5-Day Sicily Self-Drive Road Trip With Itinerary from Palermo to Agrigento and surrounding area

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Photo of Palermo, Sicily, Italy. Seafront view.
Photo of Palermo Norman cathedral, a UNESCO world heritage site in Italy, colored sunset sky.
Photo of Cefalu, medieval village of Sicily island, Province of Palermo, Italy.
Cefalu is city in Italian Metropolitan City of Palermo located on Tyrrhenian coast of Sicily, Italy.
Photo of Quattro Canti, Piazza Vigliena, is a Baroque square in Palermo, Sicily, Italy.
Photo of Palermo Cathedral in Palermo, Italy in a beautiful summer day.
Photo of Famous fountain of shame on baroque Piazza Pretoria, Palermo, Sicily, Italy.
Photo of Palermo street market. In Palermo is a very popular open air street market.
Photo of The Norman Cathedral, world heritage site in Italy, view from the roof.
Photo of Villa Bonnano public gardens and the palace at dawn.
View of Charleston, the Mondello beach establishment on the sea in Palermo, Sicily, Italy.
Fishing boats on beach of Cefalu, medieval town on Sicily island, Italy. Seashore village with historic buildings, clear turquoise sea water and mountains. Popular tourist attraction near Palermo.
Palermo, Sicily town skyline with landmark towers in the morning.
The Teatro Massimo in Palermo. Sicily, southern Italy.
Photo of view from flying drone. Aerial view of Sciacca town and beaches, province of Agrigento.
Photo of sandy beach under famed white cliff, called "Scala dei Turchi", in Sicily, near Agrigento, Italy.
Photo of sandy beach under famed white cliff, called "Scala dei Turchi", in Sicily, near Agrigento, Italy.
Photo of public beach near The Scala dei Turchi near Agrigento.
Photo of beautiful seascape with clear turquoise water on the beach Torre Salsa, Siculiana, Agrigento Sicily, Italy.
Photo of sandy beach under famed white cliff, called "Scala dei Turchi", in Sicily, near Agrigento, Italy.
Photo of Italy, Sicily, Agrigento, Valley of the Temples, Temple of Juno Lacinia.
Photo of  Province of Agrigento, Italy.
Photo of Post Office in Agrigento.
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Explore the best of Sicily on a 5-day road trip! Uncover hidden gems and experience the rich culture firsthand as you journey through Palermo, Agrigento, Xitta, and Castellammare del Golfo. This road trip itinerary in Sicily seamlessly combines exploration with relaxation.

This perfectly planned road trip itinerary in Sicily takes you through some of the best places to see in the country. You will spend 3 nights in Palermo and 1 night in Agrigento. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Sicily. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have got you covered.

Upon arriving in Palermo, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Sicily on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Sicily. Palermo Cathedral and Quattro Canti are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Norman Palace, learn more about the unique Catacombe Dei Cappuccini, and immerse yourself in the vibrant atmosphere of Foro Italico.

As you hit the open road and drive through Palermo, Agrigento, Xitta, and Castellammare del Golfo, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Sicily. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Sicily.

Throughout your road trip in Sicily, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Sicily.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodation, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Sicily fill up quickly, so book your spot early. Select a date and start planning your road trip in Sicily today!

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Driver’s age is 30 - 65
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Itinerary summary

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Days
Destination
Attractions
Overnight
Day
City & Overnight
Attractions
Foro Italico
Fontana PretoriaQuattro CantiChurch of St. Mary of the AdmiralRiserva Naturale di Capo GalloSantuario di Santa Rosalia, Palermo
Norman PalacePalermo CathedralOrto botanico di PalermoCatacombe dei Cappuccini
Saline di Trapani e PacecoRiserva Naturale Orientata dello ZingaroBelvedere Castellammare del GolfoMarina di Castellammare del Golfo
Garden Zisa

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Day 1

Day 1

  • Palermo - Arrival day
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  • Foro Italico
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Say hello to Palermo! Your exciting road trip through Italy is just about to start. Navigating the top places to see in the region is a breeze with a car. The rental vehicle of your choice will be ready for pickup upon your arrival in the city. You will stay in Palermo for 2 nights before you continue your adventure!

Palermo is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Foro Italico, or just taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

As afternoon approaches, head to your chosen hotel in Palermo. Check-in typically starts around 2 to 4 PM at hotels in Italy. We recommend staying at a hotel in a central location for easy access to the best attractions, restaurants, and bars in the city.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Palermo, it's often a good idea to reserve a table in advance.

Make sure to reserve a table at Cotto e Bollito, an iconic dining spot in Palermo. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Bebop, a popular restaurant in Palermo. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Eremiti Restaurant, a hidden gem nestled in Palermo. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Extend your evening after a delightful meal by visiting Malox Cult, which offers the perfect atmosphere for a night out. Moreover, Ai Giudici is another popular option for a drink or two. Likewise, Bar Italico also provides a great ambiance for reminiscing about the day and raising a toast to your vacation.

Raise a toast to the start of your 5-day road trip in Sicily!

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Day 2

Day 2

  • Palermo
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Drive 50 km, 2 hours 10 min

  • Fontana Pretoria
  • Quattro Canti
  • Church of St. Mary of the Admiral
  • Riserva Naturale di Capo Gallo
  • Santuario di Santa Rosalia, Palermo
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Day 2 of your road trip will take you to the best attractions Palermo has to offer. Cherish the 1 night you have left in Palermo by discovering the best things there are to see and do in the city.

Today’s agenda in Palermo includes a monument, a public square, a church, a nature reserve and much more! Fontana Pretoria is must-visit monument and a great starting point for the day. Next, continue your journey to Quattro Canti, an interesting public square, located just a leisurely stroll away. Next, head to Martorana, a symbolic church, also available for your discovery today.

Each stop on today’s itinerary promises to leave you with lasting memories and a deeper appreciation for Palermo. When you're ready, let your sightseeing route take you to the underrated Riserva Naturale Di Capo Gallo. If you’re looking for more, Santuario Di Santa Rosalia, Palermo is also an intriguing attraction that is worthwhile a visit.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Sicily is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

After a day of adventure, treat yourself to an exquisite dinner at one of Palermo's best restaurants.

Experience a taste of local culinary excellence while in Palermo by securing a table at Buatta Cucina Popolana. An esteemed Bib Gourmand restaurant, it features an exceptional sicilian menu. For an alternative taste experience, visit Mec Restaurant, famous for its scrumptious sicilian and contemporary dishes. This 1-star Michelin venue consistently impresses guests, making it a standout addition to your holiday plans. Looking for another choice? Discover Gagini Restaurant, a local favorite celebrated for its exquisite creative and contemporary cuisine in Palermo. Located in the heart of the city, this 1-star Michelin restaurant is an ideal pick for creative and contemporary cuisine lovers seeking top-notch culinary experiences.

Let the evening flow smoothly from dinner to drinks at Spina Bar Palermo, a top-rated bar in the area. For other recommendations, Torrefazione Castagnetta Massimiliano (gelateria) provides a perfect setting for rounding out your night with style and great drinks. Likewise, Monkey Pub offers a memorable night with diverse drink options and excellent service.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in in Sicily.

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Day 3

Day 3

  • Palermo
  • Agrigento
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Drive 137 km, 2 hours 31 min

  • Norman Palace
  • Palermo Cathedral
  • Orto botanico di Palermo
  • Catacombe dei Cappuccini
  • More

Embark on another extraordinary experience on day 3 of your road trip in Sicily. Today, you will make 1 stop and experience some of the highlights of Palermo. At the end of the day, you will enjoy the comforts of a top-rated hotel in Agrigento, which will be your home away from home for 1 night.

A blend of family-friendly attractions, scenic views, and photo-friendly spots await you in Palermo on today’s itinerary. First up is the notable palace, Norman Palace. Afterward, continue to Palermo Cathedral, a church every traveler should visit.

As you explore Palermo’s charming streets, take in the lively atmosphere and get to know the character of the city. Next, make your way to Orto Botanico Di Palermo. This beloved botanical garden is an essential stop. Following that, head to Catacombe Dei Cappuccini, another must-visit site that will enhance your experience.

At the end of the day, you will drive to Agrigento, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As dinnertime approaches, it's time to head out for a bite to eat in Agrigento. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Have a fantastic dining experience at Ambasciata di Sicilia, a highly recommended choice for tonight's dinner. If you're looking to mix things up, Le Cuspidi offers an enticing alternative with its varied menu. Additionally, Yellove RistoVintage is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Agrigento.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in in Sicily.

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Day 4

Day 4

  • Agrigento
  • Palermo
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Drive 312 km, 4 hours 40 min

  • Saline di Trapani e Paceco
  • Riserva Naturale Orientata dello Zingaro
  • Belvedere Castellammare del Golfo
  • Marina di Castellammare del Golfo
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Experience an unparalleled adventure on day 4 of your road trip in Sicily. This exciting part of your journey invites you to discover the renowned landmarks in 3 vibrant destinations - Xitta, San Vito Lo Capo, and Castellammare del Golfo. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Palermo. You will spend 1 night here for some well-deserved relaxation.

Get ready for a day filled with fun adventures, romantic experiences, and natural wonders in the charming village of Agrigento. Your adventure starts at Saline Di Trapani E Paceco, an intriguing local hot spot. Another notable attraction to explore is Riserva Naturale Orientata Dello Zingaro, Ingresso Sud. This up-and-coming nature reserve is known for its respected appeal.

After soaking in the highlights of these sights, take some time to wander Agrigento's streets and immerse yourself in the local atmosphere. When you're ready to continue your sightseeing adventure, head to Belvedere Castellammare Del Golfo. This stunning observation deck offers a fascinating experience that many visitors find memorable. Marina Di Castellammare Del Golfo is also worth visiting.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Palermo. Palermo offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Palermo. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Make sure to reserve a table at Splendid Hotel la Torre, an iconic dining spot in Palermo. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Ristorantino Sobremesa, a popular restaurant in Palermo. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Ristorante Quattro mani, a hidden gem nestled in Palermo. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

To truly maximize your evening out, consider visiting Bar Touring after dinner. This bar is known for offering some of the best drinks and vibes in the city. Alternatively, head to Palermo Football Store, another bar with an inviting ambiance. Similarly, Goccio - L’arte Del Miscelare also offers a great atmosphere, ensuring a night filled with enjoyment and relaxation.

Raise your glass and celebrate another amazing day of your road trip in Sicily!

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Day 5

Day 5

  • Palermo - Departure day
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  • Garden Zisa
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Day 5 of your road trip in Sicily is your departure day. This is your chance to catch a last glimpse of Palermo before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, begin at Giardino Della Zisa. This locally appreciated park is a popular place to see in the city.

As your final day in Sicily unfolds, enjoy a last-minute shopping spree in Palermo's best shopping area. Enjoy finding the perfect gift or keepsake to remind you of your wonderful trip to Sicily.

Before you conclude your road trip in Sicily, drop by another restaurant for a last chance at a memorable dining experience in Palermo.

You’ll then say farewell to Palermo. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Sicily!

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