One-Week Italy Self-Drive Road Trip With Itinerary from Pescara traveling west to Rome, Florence, and Santa Maria degli Angeli

Perfect travel plans
Everything included
Fully customizable

Description

Included

Flights
Select dates
Hotel
Select dates
Car rental
Select dates
Tours & tickets
Select dates
Travel plan
From A to Z
Travel agent
24/7 fast service

Description

Escape the ordinary with this exciting 8-day road trip through Italy. Explore the diverse landscapes, lively cities, and beyond. Pack your bags, hit the road, and prepare for an unforgettable journey!

This perfectly planned road trip itinerary in Italy takes you through some of the best places to see in the country. You will spend 2 nights in Pescara, 2 nights in Rome, 2 nights in Florence, and 1 night in Santa Maria degli Angeli. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Italy. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have got you covered.

Upon arriving in Pescara, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Italy on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Italy. Trevi Fountain and Colosseum are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Pantheon, learn more about the unique Piazza Navona, and immerse yourself in the vibrant atmosphere of St. Peter's Basilica.

As you hit the open road and drive through Pescara, Rome, Florence, Pisa, Siena, Santa Maria degli Angeli, and Gubbio, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Italy. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Italy.

Throughout your road trip in Italy, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Italy.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodation, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Italy fill up quickly, so book your spot early. Select a date and start planning your road trip in Italy today!

Read more

Travel details

Set your travel details to find the best price

Flights

Round trip
Round trip
Travel dates

Travelers

Rooms

Flights

Compare and choose from the best flights to Pescara

Car

Choose from the best car rental deals or see all options

Driver’s age is 30 - 65
I live in

Itinerary summary

See a summary of the itinerary that you can fully customize

Days
Destination
Attractions
Overnight
Day
City & Overnight
Attractions
Locomotiva FS 740351
ColosseumRoman ForumPantheonSpanish StepsPiazza di SpagnaTrevi Fountain
Vatican MuseumsSistine ChapelSt Peter's BasilicaPiazza NavonaTrastevereVia del Corso
Basilica of Santa Croce in FlorenceUffizi GalleryPonte VecchioPiazza della RepubblicaCathedral of Santa Maria del Fiorepiazza della Signoria
Piazza del Duomo, PisaLeaning Tower of PisaThe Boboli Gardenspiazzale MichelangeloOltrarno
Fortezza MediceaSiena Cathedralpiazza del CampoPorta PispiniBasilica of San Francesco d'AssisiPiazza del Comune
Basilica of Sant'Ubaldo, GubbioFunivia Colle ElettoPalazzo dei ConsoliChiesa di San FrancescoGola Del Bottaccione Gubbio
Parrocchia Spirito Santo

Personalize your itinerary

Customize tours under each day and destination

Day 1

Day 1

  • Pescara - Arrival day
  • More
  • Locomotiva FS 740351
  • More

Welcome to Pescara, the perfect starting point for your road trip in Italy! Pick up your rental car and let the adventure begin. You will spend 1 night immersing yourself in Pescara's charm before embarking on the next leg of your journey.

Pescara is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Locomotiva Fs 740.351, or just taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

Find your way to your hotel in Pescara. We recommend choosing a hotel in a central location for easy exploring. Check-in typically starts between 2 and 4 PM at hotels in Italy. Settle in and make plans for the evening.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Pescara, it's often a good idea to reserve a table in advance.

Make sure to reserve a table at Taverna 58, an iconic dining spot in Pescara. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Ristorante Carlo Ferraioli, a popular restaurant in Pescara. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Sesamo Nero, a hidden gem nestled in Pescara. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

To truly maximize your evening out, consider visiting Posa Caffè Pescara after dinner. This bar is known for offering some of the best drinks and vibes in the city. Alternatively, head to Bar Mixer, another bar with an inviting ambiance. Similarly, Temple Bar Irish Pub also offers a great atmosphere, ensuring a night filled with enjoyment and relaxation.

Raise a toast to the start of your 8-day road trip in Italy!

Read more
Day 2

Day 2

  • Pescara
  • Rome
  • More

Drive 214 km, 3 hours 27 min

  • Colosseum
  • Roman Forum
  • Pantheon
  • Spanish Steps
  • Piazza di Spagna
  • Trevi Fountain
  • More

Embark on another extraordinary experience on day 2 of your road trip in Italy. Today, you will make 1 stop and experience some of the highlights of Rome. At the end of the day, you will enjoy the comforts of a top-rated hotel in Rome, which will be your home away from home for 2 nights.

Get ready for a day filled with family-friendly attractions, breathtaking views, and photo-friendly spots in the charming city of Pescara. Your adventure starts at Colosseum, a world-famous local hot spot. Another notable attraction to explore is Roman Forum. This world-famous archeological site is known for its breathtaking appeal.

After soaking in the highlights of these sights, take some time to wander Pescara's streets and immerse yourself in the local atmosphere. When you're ready to continue your sightseeing adventure, head to Pantheon. This photogenic monument offers a fascinating experience that many visitors find memorable. Spanish Steps is also worth visiting, along with Piazza Di Spagna. These standout landmarks offer unique experiences that add to the day’s enjoyment. End your day at Trevi Fountain. This world-famous monument provides a fitting finale to your sightseeing.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Rome. Rome offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

As you explore more of Rome, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Treat yourself to a delicious dinner at La Bottega Roma, an excellent option for tonight's dining. Looking for something different? Pasta In Corso offers a tantalizing alternative with its diverse menu. And don’t miss Trattoria Vecchia Roma. With its reputation for pleasing customers, it’s a fantastic choice for tonight in Rome.

After your meal, keep the night alive at a bar like La Botticella Of Poggi Giovanni, known for its lively atmosphere. Almalu Trastevere is another top recommendation that provides the perfect setting with well-crafted drinks and a welcoming ambiance. Similarly, Bar Viminale Di Pepi Maurilio offers an excellent atmosphere for those looking to amp up the evening.

Relax and recharge in preparation for another adventurous day in Italy!

Read more
Day 3

Day 3

  • Rome
  • More

Drive 8 km, 55 min

  • Vatican Museums
  • Sistine Chapel
  • St Peter's Basilica
  • Piazza Navona
  • Trastevere
  • Via del Corso
  • More

At the end of the day, you'll drive back to Rome, where you'll stay for 1 night more.

Make sure to visit Trastevere, a popular neighborhood in Vatican City. Spend some time wandering around the area and soak in its distinctive charm. You’ll also discover that several of the city’s must-see attractions are just around the corner. You can also explore Via del Corso today, a street that’s well worth a visit.

Prepare for a day full of fun adventures, romantic experiences, and scenic views. When you’re ready, kick off your sightseeing adventure at Vatican Museums. This timeless art museum is a must-visit for anyone seeking a unique vacation experience. Another sight you shouldn’t miss is Sistine Chapel, one of the city’s best highlights.

Next, check out St. Peter's Basilica, one of the most world-famous places to see in Rome. This major basilica is a favorite among locals and travelers alike. Enjoy some downtime and refreshments before continuing to your next stop, Piazza Navona. Wander around and soak in the enchanting atmosphere this public square offers.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Rome.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Rome. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Dine in style at RomAntica, a top recommendation for dinner tonight. Or, for a change of pace, Coso Ristorante boasts a menu that's sure to impress. Also, be sure to check out DEROMA - Farine Romane. Known as a local hotspot, it’s a great choice for tonight in Rome.

After your meal, keep the night alive at a bar like Sant' Eustachio Caffè, known for its lively atmosphere. Yellowsquare Rome is another top recommendation that provides the perfect setting with well-crafted drinks and a welcoming ambiance. Similarly, Caffè Portofino offers an excellent atmosphere for those looking to amp up the evening.

Raise your glass and celebrate another amazing day of your road trip in Italy!

Read more
Day 4

Day 4

  • Rome
  • Florence
  • More

Drive 276 km, 3 hours 31 min

  • Basilica of Santa Croce in Florence
  • Uffizi Gallery
  • Ponte Vecchio
  • Piazza della Repubblica
  • Cathedral of Santa Maria del Fiore
  • piazza della Signoria
  • More

Experience an unparalleled adventure on day 4 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 1 vibrant destinations - Florence. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Florence. You will spend 2 nights here for some well-deserved relaxation.

Enjoy the perfect balance of relaxation and exploration in Rome today. One of the most interesting attractions included on the itinerary is Basilica Of Santa Croce In Florence. This monumental church will help you start your sightseeing on top. Then, take a leisurely stroll to Uffizi Gallery and learn what makes this romantic art gallery unique.

Throughout the day, make sure to take breaks to appreciate the surroundings. Next up, visit the globally renowned Ponte Vecchio. After exploring the historical landmark, head to Piazza Della Repubblica. This popular public square is a highlight in Rome. As your day continues, stop by Cathedral Of Santa Maria Del Fiore, known for its UNESCO world heritage-designated features. Lastly, don’t forget to check out the widely recognized Piazza Della Signoria. Enjoy exploring this incredible public square at your own pace.

When you’re done exploring for the day, you’ll drive to your hotel in Florence. Check in and spend some time relaxing before you head out to tour the city.

After a day of adventure, treat yourself to an exquisite dinner at one of Florence's best restaurants.

Make sure to reserve a table at Ristorante Oliviero 1962, an iconic dining spot in Florence. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Di Poneta Novoli, a popular restaurant in Florence. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Caffe San Firenze, a hidden gem nestled in Florence. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Continue the enjoyment post-dinner at Manifattura, a cherished local gathering spot renowned for its welcoming atmosphere. Similarly, Se·sto On Arno Rooftop Bar offers a vibrant space for indulging in well-crafted drinks and engaging conversation. You may also want to check out Il Vinile. This bar is a favorite among both locals and visitors looking for a delightful evening out filled with laughter and fun.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in in Italy.

Read more
Day 5

Day 5

  • Florence
  • More

Drive 177 km, 2 hours 54 min

  • Piazza del Duomo, Pisa
  • Leaning Tower of Pisa
  • The Boboli Gardens
  • piazzale Michelangelo
  • Oltrarno
  • More

On day 5 of your road trip, you’ll start and end your day in Florence, where you'll stay for 1 night more.

A visit to Oltrarno in Pisa is a must on the agenda today. This neighborhood is full of hidden gems and character, perfect for a leisurely stroll. Plus, you’ll be close to some of the city’s most famous sights.

Today's adventure in Florence promises more breathtaking discoveries and enriching experiences! Begin at Piazza Del Duomo, Pisa. This UNESCO world heritage-listed public square is a highlight of any visit in the city. Then, enjoy Leaning Tower Of Pisa, another breathtaking attraction that never fails to captivate visitors. Next, head over to The Boboli Gardens, one of the city’s most notable attractions, known for its history-steeped features.

If you’re looking for more, spend time soaking in the atmosphere of Piazzale Michelangelo. This romantic observation deck is frequented by locals and tourists alike. To complete your memorable day, make sure to take a stroll around the area.

When you’re done exploring for the day, you’ll return to Florence and your accommodation.

Indulge in a memorable dining experience at one of Florence's most popular restaurants, and connect with friendly locals for an authentic adventure.

Savor the flavors at Ditta Artigianale, a top pick for dinner tonight. Alternatively, Trattoria Da Burde beckons with its unique menu offerings. Also, consider Casa Toscana. With its consistent customer satisfaction, it’s an excellent option for dining in Florence tonight.

Following your dinner, dive into the local bar culture at Bar 50 Rosso. Enjoy this evening's relaxed ambiance with delightful drinks. Alternatively, go to Bitter Bar, the perfect place for those looking to experience the best of the nightlife. Similarly, Archea Brewery provides excellent drinks and a great atmosphere, ensuring a memorable night out.

Head back to your accommodation in Florence and get some rest in preparation for another magical day of your road trip in Italy!

Read more
Day 6

Day 6

  • Florence
  • Assisi
  • More

Drive 200 km, 3 hours 36 min

  • Fortezza Medicea
  • Siena Cathedral
  • piazza del Campo
  • Porta Pispini
  • Basilica of San Francesco d'Assisi
  • Piazza del Comune
  • More

Dive into day 6 of your remarkable road trip in Italy. Today you will explore Siena and Santa Maria degli Angeli, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Santa Maria degli Angeli. You’ll stay here for 1 night.

Florence is brimming with adventures. Today’s wonderful stops include a monument, a church, a public square, a historical landmark and much more! Begin your sightseeing adventure at the curiosity-inducing Fortezza Medicea (siena) and allow yourself time to explore. Just a short distance away you'll find your next stop, Siena Cathedral, an enchanting church that draws visitors from far and near.

Continue your journey to Piazza Del Campo, one of the city’s most impressive spots that you shouldn’t miss. Another great site to visit is the worthwhile Porta Pispini. When you're finished at the historical landmark, Basilica Of San Francesco D'assisi awaits your visit. This church is a breathtaking highlight on today's itinerary. Last up is a public square - the often recommended Piazza Del Comune.

At the end of the day, you will drive to Santa Maria degli Angeli, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Santa Maria degli Angeli. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

After savoring a delicious meal, step into the vibrant nightlife at Bibenda Assisi Wine Tasting & Gourmet Food, Olive Oil And Chocolate Tastings, where the evening is just getting started.

Head back to your accommodation in Santa Maria degli Angeli and get some rest in preparation for another magical day of your road trip in Italy!

Read more
Day 7

Day 7

  • Assisi
  • Pescara
  • More

Drive 318 km, 5 hours 19 min

  • Basilica of Sant'Ubaldo, Gubbio
  • Funivia Colle Eletto
  • Palazzo dei Consoli
  • Chiesa di San Francesco
  • Gola Del Bottaccione Gubbio
  • More

On day 7 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 1 destination, Gubbio. When you’re not sightseeing, take time to relax at your selected hotel in Pescara, where you’ll be staying for 1 night.

Santa Maria degli Angeli is home to plenty of attractions that offer fun adventures, breathtaking views, and photo-friendly spots! Start at Basilica Of Sant'ubaldo, Gubbio, a locally appreciated church that is worthwhile a visit in the town. Nearby, you’ll find Funivia Colle Eletto, enchanting visitors with its eye-catching appeal. Continue your exploration at Palazzo Dei Consoli. This museum is one of the town’s most beloved spots.

Enjoy the freedom of exploring Santa Maria degli Angeli at your own pace and find hidden gems along the way. If you want to see more picture-perfect spots, make sure to visit Chiesa Di San Francesco. After exploring the church, head to the up-and-coming Gola Del Bottaccione.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Pescara. Pescara offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

As dinnertime approaches, it's time to head out for a bite to eat in Pescara. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Savor the flavors at Ciacco, a top pick for dinner tonight. Alternatively, Bar Sara beckons with its unique menu offerings. Also, consider Ristorante Franco. With its consistent customer satisfaction, it’s an excellent option for dining in Pescara tonight.

To truly maximize your evening out, consider visiting Bar Napoli after dinner. This bar is known for offering some of the best drinks and vibes in the city. Alternatively, head to Bar Supermarket, another bar with an inviting ambiance. Similarly, Post Bar also offers a great atmosphere, ensuring a night filled with enjoyment and relaxation.

Take some time to reflect on your day and savor another beautiful night in Italy.

Read more
Day 8

Day 8

  • Pescara - Departure day
  • More
  • Parrocchia Spirito Santo
  • More

Day 8 of your road trip in Italy is your departure day. This is your chance to catch a last glimpse of Pescara before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, begin at Parrocchia Spirito Santo. This up-and-coming church is a popular place to see in the city.

On your last day in Italy, take time to indulge in shopping at Pescara’s popular marketplace, Centro Commerciale Pescara Porta Nuova. Look for keepsakes or souvenirs to remind you of your trip.

Before you conclude your road trip in Italy, drop by another restaurant for a last chance at a memorable dining experience in Pescara.

If you're in the mood to try something new, consider La Taverna Antica, another top spot with a mouthwatering menu.

You’ll then say farewell to Pescara. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Italy!

Read more

Similar travel packages

Discover other popular vacations in Italy

Link to appstore phone
Install Europe’s biggest travel app

Download Europe’s biggest travel marketplace to your phone to manage your entire trip in one place

Scan this QR code with your phone camera and press the link that appears to add Europe’s biggest travel marketplace into your pocket. Enter your phone number or email address to receive an SMS or email with the download link.