13-Day Italy Self-Drive Road Trip With Itinerary from Florence traveling south to Siena, Perugia, Rome, Naples, and Amalfi

Day 2 offers a multitude of experiences. You will stay in Florence for 2 nights more, offering you enough time to explore at a relaxed pace.

Get ready for an exciting day in Florence. Today’s sightseeing agenda includes an art gallery, a public square, a historical landmark, a church, an observation deck and much more! Begin your adventure at Galleria Dell'accademia. This is a popular art gallery you should not miss. Another must-see is Piazza Della Signoria, an extraordinary public square in Florence.

When you’re ready for the next sight, head to Ponte Vecchio. From there, take a leisurely stroll to Uffizi Gallery, another of the city’s top-rated attractions. We recommend continuing your self-guided tour at Basilica Of Santa Croce In Florence, a photogenic place of interest in the city. If time allows, add Piazzale Michelangelo to your itinerary. This widely recognized observation deck offers the perfect finishing touch to your day in Florence.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Florence. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Enjoy a lovely meal at Ditta Artigianale, a top-rated place to have dinner tonight. Alternatively, if your taste buds call for something different, Trattoria Da Burde is another top choice with a popular menu. You could also check for a table at Casa Toscana. As an establishment that gains consistently high praises from customers, it’s an ideal choice in Florence tonight.

Continue your evening by exploring the vibrant nightlife scene at Bar 50 Rosso, a prime destination for a thrilling night out. Also, don’t forget to check out Bitter Bar, a bar that offers unique local touches. Likewise, Archea Brewery provides an excellent alternative for a fun evening.

Head back to your accommodation in Florence and get some rest in preparation for another magical day of your road trip in Italy!

Wake up to day 3 of your extraordinary road trip in Italy. With 1 night left in Florence, we encourage you to seize the day and discover the unexplored beauty of the city’s surroundings!

Get ready to discover some of the most iconic wonders in Florence, including a public square, a monument, and a historical landmark. Start your day at Piazza Del Duomo, Pisa. This UNESCO world heritage-listed public square is a wondrous place to see in Florence. Then, wander over to Leaning Tower Of Pisa. If UNESCO world heritage-designated sites excite you, this monument will be right up your alley. Nearby, you’ll also find Piazza Dell'anfiteatro. This romantic public square is a favorite among visitors.

Florence offers plenty to explore, ensuring every moment of your visit is filled with excitement and discovery. If you're up for more, Guinigi Tower is a locally appreciated spot in the city that will captivate you with its unique charm. When you’re done at the monument, don’t forget to check out the symbolic Mura Di Lucca. Take a moment to appreciate the fascinating details of this worthwhile historical landmark.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Florence.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Florence. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Savor the flavors at Ristorante Buca Mario, a top pick for dinner tonight. Alternatively, Agricola Toscana beckons with its unique menu offerings. Also, consider Eataly Firenze. With its consistent customer satisfaction, it’s an excellent option for dining in Florence tonight.

Unwind after your meal by stepping into Gosh*. This venue is celebrated for its extensive drink selections and cozy vibes. Alternatively, Antico Caffè Del Moro - Art Bar Firenze offers a dynamic and energetic atmosphere for a glass or two. Don’t overlook Quelo Bar, another top-rated bar in the area.

Say good night to Florence and look forward to another great day of your road trip in Italy!

On day 4 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 2 destinations, Siena and San Gimignano. When you’re not sightseeing, take time to relax at your selected hotel in Siena, where you’ll be staying for 2 nights.

Today’s agenda in Florence includes a church, a public square, a monument, a museum and much more! Siena Cathedral is must-visit church and a great starting point for the day. Next, continue your journey to Piazza Del Campo, a widely recognized public square, located just a leisurely stroll away. Next, head to Tower Of Mangia, a picture-perfect monument, also available for your discovery today.

Each stop on today’s itinerary promises to leave you with lasting memories and a deeper appreciation for Florence. When you're ready, let your sightseeing route take you to the curiosity-inducing Chiesa Di Sant'agostino. If you’re looking for more, Palazzo Comunale, Pinacoteca, Torre Grossa is also a frequently visited attraction that is worthwhile a visit. Lastly, don’t miss Piazza Del Duomo, a place of enchanting interest in the city.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Siena. Siena offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

As you explore more of Siena, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Enjoy a delicious meal at Enoteca I Terzi, a top-rated dining destination in Siena. If you're in the mood to try something new, consider Ristorante Tar-Tufo, another top spot with a mouthwatering menu. You might also want to secure a reservation at Antica Trattoria Papei. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Siena this evening.

Continue your lively evening at Meet Life Cafè, a perfect place for winding down or revving up the night, depending on which mood you’re in. Maudit Pub is another excellent bar that offers a great selection of drinks to suit any mood. If you prefer to go somewhere else, Bar Impero Siena ensures a night out tailored to your taste.

Relax and recharge in preparation for another adventurous day in Italy!

At the end of the day, you'll drive back to Siena, where you'll stay for 1 night more.

Today’s agenda in Siena includes a sculpture garden, a castle, and an astronomical observatory. Parco Sculture Del Chianti is must-visit sculpture garden and a great starting point for the day. Next, continue your journey to Castello Di Brolio, an often recommended castle, located just a leisurely stroll away. Next, head to Rocca Di Castellina In Chianti, an enchanting castle, also available for your discovery today.

When you’re done exploring for the day, you’ll return to Siena and your accommodation.

As dinnertime approaches, it's time to head out for a bite to eat in Siena. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Enjoy a lovely dining experience at Osteria Quattro Venti, a popular restaurant in Siena. This acclaimed establishment has earned the admiration of countless food lovers in the city. Alternatively, experience a taste of Siena at Fischi per Fiaschi, another great place to eat. With a menu designed to impress, it promises a journey of flavors that will leave you captivated. A third option to check out is the top-rated Osteria da Divo. It’s yet another ideal choice to enhance your time in Siena tonight.

Round off your dining experience by visiting Charlie Mixology Bar Di Aldinucci Riccardo, a prime location for a drink. Alternatively, explore the distinctive characteristics of Bar Pinacoteca, a bar catering to every mood and preference. San Paolo Pub likewise offers a unique atmosphere, perfect for a memorable night out.

Take some time to reflect on your day and savor another beautiful night in Italy.

Embark on another extraordinary experience on day 6 of your road trip in Italy. Today, you will make 2 stops and experience some of the highlights of Santa Maria degli Angeli and Perugia. At the end of the day, you will enjoy the comforts of a top-rated hotel in Perugia, which will be your home away from home for 1 night.

Today's adventure in Siena promises more breathtaking discoveries and enriching experiences! Begin at Chiesa Nuova Di San Francesco Convertito. This standout church is a highlight of any visit in the town. Then, enjoy Rocca Maggiore, another symbolic attraction that never fails to captivate visitors. Next, head over to Basilica Of San Francesco D'assisi, one of the town’s most notable attractions, known for its stunning features.

If you’re looking for more, spend time soaking in the atmosphere of Rocca Paolina. This instagrammable historical landmark is frequented by locals and tourists alike. To complete your memorable day, make sure to visit Perugia Sotterranea Accesso, a curiosity-inducing cave system, and take a stroll around the area. If you want to extend your self-guided sightseeing tour, go check out Piazza Iv Novembre before you head back to your hotel.

At the end of the day, you will drive to Perugia, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

After a day of adventure, treat yourself to an exquisite dinner at one of Perugia's best restaurants.

Savor the flavors at Ristorante Settimo Sigillo, a top pick for dinner tonight. Alternatively, Caffè Baglioni beckons with its unique menu offerings. Also, consider Bar Pellas. With its consistent customer satisfaction, it’s an excellent option for dining in Perugia tonight.

Following your dinner, dive into the local bar culture at Tommi Bar. Enjoy this evening's relaxed ambiance with delightful drinks. Alternatively, go to Valentina, the perfect place for those looking to experience the best of the nightlife. Similarly, Caffe Dal Perugino provides excellent drinks and a great atmosphere, ensuring a memorable night out.

Savor another day of unforgettable experiences in Italy!

Dive into day 7 of your remarkable road trip in Italy. Today you will explore Orvieto, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Rome. You’ll stay here for 3 nights.

Get ready for a day filled with family-friendly attractions, romantic experiences, and breathtaking views in the charming town of Perugia. Your adventure starts at Orvieto Cathedral, an interesting local hot spot. Another notable attraction to explore is Museo Dell'opera Del Duomo. This worthwhile museum is known for its majestic appeal.

After soaking in the highlights of these sights, take some time to wander Perugia's streets and immerse yourself in the local atmosphere. When you're ready to continue your sightseeing adventure, head to Orvieto Underground. This historic cave system offers a fascinating experience that many visitors find memorable.

When you’re done exploring for the day, you’ll drive to your hotel in Rome. Check in and spend some time relaxing before you head out to tour the city.

As dinnertime approaches, it's time to head out for a bite to eat in Rome. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Make sure to reserve a table at La Bottega Roma, an iconic dining spot in Rome. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Pasta In Corso, a popular restaurant in Rome. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Trattoria Vecchia Roma, a hidden gem nestled in Rome. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

To truly maximize your evening out, consider visiting La Botticella Of Poggi Giovanni after dinner. This bar is known for offering some of the best drinks and vibes in the city. Alternatively, head to Almalu Trastevere, another bar with an inviting ambiance. Similarly, Bar Viminale Di Pepi Maurilio also offers a great atmosphere, ensuring a night filled with enjoyment and relaxation.

As the sun sets on another day of adventure, rest up and recharge for the next leg of your road trip in Italy.

On day 8 of your road trip in Italy, you’ll start and end your day in Rome, but spend the day exploring what’s beyond the city. Since you will return to Rome for 2 nights more, there’s no need to rush. Experience Rome and Vatican City to the fullest today with this curated day itinerary!

Today's adventure in Rome promises more breathtaking discoveries and enriching experiences! Begin at Colosseum. This breathtaking archeological site is a highlight of any visit in the city. Then, enjoy Roman Forum, another picture-perfect attraction that never fails to captivate visitors. Next, head over to Trevi Fountain, one of the city’s most timeless attractions, known for its visually striking features.

If you’re looking for more, spend time soaking in the atmosphere of Pantheon. This culturally significant monument is frequented by locals and tourists alike. To complete your memorable day, make sure to visit Piazza Navona, a wondrous public square, and take a stroll around the area. If you want to extend your self-guided sightseeing tour, go check out St. Peter's Basilica before you head back to your hotel.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Rome.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Rome. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Treat yourself to a wonderful meal at RomAntica, a top-rated dining spot in Rome. If you're in the mood for something new, try Coso Ristorante, another premier location with a delectable menu. You might also want to book a table at DEROMA - Farine Romane. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Rome.

Cap off your dinner by heading to Sant' Eustachio Caffè, ideal for a leisurely evening with a drink in hand. Yellowsquare Rome is another bar that offers an enjoyable setting. Similarly, Caffè Portofino is also a popular place to go on a night out, perfect for relaxing and socializing.

Savor another day of unforgettable experiences in Italy!

Greet day 9 of your road trip in Italy with a smile and start your day with a hearty breakfast. You will return to Rome for your remaining 1 night in the city later today, but first, it’s time for some exploring! On the agenda for this day, you’ll find only the best things to see and do in Tivoli.

Today, you'll explore some of the most beautiful places in Rome, including an archeological site, a palace, a monument, a park, a waterfall and much more! Start your day with a visit to Hadrian's Villa. This worthwhile archeological site is a must-visit in the town. When you’re ready for your next discovery, continue to Villa D'este, which may be one of the most visually striking places you will experience today.

One of the best things about exploring Rome on a self-guided tour is that you set the pace. There’s plenty of time for detours and discovering hidden gems. When you’re ready for your next stop, make your way to Fontana Dell'organo, a locally appreciated monument in the town. If you’re up for more discoveries, don’t forget to reserve some time for Gregorian Bridge and Villa Gregoriana. End your day with a visit to Grande Cascata Di Tivoli, an intriguing waterfall that’s sure to leave a lasting impression.

When you’re done exploring for the day, you’ll return to Rome and your accommodation.

Indulge in a memorable dining experience at one of Rome's most popular restaurants, and connect with friendly locals for an authentic adventure.

Enjoy a delicious meal at Hotel de Russie, a highly-rated dining destination in Rome. If you're eager to try something different, consider La Taverna Italiana, another top spot with a tantalizing menu. You might also want to secure a reservation at The Parrot Bar. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Rome this evening.

After your delicious meal, get a taste of the vibrant nightlife with a visit to The Apartment Bar Roma, known for its inviting atmosphere. Hotel Hassler Roma is another great option if you’re looking for a place to get the night started.

Raise your glass and celebrate another amazing day of your road trip in Italy!

On day 10 of your road trip in Italy, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Naples. In the evening, you’ll end up in Naples, where you will stay for 1 night.

Immerse yourself in Rome’s rich culture with today's sightseeing itinerary. Start your journey at Castel Sant'elmo. This historic castle is sure to ignite your curiosity. Next, dive into the photogenic features of Naples National Archaeological Museum, a must-visit museum in the city.

In between sights, stop by local stores, picturesque photo spots, and small eateries. When you’re ready for your next attraction, proceed to Cappella Sansevero, a popular museum. For a change of scene, check out Spaccanapoli, known for its romantic features.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Naples. Naples offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

Indulge in a memorable dining experience at one of Naples's most popular restaurants, and connect with friendly locals for an authentic adventure.

Make sure to reserve a table at L'Oca Nera Irish Pub, an iconic dining spot in Naples. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Mimì alla Ferrovia, a popular restaurant in Naples. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Spuzzulè Winebar, a hidden gem nestled in Naples. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Continue your evening by exploring the vibrant nightlife scene at Happening Cocktail Bar, a prime destination for a thrilling night out. Also, don’t forget to check out Shanti Art Musik Bar, a bar that offers unique local touches. Likewise, Gran Caffè Gambrinus provides an excellent alternative for a fun evening.

Say good night to Naples and look forward to another great day of your road trip in Italy!

Experience an unparalleled adventure on day 11 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 4 vibrant destinations - Ottaviano, Pompei, Ravello, and Amalfi. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Amalfi. You will spend 1 night here for some well-deserved relaxation.

Enjoy the perfect balance of relaxation and exploration in Naples today. One of the most worthwhile attractions included on the itinerary is Mount Vesuvius. This instagrammable volcano will help you start your sightseeing on top. Then, take a leisurely stroll to Archaeological Park Of Pompeii and learn what makes this UNESCO world heritage-designated archeological site unique.

Throughout the day, make sure to take breaks to appreciate the surroundings. Next up, visit the up-and-coming Lupanare Di Pompei. After exploring the archeological site, head to Villa Rufolo. This popular historical landmark is a highlight in Naples.

At the end of the day, you will drive to Amalfi, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Amalfi. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Dine in style at Pasticceria Pansa Amalfi, a top recommendation for dinner tonight. Or, for a change of pace, Grand Hotel Excelsior Amalfi boasts a menu that's sure to impress. Also, be sure to check out Lido Azzurro. Known as a local hotspot, it’s a great choice for tonight in Amalfi.

Round off your dining experience by visiting Bar Della Valle, a prime location for a drink.

Get a good night's sleep and look forward to another great day on the road in Italy!

On day 12 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 1 destination, Orvieto. When you’re not sightseeing, take time to relax at your selected hotel in Florence, where you’ll be staying for 1 night.

Savor the day by visiting some of the best places to see in Amalfi, including a monument and a cave. Start your adventure at Well Of St. Patrick. This popular monument is a must-visit for travelers looking for a unique holiday experience. Make your way to Torre Del Moro Orvieto located in Amalfi for another exciting encounter.

Next, immerse yourself in the setting of Pozzo Della Cava. Its photogenic features will captivate you.

When you’re done exploring for the day, you’ll drive to your hotel in Florence. Check in and spend some time relaxing before you head out to tour the city.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Florence. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Enjoy a lovely dining experience at Tijuana, a popular restaurant in Florence. This acclaimed establishment has earned the admiration of countless food lovers in the city. Alternatively, experience a taste of Florence at Djària - American Bar, another great place to eat. With a menu designed to impress, it promises a journey of flavors that will leave you captivated. A third option to check out is the top-rated The Florence Irish Pub. It’s yet another ideal choice to enhance your time in Florence tonight.

Head back to your accommodation in Florence and get some rest in preparation for another magical day of your road trip in Italy!