11-Day Italy Self-Drive Road Trip With Itinerary from Perugia to Siena, Florence, and Rome and surrounding area
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Escape the ordinary with this exciting 11-day road trip through Italy. Explore the diverse landscapes, lively cities, and beyond. Pack your bags, hit the road, and prepare for an unforgettable journey!
This perfectly planned road trip itinerary in Italy takes you through some of the best places to see in the country. You will spend 3 nights in Perugia, 2 nights in Siena, 3 nights in Florence, and 2 nights in Rome. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!
With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Italy. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have got you covered.
Upon arriving in Perugia, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Italy on your own terms.
An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Italy. Trevi Fountain and Colosseum are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Pantheon, learn more about the unique Piazza Navona, and immerse yourself in the vibrant atmosphere of St. Peter's Basilica.
As you hit the open road and drive through Perugia, Santa Maria degli Angeli, Siena, Castellina in Chianti, Florence, Pisa, Lucca, Rome, and Orvieto, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Italy. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Italy.
Throughout your road trip in Italy, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Italy.
This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodation, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.
The best services in Italy fill up quickly, so book your spot early. Select a date and start planning your road trip in Italy today!
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Day 1
- Perugia - Arrival day
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- Piazza IV Novembre
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Say hello to Perugia! Your exciting road trip through Italy is just about to start. Navigating the top places to see in the region is a breeze with a car. The rental vehicle of your choice will be ready for pickup upon your arrival in the city. You will stay in Perugia for 2 nights before you continue your adventure!
Perugia is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Piazza Iv Novembre, or just taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.
Find your way to your hotel in Perugia. We recommend choosing a hotel in a central location for easy exploring. Check-in typically starts between 2 and 4 PM at hotels in Italy. Settle in and make plans for the evening.
As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Perugia, it's often a good idea to reserve a table in advance.
Savor the flavors at Ristorante Settimo Sigillo, a top pick for dinner tonight. Alternatively, Caffè Baglioni beckons with its unique menu offerings. Also, consider Bar Pellas. With its consistent customer satisfaction, it’s an excellent option for dining in Perugia tonight.
To truly maximize your evening out, consider visiting Tommi Bar after dinner. This bar is known for offering some of the best drinks and vibes in the city. Alternatively, head to Valentina, another bar with an inviting ambiance. Similarly, Caffe Dal Perugino also offers a great atmosphere, ensuring a night filled with enjoyment and relaxation.
Raise a toast to the start of your 11-day road trip in Italy!
Day 2
- Perugia
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Drive 54 km, 1 hour 40 min
- National Archaeological Museum of Umbria
- Basilica of San Francesco d'Assisi
- Pinacoteca Comunale Palazzo Vallemani
- Portico of Monte Frumentario
- Rocca Maggiore
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Wake up to day 2 of your extraordinary road trip in Italy. With 1 night left in Perugia, we encourage you to seize the day and discover the unexplored beauty of the city’s surroundings!
Perugia is brimming with adventures. Today’s wonderful stops include a museum, a church, an art gallery, a historical landmark, a castle and much more! Begin your sightseeing adventure at the curiosity-inducing National Archaeological Museum Of Umbria and allow yourself time to explore. Just a short distance away you'll find your next stop, Basilica Of San Francesco D'assisi, a culturally significant church that draws visitors from far and near.
Continue your journey to Pinacoteca Comunale Palazzo Vallemani, one of the city’s most often recommended spots that you shouldn’t miss. Another great site to visit is the curiosity-inducing Portico Of Monte Frumentario. When you're finished at the historical landmark, Rocca Maggiore awaits your visit. This castle is a history-steeped highlight on today's itinerary.
When you’re done exploring for the day, you’ll return to Perugia and your accommodation.
After a day of adventure, treat yourself to an exquisite dinner at one of Perugia's best restaurants.
Have a fantastic dining experience at La Taverna, a highly recommended choice for tonight's dinner. If you're looking to mix things up, Ristorante del Sole offers an enticing alternative with its varied menu. Additionally, Al Mangiar Bene is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Perugia.
Extend your evening after a delightful meal by visiting Caffè Fortebraccio, which offers the perfect atmosphere for a night out. Moreover, Caffe Del Banco is another popular option for a drink or two. Likewise, Dempsey's Perugia also provides a great ambiance for reminiscing about the day and raising a toast to your vacation.
Head back to your accommodation in Perugia and get some rest in preparation for another magical day of your road trip in Italy!
Day 3
- Perugia
- Siena
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Drive 107 km, 1 hour 38 min
- Pubblico Palace
- Tower of Mangia
- piazza del Campo
- Siena Cathedral
- Piccolomini Library
- Battistero di San Giovanni Battista
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Dive into day 3 of your remarkable road trip in Italy. Today you will explore Siena, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Siena. You’ll stay here for 2 nights.
Whether you prefer a leisurely exploration or a more fast-paced adventure, this itinerary in Perugia allows for both. Start by heading to Pubblico Palace. This curiosity-inducing palace provides an insightful glimpse into the city's identity. Next, discover Tower Of Mangia, an UNESCO world heritage-designated monument, promising a delightful encounter.
Continue your sightseeing with a visit to Piazza Del Campo, an impressive public square. When you’re done, don’t forget to make a stop at the well-known Siena Cathedral. Not far away from the church, you will find the culturally significant Battistero Di San Giovanni Battista, perfect for a quick visit. Round off your day at Piccolomini Library, another gem in Perugia with heritage-rich features to discover.
When you’re done exploring for the day, you’ll drive to your hotel in Siena. Check in and spend some time relaxing before you head out to tour the city.
As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Siena. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.
Enjoy a delicious meal at Enoteca I Terzi, a highly-rated dining destination in Siena. If you're eager to try something different, consider Ristorante Tar-Tufo, another top spot with a tantalizing menu. You might also want to secure a reservation at Antica Trattoria Papei. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Siena this evening.
After your delicious meal, get a taste of the vibrant nightlife with a visit to Meet Life Cafè, known for its inviting atmosphere. Maudit Pub is another great option if you’re looking for a place to get the night started. Similarly, Bar Impero Siena provides a great setting to enjoy the night away.
Get a good night's sleep and look forward to another great day on the road in Italy!
Day 4
- Siena
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Drive 76 km, 1 hour 52 min
- Basilica of San Domenico
- Rocca di Castellina in Chianti
- Castello di Brolio
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On day 4 of your road trip, you’ll start and end your day in Siena, where you'll stay for 1 night more.
Today's adventure in Siena promises more breathtaking discoveries and enriching experiences! Begin at Basilica Of San Domenico. This symbolic church is a highlight of any visit in the city. Then, enjoy Rocca Di Castellina In Chianti, another visually striking attraction that never fails to captivate visitors. Next, head over to Castello Di Brolio, one of the city’s most often recommended attractions, known for its visually striking features.
When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Siena.
As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Siena. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.
Make sure to reserve a table at Osteria Quattro Venti, an iconic dining spot in Siena. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Fischi per Fiaschi, a popular restaurant in Siena. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Osteria da Divo, a hidden gem nestled in Siena. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.
After savoring a delicious meal, step into the vibrant nightlife at Charlie Mixology Bar Di Aldinucci Riccardo, where the evening is just getting started. In the same way, Bar Pinacoteca offers a unique charm perfect for experiencing the local bar scene in Siena. San Paolo Pub is another top-recommended bar that is sure to get you into the mood for some dancing and celebrating.
Celebrate another amazing day of your road trip adventure in Italy!
Day 5
- Siena
- Florence
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Drive 75 km, 1 hour 42 min
- piazzale Michelangelo
- Basilica of Santa Croce in Florence
- Uffizi Gallery
- Ponte Vecchio
- Palazzo Vecchio
- piazza della Signoria
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Embark on another extraordinary experience on day 5 of your road trip in Italy. Today, you will make 1 stop and experience some of the highlights of Florence. At the end of the day, you will enjoy the comforts of a top-rated hotel in Florence, which will be your home away from home for 3 nights.
Today’s agenda in Siena includes an observation deck, a church, an art gallery, a historical landmark, a palace, a public square and much more! Piazzale Michelangelo is must-visit observation deck and a great starting point for the day. Next, continue your journey to Basilica Of Santa Croce In Florence, a popular church, located just a leisurely stroll away. Next, head to Uffizi Gallery, an eye-catching art gallery, also available for your discovery today.
Each stop on today’s itinerary promises to leave you with lasting memories and a deeper appreciation for Siena. When you're ready, let your sightseeing route take you to the timeless Ponte Vecchio. If you’re looking for more, Palazzo Vecchio is also an interesting attraction that is worthwhile a visit. Lastly, don’t miss Piazza Della Signoria, a place of grand interest in the city.
After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Florence. Florence offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.
After a day of adventure, treat yourself to an exquisite dinner at one of Florence's best restaurants.
Have a fantastic dining experience at Ristorante Oliviero 1962, a highly recommended choice for tonight's dinner. If you're looking to mix things up, Di Poneta Novoli offers an enticing alternative with its varied menu. Additionally, Caffe San Firenze is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Florence.
Keep the evening going at Manifattura, a great choice for enjoying the after-dinner hours with a drink. You could also go to Se·sto On Arno Rooftop Bar, which offers a similarly pleasant setting and great drinks. Another option is Il Vinile, which provides an inviting environment for unwinding after a busy day out.
Raise your glass to another unforgettable day in Italy!
Day 6
- Florence
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Drive 2 km, 30 min
- David
- Galleria dell'Accademia
- Cathedral of Santa Maria del Fiore
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On day 6 of your road trip, you will have an entire day to explore Florence. You’ll stay in Florence for 2 nights and discover all the best things to see and do in the area.
Florence is home to plenty of attractions that offer family-friendly attractions, photo-friendly spots, and history-rich sites! Start at David, a well-known statue that is worthwhile a visit in the city. Nearby, you’ll find Galleria Dell'accademia, enchanting visitors with its history-steeped appeal. Continue your exploration at Cathedral Of Santa Maria Del Fiore. This church is one of the city’s most spectacular spots.
Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.
As dinnertime approaches, it's time to head out for a bite to eat in Florence. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.
Savor the flavors at Ditta Artigianale, a top pick for dinner tonight. Alternatively, Trattoria Da Burde beckons with its unique menu offerings. Also, consider Casa Toscana. With its consistent customer satisfaction, it’s an excellent option for dining in Florence tonight.
Round off your dining experience by visiting Bar 50 Rosso, a prime location for a drink. Alternatively, explore the distinctive characteristics of Bitter Bar, a bar catering to every mood and preference. Archea Brewery likewise offers a unique atmosphere, perfect for a memorable night out.
As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in in Italy.
Day 7
- Florence
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Drive 199 km, 3 hours 12 min
- Piazza del Duomo, Pisa
- Pisa Cathedral
- Leaning Tower of Pisa
- Guinigi Tower
- Piazza dell'Anfiteatro
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On day 7 of your road trip in Italy, you’ll start and end your day in Florence, but spend the day exploring what’s beyond the city. Since you will return to Florence for 1 night more, there’s no need to rush. Experience Pisa and Lucca to the fullest today with this curated day itinerary!
Today’s itinerary in Florence covers several incredible sights, including a public square, a church, and a monument. Start your adventure at Piazza Del Duomo, Pisa. This world-famous public square is a place that is appreciated by travelers and locals alike. Next, immerse yourself in the picture-perfect wonders of Pisa Cathedral, a must-see church in the city.
Consider stopping for a small bite to eat or a drink at a local eatery to keep your energy going. When you’re ready, continue your discovery with a visit to Leaning Tower Of Pisa. This iconic monument offers an enriching experience. For a change of pace, head to Guinigi Tower, where you can take in grand features. Conclude your self-guided sightseeing tour with a visit to Piazza Dell'anfiteatro. These sights offer a fulfilling end to a perfect day.
When you’re done exploring for the day, you’ll return to Florence and your accommodation.
After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Florence. Enjoy a satisfying meal that will recharge you for tonight's adventures.
Treat yourself to a wonderful meal at Ristorante Buca Mario, a top-rated dining spot in Florence. If you're in the mood for something new, try Agricola Toscana, another premier location with a delectable menu. You might also want to book a table at Eataly Firenze. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Florence.
Let the evening flow smoothly from dinner to drinks at Gosh*, a top-rated bar in the area. For other recommendations, Antico Caffè Del Moro - Art Bar Firenze provides a perfect setting for rounding out your night with style and great drinks. Likewise, Quelo Bar offers a memorable night with diverse drink options and excellent service.
Raise your glass and celebrate another amazing day of your road trip in Italy!
Day 8
- Florence
- Rome
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Drive 283 km, 3 hours 57 min
- Colosseum
- Roman Forum
- Spanish Steps
- Piazza di Spagna
- Trevi Fountain
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On day 8 of your road trip in Italy, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Rome. In the evening, you’ll end up in Rome, where you will stay for 2 nights.
Discover a day packed with fun adventures, scenic views, and picturesque spots in Florence. Begin your sightseeing with Colosseum. This globally renowned archeological site is one of the top attractions in the city. Proceed to Roman Forum, another must-visit attraction.
As you wander through the inviting streets of Florence, soak in the lively ambiance and take the opportunity to snap some photos. Next, head to Spanish Steps. This impressive public square is a traveler-favorite. Not far away, you’ll find Piazza Di Spagna, another key site on your sightseeing itinerary. Trevi Fountain is yet another highly recommended place to visit nearby, offering plenty to discover for curious travelers.
At the end of the day, you will drive to Rome, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.
As you explore more of Rome, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.
Treat yourself to a delightful dinner at La Bottega Roma, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Pasta In Corso? It's another excellent option with a diverse menu. Consider reserving a table at Trattoria Vecchia Roma as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Rome.
Explore the vibrant nightlife at La Botticella Of Poggi Giovanni after your meal, a hub for lively evenings and memorable moments. Or, head to Almalu Trastevere for a great selection of flavorful drinks and a charming setting. Furthermore, Bar Viminale Di Pepi Maurilio is perfect for those looking to extend their night with a touch of local flavor.
Savor another day of unforgettable experiences in Italy!
Day 9
- Rome
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Drive 9 km, 1 hour 9 min
- Vatican Museums
- Saint Peter's Square
- Sistine Chapel
- St Peter's Basilica
- Piazza Navona
- Pantheon
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Greet day 9 of your road trip in Italy with a smile and start your day with a hearty breakfast. You will return to Rome for your remaining 1 night in the city later today, but first, it’s time for some exploring! On the agenda for this day, you’ll find only the best things to see and do in Vatican City and Rome.
Get ready for a day filled with fun adventures, romantic experiences, and scenic views in the charming city of Rome. Your adventure starts at Vatican Museums, an iconic local hot spot. Another notable attraction to explore is Saint Peter's Square.
After soaking in the highlights of these sights, take some time to wander Rome's streets and immerse yourself in the local atmosphere. When you're ready to continue your sightseeing adventure, head to Sistine Chapel. St. Peter's Basilica is also worth visiting, along with Piazza Navona. These standout landmarks offer unique experiences that add to the day’s enjoyment. End your day at Pantheon. This iconic monument provides a fitting finale to your sightseeing.
When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Rome.
As dinnertime approaches, it's time to head out for a bite to eat in Rome. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.
Enjoy a lovely dining experience at RomAntica, a popular restaurant in Rome. This acclaimed establishment has earned the admiration of countless food lovers in the city. Alternatively, experience a taste of Rome at Coso Ristorante, another great place to eat. With a menu designed to impress, it promises a journey of flavors that will leave you captivated. A third option to check out is the top-rated DEROMA - Farine Romane. It’s yet another ideal choice to enhance your time in Rome tonight.
Keep the evening going at Sant' Eustachio Caffè, a great choice for enjoying the after-dinner hours with a drink. You could also go to Yellowsquare Rome, which offers a similarly pleasant setting and great drinks. Another option is Caffè Portofino, which provides an inviting environment for unwinding after a busy day out.
Raise your glass to another unforgettable day in Italy!
Day 10
- Rome
- Perugia
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Drive 202 km, 3 hours 9 min
- Orvieto Cathedral
- Orvieto subterranea
- Torre del Moro Orvieto
- Pozzo della Cava
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On day 10 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 1 destination, Orvieto. When you’re not sightseeing, take time to relax at your selected hotel in Perugia, where you’ll be staying for 1 night.
Today’s well-planned self-sightseeing route offers several fun adventures, romantic experiences, and breathtaking views. Whether you decide to explore Rome on foot, use public transport, or join a guided tour, there are a few attractions you don’t want to miss. Orvieto Cathedral is the first of them. Spend some time admiring this romantic church before continuing your journey. Orvieto Underground is your next stop. This worthwhile cave system is one of the best-rated sights in Rome.
Consider grabbing some lunch or a light snack to keep your energy going. Beyond the above-mentioned attractions, today is also the perfect time to visit Torre Del Moro Orvieto. This respected monument is a sight to behold. To round off your sightseeing experience, visit Pozzo Della Cava.
When you’re done exploring for the day, you’ll drive to your hotel in Perugia. Check in and spend some time relaxing before you head out to tour the city.
Indulge in a memorable dining experience at one of Perugia's most popular restaurants, and connect with friendly locals for an authentic adventure.
Dine in style at Perugia Plaza Hotel, a top recommendation for dinner tonight. Or, for a change of pace, Elfo Pub Perugia boasts a menu that's sure to impress. Also, be sure to check out Sangallo Palace Hotel. Known as a local hotspot, it’s a great choice for tonight in Perugia.
Unwind after your meal by stepping into Il Birrino. This venue is celebrated for its extensive drink selections and cozy vibes. Alternatively, Quei Bravi Ragazzi offers a dynamic and energetic atmosphere for a glass or two. Don’t overlook Lo Chalet - Lounge Bar, another top-rated bar in the area.
Say good night to Perugia and look forward to another great day of your road trip in Italy!
Day 11
- Perugia - Departure day
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- Etruscan Arch
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Day 11 of your road trip in Italy is your departure day. This is your chance to catch a last glimpse of Perugia before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.
If you're up for some more sightseeing, we recommend visiting Etruscan Arch, a culturally significant historical landmark before you head out.
Make the most of your final day in Italy by visiting Perugia’s iconic markets and shopping establishments. Secure the perfect souvenirs for your family and friends back home or buy yourself a remembrance of your amazing experience in Italy.
Before you conclude your road trip in Italy, drop by another restaurant for a last chance at a memorable dining experience in Perugia.
If you're in the mood to try something new, consider Osteria a Priori, another top spot with a mouthwatering menu.
You’ll then say farewell to Perugia. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Italy!
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