10-Day Italy Self-Drive Road Trip With Itinerary from Venice traveling west to Verona, Florence, Siena, and Rome
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Explore the best of Italy on a 10-day road trip! Uncover hidden gems and experience the rich culture firsthand as you journey through Venice, Murano, Burano, Verona, Sirmione, Desenzano Del Garda, Gardone Riviera, Florence, Pisa, Siena, and Rome. This road trip itinerary in Italy seamlessly combines exploration with relaxation.
This perfectly planned road trip itinerary in Italy takes you through some of the best places to see in the country. You will spend 3 nights in Venice, 2 nights in Verona, 2 nights in Florence, 1 night in Siena, and 1 night in Rome. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!
With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Italy. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have got you covered.
Upon arriving in Venice, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Italy on your own terms.
An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Italy. Trevi Fountain and Colosseum are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Pantheon, learn more about the unique Piazza Navona, and immerse yourself in the vibrant atmosphere of Rialto Bridge.
As you hit the open road and drive through Venice, Murano, Burano, Verona, Sirmione, Desenzano Del Garda, Gardone Riviera, Florence, Pisa, Siena, and Rome, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Italy. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Italy.
Throughout your road trip in Italy, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Italy.
This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodation, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.
The best services in Italy fill up quickly, so book your spot early. Select a date and start planning your road trip in Italy today!
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Day 1
- Venice - Arrival day
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- Rialto Bridge
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Welcome to Venice, the perfect starting point for your road trip in Italy! Pick up your rental car and let the adventure begin. You will spend 2 nights immersing yourself in Venice's charm before embarking on the next leg of your journey.
Venice is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Rialto Bridge, or just taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.
As afternoon approaches, head to your chosen hotel in Venice. Check-in typically starts around 2 to 4 PM at hotels in Italy. We recommend staying at a hotel in a central location for easy access to the best attractions, restaurants, and bars in the city.
As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Venice, it's often a good idea to reserve a table in advance.
Treat yourself to a delicious dinner at Bauer Hotel, an excellent option for tonight's dining. Looking for something different? L'Osteria Le Guglie offers a tantalizing alternative with its diverse menu. And don’t miss Corner Pub. With its reputation for pleasing customers, it’s a fantastic choice for tonight in Venice.
To truly maximize your evening out, consider visiting Al Parlamento after dinner. This bar is known for offering some of the best drinks and vibes in the city. Alternatively, head to The Caffe Rosso, another bar with an inviting ambiance. Similarly, Adagio also offers a great atmosphere, ensuring a night filled with enjoyment and relaxation.
Raise a toast to the start of your 10-day road trip in Italy!
Day 2
- Venice
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Drive 128 km, 2 hours 50 min
- campo San Maurizio
- St Mark's Basilica
- Doge's Palace
- Murano
- Burano
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On day 2 of your road trip in Italy, you’ll start and end your day in Venice, but spend the day exploring what’s beyond the city. Since you will return to Venice for 1 night more, there’s no need to rush. Experience Venice, Murano, and Burano to the fullest today with this curated day itinerary!
Prepare for a day full of family-friendly attractions, romantic experiences, and breathtaking views. When you’re ready, kick off your sightseeing adventure at Campo San Maurizio. This worthwhile public square is a must-visit for anyone seeking a unique vacation experience. Another sight you shouldn’t miss is St Mark's Basilica, one of the city’s best highlights.
Next, check out Doge's Palace, one of the most popular places to see in Venice. This palace is a favorite among locals and travelers alike. Enjoy some downtime and refreshments before continuing to your next stop, Murano. Wander around and soak in the instagrammable atmosphere this handicraft store offers. Then, head to Burano, a top-rated street that adds another dimension to your day.
When you’re done exploring for the day, you’ll return to Venice and your accommodation.
As you explore more of Venice, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.
Savor the flavors at Generator Venice, a top pick for dinner tonight. Alternatively, Nevodi beckons with its unique menu offerings. Also, consider Ristorante La Piazza. With its consistent customer satisfaction, it’s an excellent option for dining in Venice tonight.
Round off your dining experience by visiting Il Mercante, a prime location for a drink. Alternatively, explore the distinctive characteristics of The Irish Pub Venezia, a bar catering to every mood and preference. Ai Stagneri likewise offers a unique atmosphere, perfect for a memorable night out.
Relax and reminisce about your day in Italy and look forward to more memorable moments to come!
Day 3
- Venice
- Verona
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Drive 119 km, 2 hours 4 min
- Giusti Garden
- piazza delle Erbe
- Porta Borsari
- Castelvecchio Museum
- Castelvecchio Bridge
- Verona Arena
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Embark on another extraordinary experience on day 3 of your road trip in Italy. Today, you will make 1 stop and experience some of the highlights of Verona. At the end of the day, you will enjoy the comforts of a top-rated hotel in Verona, which will be your home away from home for 2 nights.
Savor the day by visiting some of the best places to see in Venice, including a botanical garden, a public square, a historical landmark, a museum, a monument, a stadium and much more! Start your adventure at Giusti Garden. This locally appreciated botanical garden is a must-visit for travelers looking for a unique holiday experience. Make your way to Piazza Delle Erbe located in Venice for another exciting encounter.
Next, immerse yourself in the setting of Porta Borsari. Its symbolic features will captivate you. After the historical landmark, continue your tour of the city with a visit to Castelvecchio Museum. Visitors usually appreciate the breathtaking features of this museum. Next up is Castelvecchio Bridge, a highly recommended monument. For a change of pace, head to Verona Arena. As one of the most timeless attractions in Venice, this stadium is the perfect place to end your self-guided sightseeing tour.
At the end of the day, you will drive to Verona, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.
After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Verona. Enjoy a satisfying meal that will recharge you for tonight's adventures.
Make sure to reserve a table at La Griglia, an iconic dining spot in Verona. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Vecio Macello, a popular restaurant in Verona. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Via Fama Cafè | Verona, a hidden gem nestled in Verona. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.
Unwind after your meal by stepping into Archivio. This venue is celebrated for its extensive drink selections and cozy vibes. Alternatively, La Segreteria Café offers a dynamic and energetic atmosphere for a glass or two. Don’t overlook Grande Giove Cocktail Bar, another top-rated bar in the area.
Take some time to reflect on your day and savor another beautiful night in Italy.
Day 4
- Verona
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Drive 149 km, 3 hours 32 min
- Archaeological site of Grotte di Catullo
- Castello di Sirmione
- Castello di Desenzano del Garda
- Duomo di Santa Maria Maddalena
- Villa Romana di Desenzano del Garda
- Vittoriale degli italiani
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Greet day 4 of your road trip in Italy with a smile and start your day with a hearty breakfast. You will return to Verona for your remaining 1 night in the city later today, but first, it’s time for some exploring! On the agenda for this day, you’ll find only the best things to see and do in Sirmione, Desenzano Del Garda, and Gardone Riviera.
Discover a day packed with family-friendly attractions, romantic experiences, and scenic views in Verona. Begin your sightseeing with Archaeological Site Of Grotte Di Catullo. This captivating archeological site is one of the top attractions in the town. Proceed to Scaliger Castle, another must-visit attraction.
As you wander through the inviting streets of Verona, soak in the lively ambiance and take the opportunity to snap some photos. Next, head to Castello Di Desenzano Del Garda. This increasingly popular castle is a traveler-favorite. Not far away, you’ll find Duomo Di Santa Maria Maddalena, another key site on your sightseeing itinerary. Villa Romana Di Desenzano Del Garda is yet another highly recommended place to visit nearby, offering plenty to discover for curious travelers. Conclude your day at Vittoriale Degli Italiani and uncover why it's recognized as one of the town's most captivating attractions.
When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Verona.
As dinnertime approaches, it's time to head out for a bite to eat in Verona. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.
Treat yourself to a delicious dinner at Trattoria I Masenini, an excellent option for tonight's dining. Looking for something different? Osteria da Ugo offers a tantalizing alternative with its diverse menu. And don’t miss Locanda 4 Cuochi. With its reputation for pleasing customers, it’s a fantastic choice for tonight in Verona.
After savoring a delicious meal, step into the vibrant nightlife at Duchi Café, where the evening is just getting started. In the same way, Cambridge Bar offers a unique charm perfect for experiencing the local bar scene in Verona. Rubicone Caffe is another top-recommended bar that is sure to get you into the mood for some dancing and celebrating.
Celebrate another amazing day of your road trip adventure in Italy!
Day 5
- Verona
- Florence
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Drive 237 km, 3 hours 4 min
- Piazza della Repubblica
- Ponte Vecchio
- Uffizi Gallery
- Basilica of Santa Croce in Florence
- Palazzo Vecchio
- piazza della Signoria
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On day 5 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 1 destination, Florence. When you’re not sightseeing, take time to relax at your selected hotel in Florence, where you’ll be staying for 2 nights.
Get ready to discover some of the most iconic wonders in Verona, including a public square, a historical landmark, an art gallery, a church, a palace and much more! Start your day at Piazza Della Repubblica. This enchanting public square is a popular place to see in Verona. Then, wander over to Ponte Vecchio. If history-steeped sites excite you, this historical landmark will be right up your alley. Nearby, you’ll also find Uffizi Gallery. This romantic art gallery is a favorite among visitors.
Verona offers plenty to explore, ensuring every moment of your visit is filled with excitement and discovery. If you're up for more, Basilica Of Santa Croce In Florence is a well-known spot in the city that will captivate you with its unique charm. When you’re done at the church, don’t forget to check out the visually striking Palazzo Vecchio. Take a moment to appreciate the fascinating details of this locally renowned palace. Wrap up your self-guided tour of Verona's top attractions with a visit to Piazza Della Signoria.
When you’re done exploring for the day, you’ll drive to your hotel in Florence. Check in and spend some time relaxing before you head out to tour the city.
As you explore more of Florence, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.
Savor the flavors at Ristorante Oliviero 1962, a top pick for dinner tonight. Alternatively, Di Poneta Novoli beckons with its unique menu offerings. Also, consider Caffe San Firenze. With its consistent customer satisfaction, it’s an excellent option for dining in Florence tonight.
After your meal, keep the night alive at a bar like Manifattura, known for its lively atmosphere. Se·sto On Arno Rooftop Bar is another top recommendation that provides the perfect setting with well-crafted drinks and a welcoming ambiance. Similarly, Il Vinile offers an excellent atmosphere for those looking to amp up the evening.
Relax and reminisce about your day in Italy and look forward to more memorable moments to come!
Day 6
- Florence
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Drive 176 km, 3 hours 2 min
- Santa Maria della Spina
- Putti fountain
- Leaning Tower of Pisa
- Pisa Cathedral
- Piazza del Duomo, Pisa
- Campo santo
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On day 6 of your road trip, you’ll start and end your day in Florence, but spend part of the day exploring places of interest outside the immediate city. On today's itinerary, you'll find attractions in Pisa. You still have 1 night left in Florence.
Continue your journey to Leaning Tower Of Pisa, one of the city’s most iconic spots that you shouldn’t miss. Another great site to visit is the underrated Pisa Cathedral. When you're finished at the church, Piazza Del Duomo, Pisa awaits your visit. This public square is a majestic highlight on today's itinerary. Last up is a cemetery - the underrated Campo Santo.
When you’re done exploring for the day, you’ll return to Florence and your accommodation.
After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Florence. Enjoy a satisfying meal that will recharge you for tonight's adventures.
Treat yourself to a wonderful meal at Ditta Artigianale, a top-rated dining spot in Florence. If you're in the mood for something new, try Trattoria Da Burde, another premier location with a delectable menu. You might also want to book a table at Casa Toscana. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Florence.
After your meal, keep the night alive at a bar like Bar 50 Rosso, known for its lively atmosphere. Bitter Bar is another top recommendation that provides the perfect setting with well-crafted drinks and a welcoming ambiance. Similarly, Archea Brewery offers an excellent atmosphere for those looking to amp up the evening.
Raise your glass and celebrate another amazing day of your road trip in Italy!
Day 7
- Florence
- Siena
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Drive 79 km, 1 hour 31 min
- Basilica of San Domenico
- Siena Cathedral
- Pubblico Palace
- piazza del Campo
- Tower of Mangia
- Loggia del Papa, Siena
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Dive into day 7 of your remarkable road trip in Italy. Today you will explore Siena, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Siena. You’ll stay here for 1 night.
Florence is brimming with adventures. Today’s wonderful stops include a church, a palace, a public square, a monument and much more! Begin your sightseeing adventure at the beloved Basilica Of San Domenico and allow yourself time to explore. Just a short distance away you'll find your next stop, Siena Cathedral, a history-steeped church that draws visitors from far and near.
Continue your journey to Pubblico Palace, one of the city’s most up-and-coming spots that you shouldn’t miss. Another great site to visit is the famous Piazza Del Campo. When you're finished at the public square, Tower Of Mangia awaits your visit. This monument is a culturally significant highlight on today's itinerary. Last up is a monument - the up-and-coming Loggia Del Papa, Siena.
After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Siena. Siena offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.
After a day of adventure, treat yourself to an exquisite dinner at one of Siena's best restaurants.
Enjoy a delicious meal at Enoteca I Terzi, a highly-rated dining destination in Siena. If you're eager to try something different, consider Ristorante Tar-Tufo, another top spot with a tantalizing menu. You might also want to secure a reservation at Antica Trattoria Papei. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Siena this evening.
After your delicious meal, get a taste of the vibrant nightlife with a visit to Meet Life Cafè, known for its inviting atmosphere. Maudit Pub is another great option if you’re looking for a place to get the night started. Similarly, Bar Impero Siena provides a great setting to enjoy the night away.
As the sun sets on another day of adventure, rest up and recharge for the next leg of your road trip in Italy.
Day 8
- Siena
- Rome
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Drive 247 km, 3 hours 32 min
- Colosseum
- Roman Forum
- St Peter's Basilica
- Piazza Navona
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Experience an unparalleled adventure on day 8 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 2 vibrant destinations - Rome and Vatican City. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Rome. You will spend 1 night here for some well-deserved relaxation.
Whether you prefer a leisurely exploration or a more fast-paced adventure, this itinerary in Siena allows for both. Start by heading to Colosseum. This wondrous archeological site provides an insightful glimpse into the city's identity. Next, discover Roman Forum, a historic archeological site, promising a delightful encounter.
Continue your sightseeing with a visit to St. Peter's Basilica, an iconic major basilica. When you’re done, don’t forget to make a stop at the wondrous Piazza Navona.
At the end of the day, you will drive to Rome, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.
As dinnertime approaches, it's time to head out for a bite to eat in Rome. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.
Enjoy a delicious meal at La Bottega Roma, a top-rated dining destination in Rome. If you're in the mood to try something new, consider Pasta In Corso, another top spot with a mouthwatering menu. You might also want to secure a reservation at Trattoria Vecchia Roma. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Rome this evening.
To truly maximize your evening out, consider visiting La Botticella Of Poggi Giovanni after dinner. This bar is known for offering some of the best drinks and vibes in the city. Alternatively, head to Almalu Trastevere, another bar with an inviting ambiance. Similarly, Bar Viminale Di Pepi Maurilio also offers a great atmosphere, ensuring a night filled with enjoyment and relaxation.
Relax and recharge in preparation for another adventurous day in Italy!
Day 9
- Rome
- Venice
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Drive 530 km, 6 hours 2 min
- Pantheon
- Trevi Fountain
- Piazza di Spagna
- Spanish Steps
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On day 9 of your road trip in Italy, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Rome. In the evening, you’ll end up in Venice, where you will stay for 1 night.
A blend of family-friendly attractions, photo-friendly spots, and historic treasures await you in Rome on today’s itinerary. First up is the iconic monument, Pantheon. Afterward, continue to Trevi Fountain, a monument every traveler should visit.
As you explore Rome’s charming streets, take in the lively atmosphere and get to know the character of the city. Next, make your way to Piazza Di Spagna. This iconic public square is an essential stop. Following that, head to Spanish Steps, another must-visit site that will enhance your experience.
When you’re done exploring for the day, you’ll drive to your hotel in Venice. Check in and spend some time relaxing before you head out to tour the city.
As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Venice. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.
Dine in style at Osteria Alla Staffa, a top recommendation for dinner tonight. Or, for a change of pace, Bistrot de Venise boasts a menu that's sure to impress. Also, be sure to check out Corte Sconta. Known as a local hotspot, it’s a great choice for tonight in Venice.
Extend your evening after a delightful meal by visiting Dolce Vita Venezia, which offers the perfect atmosphere for a night out. Moreover, Tarnowska's American Bar is another popular option for a drink or two. Likewise, Bar All'angolo also provides a great ambiance for reminiscing about the day and raising a toast to your vacation.
Get a good night's sleep and look forward to another great day on the road in Italy!
Day 10
- Venice - Departure day
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- Grand Canal
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Day 10 of your road trip in Italy is your departure day. This is your chance to catch a last glimpse of Venice before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.
If you're up for some more sightseeing, begin at Grand Canal. This intriguing street is a popular place to see in the city.
As your final day in Italy unfolds, enjoy a last-minute shopping spree in Venice's best shopping area, Calle Larga XXII Marzo. Enjoy finding the perfect gift or keepsake to remind you of your wonderful trip to Italy. Explore high-end stores offering an exquisite selection of luxury items.
Before you conclude your road trip in Italy, drop by another restaurant for a last chance at a memorable dining experience in Venice.
Savor the flavors at Cantina Do Spade, a top pick for dinner tonight. Alternatively, Trattoria Al Gazzettino beckons with its unique menu offerings.
You’ll then say farewell to Venice. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Italy!
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