11-Day Italy Self-Drive Road Trip With Itinerary from Perugia traveling west to Rome, Siena, and Arezzo
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Explore the best of Italy on a 11-day road trip! Uncover hidden gems and experience the rich culture firsthand as you journey through Perugia, Rome, Siena, and Arezzo. This road trip itinerary in Italy seamlessly combines exploration with relaxation.
This perfectly planned road trip itinerary in Italy takes you through some of the best places to see in the country. You will spend 2 nights in Perugia, 4 nights in Rome, 2 nights in Siena, and 2 nights in Arezzo. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!
With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Italy. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have got you covered.
Upon arriving in Perugia, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Italy on your own terms.
An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Italy. Trevi Fountain and Colosseum are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Pantheon, learn more about the unique Piazza Navona, and immerse yourself in the vibrant atmosphere of St. Peter's Basilica.
As you hit the open road and drive through Perugia, Rome, Siena, and Arezzo, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Italy. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Italy.
Throughout your road trip in Italy, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Italy.
This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodation, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.
The best services in Italy fill up quickly, so book your spot early. Select a date and start planning your road trip in Italy today!
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Day 1
- Perugia - Arrival day
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- Piazza IV Novembre
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Your road trip adventure in Italy begins as soon as you reach Perugia and pick up your car. You’ll stay in Perugia for 1 night and explore the best things to see and do, sample the local cuisine, and choose from a curated selection of the best hotels and places to stay in the city.
Perugia is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Piazza Iv Novembre, or just taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.
Find your way to your hotel in Perugia. We recommend choosing a hotel in a central location for easy exploring. Check-in typically starts between 2 and 4 PM at hotels in Italy. Settle in and make plans for the evening.
As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Perugia, it's often a good idea to reserve a table in advance.
Make sure to reserve a table at Ristorante Settimo Sigillo, an iconic dining spot in Perugia. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Caffè Baglioni, a popular restaurant in Perugia. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Bar Pellas, a hidden gem nestled in Perugia. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.
After enjoying a fulfilling meal, continue your evening at Tommi Bar, ideal for those looking to unwind with a drink in a comfortable setting. Alternatively, Valentina offers a welcoming atmosphere for easing into the nightlife. Similarly, Caffe Dal Perugino provides an excellent environment for a relaxed and enjoyable evening.
Raise a toast to the start of your 11-day road trip in Italy!
Day 2
- Perugia
- Rome
- More
Drive 184 km, 2 hours 33 min
- Carducci Gardens
- Porta Marzia
- Rocca Paolina
- More
Dive into day 2 of your remarkable road trip in Italy. Today you will explore Perugia, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Rome. You’ll stay here for 4 nights.
Today’s agenda in Perugia includes a park, a monument, and a historical landmark. Carducci Gardens is must-visit park and a great starting point for the day. Next, continue your journey to Porta Marzia, a frequently visited monument, located just a leisurely stroll away. Next, head to Rocca Paolina, a photogenic historical landmark, also available for your discovery today.
At the end of the day, you will drive to Rome, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.
As you explore more of Rome, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.
Begin your culinary exploration in Rome by securing a reservation at La Pergola. This renowned restaurant holds 3 Michelin star and offers an exceptional menu of mediterranean and contemporary cuisine. For another dining delight, visit Il Pagliaccio, celebrated for its delectable creative and innovative menu. This acclaimed 2-star Michelin-recipient consistently leaves guests satisfied, making it a must-visit during your holiday. Looking for a different experience? Discover Enoteca La Torre, a top local spot known for its tantalizing mediterranean and creative menu. With a 2-star Michelin recognition, it guarantees an exceptional dining adventure.
After savoring a delicious meal, step into the vibrant nightlife at La Botticella Of Poggi Giovanni, where the evening is just getting started. In the same way, Almalu Trastevere offers a unique charm perfect for experiencing the local bar scene in Rome. Bar Viminale Di Pepi Maurilio is another top-recommended bar that is sure to get you into the mood for some dancing and celebrating.
As the sun sets on another day of adventure, rest up and recharge for the next leg of your road trip in Italy.
Day 3
- Rome
- More
Drive 8 km, 1 hour 2 min
- Trevi Fountain
- Pantheon
- Piazza Navona
- Campo de' Fiori
- Castel Sant'Angelo
- More
Day 3 of your road trip across Italy promises a magnificent time exploring Rome. You have 3 nights left in Rome. Take the opportunity to experience more of the best attractions and activities in the city.
Set out on a day brimming with family-friendly attractions, romantic experiences, and breathtaking views. Start at the globally renowned Trevi Fountain, an enchanting monument in Rome. Next, go to Pantheon.
After visiting Trevi Fountain and Pantheon, have a stroll along Rome's streets and take in the local charm. Continue your sightseeing by heading to Piazza Navona. This masterful public square offers a unique experience. Campo De' Fiori is another noteworthy attraction worthwhile a visit. End your self-guided sightseeing tour on top with a visit to Castel Sant'angelo, one of the most visually striking places to visit in Rome.
Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.
As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Rome. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.
Make sure to reserve a table at RomAntica, an iconic dining spot in Rome. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Coso Ristorante, a popular restaurant in Rome. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of DEROMA - Farine Romane, a hidden gem nestled in Rome. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.
Continue your evening by exploring the vibrant nightlife scene at Sant' Eustachio Caffè, a prime destination for a thrilling night out. Also, don’t forget to check out Yellowsquare Rome, a bar that offers unique local touches. Likewise, Caffè Portofino provides an excellent alternative for a fun evening.
Take some time to reflect on your day and savor another beautiful night in Italy.
Day 4
- Rome
- More
Drive 8 km, 1 hour 14 min
- largo di Torre Argentina
- Altare della Patria
- Roman Forum
- Colosseum
- Basilica di Santa Maria Maggiore
- More
Day 4 offers a multitude of experiences. You will stay in Rome for 2 nights more, offering you enough time to explore at a relaxed pace.
Rome is brimming with adventures. Today’s wonderful stops include an archeological site, a monument, and a church. Begin your sightseeing adventure at the interesting Largo Di Torre Argentina and allow yourself time to explore. Just a short distance away you'll find your next stop, Altare Della Patria, a picture-perfect monument that draws visitors from far and near.
Continue your journey to Roman Forum, one of the city’s most iconic spots that you shouldn’t miss. Another great site to visit is the globally renowned Colosseum. When you're finished at the archeological site, Basilica Di Santa Maria Maggiore awaits your visit. This church is a culturally significant highlight on today's itinerary.
Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.
After a day of adventure, treat yourself to an exquisite dinner at one of Rome's best restaurants.
Treat yourself to a delicious dinner at Hotel de Russie, an excellent option for tonight's dining. Looking for something different? La Taverna Italiana offers a tantalizing alternative with its diverse menu. And don’t miss The Parrot Bar. With its reputation for pleasing customers, it’s a fantastic choice for tonight in Rome.
If you’re not ready to end the night just yet, The Apartment Bar Roma offers a perfect venue to relax and savor a drink. Similarly, Hotel Hassler Roma is well-suited for those looking to unwind in a social setting.
Savor another day of unforgettable experiences in Italy!
Day 5
- Rome
- More
Drive 11 km, 1 hour 4 min
- Spanish Steps
- Piazza di Spagna
- piazza del Popolo
- Villa Borghese
- Circus Maximus
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On day 5 of your road trip, you will have an entire day to explore Rome. You’ll stay in Rome for 1 night and discover all the best things to see and do in the area.
Whether you prefer a leisurely exploration or a more fast-paced adventure, this itinerary in Rome allows for both. Start by heading to Spanish Steps. This famous public square provides an insightful glimpse into the city's identity. Next, discover Piazza Di Spagna, a romantic public square, promising a delightful encounter.
Continue your sightseeing with a visit to Piazza Del Popolo, an astonishing public square. When you’re done, don’t forget to make a stop at the extraordinary Villa Borghese. Round off your day at Circus Maximus, another gem in Rome with historic features to discover.
Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.
As you explore more of Rome, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.
Enjoy a lovely meal at Sofitel Roma Villa Borghese, a top-rated place to have dinner tonight. Alternatively, if your taste buds call for something different, Centro is another top choice with a popular menu. You could also check for a table at Ristorante Tema. As an establishment that gains consistently high praises from customers, it’s an ideal choice in Rome tonight.
Get a good night's sleep and look forward to another great day on the road in Italy!
Day 6
- Rome
- Siena
- More
Drive 244 km, 3 hours 28 min
- St Peter's Basilica
- Sistine Chapel
- Saint Peter's Square
- Vatican Museums
- More
Embark on another extraordinary experience on day 6 of your road trip in Italy. Today, you will make 1 stop and experience some of the highlights of Vatican City. At the end of the day, you will enjoy the comforts of a top-rated hotel in Siena, which will be your home away from home for 2 nights.
Begin your sightseeing with St. Peter's Basilica. This globally renowned major basilica is one of the top attractions in the city. Proceed to Sistine Chapel, another must-visit attraction.
As you wander through the inviting streets of Rome, soak in the lively ambiance and take the opportunity to snap some photos. Next, head to Saint Peter's Square. This notable square is a traveler-favorite. Not far away, you’ll find Vatican Museums, another key site on your sightseeing itinerary.
After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Siena. Siena offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.
As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Siena. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.
Treat yourself to a delicious dinner at Enoteca I Terzi, an excellent option for tonight's dining. Looking for something different? Ristorante Tar-Tufo offers a tantalizing alternative with its diverse menu. And don’t miss Antica Trattoria Papei. With its reputation for pleasing customers, it’s a fantastic choice for tonight in Siena.
Cap off your culinary experience with a visit to some of the most celebrated bars in the area. For instance, Meet Life Cafè stands out as an excellent choice for a post-dinner cocktail. Alternatively, Maudit Pub offers an ideal atmosphere to enjoy the pleasures of the night. Bar Impero Siena is also a great option that provides a perfect setting for a relaxing evening.
Take some time to reflect on your day and savor another beautiful night in Italy.
Day 7
- Siena
- More
Drive 2 km, 41 min
- Porta Romana
- Pubblico Palace
- piazza del Campo
- Tower of Mangia
- Siena Cathedral
- More
Day 7 of your road trip will take you to the best attractions Siena has to offer. Cherish the 1 night you have left in Siena by discovering the best things there are to see and do in the city.
Get ready to discover some of the most iconic wonders in Siena, including a monument, a palace, a public square, a church and much more! Start your day at Porta Romana. This standout monument is an up-and-coming place to see in Siena. Then, wander over to Pubblico Palace. If picture-perfect sites excite you, this palace will be right up your alley. Nearby, you’ll also find Piazza Del Campo. This romantic public square is a favorite among visitors.
Siena offers plenty to explore, ensuring every moment of your visit is filled with excitement and discovery. If you're up for more, Tower Of Mangia is an up-and-coming spot in the city that will captivate you with its unique charm. When you’re done at the monument, don’t forget to check out the enchanting Siena Cathedral. Take a moment to appreciate the fascinating details of this popular church.
Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.
As dinnertime approaches, it's time to head out for a bite to eat in Siena. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.
Enjoy a delicious meal at Osteria Quattro Venti, a top-rated dining destination in Siena. If you're in the mood to try something new, consider Fischi per Fiaschi, another top spot with a mouthwatering menu. You might also want to secure a reservation at Osteria da Divo. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Siena this evening.
Extend your evening after a delightful meal by visiting Charlie Mixology Bar Di Aldinucci Riccardo, which offers the perfect atmosphere for a night out. Moreover, Bar Pinacoteca is another popular option for a drink or two. Likewise, San Paolo Pub also provides a great ambiance for reminiscing about the day and raising a toast to your vacation.
Head back to your accommodation in Siena and get some rest in preparation for another magical day of your road trip in Italy!
Day 8
- Siena
- Arezzo
- More
Drive 74 km, 1 hour 45 min
- Palazzo Salimbeni
- Santuario di Santa Caterina
- Basilica of San Domenico
- Fortezza Medicea
- Porta Camollia, Siena
- More
On day 8 of your road trip in Italy, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Siena. In the evening, you’ll end up in Arezzo, where you will stay for 2 nights.
Today’s itinerary in Siena covers several incredible sights, including a palace, a church, and a monument. Start your adventure at Palazzo Salimbeni. This increasingly popular palace is a place that is appreciated by travelers and locals alike. Next, immerse yourself in the photogenic wonders of Santuario Di Santa Caterina, a must-see church in the city.
Consider stopping for a small bite to eat or a drink at a local eatery to keep your energy going. When you’re ready, continue your discovery with a visit to Basilica Of San Domenico. This worthwhile church offers an enriching experience. For a change of pace, head to Fortezza Medicea (siena), where you can take in historic features. Conclude your self-guided sightseeing tour with a visit to Porta Camollia, Siena. These sights offer a fulfilling end to a perfect day.
When you’re done exploring for the day, you’ll drive to your hotel in Arezzo. Check in and spend some time relaxing before you head out to tour the city.
After a day of adventure, treat yourself to an exquisite dinner at one of Arezzo's best restaurants.
Prepare for an extraordinary culinary adventure in Arezzo by booking a table at Octavin, a 1-star Michelin restaurant that boasts an exceptional creative menu. If you're eager to try something different, consider La Clandestina, another top spot with a tantalizing menu.
To truly maximize your evening out, consider visiting Liquid Bar after dinner. This bar is known for offering some of the best drinks and vibes in the city.
Head back to your accommodation in Arezzo and get some rest in preparation for another magical day of your road trip in Italy!
Day 9
- Arezzo
- More
Drive 2 km, 40 min
- Roman Amphitheatre of Arezzo
- San Francesco, Arezzo
- piazza Grande
- The Medici Fortress Park
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Day 9 of your road trip across Italy promises a magnificent time exploring Arezzo. You have 1 night left in Arezzo. Take the opportunity to experience more of the best attractions and activities in the city.
Get ready for an exciting day in Arezzo. Today’s sightseeing agenda includes an archeological site, a church, a public square, a park and much more! Begin your adventure at Roman Amphitheatre Of Arezzo. This is an intriguing archeological site you should not miss. Another must-see is San Francesco, Arezzo, an intriguing church in Arezzo.
When you’re ready for the next sight, head to Piazza Grande. From there, take a leisurely stroll to The Medici Fortress Park, another of the city’s beloved attractions.
Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.
After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Arezzo. Enjoy a satisfying meal that will recharge you for tonight's adventures.
Enjoy a delicious meal at La Nuova Tagliatella, a highly-rated dining destination in Arezzo. If you're eager to try something different, consider i 3 bicchieri, another top spot with a tantalizing menu. You might also want to secure a reservation at Il Cantuccio. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Arezzo this evening.
As the sun sets on another day of adventure, rest up and recharge for the next leg of your road trip in Italy.
Day 10
- Arezzo
- Perugia
- More
Drive 98 km, 1 hour 39 min
- Casa Vasari
- San Domenico
- Arezzo Cathedral
- More
On day 10 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 1 destination, Arezzo. When you’re not sightseeing, take time to relax at your selected hotel in Perugia, where you’ll be staying for 1 night.
Get ready for a day filled with fun adventures, picturesque spots, and history-rich sites in the charming city of Arezzo. Your adventure starts at Casa Vasari, an up-and-coming local hot spot. Another notable attraction to explore is San Domenico. This worthwhile church is known for its historic appeal.
After soaking in the highlights of these sights, take some time to wander Arezzo's streets and immerse yourself in the local atmosphere. When you're ready to continue your sightseeing adventure, head to Arezzo Cathedral. This grand church offers a fascinating experience that many visitors find memorable.
At the end of the day, you will drive to Perugia, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.
After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Perugia. Enjoy a satisfying meal that will recharge you for tonight's adventures.
Don’t miss out on dining at La Taverna, a top-rated dining destination in Perugia. If you're in the mood to try something new, consider Ristorante del Sole, another top spot with a mouthwatering menu. You might also want to secure a reservation at Al Mangiar Bene. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Perugia this evening.
Extend your evening after a delightful meal by visiting Caffè Fortebraccio, which offers the perfect atmosphere for a night out. Moreover, Caffe Del Banco is another popular option for a drink or two. Likewise, Dempsey's Perugia also provides a great ambiance for reminiscing about the day and raising a toast to your vacation.
Relax and reminisce about your day in Italy and look forward to more memorable moments to come!
Day 11
- Perugia - Departure day
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- Etruscan Arch
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Day 11 of your road trip in Italy is your departure day. This is your chance to catch a last glimpse of Perugia before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.
If you're up for some more sightseeing, begin at Etruscan Arch. This curiosity-inducing historical landmark is a popular place to see in the city.
On your last day in Italy, take time to indulge in shopping at Perugia’s popular marketplace. Look for keepsakes or souvenirs to remind you of your trip.
Before you conclude your road trip in Italy, drop by another restaurant for a last chance at a memorable dining experience in Perugia.
Savor the flavors at Perugia Plaza Hotel, a top pick for dinner tonight. Alternatively, Elfo Pub Perugia beckons with its unique menu offerings.
You’ll then say farewell to Perugia. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Italy!
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