One-Week Italy Self-Drive Road Trip With Itinerary from Pisa traveling west to Genoa and Milan

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Explore the best of Italy on a 8-day road trip! Uncover hidden gems and experience the rich culture firsthand as you journey through Pisa, Tirrenia, Corniglia, Genoa, Milan, and Priorato. This road trip itinerary in Italy seamlessly combines exploration with relaxation.

This perfectly planned road trip itinerary in Italy takes you through some of the best places to see in the country. You will spend 3 nights in Pisa, 1 night in Genoa, and 3 nights in Milan. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Italy. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have got you covered.

Upon arriving in Pisa, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Italy on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Italy. Duomo Di Milano Museum and Leaning Tower Of Pisa are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Piazza Del Duomo, Pisa, learn more about the unique Galleria Vittorio Emanuele Ii, and immerse yourself in the vibrant atmosphere of Parco Sempione.

As you hit the open road and drive through Pisa, Tirrenia, Corniglia, Genoa, Milan, and Priorato, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Italy. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Italy.

Throughout your road trip in Italy, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Italy.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodation, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Italy fill up quickly, so book your spot early. Select a date and start planning your road trip in Italy today!

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Driver’s age is 30 - 65
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Itinerary summary

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Days
Destination
Attractions
Overnight
Day
City & Overnight
Attractions
Knights' Square
Leaning Tower of PisaPiazza del Duomo, PisaPisa CathedralBagno degli AmericaniParco Regionale Migliarino, San Rossore, Massaciuccoli
Palazzo BluSanta Maria della SpinaCittadella NuovaCinque Terre National Park
piazza De FerrariGenoa CathedralAquarium of Genoaporto antico
Leonardo da Vinci Museum of Science and TechnologySanta Maria delle Grazie ChurchCastello SforzescoSempione ParkArch of Peace
Piazza Gae AulentiPinacoteca di BreraBasilica di Sant'AmbrogioMUDEC - Museum of Cultures
La ScalaGalleria Vittorio Emanuele IIDuomo di MilanoRocca Sanvitale
“Tuttomondo” (Keith Haring)

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Day 1

Day 1

  • Pisa - Arrival day
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  • Knights' Square
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Your road trip adventure in Italy begins as soon as you reach Pisa and pick up your car. You’ll stay in Pisa for 2 nights and explore the best things to see and do, sample the local cuisine, and choose from a curated selection of the best hotels and places to stay in the city.

Pisa is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Knights' Square, or just taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

As afternoon approaches, head to your chosen hotel in Pisa. Check-in typically starts around 2 to 4 PM at hotels in Italy. We recommend staying at a hotel in a central location for easy access to the best attractions, restaurants, and bars in the city.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Pisa, it's often a good idea to reserve a table in advance.

Don’t miss out on dining at Anima di Grano Pizzeria Napoletana Pisa Italy, a top-rated dining destination in Pisa. If you're in the mood to try something new, consider il Mercante, another top spot with a mouthwatering menu. You might also want to secure a reservation at La Ghiotteria. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Pisa this evening.

Continue your evening by exploring the vibrant nightlife scene at Jeffer Cocktails & Friends, a prime destination for a thrilling night out. Also, don’t forget to check out Le Parisien Wine Bar, a bar that offers unique local touches. Likewise, Las Volta Cocktailbar provides an excellent alternative for a fun evening.

Raise a toast to the start of your 8-day road trip in Italy!

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Day 2

Day 2

  • Pisa
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Drive 44 km, 1 hour 20 min

  • Leaning Tower of Pisa
  • Piazza del Duomo, Pisa
  • Pisa Cathedral
  • Bagno degli Americani
  • Parco Regionale Migliarino, San Rossore, Massaciuccoli
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Wake up to day 2 of your extraordinary road trip in Italy. With 1 night left in Pisa, we encourage you to seize the day and discover the unexplored beauty of the city’s surroundings!

Begin your adventure at Leaning Tower Of Pisa. This is an iconic monument you should not miss. Another must-see is Piazza Del Duomo, Pisa, an iconic public square in Pisa.

When you’re ready for the next sight, head to Pisa Cathedral. From there, take a leisurely stroll to Bagno Degli Americani, another of the city’s up-and-coming attractions. We recommend continuing your self-guided tour at Parco Regionale Migliarino, San Rossore, Massaciuccoli, a romantic place of interest in the city.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Pisa.

After a day of adventure, treat yourself to an exquisite dinner at one of Pisa's best restaurants.

Enjoy a delicious meal at Ristorante Capodimonte Pisa, a highly-rated dining destination in Pisa. If you're eager to try something different, consider La Locanda Dei Pisani Doc Pisa, another top spot with a tantalizing menu. You might also want to secure a reservation at Baribaldi Pisa. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Pisa this evening.

After your delicious meal, get a taste of the vibrant nightlife with a visit to Bar Mocambo, known for its inviting atmosphere. Tree is another great option if you’re looking for a place to get the night started. Similarly, Chupiteria provides a great setting to enjoy the night away.

Say good night to Pisa and look forward to another great day of your road trip in Italy!

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Day 3

Day 3

  • Pisa
  • Genoa
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Drive 212 km, 3 hours 35 min

  • Palazzo Blu
  • Santa Maria della Spina
  • Cittadella Nuova
  • Cinque Terre National Park
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Experience an unparalleled adventure on day 3 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 2 vibrant destinations - Pisa and Corniglia. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Genoa. You will spend 1 night here for some well-deserved relaxation.

Today’s well-planned self-sightseeing route offers several fun adventures, photo-friendly spots, and history-rich sites. Whether you decide to explore Pisa on foot, use public transport, or join a guided tour, there are a few attractions you don’t want to miss. Palazzo Blu is the first of them. Spend some time admiring this history-steeped art gallery before continuing your journey. Santa Maria Della Spina is your next stop. This increasingly popular church is one of the best-rated sights in Pisa.

Consider grabbing some lunch or a light snack to keep your energy going. Beyond the above-mentioned attractions, today is also the perfect time to visit Cittadella Nuova. This romantic park is a sight to behold. To round off your sightseeing experience, visit Cinque Terre National Park.

When you’re done exploring for the day, you’ll drive to your hotel in Genoa. Check in and spend some time relaxing before you head out to tour the city.

After a day of adventure, treat yourself to an exquisite dinner at one of Genoa's best restaurants.

Experience a harmony of flavors at San Giorgio in Genoa by securing a reservation in advance. Known for its 1-star Michelin status, San Giorgio offers a delightful variety of dishes highlighting its delicious modern and ligurian menu. If you're seeking an alternative culinary experience, be sure to explore The Cook, a highly recommended restaurant known for its enticing modern cuisine. This popular 1-star Michelin-awarded venue consistently exceeds expectations, ensuring a memorable holiday experience. Ready for another culinary adventure? Indulge your senses at Il Marin, a highly acclaimed restaurant celebrated for its exceptional seafood and contemporary menu.

Following your dinner, dive into the local bar culture at Scurreria Beer & Bagel. Enjoy this evening's relaxed ambiance with delightful drinks. Alternatively, go to La Lepre, the perfect place for those looking to experience the best of the nightlife. Similarly, Bar Pisacane Iii provides excellent drinks and a great atmosphere, ensuring a memorable night out.

Savor another day of unforgettable experiences in Italy!

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Day 4

Day 4

  • Genoa
  • Milan
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Drive 144 km, 2 hours 17 min

  • piazza De Ferrari
  • Genoa Cathedral
  • Aquarium of Genoa
  • porto antico
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Dive into day 4 of your remarkable road trip in Italy. Today you will explore Genoa, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Milan. You’ll stay here for 3 nights.

Prepare for a day full of fun adventures, romantic experiences, and scenic views. When you’re ready, kick off your sightseeing adventure at Piazza De Ferrari. This notable public square is a must-visit for anyone seeking a unique vacation experience. Another sight you shouldn’t miss is Genoa Cathedral, one of the city’s best highlights.

Next, check out Aquarium Of Genoa, one of the most top-rated places to see in Genoa. This aquarium is a favorite among locals and travelers alike. Enjoy some downtime and refreshments before continuing to your next stop, Porto Antico. Wander around and soak in the history-steeped atmosphere this public square offers.

At the end of the day, you will drive to Milan, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As dinnertime approaches, it's time to head out for a bite to eat in Milan. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Enjoy an outstanding dining experience at Enrico Bartolini al Mudec, a 3-star Michelin restaurant offering an exceptional creative menu. Alternatively, if you're in the mood for something different, consider the nearby 2-star Michelin-awardee, Seta by Antonio Guida, known for its delicious international and contemporary cuisine. Another highly-recommended place to eat in Milan is Il Luogo Aimo e Nadia, a renowned restaurant with a 1-star Guide Michelin recognition and a delicious italian contemporary and modern menu.

To truly maximize your evening out, consider visiting Nottingham Forest after dinner. This bar is known for offering some of the best drinks and vibes in the city. Alternatively, head to Armani/bamboo Bar, another bar with an inviting ambiance. Similarly, Mag Cafe also offers a great atmosphere, ensuring a night filled with enjoyment and relaxation.

Head back to your accommodation in Milan and get some rest in preparation for another magical day of your road trip in Italy!

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Day 5

Day 5

  • Milan
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Drive 9 km, 1 hour

  • Leonardo da Vinci Museum of Science and Technology
  • Santa Maria delle Grazie Church
  • Castello Sforzesco
  • Sempione Park
  • Arch of Peace
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Day 5 offers a multitude of experiences. You will stay in Milan for 2 nights more, offering you enough time to explore at a relaxed pace.

Whether you prefer a leisurely exploration or a more fast-paced adventure, this itinerary in Milan allows for both. Start by heading to Museo Della Scienza E Della Tecnologia "leonardo Da Vinci". This popular museum provides an insightful glimpse into the city's identity. Next, discover Santa Maria Delle Grazie Church, an UNESCO world heritage-designated church, promising a delightful encounter.

Continue your sightseeing with a visit to Sforzesco Castle Art Library, a spectacular castle. When you’re done, don’t forget to make a stop at the top-rated Parco Sempione. Round off your day at Arch Of Peace, another gem in Milan with picture-perfect features to discover.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

After a day of adventure, treat yourself to an exquisite dinner at one of Milan's best restaurants.

Enjoy a delicious meal at Dessert Bar Milano, a top-rated dining destination in Milan. If you're in the mood to try something new, consider Radisson Blu Hotel Milan, another top spot with a mouthwatering menu. You might also want to secure a reservation at Ristorante Qui Si Mangia. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Milan this evening.

Extend your evening after a delightful meal by visiting Kilburn Cocktail Bar Milano, which offers the perfect atmosphere for a night out. Moreover, Bar Frida is another popular option for a drink or two. Likewise, The Friends Pub Milano also provides a great ambiance for reminiscing about the day and raising a toast to your vacation.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in in Italy.

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Day 6

Day 6

  • Milan
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Drive 15 km, 1 hour 16 min

  • Piazza Gae Aulenti
  • Pinacoteca di Brera
  • Basilica di Sant'Ambrogio
  • MUDEC - Museum of Cultures
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On day 6 of your road trip, you will have an entire day to explore Milan. You’ll stay in Milan for 1 night and discover all the best things to see and do in the area.

Get ready to discover some of the most iconic wonders in Milan, including a public square, an art gallery, a church, a museum and much more! Start your day at Piazza Gae Aulenti. This picture-perfect public square is a popular place to see in Milan. Then, wander over to Pinacoteca Di Brera. If historic sites excite you, this art gallery will be right up your alley. Nearby, you’ll also find Basilica Di Sant'ambrogio. This culturally significant church is a favorite among visitors.

Milan offers plenty to explore, ensuring every moment of your visit is filled with excitement and discovery. If you're up for more, Mudec - Museum Of Cultures is a popular spot in the city that will captivate you with its unique charm.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

As you explore more of Milan, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Don’t miss out on dining at Bice Restaurant, a top-rated dining destination in Milan. If you're in the mood to try something new, consider Alto Ristorante, another top spot with a mouthwatering menu. You might also want to secure a reservation at Nero 9. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Milan this evening.

Round off your dining experience by visiting Bhangrabar, a prime location for a drink. Alternatively, explore the distinctive characteristics of Rufus Cocktail Bar, a bar catering to every mood and preference. Ostello Bello Grande likewise offers a unique atmosphere, perfect for a memorable night out.

Savor another day of unforgettable experiences in Italy!

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Day 7

Day 7

  • Milan
  • Pisa
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Drive 289 km, 3 hours 45 min

  • La Scala
  • Galleria Vittorio Emanuele II
  • Duomo di Milano
  • Rocca Sanvitale
  • More

On day 7 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 2 destinations, Milan and Priorato. When you’re not sightseeing, take time to relax at your selected hotel in Pisa, where you’ll be staying for 1 night.

Today’s route brings family-friendly attractions, romantic experiences, and photo-friendly spots. The first attraction of today is La Scala. This well-known opera house is a romantic place to see in Milan. Continue your discovery at Galleria Vittorio Emanuele Ii, a visually striking shopping mall with stories to tell.

As you stroll around Milan, take in the distinct atmosphere and learn what makes this city so unique. Maximize your sightseeing with a visit to Duomo Di Milano Museum. This world-famous church offers a romantic encounter with Milan. Next, make your way to Rocca Sanvitale to add another highlight to your day. Whether you decide to get entrance tickets for all attractions or you prefer admiring from a distance, amazing experiences await on this day in Milan.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Pisa. Pisa offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Pisa. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Enjoy a lovely meal at Restaurant -Pizzeria Il Mio Capriccio, a top-rated place to have dinner tonight. Alternatively, if your taste buds call for something different, Ristorante alle Bandierine is another top choice with a popular menu. You could also check for a table at Barrique Cocktail And Bistrot. As an establishment that gains consistently high praises from customers, it’s an ideal choice in Pisa tonight.

Keep the evening going at Bar Livorno, a great choice for enjoying the after-dinner hours with a drink.

As the sun sets on another day of adventure, rest up and recharge for the next leg of your road trip in Italy.

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Day 8

Day 8

  • Pisa - Departure day
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  • “Tuttomondo” (Keith Haring)
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Day 8 of your road trip in Italy is your departure day. This is your chance to catch a last glimpse of Pisa before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, begin at “tuttomondo” (keith Haring). This frequently visited art installation is a popular place to see in the city.

Maximize your last day in Italy and go on a shopping spree in Pisa’s shopping center. Browse for souvenirs to remind you of your wonderful journey in Italy.

Before you conclude your road trip in Italy, drop by another restaurant for a last chance at a memorable dining experience in Pisa.

Enjoy a lovely meal at Anita Osteria, a top-rated place to have dinner tonight. Alternatively, if your taste buds call for something different, La corte di San Leonardo is another top choice with a popular menu.

You’ll then say farewell to Pisa. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Italy!

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