5-Day Italy Self-Drive Road Trip With Itinerary from Ancona traveling south to L'aquila and Rome

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Photo of the long staircase in the downtown of the beautiful ancient italian village.
Photo of San Vittore alle Chiuse. Roman Catholic abbey and church. The edifice is known from the year 1011. Ponte Romano. Roman bridge over a small river. Italy. Marche. Ancona.
Photo of Loreto, sacred place in the city of Ancona in the Marche, Italy where the basilica sanctuary of the Holy House is located
Photo of Wonderful view of Arch of Trajan and Cattedrale di San Ciriaco church on background. Sunny summer cityscape of Ancona town, Italy, Europe. Traveling concept background.
Photo of Panorama view of the port of Ancona, Italy.
San Rocco Temple inside the pentagonal 18th century building called Mole Vanvitelliana at dusk. Ancona, Marche Region, Italy.
Photo of Urbani Beach - Sirolo, Ancona, Marche, Italy, Europe.
Photo of Ancona beach, Italy.
Photo of The harbor of Ancona with the rows of the boats docked and city view.
Photo of Panoramic view of old town and port in Ancona.
photo of view of Tourism in Ancona, Italy. Back view of traveler woman enjoying view of Ancona city and seaport from terrace, Marche, Italy.
photo of view of Night view of cathedral of San Ciriaco behind Arco di Traiano in Ancona, Italy.
photo of view of Mole Vanvitelliana also known as the lazaretto of Ancona.
photo of view of  Mole Vanvitelliana also known as the lazaretto of Ancona
Panoramic autumnal view in Barrea, province of L'Aquila in the Abruzzo region of Italy.
The Castle of Rocca Calascio is a mountaintop fortress or rocca in the municipality of Calascio, in the Province of L'Aquila, Abruzzo, Italy.
Basilica of Santa Maria di Collemaggio - L'Aquila - Italy
Beautiful panoramic view in the village of Barrea, province of L'Aquila in the Abruzzo region of Italy.
Lake San Domenico, in the Sagittario Gorges, in Abruzzo, L'Aquila, Italy. The small hermitage with the stone bridge. The turquoise color of the water. The glow of the sun, flare at sunset.
Gran Sasso freeway in Abruzzo,L-aquila, Italy
The enchanting Lake Scanno, in Abruzzo, in the province of L'Aquila, located between the Marsican Mountains. The small Church of Santa Maria dell'Annunziata overlooks the waters of the lake.
Scenic sight in Pescasseroli, Abruzzo National Park, province of L'Aquila. Italy
Santa Maria del Soccorso Church in Tagliacozzo, province of L'Aquila, Abruzzo, Italy.
The church of Santa Maria della Pietà is a religious building located in the municipality of Calascio, in the province of L'Aquila, in Abruzzo,
Colosseum, Rome, Italy.
Photo of piazza de spagna in Rome, Italy.
Photo of Fountain di Trevi in Rome, Italy.
Bridge Il Tevere a Ponte Vittorio Emanuele II in Rome, Italy.
Hadrian Mausoleum, Rome, Italy.
 Vatican dome of San Pietro and Sant Angelo Bridge, over Tiber river in Rome, Italy.
panoramic view of Rome and St. Peter's Basilica, Italy.
View of Pantheon in the morning, Rome, Italy.
Rome, Italy. Stunning twilight view of Forum ancient ruins, seen from Capitoline hill with Colosseum in background.
Aerial view of forum romanum and surrounding areas of historical centre of italian capital rome.
Cozy old street in Trastevere in Rome, Italy. Trastevere is rione of Rome, on the west bank of the Tiber in Rome, Lazio, Italy. Architecture and landmark of Rome.
Aerial panorama of St. Peter's Square in Vatican with Rome in the background. Italy.
photo of view of Illuminated Fontana Di Trevi, Trevi Fountain at Dusk, Rome, Italy.
photo of view of Spanish Step, Rome, Italy.
photo of view of Museum Luasanne, Rome, Italy.
photo of view Roma Wall of Lugo, Rome, Italy.
photo of view of Roman Bridge Cordoba, Rome, Italy.
photo of view of Roman ruins in Rome, Forum, Rome, Italy.
photo of view of Roman Bridge of Cordoba, Rome, Italy.
photo of view of The Iconic, the legendary Coliseum of Rome, Italy.
photo of view of Rome, Italy: The Roman Forum, Latin: Forum Romanum, Italian: Foro Romano, Rome, Italy.
photo of view of Trevi Fountain (Fontana di Trevi) in Rome, Italy. Trevi is most famous fountain of Rome. Architecture and landmark of Rome, Postcard of Rome, Italy.
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Explore the best of Italy on a 5-day road trip! Uncover hidden gems and experience the rich culture firsthand as you journey through Ancona, Senigallia, Loreto, L'aquila, Rome, Tivoli, and Teramo. This road trip itinerary in Italy seamlessly combines exploration with relaxation.

This perfectly planned road trip itinerary in Italy takes you through some of the best places to see in the country. You will spend 2 nights in Ancona, 1 night in L'aquila, and 1 night in Rome. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Italy. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have got you covered.

Upon arriving in Ancona, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Italy on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Italy. St. Peter's Basilica and Vatican Museums are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Sistine Chapel, learn more about the unique Saint Peter's Square, and immerse yourself in the vibrant atmosphere of Villa D'este.

As you hit the open road and drive through Ancona, Senigallia, Loreto, L'aquila, Rome, Tivoli, and Teramo, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Italy. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Italy.

Throughout your road trip in Italy, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Italy.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodation, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Italy fill up quickly, so book your spot early. Select a date and start planning your road trip in Italy today!

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Driver’s age is 30 - 65
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Days
Destination
Attractions
Overnight
Day
City & Overnight
Attractions
Passetto
Cattedrale di San CiriacoLazzaretto of AnconaRocca RoverescaSanctuary of the Holy House of Loreto
Vatican MuseumsSaint Peter's SquareSistine ChapelSt Peter's Basilica
Hadrian's VillaVilla d'EsteSantuario Madonna Delle Grazie
Piazza del Plebiscito

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Day 1

Day 1

  • Ancona - Arrival day
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  • Passetto
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Say hello to Ancona! Your exciting road trip through Italy is just about to start. Navigating the top places to see in the region is a breeze with a car. The rental vehicle of your choice will be ready for pickup upon your arrival in the city. You will stay in Ancona for 1 night before you continue your adventure!

Ancona is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Passetto, or just taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

Make your way to your chosen hotel. Check-in typically starts between 2 and 4 PM in Ancona. Make yourself at home and enjoy some downtime before heading out again.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Ancona, it's often a good idea to reserve a table in advance.

Savor the flavors at Playa Solero, a top pick for dinner tonight. Alternatively, Zucchero a Velò beckons with its unique menu offerings. Also, consider Ristorante Il Giardino. With its consistent customer satisfaction, it’s an excellent option for dining in Ancona tonight.

Cap off your dinner by heading to Posa Bar, ideal for a leisurely evening with a drink in hand. Bar Four Roses is another bar that offers an enjoyable setting. Similarly, Amarillo Beer Bar Ancona is also a popular place to go on a night out, perfect for relaxing and socializing.

Raise a toast to the start of your 5-day road trip in Italy!

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Day 2

Day 2

  • Ancona
  • L'Aquila
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Drive 257 km, 3 hours 57 min

  • Cattedrale di San Ciriaco
  • Lazzaretto of Ancona
  • Rocca Roveresca
  • Sanctuary of the Holy House of Loreto
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Embark on another extraordinary experience on day 2 of your road trip in Italy. Today, you will make 3 stops and experience some of the highlights of Ancona, Senigallia, and Loreto. At the end of the day, you will enjoy the comforts of a top-rated hotel in L'aquila, which will be your home away from home for 1 night.

Ancona is home to plenty of attractions that offer fun adventures, breathtaking views, and photo-friendly spots! Start at Cathedral Basilica Of St. Cyriacus, a frequently visited church that is worthwhile a visit in the city. Nearby, you’ll find Lazzaretto Of Ancona, enchanting visitors with its heritage-rich appeal. Continue your exploration at Rocca Roveresca. This castle is one of the city’s most increasingly popular spots.

Enjoy the freedom of exploring Ancona at your own pace and find hidden gems along the way. If you want to see more picture-perfect spots, make sure to visit Sanctuary Of The Holy House Of Loreto.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in L'aquila. L'aquila offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in L'aquila. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Get ready for an unforgettable culinary journey in L'aquila by reserving a table at FØRMA contemporary restaurant. Renowned as a Bib Gourmand restaurant, it offers an exceptional contemporary and creative menu. If you're in the mood to try something new, consider DECA, another top spot with a mouthwatering menu.

To truly maximize your evening out, consider visiting Art Cafè L'aquila after dinner. This bar is known for offering some of the best drinks and vibes in the city.

Savor another day of unforgettable experiences in Italy!

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Day 3

Day 3

  • L'Aquila
  • Rome
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Drive 135 km, 2 hours 21 min

  • Vatican Museums
  • Saint Peter's Square
  • Sistine Chapel
  • St Peter's Basilica
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Dive into day 3 of your remarkable road trip in Italy. Today you will explore Vatican City, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Rome. You’ll stay here for 1 night.

Start by visiting Vatican Museums, a prime spot to begin your journey.

We also recommend visiting St. Peter's Basilica, a timeless major basilica.

When you’re done exploring for the day, you’ll drive to your hotel in Rome. Check in and spend some time relaxing before you head out to tour the city.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Rome. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Have a memorable dining experience in Rome by booking a table at La Pergola, renowned as a 3-star Michelin restaurant presenting an exceptional mediterranean and contemporary menu. For a different culinary experience in Rome, Il Pagliaccio shines as one of the top destinations, known for its delicious creative and innovative cuisine. This 2-star Michelin-awardee earns consistently high praises from previous guests, making it a must-visit addition to your holiday experience. If you're looking for an alternative, Enoteca La Torre is known as a top local spot for its delicious mediterranean and creative cuisine in Rome. This 2-star Michelin awardee is a highly recommended choice for an unforgettable meal.

Continue your evening by exploring the vibrant nightlife scene at La Botticella Of Poggi Giovanni, a prime destination for a thrilling night out. Also, don’t forget to check out Almalu Trastevere, a bar that offers unique local touches. Likewise, Bar Viminale Di Pepi Maurilio provides an excellent alternative for a fun evening.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in in Italy.

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Day 4

Day 4

  • Rome
  • Ancona
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Drive 318 km, 4 hours 12 min

  • Hadrian's Villa
  • Villa d'Este
  • Santuario Madonna Delle Grazie
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On day 4 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 2 destinations, Tivoli and Teramo. When you’re not sightseeing, take time to relax at your selected hotel in Ancona, where you’ll be staying for 1 night.

Today’s route brings fun adventures, breathtaking views, and picturesque spots. The first attraction of today is Hadrian's Villa. This locally appreciated archeological site is a breathtaking place to see in Rome. Continue your discovery at Villa D'este, an UNESCO world heritage-designated palace with stories to tell.

As you stroll around Rome, take in the distinct atmosphere and learn what makes this town so unique. Maximize your sightseeing with a visit to Santuario Madonna Delle Grazie. This locally appreciated church offers a photogenic encounter with Rome. Whether you decide to get entrance tickets for all attractions or you prefer admiring from a distance, amazing experiences await on this day in Rome.

At the end of the day, you will drive to Ancona, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

Indulge in a memorable dining experience at one of Ancona's most popular restaurants, and connect with friendly locals for an authentic adventure.

Set out on a gastronomic journey in Ancona by reserving a table at Sot'Ajarchi. Renowned for its Bib Gourmand award, this restaurant presents an outstanding menu of seafood and from the marches cuisine. Looking for something different? Bontà delle Marche offers a tantalizing alternative with its diverse menu. With its reputation for pleasing customers, it’s a fantastic choice for tonight in Ancona.

Round off your dining experience by visiting Alla Tazza D'oro, a prime location for a drink.

Head back to your accommodation in Ancona and get some rest in preparation for another magical day of your road trip in Italy!

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Day 5

Day 5

  • Ancona - Departure day
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  • Piazza del Plebiscito
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Day 5 of your road trip in Italy is your departure day. This is your chance to catch a last glimpse of Ancona before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, begin at Piazza Del Plebiscito. This frequently visited public square is a popular place to see in the city.

As your final day in Italy unfolds, enjoy a last-minute shopping spree in Ancona's best shopping area. Enjoy finding the perfect gift or keepsake to remind you of your wonderful trip to Italy.

Before you conclude your road trip in Italy, drop by another restaurant for a last chance at a memorable dining experience in Ancona.

Enjoy a lovely meal at Pizzeria Pulcinella, a top-rated place to have dinner tonight. Alternatively, if your taste buds call for something different, Donegal Irish Pub is another top choice with a popular menu.

You’ll then say farewell to Ancona. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Italy!

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