




Introduction
Simplify your search with this list of the top 10 places to stay in Syracuse! Every accommodation offers a great starting point for exploring the city. Learn more about what’s nearby and why these accommodations stand out in Syracuse.
Finding your ideal place to stay in Syracuse doesn't have to be a challenge. We've reviewed the biggest selection of hotels in Syracuse to bring you the 10 best places to stay, each offering something special for your trip.
While you're here, check out the most extensive range of tours and tickets in Syracuse.
Feeling overwhelmed? Skip the planning and browse customizable travel packages to Syracuse, designed to take the stress out of your trip.
Once you've chosen your must-visit attractions, the only thing left is picking your perfect stay. Scroll down for everything you need to know about where to stay in Syracuse and start planning your adventure today!
Top 5 Best Neighborhoods To Stay in Syracuse
Choosing the right neighborhood is key to having an enjoyable visit, and this guide to the best neighborhoods to stay in Syracuse will help you find the ideal area for your travel needs. Each neighborhood offers unique benefits, from access to attractions to affordability and convenience.
5. Eastwood – Quiet and Affordable
Eastwood is the best neighborhood to stay in Syracuse if you want a peaceful and budget-friendly experience. This area is known for its tree-lined streets and local shops. Accommodations here are mostly budget hotels and guesthouses, making it suitable for travelers looking to save money while staying a short drive from downtown.4. University Hill – Great for Students and Young Travelers
University Hill is the best area to stay if you want to be close to Syracuse University and the SUNY Upstate Medical University. The neighborhood offers affordable hotels, campus vibes, and easy access to college sports events and cafes. It’s a practical choice for prospective students or visitors attending university events.3. Northside – Cultural and Diverse
Northside is the best neighborhood to stay in Syracuse if you want to experience a multicultural atmosphere. Here, you’ll find authentic Italian bakeries, the famous Assumption Church, and a range of ethnic eateries. Lodging options include budget motels and B&Bs, making it ideal for food lovers and budget-conscious travelers.2. Armory Square – Trendy and Central
Armory Square is the best area to stay if you want to be in the heart of Syracuse’s nightlife and dining scene. This vibrant district features boutique hotels, craft breweries, and top-rated restaurants. Its central location makes it easy to walk to museums and entertainment venues, perfect for travelers who want convenience and a lively atmosphere.1. Downtown Syracuse – Best for First-Time Visitors
Downtown Syracuse is the best neighborhood to stay if you want proximity to major attractions like the Erie Canal Museum and Landmark Theatre. Accommodation options range from luxury hotels to modern apartments. Staying downtown provides easy access to public transport, shops, and historic sites, making it the top choice for most travelers.Explore Syracuse Stays
Choose your Syracuse stay style here. Browse by category to find your next stay in Syracuse.
Search for Places To Stay in Syracuse
Browse the largest selection of hotels and accommodations in Syracuse, all backed by a best-price guarantee. Whether you’re looking for a central location, pet-friendly options, or a place with a pool, simply enter your travel dates to find your perfect stay in Syracuse.
The 10 Best Places To Stay in Syracuse
Discover our updated list of the top 10 best places to stay in Syracuse, chosen for their exceptional comfort, top-rated service, and prime locations. From luxurious retreats to budget-friendly spots, there’s a hotel for every traveler.
Find your perfect base below and make your Syracuse adventure truly unforgettable!
10. Maison Ortigia

- Guest Rating: 4 out of 5 stars from 5092 reviews
- Location: Just 0.2 miles (0.3 km) from the city center
- Distance from Catania–Fontanarossa Airport: 32.3 miles (52 km)
- Nearest Attractions: Syracuse Cathedral and Island of Ortigia
- Check-in: 2:00 PM
- Check-out: 11:00 AM
- Starting Rate: 100 EUR
Located just 0.2 miles (0.3 km) from the city center, Maison Ortigia provides easy access to iconic landmarks like the remarkable Syracuse Cathedral and Island of Ortigia.
For those interested in activities, there are options such as hiking.
But that's just the beginning of what makes this bed & breakfast stand out. At Maison Ortigia, guests can expect a seamless and comfortable stay with practical amenities like air conditioning, 24-hour front desk, terrace, room service, family rooms, airport shuttle, and free Wi-Fi. Room prices at Maison Ortigia start from 100 EUR.
Thanks to its exemplary service, Maison Ortigia has become known for its exceptional hospitality and guest satisfaction. This, along with a combination of clean and well-designed accommodations, perfect location, and excellent value for money, makes Maison Ortigia one of the top choices when considering where to stay in Syracuse.
9. Apollo Suite

- Guest Rating: 4.5 out of 5 stars from 1095 reviews
- Location: Just 0.2 miles (0.3 km) from the city center
- Distance from Catania–Fontanarossa Airport: 31.9 miles (51.4 km)
- Nearest Attractions: Temple of Apollo and Mercato
- Check-in: 3:30 PM
- Check-out: 10:00 AM
- Starting Rate: 220 EUR
Guests at Apollo Suite benefit from a range of amenities, including room service, bar, family rooms, free Wi-Fi, and air conditioning. It offers value for money, with room rates starting from 220 EUR.
Apollo Suite has a convenient location, just 0.2 miles (0.3 km) from the city center. It provides easy access to landmarks such as Temple of Apollo and Mercato.
Located near prominent attractions, Apollo Suite offers a refined stay experience in Syracuse. Its commitment to comfort and quality service ensures that guests have a pleasant and relaxing visit.
8. Palazzo Artemide

- Comfort Level: 4-star hotel
- Guest Rating: 4.7 out of 5 stars from 610 reviews
- Location: Just 0.1 miles (0.2 km) from the city center
- Distance from Catania–Fontanarossa Airport: 32.3 miles (51.9 km)
- Nearest Attractions: Syracuse Cathedral and Island of Ortigia
- Check-in: 3:00 PM
- Check-out: 12:00 PM
- Starting Rate: 205 EUR
Conveniently located just 0.1 miles (0.2 km) from the city center, this hotel provides easy access to attractions like Syracuse Cathedral and Island of Ortigia.
Guests appreciate Palazzo Artemide for its excellent and functional amenities, including air conditioning, 24-hour front desk, garden, room service, family rooms, bar, restaurant, airport shuttle, sauna, and free Wi-Fi. The hotel also boasts a warm ambiance and guest-centered service.
During your stay, you can enjoy activities like bicycle rent.
At Palazzo Artemide, rooms are well-designed and priced from 205 EUR. Guests can look forward to a comfortable stay that enhances their overall experience in Syracuse.
7. Casale Milocca

- Comfort Level: 4-star hotel
- Guest Rating: 4.5 out of 5 stars from 1141 reviews
- Location: Just 3.8 miles (6.2 km) from the city center
- Distance from Catania–Fontanarossa Airport: 33.5 miles (53.9 km)
- Nearest Attractions: Playa Ognina and Cave of Pillirina
- Check-in: 2:00 PM
- Check-out: 10:00 AM
- Starting Rate: 114 EUR
The hotel is situated 3.8 miles (6.2 km) from the city center. Its perfect location places it near notable attractions like Playa Ognina and Cave of Pillirina, ensuring easy access to these points of interest.
Casale Milocca features essential amenities, including air conditioning, 24-hour front desk, garden, terrace, room service, family rooms, bar, airport shuttle, swimming pool, free Wi-Fi, restaurant, gym, sauna, hot tub, and spa. Room rates at this hotel start at 114 EUR.
With its blend of comfort, style, and prime location, Casale Milocca stands out as a top choice among travelers to Syracuse. Its thoughtful amenities and proximity to top attractions in the city make it a standout option for your visit.
6. Casa Verbavolant

- Guest Rating: 5 out of 5 stars from 372 reviews
- Location: Just 0.1 miles (0.1 km) from the city center
- Distance from Catania–Fontanarossa Airport: 32.2 miles (51.7 km)
- Nearest Attractions: Syracuse Cathedral and Island of Ortigia
- Check-in: 3:00 PM
- Check-out: 10:00 AM
- Starting Rate: 121 EUR
Conveniently located just 0.1 miles (0.1 km) from the city center, Casa Verbavolant makes it easy to visit popular attractions like Syracuse Cathedral and Island of Ortigia.
The guesthouse is highly regarded for its amenities, including air conditioning, room service, and free Wi-Fi.
Entertainment options such as board games ensure something for everyone.
Room rates at Casa Verbavolant start from 121 EUR. Overall, this property offers excellent value for money, making it suitable for travelers seeking a great experience.
5. Kyanos Residence

- Guest Rating: 4.6 out of 5 stars from 1003 reviews
- Location: Just 0.6 miles (1 km) from the city center
- Distance from Catania–Fontanarossa Airport: 31.5 miles (50.7 km)
- Nearest Attractions: Mercato and Old market of Ortigia
- Check-in: 3:00 PM
- Check-out: 10:00 AM
- Starting Rate: 124 EUR
This renowned vacation rental apartment boasts convenient amenities, including air conditioning, family rooms, and free Wi-Fi.
The vacation rental apartment's perfect location, just 0.6 miles (1 km) from Syracuse's dynamic center, allows easy access to standout attractions such as the top-rated Mercato and the captivating Old market of Ortigia.
Beyond its stylish and well-designed accommodations, Kyanos Residence captivates with its prompt and exemplary service. Overall, staying one night or two at Kyanos Residence during a trip to Syracuse offers a memorable experience and excellent value.
With Kyanos Residence, guests step into a world of extraordinary service and indulgent comfort. Room rates start from 124 EUR, making Kyanos Residence a standout choice for those deciding where to stay in Syracuse.
4. Agriturismo Papyrus

- Guest Rating: 4.6 out of 5 stars from 1025 reviews
- Location: Just 3.5 miles (5.6 km) from the city center
- Distance from Catania–Fontanarossa Airport: 31.7 miles (51 km)
- Nearest Attractions: Fonte Ciane and Tecnoparco Museo di Archimede
- Check-in: 2:30 PM
- Check-out: 11:00 AM
- Starting Rate: 161 EUR
Moreover, the location is perfect. Agriturismo Papyrus is just 3.5 miles (5.6 km) from the city center. You’ll find it conveniently close to attractions like Fonte Ciane and Tecnoparco Museo di Archimede.
In addition, the guesthouse offers convenient and functional amenities, including garden, family rooms, bar, free Wi-Fi, air conditioning, and swimming pool.
There are also fun activities to enjoy, including hiking.
Room rates at Agriturismo Papyrus start at 161 EUR. Overall, Agriturismo Papyrus provides a comfortable and convenient stay, making it one of the best guesthouse options in Syracuse.
3. Teocrito

- Comfort Level: 3-star hotel
- Guest Rating: 4.6 out of 5 stars from 1250 reviews
- Location: Just 1 mile (1.7 km) from the city center
- Distance from Catania–Fontanarossa Airport: 31.1 miles (50 km)
- Nearest Attractions: Basilica Santuario Madonna delle Lacrime and Museo Archeologico Regionale Paolo Orsi
- Check-in: 2:30 PM
- Check-out: 11:00 AM
- Starting Rate: 61 EUR
At the hotel, guests can enjoy amenities such as air conditioning, 24-hour front desk, room service, family rooms, bar, and free Wi-Fi.
Teocrito is situated 1 mile (1.7 km) from the city center. Nearby attractions like Basilica Santuario Madonna delle Lacrime and Museo Archeologico Regionale Paolo Orsi are easily accessible.
This superb hotel also offers entertainment options like board games and live sports events (broadcast) and activities such as hiking, fishing, and diving for those seeking an active experience.
Offering value for money, room rates start at 61 EUR for the cheapest options. Guests can expect both comfort and quality, no matter which option they choose.
2. Elsa d'Ortigia

- Guest Rating: 4.8 out of 5 stars from 730 reviews
- Location: Just 0.2 miles (0.3 km) from the city center
- Nearest Attractions: Galleria regionale di Palazzo Bellomo di Siracusa and Temple of Athena
- Check-in: 1:00 PM
- Check-out: 10:00 AM
This guesthouse places you just 0.2 miles (0.3 km) from the city center. Nearby attractions include Galleria regionale di Palazzo Bellomo di Siracusa and Temple of Athena.
Amenities at Elsa d'Ortigia include room service, 24-hour front desk, terrace, airport shuttle, free Wi-Fi, and air conditioning.
Recognized among the top 10 best places to stay in Syracuse, Elsa d'Ortigia ensures a memorable and comfortable experience for all guests.
1. Aretusa Vacanze

- Guest Rating: 4.8 out of 5 stars from 1236 reviews
- Location: Just 0.3 miles (0.5 km) from the city center
- Distance from Catania–Fontanarossa Airport: 31 miles (49.9 km)
- Nearest Attractions: Arethusa Spring and Galleria regionale di Palazzo Bellomo di Siracusa
- Check-in: 2:00 PM
- Check-out: 11:00 AM
- Starting Rate: 161 EUR
With its superior amenities, welcoming ambiance, and elegant rooms, Aretusa Vacanze is undeniably the number one place to stay in Syracuse. This bed & breakfast is renowned for its exceptional service and sets the highest standard for hospitality.
Situated just 0.3 miles (0.5 km) from the lively city center, Aretusa Vacanze's perfect location offers easy access to Syracuse's top attractions, including Arethusa Spring and Galleria regionale di Palazzo Bellomo di Siracusa.
Guests appreciate the top-notch amenities, including air conditioning, terrace, room service, family rooms, airport shuttle, and free Wi-Fi.
With room rates starting from 161 EUR, Aretusa Vacanze offers exceptional value. Guests seeking where to stay in Syracuse, Italy, will find Aretusa Vacanze delivers an experience that’s second to none.
What To Discover Next in Syracuse
Lodging at one of the best places to stay in Syracuse guarantees a comfortable and unforgettable experience in the city. But figuring out where to stay is just one piece of the puzzle.
Syracuse is a city of rich history, stunning architecture, and deep cultural roots, offering travelers an immersive experience. Explore the top things to do in Syracuse to not miss out on any of the best experiences. For a deeper dive into the city, follow one of the top travel itineraries for Syracuse.
From flights and rental cars to tours and tickets, the links below provide everything you need for a stress-free and enriching experience in Syracuse. Start planning today!