10-Day Italy Self-Drive Road Trip With Itinerary from Rome to Florence and Venice

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Explore the best of Italy on a 10-day road trip! Uncover hidden gems and experience the rich culture firsthand as you journey through Rome, Florence, Pisa, Riomaggiore, Manarola, Corniglia, Vernazza, Venice, Bologna, and Orvieto. This road trip itinerary in Italy seamlessly combines exploration with relaxation.

This perfectly planned road trip itinerary in Italy takes you through some of the best places to see in the country. You will spend 3 nights in Rome, 2 nights in Florence, 2 nights in San Bernardino, and 2 nights in Venice. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Italy. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have got you covered.

Upon arriving in Rome, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Italy on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Italy. Trevi Fountain and Colosseum are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Pantheon, learn more about the unique Piazza Navona, and immerse yourself in the vibrant atmosphere of Piazza San Marco.

As you hit the open road and drive through Rome, Florence, Pisa, Riomaggiore, Manarola, Corniglia, Vernazza, Venice, Bologna, and Orvieto, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Italy. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Italy.

Throughout your road trip in Italy, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Italy.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodation, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Italy fill up quickly, so book your spot early. Select a date and start planning your road trip in Italy today!

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Driver’s age is 30 - 65
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Itinerary summary

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Days
Destination
Attractions
Overnight
Day
City & Overnight
Attractions
Palatine Hill
ColosseumRoman ForumTrevi FountainSpanish StepsPiazza NavonaTrastevere
piazzale MichelangeloBasilica of Santa Croce in FlorenceUffizi GalleryPonte Vecchiopiazza della Signoria
Palazzo PittiCathedral of Santa Maria del FioreGalleria dell'AccademiaCentral MarketBasilica of Santa Maria NovellaOltrarno
Pisa CathedralPiazza del Duomo, PisaLeaning Tower of PisaKnights' SquareLungarni di PisaSantuario di Nostra Signora di Montenero
RiomaggioreCastle of RiomaggioreManarola Overlook ViewpointCinque Terre National ParkSentiero Monterosso - Vernazza

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Day 1

Day 1

  • Rome - Arrival day
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  • Palatine Hill
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Your road trip adventure in Italy begins as soon as you reach Rome and pick up your car. You’ll stay in Rome for 2 nights and explore the best things to see and do, sample the local cuisine, and choose from a curated selection of the best hotels and places to stay in the city.

Rome is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Palatine Hill, or just taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

Make your way to your chosen hotel. Check-in typically starts between 2 and 4 PM in Rome. Make yourself at home and enjoy some downtime before heading out again.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Rome, it's often a good idea to reserve a table in advance.

Treat yourself to a delightful dinner at La Bottega Roma, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Pasta In Corso? It's another excellent option with a diverse menu. Consider reserving a table at Trattoria Vecchia Roma as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Rome.

Continue the enjoyment post-dinner at La Botticella Of Poggi Giovanni, a cherished local gathering spot renowned for its welcoming atmosphere. Similarly, Almalu Trastevere offers a vibrant space for indulging in well-crafted drinks and engaging conversation. You may also want to check out Bar Viminale Di Pepi Maurilio. This bar is a favorite among both locals and visitors looking for a delightful evening out filled with laughter and fun.

Raise a toast to the start of your 10-day road trip in Italy!

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Day 2

Day 2

  • Rome
  • More

Drive 6 km, 1 hour 24 min

  • Colosseum
  • Roman Forum
  • Trevi Fountain
  • Spanish Steps
  • Piazza Navona
  • Trastevere
  • More

Day 2 of your road trip will take you to the best attractions Rome has to offer. Cherish the 1 night you have left in Rome by discovering the best things there are to see and do in the city.

Trastevere is one of the highlights of today. Take your time exploring this iconic neighborhood in Rome, which offers a perfect blend of history and culture. Plus, it's close to many must-see landmarks in the city.

Enjoy the perfect balance of relaxation and exploration in Rome today. One of the most iconic attractions included on the itinerary is Colosseum. This UNESCO world heritage-listed archeological site will help you start your sightseeing on top. Then, take a leisurely stroll to Roman Forum and learn what makes this culturally significant archeological site unique.

Throughout the day, make sure to take breaks to appreciate the surroundings. Next up, visit the timeless Trevi Fountain. After exploring the monument, head to Spanish Steps. This impressive public square is a highlight in Rome. As your day continues, stop by Piazza Navona, known for its remarkable features.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

Elevate your experience in Rome with a visit to the city's premier shopping location, Trastevere. Explore unique boutique shops and uncover hidden gems along the way. For a cultural touch, look for artisan crafts that perfectly capture the charm of Italy. After shopping, enjoy nearby attractions or simply people-watch and capture memorable photos.

Indulge in a memorable dining experience at one of Rome's most popular restaurants, and connect with friendly locals for an authentic adventure.

Treat yourself to a wonderful meal at RomAntica, a top-rated dining spot in Rome. If you're in the mood for something new, try Coso Ristorante, another premier location with a delectable menu. You might also want to book a table at DEROMA - Farine Romane. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Rome.

After enjoying a fulfilling meal, continue your evening at Sant' Eustachio Caffè, ideal for those looking to unwind with a drink in a comfortable setting. Alternatively, Yellowsquare Rome offers a welcoming atmosphere for easing into the nightlife. Similarly, Caffè Portofino provides an excellent environment for a relaxed and enjoyable evening.

Get a good night's sleep and look forward to another great day on the road in Italy!

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Day 3

Day 3

  • Rome
  • Florence
  • More

Drive 281 km, 3 hours 45 min

  • piazzale Michelangelo
  • Basilica of Santa Croce in Florence
  • Uffizi Gallery
  • Ponte Vecchio
  • piazza della Signoria
  • More

Dive into day 3 of your remarkable road trip in Italy. Today you will explore Florence, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Florence. You’ll stay here for 2 nights.

Get ready to discover some of the most iconic wonders in Rome, including an observation deck, a church, an art gallery, a historical landmark, a public square and much more! Start your day at Piazzale Michelangelo. This awe-inspiring observation deck is an impressive place to see in Rome. Then, wander over to Basilica Of Santa Croce In Florence. If monumental sites excite you, this church will be right up your alley. Nearby, you’ll also find Uffizi Gallery. This picture-perfect art gallery is a favorite among visitors.

Rome offers plenty to explore, ensuring every moment of your visit is filled with excitement and discovery. If you're up for more, Ponte Vecchio is a wondrous spot in the city that will captivate you with its unique charm. When you’re done at the historical landmark, don’t forget to check out the visually striking Piazza Della Signoria. Take a moment to appreciate the fascinating details of this extraordinary public square.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Florence. Florence offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

Indulge in a memorable dining experience at one of Florence's most popular restaurants, and connect with friendly locals for an authentic adventure.

Treat yourself to a wonderful meal at Ristorante Oliviero 1962, a top-rated dining spot in Florence. If you're in the mood for something new, try Di Poneta Novoli, another premier location with a delectable menu. You might also want to book a table at Caffe San Firenze. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Florence.

Continue your lively evening at Manifattura, a perfect place for winding down or revving up the night, depending on which mood you’re in. Se·sto On Arno Rooftop Bar is another excellent bar that offers a great selection of drinks to suit any mood. If you prefer to go somewhere else, Il Vinile ensures a night out tailored to your taste.

Head back to your accommodation in Florence and get some rest in preparation for another magical day of your road trip in Italy!

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Day 4

Day 4

  • Florence
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Drive 4 km, 1 hour 3 min

  • Palazzo Pitti
  • Cathedral of Santa Maria del Fiore
  • Galleria dell'Accademia
  • Central Market
  • Basilica of Santa Maria Novella
  • Oltrarno
  • More

Day 4 of your road trip across Italy promises a magnificent time exploring Florence. You have 1 night left in Florence. Take the opportunity to experience more of the best attractions and activities in the city.

A visit to Oltrarno in Florence is a must on the agenda today. This neighborhood is full of hidden gems and character, perfect for a leisurely stroll. Plus, you’ll be close to some of the city’s most famous sights.

Today’s itinerary in Florence covers several incredible sights, including a palace, a church, an art gallery, a food market and much more! Start your adventure at Pitti Palace. This popular palace is a place that is appreciated by travelers and locals alike. Next, immerse yourself in the visually striking wonders of Cathedral Of Santa Maria Del Fiore, a must-see church in the city.

Consider stopping for a small bite to eat or a drink at a local eatery to keep your energy going. When you’re ready, continue your discovery with a visit to Galleria Dell'accademia. This notable art gallery offers an enriching experience. For a change of pace, head to Central Market, where you can take in picture-perfect features. Conclude your self-guided sightseeing tour with a visit to Basilica Di Santa Maria Novella, Firenze (fi). These sights offer a fulfilling end to a perfect day.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

As dinnertime approaches, it's time to head out for a bite to eat in Florence. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Savor the flavors at Ditta Artigianale, a top pick for dinner tonight. Alternatively, Trattoria Da Burde beckons with its unique menu offerings. Also, consider Casa Toscana. With its consistent customer satisfaction, it’s an excellent option for dining in Florence tonight.

If you’re not ready to end the night just yet, Bar 50 Rosso offers a perfect venue to relax and savor a drink. Similarly, Bitter Bar is well-suited for those looking to unwind in a social setting. Archea Brewery is another excellent spot to enjoy a nightcap after a delightful meal.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in in Italy.

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Day 5

Day 5

  • Florence
  • More

Drive 195 km, 3 hours 15 min

  • Pisa Cathedral
  • Piazza del Duomo, Pisa
  • Leaning Tower of Pisa
  • Knights' Square
  • Lungarni di Pisa
  • Santuario di Nostra Signora di Montenero
  • More

On day 5 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 2 destinations, Pisa and Riomaggiore. When you’re not sightseeing, take time to relax at your selected hotel in San Bernardino, where you’ll be staying for 2 nights.

Today, you'll explore some of the most beautiful places in Florence, including a church, a public square, a monument, a street and much more! Start your day with a visit to Pisa Cathedral. This increasingly popular church is a must-visit in the city. When you’re ready for your next discovery, continue to Piazza Del Duomo, Pisa, which may be one of the most historic places you will experience today.

One of the best things about exploring Florence on a self-guided tour is that you set the pace. There’s plenty of time for detours and discovering hidden gems. When you’re ready for your next stop, make your way to Leaning Tower Of Pisa, a globally renowned monument in the city. If you’re up for more discoveries, don’t forget to reserve some time for Knights' Square and Lungarni Di Pisa. End your day with a visit to Nostra Signora Di Montenero, a locally appreciated church that’s sure to leave a lasting impression.

At the end of the day, you will drive to San Bernardino, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in San Bernardino. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Get a good night's sleep and look forward to another great day on the road in Italy!

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Day 6

Day 6

San Bernardino, Riomaggiore, Manarola, Corniglia, and Vernazza

Drive 32 km, 1 hour 50 min

  • Riomaggiore
  • Castle of Riomaggiore
  • Manarola Overlook Viewpoint
  • Cinque Terre National Park
  • Sentiero Monterosso - Vernazza
  • More

Greet day 6 of your road trip in Italy with a smile and start your day with a hearty breakfast. You will return to San Bernardino for your remaining 1 night in the hamlet later today, but first, it’s time for some exploring! On the agenda for this day, you’ll find only the best things to see and do in Riomaggiore, Manarola, Corniglia, and Vernazza.

Set out on a day brimming with fun adventures, romantic experiences, and scenic views. Next, go to Castle Of Riomaggiore.

After visiting Riomaggiore and Castle Of Riomaggiore, have a stroll along San Bernardino's streets and take in the local charm. Continue your sightseeing by heading to Manarola Overlook Viewpoint. This eye-catching observation deck offers a unique experience. Cinque Terre National Park is another noteworthy attraction worthwhile a visit. End your self-guided sightseeing tour on top with a visit to Sentiero Monterosso - Vernazza, one of the most stunning places to visit in San Bernardino.

When you’re done exploring for the day, you’ll return to San Bernardino and your accommodation.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in San Bernardino. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Take some time to reflect on your day and savor another beautiful night in Italy.

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Day 7

Day 7

  • Venice
  • More

Drive 390 km, 5 hours 9 min

  • Bridge of Sighs
  • Doge's Palace
  • St Mark's Basilica
  • St Mark's Campanile
  • Piazza San Marco
  • More

Experience an unparalleled adventure on day 7 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 1 vibrant destinations - Venice. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Venice. You will spend 2 nights here for some well-deserved relaxation.

Discover a day packed with fun adventures, romantic experiences, and breathtaking views in San Bernardino. Begin your sightseeing with Bridge Of Sighs. This interesting monument is one of the top attractions in the city. Proceed to Doge's Palace, another must-visit attraction.

As you wander through the inviting streets of San Bernardino, soak in the lively ambiance and take the opportunity to snap some photos. Next, head to St Mark's Basilica. This popular church is a traveler-favorite. Not far away, you’ll find St Mark's Campanile, another key site on your sightseeing itinerary. Piazza San Marco is yet another highly recommended place to visit nearby, offering plenty to discover for curious travelers.

When you’re done exploring for the day, you’ll drive to your hotel in Venice. Check in and spend some time relaxing before you head out to tour the city.

As dinnertime approaches, it's time to head out for a bite to eat in Venice. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Enjoy a lovely meal at Bauer Hotel, a top-rated place to have dinner tonight. Alternatively, if your taste buds call for something different, L'Osteria Le Guglie is another top choice with a popular menu. You could also check for a table at Corner Pub. As an establishment that gains consistently high praises from customers, it’s an ideal choice in Venice tonight.

After savoring a delicious meal, step into the vibrant nightlife at Al Parlamento, where the evening is just getting started. In the same way, The Caffe Rosso offers a unique charm perfect for experiencing the local bar scene in Venice. Adagio is another top-recommended bar that is sure to get you into the mood for some dancing and celebrating.

Savor another day of unforgettable experiences in Italy!

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Day 8

Day 8

  • Venice
  • More

Drive 4 km, 56 min

  • Santa Maria della Salute
  • Peggy Guggenheim Collection
  • Gallerie dell'Accademia
  • Palazzo Contarini del Bovolo
  • Rialto Bridge
  • Grand Canal
  • More

Day 8 offers a multitude of experiences. You will stay in Venice for 1 night more, offering you enough time to explore at a relaxed pace.

Bring your curiosity for today’s adventure around Venice. Some of the city’s most loved attractions await! Santa Maria Della Salute is the perfect place to start. This church is one of the most up-and-coming places to visit in Venice. Next, head to Peggy Guggenheim Collection, an interesting art gallery, known for its remarkable features.

In between the sights, don’t hesitate to take small detours to explore local stores and eateries. When you’re ready to continue your adventure, head to Gallerie Dell'accademia. This visually striking art gallery is a highly recommended experience. Nearby, you'll also find Palazzo Contarini Del Bovolo and Rialto Bridge. Visit these for an interesting touch to your journey. Finish the day with a visit to Grand Canal, an UNESCO world heritage-designated street in Venice.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

After a day of adventure, treat yourself to an exquisite dinner at one of Venice's best restaurants.

Dine in style at Generator Venice, a top recommendation for dinner tonight. Or, for a change of pace, Nevodi boasts a menu that's sure to impress. Also, be sure to check out Ristorante La Piazza. Known as a local hotspot, it’s a great choice for tonight in Venice.

Keep the excitement of the evening going by visiting a bar or two. Il Mercante is an excellent place to start. You could also check out The Irish Pub Venezia, offering a different kind of charm. A last recommendation for the day is Ai Stagneri. This bar promises an enjoyable experience with tasty drinks and a vibrant setting.

Relax and recharge in preparation for another adventurous day in Italy!

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Day 9

Day 9

  • Venice
  • Rome
  • More

Drive 555 km, 6 hours 36 min

  • Two Towers
  • Palazzo del Podestà, Bologna
  • Piazza Maggiore
  • Torre dell'Orologio
  • Orvieto Cathedral
  • More

On day 9 of your road trip in Italy, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Bologna and Orvieto. In the evening, you’ll end up in Rome, where you will stay for 1 night.

Get ready for a day filled with fun adventures, breathtaking views, and photo-friendly spots in the charming city of Venice. Your adventure starts at Two Towers, a popular local hot spot. Another notable attraction to explore is Palazzo Del Podestà, Bologna. This frequently visited palace is known for its picture-perfect appeal.

After soaking in the highlights of these sights, take some time to wander Venice's streets and immerse yourself in the local atmosphere. When you're ready to continue your sightseeing adventure, head to Piazza Maggiore. This visually striking public square offers a fascinating experience that many visitors find memorable. Torre Dell'orologio is also worth visiting, along with Orvieto Cathedral. These standout landmarks offer unique experiences that add to the day’s enjoyment.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Rome. Rome offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

As you explore more of Rome, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Enjoy a delicious meal at Hotel de Russie, a highly-rated dining destination in Rome. If you're eager to try something different, consider La Taverna Italiana, another top spot with a tantalizing menu. You might also want to secure a reservation at The Parrot Bar. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Rome this evening.

To truly maximize your evening out, consider visiting The Apartment Bar Roma after dinner. This bar is known for offering some of the best drinks and vibes in the city. Alternatively, head to Hotel Hassler Roma, another bar with an inviting ambiance.

Raise your glass to another unforgettable day in Italy!

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Day 10

Day 10

  • Rome - Departure day
  • More
  • Pantheon
  • More

Day 10 of your road trip in Italy is your departure day. This is your chance to catch a last glimpse of Rome before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, we recommend visiting Pantheon, a photogenic monument before you head out.

As your final day in Italy unfolds, enjoy a last-minute shopping spree in Rome's best shopping area, Galleria San Pietro. Enjoy finding the perfect gift or keepsake to remind you of your wonderful trip to Italy.

Before you conclude your road trip in Italy, drop by another restaurant for a last chance at a memorable dining experience in Rome.

Have a fantastic dining experience at Sofitel Roma Villa Borghese, a highly recommended choice for tonight's dinner. If you're looking to mix things up, Centro offers an enticing alternative with its varied menu.

You’ll then say farewell to Rome. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Italy!

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