12-Day Italy Self-Drive Road Trip With Itinerary from Brindisi to Lecce, Naples, and Rome
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Explore the best of Italy on a 12-day road trip! Uncover hidden gems and experience the rich culture firsthand as you journey through Brindisi, Lecce, Alberobello, Matera, Naples, Alberi, Positano, Furore, Amalfi, Ravello, and Rome. This road trip itinerary in Italy seamlessly combines exploration with relaxation.
This perfectly planned road trip itinerary in Italy takes you through some of the best places to see in the country. You will spend 2 nights in Brindisi, 4 nights in Lecce, 4 nights in Naples, and 1 night in Rome. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!
With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Italy. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have got you covered.
Upon arriving in Brindisi, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Italy on your own terms.
An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Italy. Trevi Fountain and Colosseum are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Pantheon, learn more about the unique Piazza Navona, and immerse yourself in the vibrant atmosphere of St. Peter's Basilica.
As you hit the open road and drive through Brindisi, Lecce, Alberobello, Matera, Naples, Alberi, Positano, Furore, Amalfi, Ravello, and Rome, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Italy. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Italy.
Throughout your road trip in Italy, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Italy.
This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodation, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.
The best services in Italy fill up quickly, so book your spot early. Select a date and start planning your road trip in Italy today!
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Day 1
- Brindisi - Arrival day
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- Colonne Romane
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Say hello to Brindisi! Your exciting road trip through Italy is just about to start. Navigating the top places to see in the region is a breeze with a car. The rental vehicle of your choice will be ready for pickup upon your arrival in the city. You will stay in Brindisi for 1 night before you continue your adventure!
Brindisi is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out End Of The Via Appia Antica, or just taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.
Find your way to your hotel in Brindisi. We recommend choosing a hotel in a central location for easy exploring. Check-in typically starts between 2 and 4 PM at hotels in Italy. Settle in and make plans for the evening.
As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Brindisi, it's often a good idea to reserve a table in advance.
Have a fantastic dining experience at Bracerie Escosazio, a highly recommended choice for tonight's dinner. If you're looking to mix things up, Penny offers an enticing alternative with its varied menu. Additionally, Piadineria is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Brindisi.
Extend your evening after a delightful meal by visiting Peddy Bar. Pasticceria. Gelateria. Happyhour. Prodotti Celiaci. Slot Machines. Scommesse, which offers the perfect atmosphere for a night out. Moreover, Eden Cafè is another popular option for a drink or two. Likewise, Altair Cafè also provides a great ambiance for reminiscing about the day and raising a toast to your vacation.
Raise a toast to the start of your 12-day road trip in Italy!
Day 2
- Brindisi
- Lecce
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Drive 39 km, 53 min
- Chiesa Rettoria del Santissimo Crocifisso
- Castello Carlo V
- Benedictine Monastery
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Dive into day 2 of your remarkable road trip in Italy. Today you will explore Brindisi and Lecce, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Lecce. You’ll stay here for 4 nights.
A blend of fun adventures, photo-friendly spots, and historic treasures await you in Brindisi on today’s itinerary. First up is the locally appreciated church, Chiesa Rettoria Del Santissimo Crocifisso. Afterward, continue to Castle Of Charles V, a castle every traveler should visit.
As you explore Brindisi’s charming streets, take in the lively atmosphere and get to know the character of the city. Next, make your way to Benedictine Monastery. This worthwhile monastery is an essential stop.
When you’re done exploring for the day, you’ll drive to your hotel in Lecce. Check in and spend some time relaxing before you head out to tour the city.
Indulge in a memorable dining experience at one of Lecce's most popular restaurants, and connect with friendly locals for an authentic adventure.
Treat yourself to a wonderful meal at Alle due Corti, a top-rated dining spot in Lecce. If you're in the mood for something new, try Il Ristoro dei Templari Trattoria Pizzeria Braceria, another premier location with a delectable menu. You might also want to book a table at La Cucina di Mamma Elvira. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Lecce.
Following your dinner, dive into the local bar culture at Sensi. Enjoy this evening's relaxed ambiance with delightful drinks. Alternatively, go to Caffè Alvino, the perfect place for those looking to experience the best of the nightlife. Similarly, Jolly Roger provides excellent drinks and a great atmosphere, ensuring a memorable night out.
Relax and reminisce about your day in Italy and look forward to more memorable moments to come!
Day 3
- Lecce
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Drive 0.7 km, 9 min
- Jewish Museum Lecce
- Basilica di Santa Croce
- Palazzo dei Celestini (Provincia di Lecce)
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Day 3 of your road trip will take you to the best attractions Lecce has to offer. Cherish the 3 nights you have left in Lecce by discovering the best things there are to see and do in the city.
Set out on a day brimming with fun adventures, picturesque spots, and history-rich sites. Start at the worthwhile Jewish Museum Lecce, an inviting museum in Lecce. Next, go to Basilica Di Santa Croce.
After visiting Jewish Museum Lecce and Basilica Di Santa Croce, have a stroll along Lecce's streets and take in the local charm. Continue your sightseeing by heading to Palazzo Dei Celestini (provincia Di Lecce). This respected palace offers a unique experience.
Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.
Indulge in a memorable dining experience at one of Lecce's most popular restaurants, and connect with friendly locals for an authentic adventure.
Treat yourself to a delightful dinner at Miro Coffee Bistrot & Lounge Bar, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Oscar Cafè? It's another excellent option with a diverse menu. Consider reserving a table at La Vecchia Osteria da Totu as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Lecce.
Round off your dining experience by visiting Bar Il Palio, a prime location for a drink. Alternatively, explore the distinctive characteristics of Al Ventuno, a bar catering to every mood and preference. Avio likewise offers a unique atmosphere, perfect for a memorable night out.
Take some time to reflect on your day and savor another beautiful night in Italy.
Day 4
- Lecce
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Drive 229 km, 2 hours 55 min
- Trullo Siamese monumento negozio souvenir
- Trulli di Alberobello Puglia
- Casa D'Amore
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On day 4 of your road trip in Italy, you’ll start and end your day in Lecce, but spend the day exploring what’s beyond the city. Since you will return to Lecce for 2 nights more, there’s no need to rush. Experience Alberobello to the fullest today with this curated day itinerary!
Get ready to discover some of the most iconic wonders in Lecce, including a gift shop and a historical landmark. Start your day at Trullo Siamese - Negozio Souvenirs. This photogenic gift shop is a curiosity-inducing place to see in Lecce. Then, wander over to Trulli Di Alberobello Puglia. If history-steeped sites excite you, this historical landmark will be right up your alley. Nearby, you’ll also find Casa D'amore. This breathtaking historical landmark is a favorite among visitors.
When you’re done exploring for the day, you’ll return to Lecce and your accommodation.
Indulge in a memorable dining experience at one of Lecce's most popular restaurants, and connect with friendly locals for an authentic adventure.
Don’t miss out on dining at L'OSTRICA UBRIACA di viale della Libertà, a top-rated dining destination in Lecce. If you're in the mood to try something new, consider L'angolino di Via Matteotti, another top spot with a mouthwatering menu. You might also want to secure a reservation at Bar L'Incontro | Caffetteria, Pasticceria, Rosticceria. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Lecce this evening.
Continue your lively evening at Quanto Basta, a perfect place for winding down or revving up the night, depending on which mood you’re in.
Head back to your accommodation in Lecce and get some rest in preparation for another magical day of your road trip in Italy!
Day 5
- Lecce
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Drive 381 km, 4 hours 31 min
- Sassi di Matera
- Sasso Caveoso
- Casa Grotta del Casalnuovo
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Greet day 5 of your road trip in Italy with a smile and start your day with a hearty breakfast. You will return to Lecce for your remaining 1 night in the city later today, but first, it’s time for some exploring! On the agenda for this day, you’ll find only the best things to see and do in Matera.
Whether you prefer a leisurely exploration or a more fast-paced adventure, this itinerary in Lecce allows for both. Start by heading to Sassi Di Matera. This interesting archeological site provides an insightful glimpse into the city's identity. Next, discover Sasso Caveoso, a visually striking cave system, promising a delightful encounter.
Continue your sightseeing with a visit to Casa Grotta Del Casalnuovo, a locally appreciated cave.
When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Lecce.
After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Lecce. Enjoy a satisfying meal that will recharge you for tonight's adventures.
Enjoy a delicious meal at Opera Lounge - Lecce, a highly-rated dining destination in Lecce. If you're eager to try something different, consider A'Roma l'Osteria, another top spot with a tantalizing menu. You might also want to secure a reservation at Bar Meeting Di Mattia De Vincenza. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Lecce this evening.
Relax and reminisce about your day in Italy and look forward to more memorable moments to come!
Day 6
- Lecce
- Naples
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Drive 414 km, 4 hours 28 min
- Castel Nuovo
- piazza del Plebiscito
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On day 6 of your road trip in Italy, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Naples. In the evening, you’ll end up in Naples, where you will stay for 4 nights.
Lecce is brimming with adventures. Today’s wonderful stops include a castle and a public square. Begin your sightseeing adventure at the notable Castel Nuovo and allow yourself time to explore. Just a short distance away you'll find your next stop, Piazza Del Plebiscito, a romantic public square that draws visitors from far and near.
At the end of the day, you will drive to Naples, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.
As you explore more of Naples, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.
Have a fantastic dining experience at L'Oca Nera Irish Pub, a highly recommended choice for tonight's dinner. If you're looking to mix things up, Mimì alla Ferrovia offers an enticing alternative with its varied menu. Additionally, Spuzzulè Winebar is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Naples.
After your delicious meal, get a taste of the vibrant nightlife with a visit to Happening Cocktail Bar, known for its inviting atmosphere. Shanti Art Musik Bar is another great option if you’re looking for a place to get the night started. Similarly, Gran Caffè Gambrinus provides a great setting to enjoy the night away.
Raise your glass and celebrate another amazing day of your road trip in Italy!
Day 7
- Naples
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Drive 11 km, 1 hour 22 min
- Castel Sant'Elmo
- Naples National Archaeological Museum
- Cappella Sansevero
- Napoli Sotterranea Percorso Ufficiale
- Cattedrale di Santa Maria Assunta
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Day 7 offers a multitude of experiences. You will stay in Naples for 3 nights more, offering you enough time to explore at a relaxed pace.
Today’s itinerary in Naples covers several incredible sights, including a castle, a museum, a cave system, a church and much more! Start your adventure at Castel Sant'elmo. This interesting castle is a place that is appreciated by travelers and locals alike. Next, immerse yourself in the noteworthy wonders of Naples National Archaeological Museum, a must-see museum in the city.
Consider stopping for a small bite to eat or a drink at a local eatery to keep your energy going. When you’re ready, continue your discovery with a visit to Cappella Sansevero. This interesting museum offers an enriching experience. For a change of pace, head to Napoli Sotterranea Percorso Ufficiale, where you can take in respected features. Conclude your self-guided sightseeing tour with a visit to Cattedrale Di Santa Maria Assunta. These sights offer a fulfilling end to a perfect day.
Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.
As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Naples. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.
Have a fantastic dining experience at Antica Pizzeria Di Matteo, a highly recommended choice for tonight's dinner. If you're looking to mix things up, Mercure Napoli Centro Angioino offers an enticing alternative with its varied menu. Additionally, La Lazzara Trattoria e Pizzeria is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Naples.
If you’re not ready to end the night just yet, Archivio Storico - Cocktail Bar & Wonderfood offers a perfect venue to relax and savor a drink. Similarly, Archeobar is well-suited for those looking to unwind in a social setting. Babette Pub is another excellent spot to enjoy a nightcap after a delightful meal.
Relax and reminisce about your day in Italy and look forward to more memorable moments to come!
Day 8
- Naples
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Drive 135 km, 3 hours 35 min
- Belvedere Sorrento
- Costiera Amalfitana Positano
- Fiordo di Furore
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On day 8 of your road trip, you’ll start and end your day in Naples, where you'll stay for 2 nights more.
Discover a day packed with fun adventures, romantic experiences, and breathtaking views in Naples. Begin your sightseeing with Belvedere Sorrento. This intriguing observation deck is one of the top attractions in the village. Proceed to Costiera Amalfitana Positano, another must-visit attraction.
As you wander through the inviting streets of Naples, soak in the lively ambiance and take the opportunity to snap some photos. Next, head to Fiordo Di Furore. This curiosity-inducing fjord is a traveler-favorite.
When you’re done exploring for the day, you’ll return to Naples and your accommodation.
As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Naples. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.
Treat yourself to a delicious dinner at Opera Restaurant, an excellent option for tonight's dining. Looking for something different? Trattoria San Ferdinando offers a tantalizing alternative with its diverse menu. And don’t miss Anonymous Trattoria Gourmet. With its reputation for pleasing customers, it’s a fantastic choice for tonight in Naples.
Cap off your dinner by heading to Gran Caffè Cimmino, ideal for a leisurely evening with a drink in hand. Flanagan's Bar is another bar that offers an enjoyable setting. Similarly, Bar Napoli is also a popular place to go on a night out, perfect for relaxing and socializing.
Savor another day of unforgettable experiences in Italy!
Day 9
- Naples
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Drive 123 km, 3 hours 11 min
- Amalfi Coast
- Villa Cimbrone Gardens
- Villa Rufolo
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Wake up to day 9 of your extraordinary road trip in Italy. With 1 night left in Naples, we encourage you to seize the day and discover the unexplored beauty of the city’s surroundings!
Enjoy the perfect balance of relaxation and exploration in Naples today. One of the most impressive attractions included on the itinerary is Amalfi Coast. Then, take a leisurely stroll to Villa Cimbrone Gardens and learn what makes this remarkable botanical garden unique.
Throughout the day, make sure to take breaks to appreciate the surroundings. Next up, visit the locally renowned Villa Rufolo.
When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Naples.
As dinnertime approaches, it's time to head out for a bite to eat in Naples. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.
Savor the flavors at Piazza Sannazaro, a top pick for dinner tonight. Alternatively, Osteria Il Gobbetto beckons with its unique menu offerings. Also, consider Trattoria Castel Nuovo. With its consistent customer satisfaction, it’s an excellent option for dining in Naples tonight.
After enjoying a delightful dinner, why not delve into the vibrant local bar scene? You might want to spend the evening at Parthenope Bar, a well-loved spot among locals and tourists. Or, head to Gran Caffè Mexico. This bar boasts a welcoming environment that is perfect for winding down. You could also continue your night at Novecento Wine Bar, another top-rated place in the area.
Say good night to Naples and look forward to another great day of your road trip in Italy!
Day 10
- Naples
- Rome
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Drive 232 km, 3 hours 26 min
- Colosseum
- Roman Forum
- Trevi Fountain
- Pantheon
- Piazza Navona
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On day 10 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 1 destination, Rome. When you’re not sightseeing, take time to relax at your selected hotel in Rome, where you’ll be staying for 1 night.
Whether you prefer a leisurely exploration or a more fast-paced adventure, this itinerary in Naples allows for both. Start by heading to Colosseum. This timeless archeological site provides an insightful glimpse into the city's identity. Next, discover Roman Forum, a historic archeological site, promising a delightful encounter.
Continue your sightseeing with a visit to Trevi Fountain, a wondrous monument. When you’re done, don’t forget to make a stop at the globally renowned Pantheon. Round off your day at Piazza Navona, another gem in Naples with visually striking features to discover.
After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Rome. Rome offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.
As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Rome. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.
Enjoy a delicious meal at La Bottega Roma, a top-rated dining destination in Rome. If you're in the mood to try something new, consider Pasta In Corso, another top spot with a mouthwatering menu. You might also want to secure a reservation at Trattoria Vecchia Roma. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Rome this evening.
Unwind after your meal by stepping into La Botticella Of Poggi Giovanni. This venue is celebrated for its extensive drink selections and cozy vibes. Alternatively, Almalu Trastevere offers a dynamic and energetic atmosphere for a glass or two. Don’t overlook Bar Viminale Di Pepi Maurilio, another top-rated bar in the area.
Savor another day of unforgettable experiences in Italy!
Day 11
- Rome
- Brindisi
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Drive 581 km, 6 hours 17 min
- St Peter's Basilica
- The Last Judgment
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Embark on another extraordinary experience on day 11 of your road trip in Italy. Today, you will make 1 stop and experience some of the highlights of Vatican City. At the end of the day, you will enjoy the comforts of a top-rated hotel in Brindisi, which will be your home away from home for 1 night.
Start by visiting St. Peter's Basilica, a prime spot to begin your journey.
When you’re done exploring for the day, you’ll drive to your hotel in Brindisi. Check in and spend some time relaxing before you head out to tour the city.
After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Brindisi. Enjoy a satisfying meal that will recharge you for tonight's adventures.
Make sure to reserve a table at Betty - Gelateria Cafe Ristorante Pizzeria a Brindisi, an iconic dining spot in Brindisi. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Bento, a popular restaurant in Brindisi. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Cozza Nera, a hidden gem nestled in Brindisi. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.
Take some time to reflect on your day and savor another beautiful night in Italy.
Day 12
- Brindisi - Departure day
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- Saint Pietro of Schiavoni Archeologica Area
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Day 12 of your road trip in Italy is your departure day. This is your chance to catch a last glimpse of Brindisi before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.
If you're up for some more sightseeing, begin at Saint Pietro Of Schiavoni Archeologica Area. This often recommended archeological site is a popular place to see in the city.
Maximize your last day in Italy and go on a shopping spree in Brindisi’s shopping center. Browse for souvenirs to remind you of your wonderful journey in Italy.
Before you conclude your road trip in Italy, drop by another restaurant for a last chance at a memorable dining experience in Brindisi.
Have a fantastic dining experience at Rendez-Vous Cafè Bistrot, a highly recommended choice for tonight's dinner. If you're looking to mix things up, Pizzeria La Nassa offers an enticing alternative with its varied menu.
You’ll then say farewell to Brindisi. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Italy!
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