your road trip in Italy, drop by another restaurant for a last chance at a memorable dining experience in Perugia.
If you're in the mood for something new, try Elfo Pub Perugia, another premier location with a delectable menu.
You’ll then say farewell to Perugia. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Italy!
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