11-Day Italy Self-Drive Road Trip With Itinerary from Genoa traveling east to Florence, Siena, and Rome

On day 2 of your road trip, you’ll start and end your day in Genoa, where you'll stay for 1 night more.

Get ready for a day filled with family-friendly attractions, breathtaking views, and picturesque spots in the charming city of Genoa. Your adventure starts at Lighthouse Of Genoa, a beloved local hot spot. Another notable attraction to explore is Galata Museo Del Mare (complex). This worthwhile maritime museum is known for its breathtaking appeal.

After soaking in the highlights of these sights, take some time to wander Genoa's streets and immerse yourself in the local atmosphere. When you're ready to continue your sightseeing adventure, head to Via Garibaldi. This UNESCO world heritage-designated street offers a fascinating experience that many visitors find memorable. Porto Antico is also worth visiting, along with Church Of St. Anthony Of Boccadasse. These standout landmarks offer unique experiences that add to the day’s enjoyment. End your day at Spiaggia Pubblica Di Priaruggia. This worthwhile beach provides a fitting finale to your sightseeing.

When you’re done exploring for the day, you’ll return to Genoa and your accommodation.

As dinnertime approaches, it's time to head out for a bite to eat in Genoa. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Don’t miss out on dining at Zeffirino, a top-rated dining destination in Genoa. If you're in the mood to try something new, consider Trattoria Vegia Zena, another top spot with a mouthwatering menu. You might also want to secure a reservation at Trattoria delle Grazie. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Genoa this evening.

Relax and reminisce about your day in Italy and look forward to more memorable moments to come!

Experience an unparalleled adventure on day 3 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 1 vibrant destinations - Florence. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Florence. You will spend 2 nights here for some well-deserved relaxation.

Whether you prefer a leisurely exploration or a more fast-paced adventure, this itinerary in Genoa allows for both. Start by heading to Galleria Dell'accademia. This popular art gallery provides an insightful glimpse into the city's identity. Next, discover Riccardi Medici Palace, a historic palace, promising a delightful encounter.

Continue your sightseeing with a visit to Cathedral Of Santa Maria Del Fiore, a spectacular church. When you’re done, don’t forget to make a stop at the frequently visited Strozzi Palace Mantua.

At the end of the day, you will drive to Florence, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Florence. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Have a fantastic dining experience at Ristorante Oliviero 1962, a highly recommended choice for tonight's dinner. If you're looking to mix things up, Di Poneta Novoli offers an enticing alternative with its varied menu. Additionally, Caffe San Firenze is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Florence.

To truly maximize your evening out, consider visiting Manifattura after dinner. This bar is known for offering some of the best drinks and vibes in the city. Alternatively, head to Se·sto On Arno Rooftop Bar, another bar with an inviting ambiance. Similarly, Il Vinile also offers a great atmosphere, ensuring a night filled with enjoyment and relaxation.

Raise your glass to another unforgettable day in Italy!

On day 4 of your road trip, you will have an entire day to explore Florence. You’ll stay in Florence for 1 night and discover all the best things to see and do in the area.

Today’s agenda in Florence includes a historical landmark, an art gallery, a palace, a public square, a church, an observation deck and much more! Ponte Vecchio is must-visit historical landmark and a great starting point for the day. Next, continue your journey to Uffizi Gallery, a spectacular art gallery, located just a leisurely stroll away. Next, head to Palazzo Vecchio, a majestic palace, also available for your discovery today.

Each stop on today’s itinerary promises to leave you with lasting memories and a deeper appreciation for Florence. When you're ready, let your sightseeing route take you to the top-rated Piazza Della Signoria. If you’re looking for more, Basilica Of Santa Croce In Florence is also an interesting attraction that is worthwhile a visit. Lastly, don’t miss Piazzale Michelangelo, a place of romantic interest in the city.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

As dinnertime approaches, it's time to head out for a bite to eat in Florence. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Have a fantastic dining experience at Ditta Artigianale, a highly recommended choice for tonight's dinner. If you're looking to mix things up, Trattoria Da Burde offers an enticing alternative with its varied menu. Additionally, Casa Toscana is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Florence.

Cap off your dinner by heading to Bar 50 Rosso, ideal for a leisurely evening with a drink in hand. Bitter Bar is another bar that offers an enjoyable setting. Similarly, Archea Brewery is also a popular place to go on a night out, perfect for relaxing and socializing.

Raise your glass to another unforgettable day in Italy!

On day 5 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 1 destination, Siena. When you’re not sightseeing, take time to relax at your selected hotel in Siena, where you’ll be staying for 2 nights.

Discover a day packed with fun adventures, romantic experiences, and scenic views in Florence. Begin your sightseeing with Siena Cathedral. This well-known church is one of the top attractions in the city. Proceed to Battistero Di San Giovanni Battista, another must-visit attraction.

As you wander through the inviting streets of Florence, soak in the lively ambiance and take the opportunity to snap some photos. Next, head to Pubblico Palace. This underrated palace is a traveler-favorite. Not far away, you’ll find Piazza Del Campo, another key site on your sightseeing itinerary. Tower Of Mangia is yet another highly recommended place to visit nearby, offering plenty to discover for curious travelers.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Siena. Siena offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Siena. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Make sure to reserve a table at Enoteca I Terzi, an iconic dining spot in Siena. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Ristorante Tar-Tufo, a popular restaurant in Siena. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Antica Trattoria Papei, a hidden gem nestled in Siena. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Following your dinner, dive into the local bar culture at Meet Life Cafè. Enjoy this evening's relaxed ambiance with delightful drinks. Alternatively, go to Maudit Pub, the perfect place for those looking to experience the best of the nightlife. Similarly, Bar Impero Siena provides excellent drinks and a great atmosphere, ensuring a memorable night out.

As the sun sets on another day of adventure, rest up and recharge for the next leg of your road trip in Italy.

On day 6 of your road trip in Italy, you’ll start and end your day in Siena, but spend the day exploring what’s beyond the city. Since you will return to Siena for 1 night more, there’s no need to rush. Experience San Gimignano to the fullest today with this curated day itinerary!

Get ready for an exciting day in Siena. Today’s sightseeing agenda includes a monument, a museum, a public square, a castle, a church and much more! Begin your adventure at Porta San Giovanni. This is a worthwhile monument you should not miss. Another must-see is Sangimignano1300, an up-and-coming museum in Siena.

When you’re ready for the next sight, head to Palazzo Comunale, Pinacoteca, Torre Grossa. From there, take a leisurely stroll to Piazza Del Duomo, another of the village’s curiosity-inducing attractions. We recommend continuing your self-guided tour at Rocca Di Montestaffoli, an UNESCO world heritage-designated place of interest in the village. If time allows, add Chiesa Di Sant'agostino to your itinerary. This locally appreciated church offers the perfect finishing touch to your day in Siena.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Siena.

After a day of adventure, treat yourself to an exquisite dinner at one of Siena's best restaurants.

Have a fantastic dining experience at Osteria Quattro Venti, a highly recommended choice for tonight's dinner. If you're looking to mix things up, Fischi per Fiaschi offers an enticing alternative with its varied menu. Additionally, Osteria da Divo is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Siena.

Continue the enjoyment post-dinner at Charlie Mixology Bar Di Aldinucci Riccardo, a cherished local gathering spot renowned for its welcoming atmosphere. Similarly, Bar Pinacoteca offers a vibrant space for indulging in well-crafted drinks and engaging conversation. You may also want to check out San Paolo Pub. This bar is a favorite among both locals and visitors looking for a delightful evening out filled with laughter and fun.

Raise your glass and celebrate another amazing day of your road trip in Italy!

Embark on another extraordinary experience on day 7 of your road trip in Italy. Today, you will make 1 stop and experience some of the highlights of Rome. At the end of the day, you will enjoy the comforts of a top-rated hotel in Rome, which will be your home away from home for 3 nights.

Savor the day by visiting some of the best places to see in Siena, including an archeological site, a monument, and a public square. Start your adventure at Colosseum. This timeless archeological site is a must-visit for travelers looking for a unique holiday experience. Make your way to Roman Forum located in Siena for another exciting encounter.

Next, immerse yourself in the setting of Trevi Fountain. Its enchanting features will captivate you. After the monument, continue your tour of the city with a visit to Pantheon. Visitors usually appreciate the photogenic features of this monument. Next up is Capitoline Hill, a highly recommended public square.

When you’re done exploring for the day, you’ll drive to your hotel in Rome. Check in and spend some time relaxing before you head out to tour the city.

After a day of adventure, treat yourself to an exquisite dinner at one of Rome's best restaurants.

Treat yourself to a delightful dinner at La Bottega Roma, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Pasta In Corso? It's another excellent option with a diverse menu. Consider reserving a table at Trattoria Vecchia Roma as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Rome.

Continue your evening by exploring the vibrant nightlife scene at La Botticella Of Poggi Giovanni, a prime destination for a thrilling night out. Also, don’t forget to check out Almalu Trastevere, a bar that offers unique local touches. Likewise, Bar Viminale Di Pepi Maurilio provides an excellent alternative for a fun evening.

Say good night to Rome and look forward to another great day of your road trip in Italy!

On day 8 of your road trip, you’ll start and end your day in Rome, but spend part of the day exploring places of interest outside the immediate city. On today's itinerary, you'll find attractions in Vatican City and Rome. You still have 2 nights left in Rome.

Set aside time today to explore Trastevere, a standout neighborhood that reflects the essence of the city. While you're there, you'll also be within reach of some of the city's top landmarks, making it easy to maximize your day.

Continue your journey to St. Peter's Basilica, one of the city’s most timeless spots that you shouldn’t miss. Another great site to visit is the spectacular Campo De' Fiori. When you're finished at the public square, Piazza Navona awaits your visit. This public square is a culturally significant highlight on today's itinerary.

When you’re done exploring for the day, you’ll return to Rome and your accommodation.

As you explore more of Rome, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Treat yourself to a delightful dinner at RomAntica, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Coso Ristorante? It's another excellent option with a diverse menu. Consider reserving a table at DEROMA - Farine Romane as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Rome.

Round off your dining experience by visiting Sant' Eustachio Caffè, a prime location for a drink. Alternatively, explore the distinctive characteristics of Yellowsquare Rome, a bar catering to every mood and preference. Caffè Portofino likewise offers a unique atmosphere, perfect for a memorable night out.

Raise your glass to another unforgettable day in Italy!

At the end of the day, you'll drive back to Rome, where you'll stay for 1 night more.

Today, you'll explore some of the most beautiful places in Rome, including a park, a public square, and a church. Start your day with a visit to Villa Borghese. This astonishing park is a must-visit in the city. When you’re ready for your next discovery, continue to Passeggiata Del Pincio, which may be one of the most history-steeped places you will experience today.

One of the best things about exploring Rome on a self-guided tour is that you set the pace. There’s plenty of time for detours and discovering hidden gems. When you’re ready for your next stop, make your way to Spanish Steps, a famous public square in the city. If you’re up for more discoveries, don’t forget to reserve some time for Piazza Di Spagna and Basilica Di Santa Maria Maggiore. End your day with a visit to Frascati Cathedral, a locally appreciated church that’s sure to leave a lasting impression.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Rome.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Rome. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Dine in style at Hotel de Russie, a top recommendation for dinner tonight. Or, for a change of pace, La Taverna Italiana boasts a menu that's sure to impress. Also, be sure to check out The Parrot Bar. Known as a local hotspot, it’s a great choice for tonight in Rome.

After enjoying a fulfilling meal, continue your evening at The Apartment Bar Roma, ideal for those looking to unwind with a drink in a comfortable setting. Alternatively, Hotel Hassler Roma offers a welcoming atmosphere for easing into the nightlife.

Head back to your accommodation in Rome and get some rest in preparation for another magical day of your road trip in Italy!

On day 10 of your road trip in Italy, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Orvieto. In the evening, you’ll end up in Genoa, where you will stay for 1 night.

Start by visiting Well Of St. Patrick, a prime spot to begin your journey. This historic monument is sure to impress. Next on your list is Orvieto Cathedral, another must-visit landmark and interesting church renowned for its symbolic features.

While exploring and sightseeing, take time to savor the culture of Rome by sampling some local delicacies. When you’re ready for more sightseeing, head to Orvieto Underground. This heritage-rich cave system is an essential place to visit for anyone looking for the full Rome experience. We also recommend visiting Torre Del Moro Orvieto, a frequently visited monument. Nearby, you'll also find Pozzo Della Cava, ready to add charm to your journey.

At the end of the day, you will drive to Genoa, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As you explore more of Genoa, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Enjoy a lovely dining experience at Osteria Sant'Ilario, a popular restaurant in Genoa. This acclaimed establishment has earned the admiration of countless food lovers in the city. Alternatively, experience a taste of Genoa at La Cialtroneria, another great place to eat. With a menu designed to impress, it promises a journey of flavors that will leave you captivated. A third option to check out is the top-rated Manhattan Bar. It’s yet another ideal choice to enhance your time in Genoa tonight.

Savor another day of unforgettable experiences in Italy!