One-Week Italy Self-Drive Road Trip With Itinerary from Brindisi traveling west to Alberobello, Matera, Naples, and Rome

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Ostuni white town skyline at sunset, Brindisi, Apulia southern Italy. Europe.
Ostuni white town skyline at sunset, Brindisi, Apulia southern Italy. Europe.
A sidewalk cafe with covered patio at the seaside promenade and boardwalk in the city of Brindisi, Italy, in the Puglia region.
Alfonsino castle, located at the entrance to the port of the Italian town of Brindisi, is an interesting example of defensive architecture.
Empty streets and closed shops and cafes on a summer morning on the main street, Corso Umberto, through the town center of the coastal city of Brindisi, Italy.
Photo of Brindisi harbour.
Morning as tourists begin to explore the Brindisi Duomo Cathedral and Bell tower in the Piazza Duomo in Brindisi, Italy, part of the southern Puglia region.
military monument seen from the harbor of Brindisi
photo of view of Panoramic view of Brindisi. Puglia. Italy.
photo of view of Brindisi, Italy.
photo of view of Barletta, Brindisi, Italy.
photo of view of Seafront. Brindisi. Puglia. Italy.
photo of view of Panoramic view of Ostuni white town, Brindisi, Puglia (Apulia), Italy,
photo of view of Piazza Duomo with Brindisi Cathedral near Archiological museum, Brindisi, Italy.
Photo of best view of the Matera skyline, Italy.
Photo of aerial view of Matera, Puglia, Italy.
Photo of St. Francesco d'Assisi Church, Matera, Italy.
Photo of buildings in the old town of Matera, Basilicata, Southern Italy with blue sky and white clouds.
Photo of the church of Madonna de Idris ( Chiesa Rupestre di Santa Maria di Idris ) in the rock. Cave church in Sassi old town, Matera, Italy.
Photo of night view of the St. Domenico church and Materdomini church over the Hypogeum ruins in the city centre ,Matera, Italy.
Photo of church of Madonna della Bruna and Sant'Eustachio, Matera Cathedral ,Italy.
Photo of panoramic view of the ancient town of Matera (Sassi di Matera) illuminated during beautiful evening twilight at dusk, Basilicata, southern Italy.
Photo of Matera old town view in Italy.
Photo of the medieval church of San Giovanni Battista (Saint John the Baptist) Matera, Basilicata, Italy.
Photo of art museum located inside the building Palazzo Lanfranchi, which is located in Piazzetta Pascoli, in the Historic Centre of Matera Basilicata, Italy.
Photo of happy tourist girl with arms raised up enjoys the stunning view of the Sassi di Matera in Italy.
Photo of historic Town of Matera ,Italy.
Photo of the ancient town of Matera (Sassi di Matera), European Capital of Culture 2019, in beautiful golden morning light with blue sky and clouds, Basilicata, southern Italy.
Photo of historic Town of Matera ,Italy.
Twilight panorama of Naples in Italy
Photo of Morning view of Amalfi cityscape on coast line of mediterranean sea, Italy.
Photo of View of Piazza del Plebiscito, Naples,Italy.
Panoramic view of the ancient city of Pompeii with houses and streets. Pompeii is an ancient Roman city died from the eruption of Mount Vesuvius in the 1st century. Naples, Italy.
Photo of Panorama of Naples, view of the port in the Gulf of Naples and Mount Vesuvius. The province of Campania. Italy.
Photo of Maschio Angioino Castle in Naples during a sunny sunrise.
Photo of Obelisk Guglia of the Immaculate Virgin on Piazza Gesu Nuovo in Naples (Napoli), Italy.
Photo of Boats at Marina Grande embankment in Capri Island in Tyrrhenian sea, Italy.
Photo of Stunning rooftop view of Naples from above during sunset.
Photo of Kilometers-long promenade along cascades at the Palace of Caserta, Italy.
Photo of The neighborhood called Quartieri Spagnoli in Naples, Italy. Street view of old town. Narrow street of Napoli. Bright sunny day. Gulf of Naples, blue sky, sea on background. Cacti on the terrace.
Photo of Sunset in Positano, Amalfi Coast, Salerno - Naples, Italy.
Photo of Ancient ruins of Pompei city (Scavi di Pompei), Naples, Italy.
photo of view of Colorful architecture in Naples city, Italy. Summer cityscape at sunset. Famous travel destination.
photo of view of Panoramic view of Naples city and Gulf of Naples, Italy. Blue sea and the sky with clouds at sunset. Famous travel destination.
Colosseum, Rome, Italy.
Photo of piazza de spagna in Rome, Italy.
Photo of Fountain di Trevi in Rome, Italy.
Bridge Il Tevere a Ponte Vittorio Emanuele II in Rome, Italy.
Hadrian Mausoleum, Rome, Italy.
 Vatican dome of San Pietro and Sant Angelo Bridge, over Tiber river in Rome, Italy.
panoramic view of Rome and St. Peter's Basilica, Italy.
View of Pantheon in the morning, Rome, Italy.
Rome, Italy. Stunning twilight view of Forum ancient ruins, seen from Capitoline hill with Colosseum in background.
Aerial view of forum romanum and surrounding areas of historical centre of italian capital rome.
Cozy old street in Trastevere in Rome, Italy. Trastevere is rione of Rome, on the west bank of the Tiber in Rome, Lazio, Italy. Architecture and landmark of Rome.
Aerial panorama of St. Peter's Square in Vatican with Rome in the background. Italy.
photo of view of Illuminated Fontana Di Trevi, Trevi Fountain at Dusk, Rome, Italy.
photo of view of Spanish Step, Rome, Italy.
photo of view of Museum Luasanne, Rome, Italy.
photo of view Roma Wall of Lugo, Rome, Italy.
photo of view of Roman Bridge Cordoba, Rome, Italy.
photo of view of Roman ruins in Rome, Forum, Rome, Italy.
photo of view of Roman Bridge of Cordoba, Rome, Italy.
photo of view of The Iconic, the legendary Coliseum of Rome, Italy.
photo of view of Rome, Italy: The Roman Forum, Latin: Forum Romanum, Italian: Foro Romano, Rome, Italy.
photo of view of Trevi Fountain (Fontana di Trevi) in Rome, Italy. Trevi is most famous fountain of Rome. Architecture and landmark of Rome, Postcard of Rome, Italy.
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Escape the ordinary with this exciting 8-day road trip through Italy. Explore the diverse landscapes, lively cities, and beyond. Pack your bags, hit the road, and prepare for an unforgettable journey!

This perfectly planned road trip itinerary in Italy takes you through some of the best places to see in the country. You will spend 2 nights in Brindisi, 1 night in Alberobello, 1 night in Matera, 1 night in Naples, and 2 nights in Rome. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Italy. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have got you covered.

Upon arriving in Brindisi, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Italy on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Italy. Trevi Fountain and Colosseum are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Pantheon, learn more about the unique Piazza Navona, and immerse yourself in the vibrant atmosphere of St. Peter's Basilica.

As you hit the open road and drive through Brindisi, Alberobello, Martina Franca, Conversano, Polignano a Mare, Matera, Pompei, Naples, Rome, and Orvieto, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Italy. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Italy.

Throughout your road trip in Italy, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Italy.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodation, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Italy fill up quickly, so book your spot early. Select a date and start planning your road trip in Italy today!

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Itinerary summary

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Days
Destination
Attractions
Overnight
Day
City & Overnight
Attractions
Colonne Romane
Swabian Castle of BrindisiTrulli di Alberobello PugliaBasilica di San MartinoTorre CastiglioneMonumento a Domenico ModugnoLungomare di Polignano a Mare
Casa Grotta del CasalnuovoCasa Grotta nei Sassi di MateraChurch of Saint Mary of IdrisSassi di MateraCattedrale di Maria Santissima della Bruna e Sant'EustachioPalombaro lungo
Archaeological Park of PompeiiBasilicaNaples National Archaeological Museumpiazza del Plebiscito
ColosseumRoman ForumTrevi FountainPantheonPiazza Navona
Vatican MuseumsSistine ChapelSt Peter's BasilicaPiazza di SpagnaSpanish StepsTrastevere
Well of St PatrickTorre del Moro Orvieto
Saint Pietro of Schiavoni Archeologica Area

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Day 1

Day 1

  • Brindisi - Arrival day
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  • Colonne Romane
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Say hello to Brindisi! Your exciting road trip through Italy is just about to start. Navigating the top places to see in the region is a breeze with a car. The rental vehicle of your choice will be ready for pickup upon your arrival in the city. You will stay in Brindisi for 1 night before you continue your adventure!

Brindisi is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out End Of The Via Appia Antica, or just taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

As afternoon approaches, head to your chosen hotel in Brindisi. Check-in typically starts around 2 to 4 PM at hotels in Italy. We recommend staying at a hotel in a central location for easy access to the best attractions, restaurants, and bars in the city.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Brindisi, it's often a good idea to reserve a table in advance.

Savor the flavors at Bracerie Escosazio, a top pick for dinner tonight. Alternatively, Penny beckons with its unique menu offerings. Also, consider Piadineria. With its consistent customer satisfaction, it’s an excellent option for dining in Brindisi tonight.

After savoring a delicious meal, step into the vibrant nightlife at Peddy Bar. Pasticceria. Gelateria. Happyhour. Prodotti Celiaci. Slot Machines. Scommesse, where the evening is just getting started. In the same way, Eden Cafè offers a unique charm perfect for experiencing the local bar scene in Brindisi. Altair Cafè is another top-recommended bar that is sure to get you into the mood for some dancing and celebrating.

Raise a toast to the start of your 8-day road trip in Italy!

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Day 2

Day 2

  • Brindisi
  • Alberobello
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Drive 176 km, 3 hours 34 min

  • Swabian Castle of Brindisi
  • Trulli di Alberobello Puglia
  • Basilica di San Martino
  • Torre Castiglione
  • Monumento a Domenico Modugno
  • Lungomare di Polignano a Mare
  • More

Embark on another extraordinary experience on day 2 of your road trip in Italy. Today, you will make 5 stops and experience some of the highlights of Brindisi, Alberobello, Martina Franca, Conversano, and Polignano a Mare. At the end of the day, you will enjoy the comforts of a top-rated hotel in Alberobello, which will be your home away from home for 1 night.

Get ready to discover some of the most iconic wonders in Brindisi, including a castle, a historical landmark, a church, a monument, a boardwalk and much more! Start your day at Swabian Castle Of Brindisi. This culturally significant castle is a beloved place to see in Brindisi. Then, wander over to Trulli Di Alberobello Puglia. If enchanting sites excite you, this historical landmark will be right up your alley. Nearby, you’ll also find Basilica Di San Martino. This majestic church is a favorite among visitors.

Brindisi offers plenty to explore, ensuring every moment of your visit is filled with excitement and discovery. If you're up for more, Torre Castiglione is a locally appreciated spot in the city that will captivate you with its unique charm. When you’re done at the castle, don’t forget to check out the enchanting Monumento A Domenico Modugno. Take a moment to appreciate the fascinating details of this frequently visited monument. Wrap up your self-guided tour of Brindisi's top attractions with a visit to Lungomare Di Polignano A Mare.

When you’re done exploring for the day, you’ll drive to your hotel in Alberobello. Check in and spend some time relaxing before you head out to tour the town.

As dinnertime approaches, it's time to head out for a bite to eat in Alberobello. If you are looking to dine at a popular restaurant in the town, it's often a good idea to reserve a table in advance.

Don’t miss out on dining at Ristorante "I Primi di Puglia" - Alberobello, a top-rated dining destination in Alberobello.

Raise your glass to another unforgettable day in Italy!

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Day 3

Day 3

  • Alberobello
  • Matera
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Drive 73 km, 1 hour 50 min

  • Casa Grotta del Casalnuovo
  • Casa Grotta nei Sassi di Matera
  • Church of Saint Mary of Idris
  • Sassi di Matera
  • Cattedrale di Maria Santissima della Bruna e Sant'Eustachio
  • Palombaro lungo
  • More

Dive into day 3 of your remarkable road trip in Italy. Today you will explore Matera, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Matera. You’ll stay here for 1 night.

Get ready for a day filled with family-friendly attractions, scenic views, and photo-friendly spots in the charming city of Alberobello. Your adventure starts at Casa Grotta Del Casalnuovo, a locally appreciated local hot spot. Another notable attraction to explore is Casa Grotta Nei Sassi Di Matera. This increasingly popular museum is known for its breathtaking appeal.

After soaking in the highlights of these sights, take some time to wander Alberobello's streets and immerse yourself in the local atmosphere. When you're ready to continue your sightseeing adventure, head to Church Of Saint Mary Of Idris. This enchanting church offers a fascinating experience that many visitors find memorable. Sassi Di Matera is also worth visiting, along with Cattedrale Di Maria Santissima Della Bruna E Sant'eustachio. These standout landmarks offer unique experiences that add to the day’s enjoyment. End your day at Palombaro Lungo. This curiosity-inducing cave system provides a fitting finale to your sightseeing.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Matera. Matera offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Matera. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Take some time to reflect on your day and savor another beautiful night in Italy.

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Day 4

Day 4

  • Matera
  • Naples
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Drive 251 km, 3 hours 40 min

  • Archaeological Park of Pompeii
  • Basilica
  • Naples National Archaeological Museum
  • piazza del Plebiscito
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Experience an unparalleled adventure on day 4 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 2 vibrant destinations - Pompei and Naples. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Naples. You will spend 1 night here for some well-deserved relaxation.

A blend of fun adventures, breathtaking views, and photo-friendly spots await you in Matera on today’s itinerary. First up is the notable archeological site, Archaeological Park Of Pompeii. Afterward, continue to Basilica, an archeological site every traveler should visit.

As you explore Matera’s charming streets, take in the lively atmosphere and get to know the character of the town. Next, make your way to Naples National Archaeological Museum. This notable museum is an essential stop. Following that, head to Piazza Del Plebiscito, another must-visit site that will enhance your experience.

At the end of the day, you will drive to Naples, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Naples. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Savor the flavors at L'Oca Nera Irish Pub, a top pick for dinner tonight. Alternatively, Mimì alla Ferrovia beckons with its unique menu offerings. Also, consider Spuzzulè Winebar. With its consistent customer satisfaction, it’s an excellent option for dining in Naples tonight.

After your delicious meal, get a taste of the vibrant nightlife with a visit to Happening Cocktail Bar, known for its inviting atmosphere. Shanti Art Musik Bar is another great option if you’re looking for a place to get the night started. Similarly, Gran Caffè Gambrinus provides a great setting to enjoy the night away.

Say good night to Naples and look forward to another great day of your road trip in Italy!

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Day 5

Day 5

  • Naples
  • Rome
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Drive 232 km, 3 hours 26 min

  • Colosseum
  • Roman Forum
  • Trevi Fountain
  • Pantheon
  • Piazza Navona
  • More

On day 5 of your road trip in Italy, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Rome. In the evening, you’ll end up in Rome, where you will stay for 2 nights.

Savor the day by visiting some of the best places to see in Naples, including an archeological site, a monument, and a public square. Start your adventure at Colosseum. This globally renowned archeological site is a must-visit for travelers looking for a unique holiday experience. Make your way to Roman Forum located in Naples for another exciting encounter.

Next, immerse yourself in the setting of Trevi Fountain. Its symbolic features will captivate you. After the monument, continue your tour of the city with a visit to Pantheon. Visitors usually appreciate the heritage-rich features of this monument. Next up is Piazza Navona, a highly recommended public square.

When you’re done exploring for the day, you’ll drive to your hotel in Rome. Check in and spend some time relaxing before you head out to tour the city.

After a day of adventure, treat yourself to an exquisite dinner at one of Rome's best restaurants.

Treat yourself to a delicious dinner at La Bottega Roma, an excellent option for tonight's dining. Looking for something different? Pasta In Corso offers a tantalizing alternative with its diverse menu. And don’t miss Trattoria Vecchia Roma. With its reputation for pleasing customers, it’s a fantastic choice for tonight in Rome.

If you’re not ready to end the night just yet, La Botticella Of Poggi Giovanni offers a perfect venue to relax and savor a drink. Similarly, Almalu Trastevere is well-suited for those looking to unwind in a social setting. Bar Viminale Di Pepi Maurilio is another excellent spot to enjoy a nightcap after a delightful meal.

Raise your glass and celebrate another amazing day of your road trip in Italy!

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Day 6

Day 6

  • Rome
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Drive 16 km, 1 hour 4 min

  • Vatican Museums
  • Sistine Chapel
  • St Peter's Basilica
  • Piazza di Spagna
  • Spanish Steps
  • Trastevere
  • More

On day 6 of your road trip in Italy, you’ll start and end your day in Rome, but spend the day exploring what’s beyond the city. Since you will return to Rome for 1 night more, there’s no need to rush. Experience Vatican City and Rome to the fullest today with this curated day itinerary!

Make sure to visit Trastevere, a popular neighborhood in Vatican City. Spend some time wandering around the area and soak in its distinctive charm. You’ll also discover that several of the city’s must-see attractions are just around the corner.

Start by visiting Vatican Museums, a prime spot to begin your journey.

We also recommend visiting Piazza Di Spagna, a timeless public square. Nearby, you'll also find Spanish Steps, ready to add charm to your journey.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Rome.

As dinnertime approaches, it's time to head out for a bite to eat in Rome. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Dine in style at RomAntica, a top recommendation for dinner tonight. Or, for a change of pace, Coso Ristorante boasts a menu that's sure to impress. Also, be sure to check out DEROMA - Farine Romane. Known as a local hotspot, it’s a great choice for tonight in Rome.

Extend your evening after a delightful meal by visiting Sant' Eustachio Caffè, which offers the perfect atmosphere for a night out. Moreover, Yellowsquare Rome is another popular option for a drink or two. Likewise, Caffè Portofino also provides a great ambiance for reminiscing about the day and raising a toast to your vacation.

Relax and recharge in preparation for another adventurous day in Italy!

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Day 7

Day 7

  • Rome
  • Brindisi
  • More

Drive 791 km, 8 hours 27 min

  • Well of St Patrick
  • Torre del Moro Orvieto
  • More

On day 7 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 1 destination, Orvieto. When you’re not sightseeing, take time to relax at your selected hotel in Brindisi, where you’ll be staying for 1 night.

Enjoy the perfect balance of relaxation and exploration in Rome today. One of the most captivating attractions included on the itinerary is Well Of St. Patrick. This standout monument will help you start your sightseeing on top. Then, take a leisurely stroll to Torre Del Moro Orvieto and learn what makes this awe-inspiring monument unique.

Throughout the day, make sure to take breaks to appreciate the surroundings.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Brindisi. Brindisi offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

As you explore more of Brindisi, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Make sure to reserve a table at Betty - Gelateria Cafe Ristorante Pizzeria a Brindisi, an iconic dining spot in Brindisi. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Bento, a popular restaurant in Brindisi. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Cozza Nera, a hidden gem nestled in Brindisi. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in in Italy.

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Day 8

Day 8

  • Brindisi - Departure day
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  • Saint Pietro of Schiavoni Archeologica Area
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Day 8 of your road trip in Italy is your departure day. This is your chance to catch a last glimpse of Brindisi before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, begin at Saint Pietro Of Schiavoni Archeologica Area. This up-and-coming archeological site is a popular place to see in the city.

On your last day in Italy, take time to indulge in shopping at Brindisi’s popular marketplace. Look for keepsakes or souvenirs to remind you of your trip.

Before you conclude your road trip in Italy, drop by another restaurant for a last chance at a memorable dining experience in Brindisi.

If you're in the mood for something new, try Pizzeria La Nassa, another premier location with a delectable menu.

You’ll then say farewell to Brindisi. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Italy!

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