11-Day Italy Self-Drive Road Trip With Itinerary from Pescara traveling west to Rome, Florence, Siena, and Perugia
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Description
Escape the ordinary with this exciting 11-day road trip through Italy. Explore the diverse landscapes, lively cities, and beyond. Pack your bags, hit the road, and prepare for an unforgettable journey!
This perfectly planned road trip itinerary in Italy takes you through some of the best places to see in the country. You will spend 2 nights in Pescara, 2 nights in Rome, 2 nights in Florence, 2 nights in Siena, and 2 nights in Perugia. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!
With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Italy. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have got you covered.
Upon arriving in Pescara, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Italy on your own terms.
An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Italy. Trevi Fountain and Colosseum are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Pantheon, learn more about the unique Piazza Navona, and immerse yourself in the vibrant atmosphere of St. Peter's Basilica.
As you hit the open road and drive through Pescara, Rome, Florence, Pisa, Lucca, Siena, Santa Maria degli Angeli, Perugia, Fano Adriano, and Pietracamela, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Italy. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Italy.
Throughout your road trip in Italy, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Italy.
This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodation, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.
The best services in Italy fill up quickly, so book your spot early. Select a date and start planning your road trip in Italy today!
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Day 1
- Pescara - Arrival day
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- Locomotiva FS 740351
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Your road trip adventure in Italy begins as soon as you reach Pescara and pick up your car. You’ll stay in Pescara for 1 night and explore the best things to see and do, sample the local cuisine, and choose from a curated selection of the best hotels and places to stay in the city.
Pescara is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Locomotiva Fs 740.351, or just taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.
Make your way to your chosen hotel. Check-in typically starts between 2 and 4 PM in Pescara. Make yourself at home and enjoy some downtime before heading out again.
As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Pescara, it's often a good idea to reserve a table in advance.
Have a fantastic dining experience at Taverna 58, a highly recommended choice for tonight's dinner. If you're looking to mix things up, Ristorante Carlo Ferraioli offers an enticing alternative with its varied menu. Additionally, Sesamo Nero is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Pescara.
Unwind after your meal by stepping into Posa Caffè Pescara. This venue is celebrated for its extensive drink selections and cozy vibes. Alternatively, Bar Mixer offers a dynamic and energetic atmosphere for a glass or two. Don’t overlook Temple Bar Irish Pub, another top-rated bar in the area.
Raise a toast to the start of your 11-day road trip in Italy!
Day 2
- Pescara
- Rome
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Drive 213 km, 3 hours 15 min
- Colosseum
- Roman Forum
- Altare della Patria
- Pantheon
- Piazza Navona
- More
On day 2 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 1 destination, Rome. When you’re not sightseeing, take time to relax at your selected hotel in Rome, where you’ll be staying for 2 nights.
Today’s route brings fun adventures, breathtaking views, and picturesque spots. The first attraction of today is Colosseum. This world-famous archeological site is a breathtaking place to see in Pescara. Continue your discovery at Roman Forum, a picture-perfect archeological site with stories to tell.
As you stroll around Pescara, take in the distinct atmosphere and learn what makes this city so unique. Maximize your sightseeing with a visit to Altare Della Patria. This popular monument offers a picture-perfect encounter with Pescara. Next, make your way to Pantheon to add another highlight to your day. After that, visit Piazza Navona, a globally renowned public square that’s sure to impress. Whether you decide to get entrance tickets for all attractions or you prefer admiring from a distance, amazing experiences await on this day in Pescara.
After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Rome. Rome offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.
As you explore more of Rome, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.
Make sure to reserve a table at La Bottega Roma, an iconic dining spot in Rome. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Pasta In Corso, a popular restaurant in Rome. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Trattoria Vecchia Roma, a hidden gem nestled in Rome. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.
After savoring a delicious meal, step into the vibrant nightlife at La Botticella Of Poggi Giovanni, where the evening is just getting started. In the same way, Almalu Trastevere offers a unique charm perfect for experiencing the local bar scene in Rome. Bar Viminale Di Pepi Maurilio is another top-recommended bar that is sure to get you into the mood for some dancing and celebrating.
Take some time to reflect on your day and savor another beautiful night in Italy.
Day 3
- Rome
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Drive 9 km, 57 min
- St Peter's Basilica
- piazza del Popolo
- Piazza di Spagna
- Trevi Fountain
- Trastevere
- Via del Corso
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Wake up to day 3 of your extraordinary road trip in Italy. With 1 night left in Rome, we encourage you to seize the day and discover the unexplored beauty of the city’s surroundings!
One of the most iconic places you can visit today in Vatican City is Trastevere. Allow yourself some time to explore this neighborhood and discover its unique quirks. You'll also find many of the best sightseeing spots nearby. You can also explore Via del Corso, a street that offers a glimpse into local life and culture.
Whether you prefer a leisurely exploration or a more fast-paced adventure, this itinerary in Rome allows for both. Start by heading to St. Peter's Basilica. This wondrous major basilica provides an insightful glimpse into the city's identity. Next, discover Piazza Del Popolo, a visually striking public square, promising a delightful encounter.
Continue your sightseeing with a visit to Piazza Di Spagna, a timeless public square. When you’re done, don’t forget to make a stop at the world-famous Trevi Fountain.
When you’re done exploring for the day, you’ll return to Rome and your accommodation.
After a day of adventure, treat yourself to an exquisite dinner at one of Rome's best restaurants.
Treat yourself to a delightful dinner at RomAntica, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Coso Ristorante? It's another excellent option with a diverse menu. Consider reserving a table at DEROMA - Farine Romane as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Rome.
Extend your evening after a delightful meal by visiting Sant' Eustachio Caffè, which offers the perfect atmosphere for a night out. Moreover, Yellowsquare Rome is another popular option for a drink or two. Likewise, Caffè Portofino also provides a great ambiance for reminiscing about the day and raising a toast to your vacation.
As the sun sets on another day of adventure, rest up and recharge for the next leg of your road trip in Italy.
Day 4
- Rome
- Florence
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Drive 282 km, 3 hours 36 min
- The Boboli Gardens
- Ponte Vecchio
- Uffizi Gallery
- Loggia dei Lanzi
- piazza della Signoria
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Embark on another extraordinary experience on day 4 of your road trip in Italy. Today, you will make 1 stop and experience some of the highlights of Florence. At the end of the day, you will enjoy the comforts of a top-rated hotel in Florence, which will be your home away from home for 2 nights.
Today's adventure in Rome promises more breathtaking discoveries and enriching experiences! Begin at The Boboli Gardens. This noteworthy botanical garden is a highlight of any visit in the city. Then, enjoy Ponte Vecchio, another romantic attraction that never fails to captivate visitors. Next, head over to Uffizi Gallery, one of the city’s most spectacular attractions, known for its standout features.
If you’re looking for more, spend time soaking in the atmosphere of Loggia Dei Lanzi. This enchanting public square is frequented by locals and tourists alike. To complete your memorable day, make sure to visit Piazza Della Signoria, an astonishing public square, and take a stroll around the area.
When you’re done exploring for the day, you’ll drive to your hotel in Florence. Check in and spend some time relaxing before you head out to tour the city.
After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Florence. Enjoy a satisfying meal that will recharge you for tonight's adventures.
Enjoy a lovely dining experience at Ristorante Oliviero 1962, a popular restaurant in Florence. This acclaimed establishment has earned the admiration of countless food lovers in the city. Alternatively, experience a taste of Florence at Di Poneta Novoli, another great place to eat. With a menu designed to impress, it promises a journey of flavors that will leave you captivated. A third option to check out is the top-rated Caffe San Firenze. It’s yet another ideal choice to enhance your time in Florence tonight.
Continue your evening by exploring the vibrant nightlife scene at Manifattura, a prime destination for a thrilling night out. Also, don’t forget to check out Se·sto On Arno Rooftop Bar, a bar that offers unique local touches. Likewise, Il Vinile provides an excellent alternative for a fun evening.
Relax and recharge in preparation for another adventurous day in Italy!
Day 5
- Florence
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Drive 6 km, 1 hour 32 min
- piazzale Michelangelo
- Basilica of Santa Croce in Florence
- Cathedral of Santa Maria del Fiore
- Central Market
- Galleria dell'Accademia
- David
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Day 5 of your road trip across Italy promises a magnificent time exploring Florence. You have 1 night left in Florence. Take the opportunity to experience more of the best attractions and activities in the city.
Get ready for a day filled with family-friendly attractions, romantic experiences, and breathtaking views in the charming city of Florence. Your adventure starts at Piazzale Michelangelo, an impressive local hot spot. Another notable attraction to explore is Basilica Of Santa Croce In Florence. This well-known church is known for its respected appeal.
After soaking in the highlights of these sights, take some time to wander Florence's streets and immerse yourself in the local atmosphere. When you're ready to continue your sightseeing adventure, head to Cathedral Of Santa Maria Del Fiore. This grand church offers a fascinating experience that many visitors find memorable. Central Market is also worth visiting, along with Galleria Dell'accademia. These standout landmarks offer unique experiences that add to the day’s enjoyment. End your day at David. This notable statue provides a fitting finale to your sightseeing.
Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.
As you explore more of Florence, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.
Have a fantastic dining experience at Ditta Artigianale, a highly recommended choice for tonight's dinner. If you're looking to mix things up, Trattoria Da Burde offers an enticing alternative with its varied menu. Additionally, Casa Toscana is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Florence.
Continue your evening by exploring the vibrant nightlife scene at Bar 50 Rosso, a prime destination for a thrilling night out. Also, don’t forget to check out Bitter Bar, a bar that offers unique local touches. Likewise, Archea Brewery provides an excellent alternative for a fun evening.
Get a good night's sleep and look forward to another great day on the road in Italy!
Day 6
- Florence
- Siena
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Drive 245 km, 3 hours 33 min
- Pisa Cathedral
- Piazza del Duomo, Pisa
- Leaning Tower of Pisa
- Walls of Lucca
- Porta San Pietro
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Dive into day 6 of your remarkable road trip in Italy. Today you will explore Pisa and Lucca, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Siena. You’ll stay here for 2 nights.
Brace yourself for today’s incredible lineup of attractions in Florence, featuring family-friendly attractions, scenic views, and photo-friendly spots. Start at Pisa Cathedral, an underrated church in the city. Then, head to Piazza Del Duomo, Pisa and soak in the ambiance of this culturally significant public square.
There are many interesting places to see in Florence, and when you are ready for more, go to Leaning Tower Of Pisa. This is one of the city’s most wondrous culturally significant spots of interest. After exploring the monument, visit the worthwhile Mura Di Lucca. Not far away, you'll also find Porta San Pietro. This monument is an awe-inspiring highlight in Florence.
At the end of the day, you will drive to Siena, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.
As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Siena. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.
Treat yourself to a wonderful meal at Enoteca I Terzi, a top-rated dining spot in Siena. If you're in the mood for something new, try Ristorante Tar-Tufo, another premier location with a delectable menu. You might also want to book a table at Antica Trattoria Papei. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Siena.
After enjoying a fulfilling meal, continue your evening at Meet Life Cafè, ideal for those looking to unwind with a drink in a comfortable setting. Alternatively, Maudit Pub offers a welcoming atmosphere for easing into the nightlife. Similarly, Bar Impero Siena provides an excellent environment for a relaxed and enjoyable evening.
As the sun sets on another day of adventure, rest up and recharge for the next leg of your road trip in Italy.
Day 7
- Siena
- More
Drive 3 km, 59 min
- Porta Camollia, Siena
- Fortezza Medicea
- Fontebranda
- Battistero di San Giovanni Battista
- Siena Cathedral
- piazza del Campo
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Day 7 offers a multitude of experiences. You will stay in Siena for 1 night more, offering you enough time to explore at a relaxed pace.
Today’s agenda in Siena includes a monument, a historical landmark, a church, a public square and much more! Porta Camollia, Siena is must-visit monument and a great starting point for the day. Next, continue your journey to Fortezza Medicea (siena), a locally appreciated monument, located just a leisurely stroll away. Next, head to Fontebranda, a respected historical landmark, also available for your discovery today.
Each stop on today’s itinerary promises to leave you with lasting memories and a deeper appreciation for Siena. When you're ready, let your sightseeing route take you to the intriguing Battistero Di San Giovanni Battista. If you’re looking for more, Siena Cathedral is also a notable attraction that is worthwhile a visit. Lastly, don’t miss Piazza Del Campo, a place of visually striking interest in the city.
Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.
Indulge in a memorable dining experience at one of Siena's most popular restaurants, and connect with friendly locals for an authentic adventure.
Enjoy a lovely meal at Osteria Quattro Venti, a top-rated place to have dinner tonight. Alternatively, if your taste buds call for something different, Fischi per Fiaschi is another top choice with a popular menu. You could also check for a table at Osteria da Divo. As an establishment that gains consistently high praises from customers, it’s an ideal choice in Siena tonight.
Following your dinner, dive into the local bar culture at Charlie Mixology Bar Di Aldinucci Riccardo. Enjoy this evening's relaxed ambiance with delightful drinks. Alternatively, go to Bar Pinacoteca, the perfect place for those looking to experience the best of the nightlife. Similarly, San Paolo Pub provides excellent drinks and a great atmosphere, ensuring a memorable night out.
Take some time to reflect on your day and savor another beautiful night in Italy.
Day 8
- Siena
- Perugia
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Drive 158 km, 2 hours 50 min
- Basilica of San Francesco d'Assisi
- Piazza del Comune
- Mount Subasio
- San Damiano
- More
Experience an unparalleled adventure on day 8 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 1 vibrant destinations - Santa Maria degli Angeli. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Perugia. You will spend 2 nights here for some well-deserved relaxation.
Discover a day packed with fun adventures, breathtaking views, and photo-friendly spots in Siena. Begin your sightseeing with Basilica Of San Francesco D'assisi. This locally renowned church is one of the top attractions in the town. Proceed to Piazza Del Comune, another must-visit attraction.
As you wander through the inviting streets of Siena, soak in the lively ambiance and take the opportunity to snap some photos. Next, head to Mount Subasio. This beloved mountain range is a traveler-favorite. Not far away, you’ll find San Damiano, another key site on your sightseeing itinerary.
After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Perugia. Perugia offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.
After a day of adventure, treat yourself to an exquisite dinner at one of Perugia's best restaurants.
Don’t miss out on dining at Ristorante Settimo Sigillo, a top-rated dining destination in Perugia. If you're in the mood to try something new, consider Caffè Baglioni, another top spot with a mouthwatering menu. You might also want to secure a reservation at Bar Pellas. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Perugia this evening.
Round off your dining experience by visiting Tommi Bar, a prime location for a drink. Alternatively, explore the distinctive characteristics of Valentina, a bar catering to every mood and preference. Caffe Dal Perugino likewise offers a unique atmosphere, perfect for a memorable night out.
Raise your glass and celebrate another amazing day of your road trip in Italy!
Day 9
- Perugia
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Drive 4 km, 1 hour 2 min
- Chiesa di San Michele Arcangelo
- Acquedotto medievale di Perugia
- Perugia Sotterranea Accesso
- Piazza IV Novembre
- Rocca Paolina
- National Archaeological Museum of Umbria
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On day 9 of your road trip, you will have an entire day to explore Perugia. You’ll stay in Perugia for 1 night and discover all the best things to see and do in the area.
Today's adventure in Perugia promises more breathtaking discoveries and enriching experiences! Begin at Chiesa Di San Michele Arcangelo. This culturally significant church is a highlight of any visit in the city. Then, enjoy Acquedotto Medievale Di Perugia, another picture-perfect attraction that never fails to captivate visitors. Next, head over to Perugia Sotterranea Accesso, one of the city’s most up-and-coming attractions, known for its visually striking features.
If you’re looking for more, spend time soaking in the atmosphere of Piazza Iv Novembre. This enchanting public square is frequented by locals and tourists alike. To complete your memorable day, make sure to visit Rocca Paolina, a worthwhile historical landmark, and take a stroll around the area. If you want to extend your self-guided sightseeing tour, go check out National Archaeological Museum Of Umbria before you head back to your hotel.
Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.
As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Perugia. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.
Enjoy a lovely dining experience at La Taverna, a popular restaurant in Perugia. This acclaimed establishment has earned the admiration of countless food lovers in the city. Alternatively, experience a taste of Perugia at Ristorante del Sole, another great place to eat. With a menu designed to impress, it promises a journey of flavors that will leave you captivated. A third option to check out is the top-rated Al Mangiar Bene. It’s yet another ideal choice to enhance your time in Perugia tonight.
Continue the enjoyment post-dinner at Caffè Fortebraccio, a cherished local gathering spot renowned for its welcoming atmosphere. Similarly, Caffe Del Banco offers a vibrant space for indulging in well-crafted drinks and engaging conversation. You may also want to check out Dempsey's Perugia. This bar is a favorite among both locals and visitors looking for a delightful evening out filled with laughter and fun.
As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in in Italy.
Day 10
- Perugia
- Pescara
- More
Drive 333 km, 6 hours 1 min
- Gran Sasso e Monti della Laga National Park
- Cascata del Rio Arno
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On day 10 of your road trip in Italy, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Fano Adriano and Pietracamela. In the evening, you’ll end up in Pescara, where you will stay for 1 night.
Get ready for an exciting day in Perugia. Today’s sightseeing agenda includes a national park and a waterfall. Begin your adventure at Gran Sasso E Monti Della Laga National Park. This is a well-known national park you should not miss. Another must-see is Cascata Del Rio Arno, a beloved waterfall in Perugia.
When you’re done exploring for the day, you’ll drive to your hotel in Pescara. Check in and spend some time relaxing before you head out to tour the city.
As dinnertime approaches, it's time to head out for a bite to eat in Pescara. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.
Have a fantastic dining experience at Ciacco, a highly recommended choice for tonight's dinner. If you're looking to mix things up, Bar Sara offers an enticing alternative with its varied menu. Additionally, Ristorante Franco is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Pescara.
Continue your lively evening at Bar Napoli, a perfect place for winding down or revving up the night, depending on which mood you’re in. Bar Supermarket is another excellent bar that offers a great selection of drinks to suit any mood. If you prefer to go somewhere else, Post Bar ensures a night out tailored to your taste.
Head back to your accommodation in Pescara and get some rest in preparation for another magical day of your road trip in Italy!
Day 11
- Pescara - Departure day
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- Parrocchia Spirito Santo
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Day 11 of your road trip in Italy is your departure day. This is your chance to catch a last glimpse of Pescara before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.
If you're up for some more sightseeing, begin at Parrocchia Spirito Santo. This intriguing church is a popular place to see in the city.
Make the most of your final day in Italy by visiting Pescara’s iconic markets and shopping establishments in the buzzing Centro Commerciale Pescara Porta Nuova. Secure the perfect souvenirs for your family and friends back home or buy yourself a remembrance of your amazing experience in Italy.
Before you conclude your road trip in Italy, drop by another restaurant for a last chance at a memorable dining experience in Pescara.
You’ll then say farewell to Pescara. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Italy!
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