6-Day Italy Self-Drive Road Trip With Itinerary from Pisa to Florence, Siena, and Lucca and surrounding area

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Experience the freedom of the open road in Italy as you embark on an unforgettable 6-day road trip! This experience caters to every traveler, featuring destinations like Pisa, Florence, Siena, San Gimignano, Lucca, Corniglia, Vernazza, and Manarola.

This perfectly planned road trip itinerary in Italy takes you through some of the best places to see in the country. You will spend 2 nights in Pisa, 1 night in Florence, 1 night in Siena, and 1 night in Lucca. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Italy. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have got you covered.

Upon arriving in Pisa, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Italy on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Italy. Ponte Vecchio and Leaning Tower Of Pisa are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Piazza Del Duomo, Pisa, learn more about the unique Piazzale Michelangelo, and immerse yourself in the vibrant atmosphere of Cathedral Of Santa Maria Del Fiore.

As you hit the open road and drive through Pisa, Florence, Siena, San Gimignano, Lucca, Corniglia, Vernazza, and Manarola, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Italy. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Italy.

Throughout your road trip in Italy, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Italy.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodation, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Italy fill up quickly, so book your spot early. Select a date and start planning your road trip in Italy today!

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Driver’s age is 30 - 65
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Itinerary summary

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Days
Destination
Attractions
Overnight
Day
City & Overnight
Attractions
Knights' Square
Leaning Tower of PisaPiazza del Duomo, PisaPisa Cathedralpiazzale MichelangeloGalleria dell'AccademiaCathedral of Santa Maria del Fiore
piazza della SignoriaPonte VecchioUffizi GalleryBasilica of Santa Croce in FlorenceSiena Cathedralpiazza del Campo
Piazza del Duomo, San GimignanoPiazza dell'AnfiteatroGuinigi TowerSt Martin CathedralPorta San PietroWalls of Lucca
Scalinata LardarinaChiesa Di San PietroRuins of Doria TowerChurch of St. Margaret of AntiochCinque Terre National ParkManarola Overlook Viewpoint
Palazzo Blu

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Day 1

Day 1

  • Pisa - Arrival day
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  • Knights' Square
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Welcome to Pisa, the perfect starting point for your road trip in Italy! Pick up your rental car and let the adventure begin. You will spend 1 night immersing yourself in Pisa's charm before embarking on the next leg of your journey.

Pisa is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Knights' Square, or just taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

Make your way to your chosen hotel. Check-in typically starts between 2 and 4 PM in Pisa. Make yourself at home and enjoy some downtime before heading out again.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Pisa, it's often a good idea to reserve a table in advance.

Don’t miss out on dining at Anima di Grano Pizzeria Napoletana Pisa Italy, a top-rated dining destination in Pisa. If you're in the mood to try something new, consider il Mercante, another top spot with a mouthwatering menu. You might also want to secure a reservation at La Ghiotteria. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Pisa this evening.

Keep the evening going at Jeffer Cocktails & Friends, a great choice for enjoying the after-dinner hours with a drink. You could also go to Le Parisien Wine Bar, which offers a similarly pleasant setting and great drinks. Another option is Las Volta Cocktailbar, which provides an inviting environment for unwinding after a busy day out.

Raise a toast to the start of your 6-day road trip in Italy!

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Day 2

Day 2

  • Pisa
  • Florence
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Drive 96 km, 2 hours 2 min

  • Leaning Tower of Pisa
  • Piazza del Duomo, Pisa
  • Pisa Cathedral
  • piazzale Michelangelo
  • Galleria dell'Accademia
  • Cathedral of Santa Maria del Fiore
  • More

Embark on another extraordinary experience on day 2 of your road trip in Italy. Today, you will make 2 stops and experience some of the highlights of Pisa and Florence. At the end of the day, you will enjoy the comforts of a top-rated hotel in Florence, which will be your home away from home for 1 night.

Get ready for a day filled with family-friendly attractions, breathtaking views, and picturesque spots in the charming city of Pisa. Your adventure starts at Leaning Tower Of Pisa, an iconic local hot spot. Another notable attraction to explore is Piazza Del Duomo, Pisa. This iconic public square is known for its remarkable appeal.

After soaking in the highlights of these sights, take some time to wander Pisa's streets and immerse yourself in the local atmosphere. When you're ready to continue your sightseeing adventure, head to Pisa Cathedral. This breathtaking church offers a fascinating experience that many visitors find memorable. Piazzale Michelangelo is also worth visiting, along with Galleria Dell'accademia. These standout landmarks offer unique experiences that add to the day’s enjoyment. End your day at Cathedral Of Santa Maria Del Fiore. This astonishing church provides a fitting finale to your sightseeing.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Florence. Florence offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

Indulge in a memorable dining experience at one of Florence's most popular restaurants, and connect with friendly locals for an authentic adventure.

Savor the flavors at Ristorante Oliviero 1962, a top pick for dinner tonight. Alternatively, Di Poneta Novoli beckons with its unique menu offerings. Also, consider Caffe San Firenze. With its consistent customer satisfaction, it’s an excellent option for dining in Florence tonight.

After your delicious meal, get a taste of the vibrant nightlife with a visit to Manifattura, known for its inviting atmosphere. Se·sto On Arno Rooftop Bar is another great option if you’re looking for a place to get the night started. Similarly, Il Vinile provides a great setting to enjoy the night away.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in in Italy.

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Day 3

Day 3

  • Florence
  • Siena
  • More

Drive 80 km, 1 hour 34 min

  • piazza della Signoria
  • Ponte Vecchio
  • Uffizi Gallery
  • Basilica of Santa Croce in Florence
  • Siena Cathedral
  • piazza del Campo
  • More

On day 3 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 2 destinations, Florence and Siena. When you’re not sightseeing, take time to relax at your selected hotel in Siena, where you’ll be staying for 1 night.

Enjoy the perfect balance of relaxation and exploration in Florence today. One of the most top-rated attractions included on the itinerary is Piazza Della Signoria. This visually striking public square will help you start your sightseeing on top. Then, take a leisurely stroll to Ponte Vecchio and learn what makes this culturally significant historical landmark unique.

Throughout the day, make sure to take breaks to appreciate the surroundings. Next up, visit the impressive Uffizi Gallery. After exploring the art gallery, head to Basilica Of Santa Croce In Florence. This locally renowned church is a highlight in Florence. As your day continues, stop by Siena Cathedral, known for its inviting features. Lastly, don’t forget to check out the extraordinary Piazza Del Campo. Enjoy exploring this incredible public square at your own pace.

When you’re done exploring for the day, you’ll drive to your hotel in Siena. Check in and spend some time relaxing before you head out to tour the city.

After a day of adventure, treat yourself to an exquisite dinner at one of Siena's best restaurants.

Treat yourself to a delicious dinner at Enoteca I Terzi, an excellent option for tonight's dining. Looking for something different? Ristorante Tar-Tufo offers a tantalizing alternative with its diverse menu. And don’t miss Antica Trattoria Papei. With its reputation for pleasing customers, it’s a fantastic choice for tonight in Siena.

Explore the vibrant nightlife at Meet Life Cafè after your meal, a hub for lively evenings and memorable moments. Or, head to Maudit Pub for a great selection of flavorful drinks and a charming setting. Furthermore, Bar Impero Siena is perfect for those looking to extend their night with a touch of local flavor.

Get a good night's sleep and look forward to another great day on the road in Italy!

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Day 4

Day 4

  • Siena
  • Lucca
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Drive 126 km, 2 hours 52 min

  • Piazza del Duomo, San Gimignano
  • Piazza dell'Anfiteatro
  • Guinigi Tower
  • St Martin Cathedral
  • Porta San Pietro
  • Walls of Lucca
  • More

On day 4 of your road trip in Italy, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in San Gimignano and Lucca. In the evening, you’ll end up in Lucca, where you will stay for 1 night.

Today’s itinerary in Siena covers several incredible sights, including a public square, a monument, a church, a historical landmark and much more! Start your adventure at Piazza Del Duomo. This often recommended public square is a place that is appreciated by travelers and locals alike. Next, immerse yourself in the enchanting wonders of Piazza Dell'anfiteatro, a must-see public square in the village.

Consider stopping for a small bite to eat or a drink at a local eatery to keep your energy going. When you’re ready, continue your discovery with a visit to Guinigi Tower. This underrated monument offers an enriching experience. For a change of pace, head to St Martin Cathedral, where you can take in stunning features. Conclude your self-guided sightseeing tour with a visit to Porta San Pietro and Mura Di Lucca. These sights offer a fulfilling end to a perfect day.

At the end of the day, you will drive to Lucca, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As you explore more of Lucca, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Treat yourself to a delightful dinner at Gli Orti di Via Elisa, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Bar Caffè Ristretto? It's another excellent option with a diverse menu. Consider reserving a table at Ristorante Schiaffino as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Lucca.

Keep the excitement of the evening going by visiting a bar or two. Lebowski - Cocktail Bar is an excellent place to start. You could also check out Blend, offering a different kind of charm. A last recommendation for the day is Franklin'33. This bar promises an enjoyable experience with tasty drinks and a vibrant setting.

Raise your glass to another unforgettable day in Italy!

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Day 5

Day 5

  • Lucca
  • Pisa
  • More

Drive 226 km, 4 hours 9 min

  • Scalinata Lardarina
  • Chiesa Di San Pietro
  • Ruins of Doria Tower
  • Church of St. Margaret of Antioch
  • Cinque Terre National Park
  • Manarola Overlook Viewpoint
  • More

Experience an unparalleled adventure on day 5 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 3 vibrant destinations - Corniglia, Vernazza, and Manarola. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Pisa. You will spend 1 night here for some well-deserved relaxation.

Get ready to discover some of the most iconic wonders in Lucca, including a hiking area, a church, a monument, a national park, an observation deck and much more! Start your day at Scalinata Lardarina. This romantic hiking area is a worthwhile place to see in Lucca. Then, wander over to Chiesa Di San Pietro. If inviting sites excite you, this church will be right up your alley. Nearby, you’ll also find Ruins Of Doria Tower. This romantic monument is a favorite among visitors.

Lucca offers plenty to explore, ensuring every moment of your visit is filled with excitement and discovery. If you're up for more, Church Of St. Margaret Of Antioch is an up-and-coming spot in the village that will captivate you with its unique charm. When you’re done at the church, don’t forget to check out the UNESCO world heritage-listed Cinque Terre National Park. Take a moment to appreciate the fascinating details of this captivating national park. Wrap up your self-guided tour of Lucca's top attractions with a visit to Manarola Overlook Viewpoint.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Pisa. Pisa offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Pisa. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Make sure to reserve a table at Ristorante Capodimonte Pisa, an iconic dining spot in Pisa. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of La Locanda Dei Pisani Doc Pisa, a popular restaurant in Pisa. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Baribaldi Pisa, a hidden gem nestled in Pisa. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Round off your dining experience by visiting Bar Mocambo, a prime location for a drink. Alternatively, explore the distinctive characteristics of Tree, a bar catering to every mood and preference. Chupiteria likewise offers a unique atmosphere, perfect for a memorable night out.

Raise your glass and celebrate another amazing day of your road trip in Italy!

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Day 6

Day 6

  • Pisa - Departure day
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  • Palazzo Blu
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Day 6 of your road trip in Italy is your departure day. This is your chance to catch a last glimpse of Pisa before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, we recommend visiting Palazzo Blu, a history-steeped art gallery before you head out.

Maximize your last day in Italy and go on a shopping spree in Pisa’s shopping center. Browse for souvenirs to remind you of your wonderful journey in Italy.

Before you conclude your road trip in Italy, drop by another restaurant for a last chance at a memorable dining experience in Pisa.

Dine in style at Restaurant -Pizzeria Il Mio Capriccio, a top recommendation for dinner tonight. Or, for a change of pace, Ristorante alle Bandierine boasts a menu that's sure to impress.

You’ll then say farewell to Pisa. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Italy!

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