11-Day Italy Self-Drive Road Trip With Itinerary from Perugia traveling west to Rome, Siena, and Arezzo
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Explore the best of Italy on a 11-day road trip! Uncover hidden gems and experience the rich culture firsthand as you journey through Perugia, Rome, Siena, and Arezzo. This road trip itinerary in Italy seamlessly combines exploration with relaxation.
This perfectly planned road trip itinerary in Italy takes you through some of the best places to see in the country. You will spend 2 nights in Perugia, 4 nights in Rome, 2 nights in Siena, and 2 nights in Arezzo. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!
With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Italy. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have got you covered.
Upon arriving in Perugia, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Italy on your own terms.
An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Italy. Trevi Fountain and Colosseum are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Pantheon, learn more about the unique Piazza Navona, and immerse yourself in the vibrant atmosphere of St. Peter's Basilica.
As you hit the open road and drive through Perugia, Rome, Siena, and Arezzo, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Italy. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Italy.
Throughout your road trip in Italy, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Italy.
This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodation, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.
The best services in Italy fill up quickly, so book your spot early. Select a date and start planning your road trip in Italy today!
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Day 1
- Perugia - Arrival day
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- Piazza IV Novembre
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Say hello to Perugia! Your exciting road trip through Italy is just about to start. Navigating the top places to see in the region is a breeze with a car. The rental vehicle of your choice will be ready for pickup upon your arrival in the city. You will stay in Perugia for 1 night before you continue your adventure!
Perugia is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Piazza Iv Novembre, or just taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.
As afternoon approaches, head to your chosen hotel in Perugia. Check-in typically starts around 2 to 4 PM at hotels in Italy. We recommend staying at a hotel in a central location for easy access to the best attractions, restaurants, and bars in the city.
As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Perugia, it's often a good idea to reserve a table in advance.
Savor the flavors at Ristorante Settimo Sigillo, a top pick for dinner tonight. Alternatively, Caffè Baglioni beckons with its unique menu offerings. Also, consider Bar Pellas. With its consistent customer satisfaction, it’s an excellent option for dining in Perugia tonight.
After enjoying a fulfilling meal, continue your evening at Tommi Bar, ideal for those looking to unwind with a drink in a comfortable setting. Alternatively, Valentina offers a welcoming atmosphere for easing into the nightlife. Similarly, Caffe Dal Perugino provides an excellent environment for a relaxed and enjoyable evening.
Raise a toast to the start of your 11-day road trip in Italy!
Day 2
- Perugia
- Rome
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Drive 184 km, 2 hours 33 min
- Carducci Gardens
- Porta Marzia
- Rocca Paolina
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Experience an unparalleled adventure on day 2 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 1 vibrant destinations - Perugia. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Rome. You will spend 4 nights here for some well-deserved relaxation.
Get ready for a day filled with family-friendly attractions, romantic experiences, and scenic views in the charming city of Perugia. Your adventure starts at Carducci Gardens, an up-and-coming local hot spot. Another notable attraction to explore is Porta Marzia. This increasingly popular monument is known for its visually striking appeal.
After soaking in the highlights of these sights, take some time to wander Perugia's streets and immerse yourself in the local atmosphere. When you're ready to continue your sightseeing adventure, head to Rocca Paolina. This standout historical landmark offers a fascinating experience that many visitors find memorable.
When you’re done exploring for the day, you’ll drive to your hotel in Rome. Check in and spend some time relaxing before you head out to tour the city.
After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Rome. Enjoy a satisfying meal that will recharge you for tonight's adventures.
Have a memorable dining experience in Rome by booking a table at La Pergola, renowned as a 3-star Michelin restaurant presenting an exceptional mediterranean and contemporary menu. For a different culinary experience in Rome, Il Pagliaccio shines as one of the top destinations, known for its delicious creative and innovative cuisine. This 2-star Michelin-awardee earns consistently high praises from previous guests, making it a must-visit addition to your holiday experience. If you're looking for an alternative, Enoteca La Torre is known as a top local spot for its delicious mediterranean and creative cuisine in Rome. This 2-star Michelin awardee is a highly recommended choice for an unforgettable meal.
After your delicious meal, get a taste of the vibrant nightlife with a visit to La Botticella Of Poggi Giovanni, known for its inviting atmosphere. Almalu Trastevere is another great option if you’re looking for a place to get the night started. Similarly, Bar Viminale Di Pepi Maurilio provides a great setting to enjoy the night away.
As the sun sets on another day of adventure, rest up and recharge for the next leg of your road trip in Italy.
Day 3
- Rome
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Drive 8 km, 1 hour 2 min
- Trevi Fountain
- Pantheon
- Piazza Navona
- Campo de' Fiori
- Castel Sant'Angelo
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Day 3 of your road trip across Italy promises a magnificent time exploring Rome. You have 3 nights left in Rome. Take the opportunity to experience more of the best attractions and activities in the city.
Enjoy the perfect balance of relaxation and exploration in Rome today. One of the most wondrous attractions included on the itinerary is Trevi Fountain. This noteworthy monument will help you start your sightseeing on top. Then, take a leisurely stroll to Pantheon and learn what makes this culturally significant monument unique.
Throughout the day, make sure to take breaks to appreciate the surroundings. Next up, visit the timeless Piazza Navona. After exploring the public square, head to Campo De' Fiori. This spectacular public square is a highlight in Rome. As your day continues, stop by Castel Sant'angelo, known for its romantic features.
Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.
As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Rome. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.
Dine in style at RomAntica, a top recommendation for dinner tonight. Or, for a change of pace, Coso Ristorante boasts a menu that's sure to impress. Also, be sure to check out DEROMA - Farine Romane. Known as a local hotspot, it’s a great choice for tonight in Rome.
Continue your lively evening at Sant' Eustachio Caffè, a perfect place for winding down or revving up the night, depending on which mood you’re in. Yellowsquare Rome is another excellent bar that offers a great selection of drinks to suit any mood. If you prefer to go somewhere else, Caffè Portofino ensures a night out tailored to your taste.
Raise your glass and celebrate another amazing day of your road trip in Italy!
Day 4
- Rome
- More
Drive 8 km, 1 hour 14 min
- largo di Torre Argentina
- Altare della Patria
- Roman Forum
- Colosseum
- Basilica di Santa Maria Maggiore
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Day 4 of your road trip will take you to the best attractions Rome has to offer. Cherish the 2 nights you have left in Rome by discovering the best things there are to see and do in the city.
Set out on a day brimming with fun adventures, photo-friendly spots, and history-rich sites. Start at the interesting Largo Di Torre Argentina, a respected archeological site in Rome. Next, go to Altare Della Patria.
After visiting Largo Di Torre Argentina and Altare Della Patria, have a stroll along Rome's streets and take in the local charm. Continue your sightseeing by heading to Roman Forum. This historic archeological site offers a unique experience. Colosseum is another noteworthy attraction worthwhile a visit. End your self-guided sightseeing tour on top with a visit to Basilica Di Santa Maria Maggiore, one of the most heritage-rich places to visit in Rome.
Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.
After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Rome. Enjoy a satisfying meal that will recharge you for tonight's adventures.
Savor the flavors at Hotel de Russie, a top pick for dinner tonight. Alternatively, La Taverna Italiana beckons with its unique menu offerings. Also, consider The Parrot Bar. With its consistent customer satisfaction, it’s an excellent option for dining in Rome tonight.
Continue the enjoyment post-dinner at The Apartment Bar Roma, a cherished local gathering spot renowned for its welcoming atmosphere. Similarly, Hotel Hassler Roma offers a vibrant space for indulging in well-crafted drinks and engaging conversation.
Relax and recharge in preparation for another adventurous day in Italy!
Day 5
- Rome
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Drive 11 km, 1 hour 4 min
- Spanish Steps
- Piazza di Spagna
- piazza del Popolo
- Villa Borghese
- Circus Maximus
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On day 5 of your road trip, you will have an entire day to explore Rome. You’ll stay in Rome for 1 night and discover all the best things to see and do in the area.
Savor the day by visiting some of the best places to see in Rome, including a public square, a park, and an archeological site. Start your adventure at Spanish Steps. This famous public square is a must-visit for travelers looking for a unique holiday experience. Make your way to Piazza Di Spagna located in Rome for another exciting encounter.
Next, immerse yourself in the setting of Piazza Del Popolo. Its romantic features will captivate you. After the public square, continue your tour of the city with a visit to Villa Borghese. Visitors usually appreciate the standout features of this park. Next up is Circus Maximus, a highly recommended archeological site.
Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.
Indulge in a memorable dining experience at one of Rome's most popular restaurants, and connect with friendly locals for an authentic adventure.
Enjoy a delicious meal at Sofitel Roma Villa Borghese, a top-rated dining destination in Rome. If you're in the mood to try something new, consider Centro, another top spot with a mouthwatering menu. You might also want to secure a reservation at Ristorante Tema. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Rome this evening.
Relax and reminisce about your day in Italy and look forward to more memorable moments to come!
Day 6
- Rome
- Siena
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Drive 244 km, 3 hours 28 min
- St Peter's Basilica
- Sistine Chapel
- Saint Peter's Square
- Vatican Museums
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On day 6 of your road trip in Italy, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Vatican City. In the evening, you’ll end up in Siena, where you will stay for 2 nights.
Start your adventure at St. Peter's Basilica. This timeless major basilica is a place that is appreciated by travelers and locals alike.
Consider stopping for a small bite to eat or a drink at a local eatery to keep your energy going. When you’re ready, continue your discovery with a visit to Saint Peter's Square. This captivating square offers an enriching experience. These sights offer a fulfilling end to a perfect day.
After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Siena. Siena offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.
As you explore more of Siena, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.
Have a fantastic dining experience at Enoteca I Terzi, a highly recommended choice for tonight's dinner. If you're looking to mix things up, Ristorante Tar-Tufo offers an enticing alternative with its varied menu. Additionally, Antica Trattoria Papei is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Siena.
Continue the enjoyment post-dinner at Meet Life Cafè, a cherished local gathering spot renowned for its welcoming atmosphere. Similarly, Maudit Pub offers a vibrant space for indulging in well-crafted drinks and engaging conversation. You may also want to check out Bar Impero Siena. This bar is a favorite among both locals and visitors looking for a delightful evening out filled with laughter and fun.
Say good night to Siena and look forward to another great day of your road trip in Italy!
Day 7
- Siena
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Drive 2 km, 41 min
- Porta Romana
- Pubblico Palace
- piazza del Campo
- Tower of Mangia
- Siena Cathedral
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Day 7 offers a multitude of experiences. You will stay in Siena for 1 night more, offering you enough time to explore at a relaxed pace.
A blend of fun adventures, scenic views, and photo-friendly spots await you in Siena on today’s itinerary. First up is the often recommended monument, Porta Romana. Afterward, continue to Pubblico Palace, a palace every traveler should visit.
As you explore Siena’s charming streets, take in the lively atmosphere and get to know the character of the city. Next, make your way to Piazza Del Campo. This top-rated public square is an essential stop. Following that, head to Tower Of Mangia, another must-visit site that will enhance your experience. Don’t forget to stop by Siena Cathedral, an interesting church in the city.
Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.
After a day of adventure, treat yourself to an exquisite dinner at one of Siena's best restaurants.
Treat yourself to a delightful dinner at Osteria Quattro Venti, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Fischi per Fiaschi? It's another excellent option with a diverse menu. Consider reserving a table at Osteria da Divo as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Siena.
Keep the excitement of the evening going by visiting a bar or two. Charlie Mixology Bar Di Aldinucci Riccardo is an excellent place to start. You could also check out Bar Pinacoteca, offering a different kind of charm. A last recommendation for the day is San Paolo Pub. This bar promises an enjoyable experience with tasty drinks and a vibrant setting.
As the sun sets on another day of adventure, rest up and recharge for the next leg of your road trip in Italy.
Day 8
- Siena
- Arezzo
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Drive 74 km, 1 hour 45 min
- Palazzo Salimbeni
- Santuario di Santa Caterina
- Basilica of San Domenico
- Fortezza Medicea
- Porta Camollia, Siena
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Embark on another extraordinary experience on day 8 of your road trip in Italy. Today, you will make 1 stop and experience some of the highlights of Siena. At the end of the day, you will enjoy the comforts of a top-rated hotel in Arezzo, which will be your home away from home for 2 nights.
Savor the day by visiting some of the best places to see in Siena, including a palace, a church, and a monument. Start your adventure at Palazzo Salimbeni. This worthwhile palace is a must-visit for travelers looking for a unique holiday experience. Make your way to Santuario Di Santa Caterina located in Siena for another exciting encounter.
Next, immerse yourself in the setting of Basilica Of San Domenico. Its respected features will captivate you. After the church, continue your tour of the city with a visit to Fortezza Medicea (siena). Visitors usually appreciate the culturally significant features of this monument. Next up is Porta Camollia, Siena, a highly recommended monument.
At the end of the day, you will drive to Arezzo, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.
As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Arezzo. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.
Experience a taste of local culinary excellence while in Arezzo by securing a table at Octavin. An esteemed 1-star Michelin restaurant, it features an exceptional creative menu. If you're in the mood for something new, try La Clandestina, another premier location with a delectable menu.
Keep the excitement of the evening going by visiting a bar or two. Liquid Bar is an excellent place to start.
Relax and reminisce about your day in Italy and look forward to more memorable moments to come!
Day 9
- Arezzo
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Drive 2 km, 40 min
- Roman Amphitheatre of Arezzo
- San Francesco, Arezzo
- piazza Grande
- The Medici Fortress Park
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Day 9 of your road trip across Italy promises a magnificent time exploring Arezzo. You have 1 night left in Arezzo. Take the opportunity to experience more of the best attractions and activities in the city.
Arezzo is brimming with adventures. Today’s wonderful stops include an archeological site, a church, a public square, a park and much more! Begin your sightseeing adventure at the worthwhile Roman Amphitheatre Of Arezzo and allow yourself time to explore. Just a short distance away you'll find your next stop, San Francesco, Arezzo, a heritage-rich church that draws visitors from far and near.
Continue your journey to Piazza Grande, one of the city’s most interesting spots that you shouldn’t miss. Another great site to visit is the increasingly popular The Medici Fortress Park.
Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.
As you explore more of Arezzo, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.
Make sure to reserve a table at La Nuova Tagliatella, an iconic dining spot in Arezzo. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of i 3 bicchieri, a popular restaurant in Arezzo. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Il Cantuccio, a hidden gem nestled in Arezzo. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.
As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in in Italy.
Day 10
- Arezzo
- Perugia
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Drive 98 km, 1 hour 39 min
- Casa Vasari
- San Domenico
- Arezzo Cathedral
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Dive into day 10 of your remarkable road trip in Italy. Today you will explore Arezzo, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Perugia. You’ll stay here for 1 night.
Discover a day packed with family-friendly attractions, picturesque spots, and history-rich sites in Arezzo. Begin your sightseeing with Casa Vasari. This intriguing museum is one of the top attractions in the city. Proceed to San Domenico, another must-visit attraction.
As you wander through the inviting streets of Arezzo, soak in the lively ambiance and take the opportunity to snap some photos. Next, head to Arezzo Cathedral. This often recommended church is a traveler-favorite.
When you’re done exploring for the day, you’ll drive to your hotel in Perugia. Check in and spend some time relaxing before you head out to tour the city.
After a day of adventure, treat yourself to an exquisite dinner at one of Perugia's best restaurants.
Dine in style at La Taverna, a top recommendation for dinner tonight. Or, for a change of pace, Ristorante del Sole boasts a menu that's sure to impress. Also, be sure to check out Al Mangiar Bene. Known as a local hotspot, it’s a great choice for tonight in Perugia.
To truly maximize your evening out, consider visiting Caffè Fortebraccio after dinner. This bar is known for offering some of the best drinks and vibes in the city. Alternatively, head to Caffe Del Banco, another bar with an inviting ambiance. Similarly, Dempsey's Perugia also offers a great atmosphere, ensuring a night filled with enjoyment and relaxation.
Raise your glass to another unforgettable day in Italy!
Day 11
- Perugia - Departure day
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- Etruscan Arch
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Day 11 of your road trip in Italy is your departure day. This is your chance to catch a last glimpse of Perugia before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.
If you're up for some more sightseeing, begin at Etruscan Arch. This curiosity-inducing historical landmark is a popular place to see in the city.
Make the most of your final day in Italy by visiting Perugia’s iconic markets and shopping establishments. Secure the perfect souvenirs for your family and friends back home or buy yourself a remembrance of your amazing experience in Italy.
Before you conclude your road trip in Italy, drop by another restaurant for a last chance at a memorable dining experience in Perugia.
If you're in the mood to try something new, consider Elfo Pub Perugia, another top spot with a mouthwatering menu.
You’ll then say farewell to Perugia. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Italy!
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