13-Day Italy Self-Drive Road Trip With Itinerary from Florence traveling south to Siena, Perugia, Rome, Naples, and Amalfi

Day 2 of your road trip will take you to the best attractions Florence has to offer. Cherish the 2 nights you have left in Florence by discovering the best things there are to see and do in the city.

Immerse yourself in Florence’s rich culture with today's sightseeing itinerary. Start your journey at Galleria Dell'accademia. This photogenic art gallery is sure to ignite your curiosity. Next, dive into the history-steeped features of Piazza Della Signoria, a must-visit public square in the city.

In between sights, stop by local stores, picturesque photo spots, and small eateries. When you’re ready for your next attraction, proceed to Ponte Vecchio, a wondrous historical landmark. For a change of scene, check out Uffizi Gallery, known for its picture-perfect features. We also recommend visiting Basilica Of Santa Croce In Florence. This church is a must for anyone looking to experience the city to the fullest. Lastly, end your day with a visit to Piazzale Michelangelo, yet another impressive attraction in Florence.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Florence. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Have a fantastic dining experience at Ditta Artigianale, a highly recommended choice for tonight's dinner. If you're looking to mix things up, Trattoria Da Burde offers an enticing alternative with its varied menu. Additionally, Casa Toscana is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Florence.

Continue your lively evening at Bar 50 Rosso, a perfect place for winding down or revving up the night, depending on which mood you’re in. Bitter Bar is another excellent bar that offers a great selection of drinks to suit any mood. If you prefer to go somewhere else, Archea Brewery ensures a night out tailored to your taste.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in in Italy.

Greet day 3 of your road trip in Italy with a smile and start your day with a hearty breakfast. You will return to Florence for your remaining 1 night in the city later today, but first, it’s time for some exploring! On the agenda for this day, you’ll find only the best things to see and do in Pisa and Lucca.

Savor the day by visiting some of the best places to see in Florence, including a public square, a monument, and a historical landmark. Start your adventure at Piazza Del Duomo, Pisa. This world-famous public square is a must-visit for travelers looking for a unique holiday experience. Make your way to Leaning Tower Of Pisa located in Florence for another exciting encounter.

Next, immerse yourself in the setting of Piazza Dell'anfiteatro. Its visually striking features will captivate you. After the public square, continue your tour of the city with a visit to Guinigi Tower. Visitors usually appreciate the history-steeped features of this monument. Next up is Mura Di Lucca, a highly recommended historical landmark.

When you’re done exploring for the day, you’ll return to Florence and your accommodation.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Florence. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Have a fantastic dining experience at Ristorante Buca Mario, a highly recommended choice for tonight's dinner. If you're looking to mix things up, Agricola Toscana offers an enticing alternative with its varied menu. Additionally, Eataly Firenze is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Florence.

Explore the vibrant nightlife at Gosh* after your meal, a hub for lively evenings and memorable moments. Or, head to Antico Caffè Del Moro - Art Bar Firenze for a great selection of flavorful drinks and a charming setting. Furthermore, Quelo Bar is perfect for those looking to extend their night with a touch of local flavor.

Take some time to reflect on your day and savor another beautiful night in Italy.

Dive into day 4 of your remarkable road trip in Italy. Today you will explore Siena and San Gimignano, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Siena. You’ll stay here for 2 nights.

A blend of fun adventures, romantic experiences, and breathtaking views await you in Florence on today’s itinerary. First up is the locally renowned church, Siena Cathedral. Afterward, continue to Piazza Del Campo, a public square every traveler should visit.

As you explore Florence’s charming streets, take in the lively atmosphere and get to know the character of the city. Next, make your way to Tower Of Mangia. This often recommended monument is an essential stop. Following that, head to Chiesa Di Sant'agostino, another must-visit site that will enhance your experience. Don’t forget to stop by Palazzo Comunale, Pinacoteca, Torre Grossa, an underrated museum in the city. Finally, end your day with a visit to Piazza Del Duomo, an inviting public square that offers the perfect conclusion to your sightseeing of the day.

When you’re done exploring for the day, you’ll drive to your hotel in Siena. Check in and spend some time relaxing before you head out to tour the city.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Siena. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Enjoy a lovely dining experience at Enoteca I Terzi, a popular restaurant in Siena. This acclaimed establishment has earned the admiration of countless food lovers in the city. Alternatively, experience a taste of Siena at Ristorante Tar-Tufo, another great place to eat. With a menu designed to impress, it promises a journey of flavors that will leave you captivated. A third option to check out is the top-rated Antica Trattoria Papei. It’s yet another ideal choice to enhance your time in Siena tonight.

Explore the vibrant nightlife at Meet Life Cafè after your meal, a hub for lively evenings and memorable moments. Or, head to Maudit Pub for a great selection of flavorful drinks and a charming setting. Furthermore, Bar Impero Siena is perfect for those looking to extend their night with a touch of local flavor.

Say good night to Siena and look forward to another great day of your road trip in Italy!

On day 5 of your road trip in Italy, you’ll start and end your day in Siena, but spend the day exploring what’s beyond the city. Since you will return to Siena for 1 night more, there’s no need to rush. Experience Pievasciata, San Regolo, Castellina in Chianti, and San Donato in Poggio to the fullest today with this curated day itinerary!

Siena is home to plenty of attractions that offer family-friendly attractions, romantic experiences, and scenic views! Start at Parco Sculture Del Chianti, an up-and-coming sculpture garden that is worthwhile a visit in the hamlet. Nearby, you’ll find Castello Di Brolio, enchanting visitors with its enchanting appeal. Continue your exploration at Rocca Di Castellina In Chianti. This castle is one of the hamlet’s most worthwhile spots.

Enjoy the freedom of exploring Siena at your own pace and find hidden gems along the way. If you want to see more picture-perfect spots, make sure to visit Osservatorio Polifunzionale Del Chianti.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Siena.

Indulge in a memorable dining experience at one of Siena's most popular restaurants, and connect with friendly locals for an authentic adventure.

Enjoy a delicious meal at Osteria Quattro Venti, a highly-rated dining destination in Siena. If you're eager to try something different, consider Fischi per Fiaschi, another top spot with a tantalizing menu. You might also want to secure a reservation at Osteria da Divo. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Siena this evening.

After enjoying a fulfilling meal, continue your evening at Charlie Mixology Bar Di Aldinucci Riccardo, ideal for those looking to unwind with a drink in a comfortable setting. Alternatively, Bar Pinacoteca offers a welcoming atmosphere for easing into the nightlife. Similarly, San Paolo Pub provides an excellent environment for a relaxed and enjoyable evening.

Get a good night's sleep and look forward to another great day on the road in Italy!

Experience an unparalleled adventure on day 6 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 2 vibrant destinations - Santa Maria degli Angeli and Perugia. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Perugia. You will spend 1 night here for some well-deserved relaxation.

Get ready for an exciting day in Siena. Today’s sightseeing agenda includes a church, a castle, a historical landmark, a cave system, a public square and much more! Begin your adventure at Chiesa Nuova Di San Francesco Convertito. This is a worthwhile church you should not miss. Another must-see is Rocca Maggiore, a worthwhile castle in Siena.

When you’re ready for the next sight, head to Basilica Of San Francesco D'assisi. From there, take a leisurely stroll to Rocca Paolina, another of the town’s intriguing attractions. We recommend continuing your self-guided tour at Perugia Sotterranea Accesso, a historic place of interest in the town. If time allows, add Piazza Iv Novembre to your itinerary. This underrated public square offers the perfect finishing touch to your day in Siena.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Perugia. Perugia offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

As you explore more of Perugia, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Enjoy a lovely meal at Ristorante Settimo Sigillo, a top-rated place to have dinner tonight. Alternatively, if your taste buds call for something different, Caffè Baglioni is another top choice with a popular menu. You could also check for a table at Bar Pellas. As an establishment that gains consistently high praises from customers, it’s an ideal choice in Perugia tonight.

After your meal, keep the night alive at a bar like Tommi Bar, known for its lively atmosphere. Valentina is another top recommendation that provides the perfect setting with well-crafted drinks and a welcoming ambiance. Similarly, Caffe Dal Perugino offers an excellent atmosphere for those looking to amp up the evening.

As the sun sets on another day of adventure, rest up and recharge for the next leg of your road trip in Italy.

Embark on another extraordinary experience on day 7 of your road trip in Italy. Today, you will make 1 stop and experience some of the highlights of Orvieto. At the end of the day, you will enjoy the comforts of a top-rated hotel in Rome, which will be your home away from home for 3 nights.

Today’s itinerary in Perugia covers several incredible sights, including a church, a museum, and a cave system. Start your adventure at Orvieto Cathedral. This popular church is a place that is appreciated by travelers and locals alike. Next, immerse yourself in the photogenic wonders of Museo Dell'opera Del Duomo, a must-see museum in the town.

Consider stopping for a small bite to eat or a drink at a local eatery to keep your energy going. When you’re ready, continue your discovery with a visit to Orvieto Underground. This locally appreciated cave system offers an enriching experience. These sights offer a fulfilling end to a perfect day.

At the end of the day, you will drive to Rome, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

After a day of adventure, treat yourself to an exquisite dinner at one of Rome's best restaurants.

Make sure to reserve a table at La Bottega Roma, an iconic dining spot in Rome. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Pasta In Corso, a popular restaurant in Rome. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Trattoria Vecchia Roma, a hidden gem nestled in Rome. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Cap off your dinner by heading to La Botticella Of Poggi Giovanni, ideal for a leisurely evening with a drink in hand. Almalu Trastevere is another bar that offers an enjoyable setting. Similarly, Bar Viminale Di Pepi Maurilio is also a popular place to go on a night out, perfect for relaxing and socializing.

Relax and recharge in preparation for another adventurous day in Italy!

On day 8 of your road trip, you’ll start and end your day in Rome, but spend part of the day exploring places of interest outside the immediate city. On today's itinerary, you'll find attractions in Rome and Vatican City. You still have 2 nights left in Rome.

Brace yourself for today’s incredible lineup of attractions in Rome, featuring fun adventures, scenic views, and picturesque spots. Start at Colosseum, a wondrous archeological site in the city. Then, head to Roman Forum and soak in the ambiance of this culturally significant archeological site.

There are many interesting places to see in Rome, and when you are ready for more, go to Trevi Fountain. This is one of the city’s most wondrous history-steeped spots of interest. After exploring the monument, visit the wondrous Pantheon. Not far away, you'll also find Piazza Navona. This public square is a romantic highlight in Rome. Before wrapping up your self-guided sightseeing tour, head to St. Peter's Basilica, a timeless major basilica in the city.

When you’re done exploring for the day, you’ll return to Rome and your accommodation.

After a day of adventure, treat yourself to an exquisite dinner at one of Rome's best restaurants.

Don’t miss out on dining at RomAntica, a top-rated dining destination in Rome. If you're in the mood to try something new, consider Coso Ristorante, another top spot with a mouthwatering menu. You might also want to secure a reservation at DEROMA - Farine Romane. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Rome this evening.

After savoring a delicious meal, step into the vibrant nightlife at Sant' Eustachio Caffè, where the evening is just getting started. In the same way, Yellowsquare Rome offers a unique charm perfect for experiencing the local bar scene in Rome. Caffè Portofino is another top-recommended bar that is sure to get you into the mood for some dancing and celebrating.

Say good night to Rome and look forward to another great day of your road trip in Italy!

Wake up to day 9 of your extraordinary road trip in Italy. With 1 night left in Rome, we encourage you to seize the day and discover the unexplored beauty of the city’s surroundings!

Bring your curiosity for today’s adventure around Rome. Some of the town’s most loved attractions await! Hadrian's Villa is the perfect place to start. This archeological site is one of the most intriguing places to visit in Rome. Next, head to Villa D'este, a well-known palace, known for its romantic features.

In between the sights, don’t hesitate to take small detours to explore local stores and eateries. When you’re ready to continue your adventure, head to Fontana Dell'organo. This visually striking monument is a highly recommended experience. Nearby, you'll also find Gregorian Bridge and Villa Gregoriana. Visit these for an interesting touch to your journey. Finish the day with a visit to Grande Cascata Di Tivoli, an eye-catching waterfall in Rome.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Rome.

As dinnertime approaches, it's time to head out for a bite to eat in Rome. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Treat yourself to a delicious dinner at Hotel de Russie, an excellent option for tonight's dining. Looking for something different? La Taverna Italiana offers a tantalizing alternative with its diverse menu. And don’t miss The Parrot Bar. With its reputation for pleasing customers, it’s a fantastic choice for tonight in Rome.

Continue your lively evening at The Apartment Bar Roma, a perfect place for winding down or revving up the night, depending on which mood you’re in. Hotel Hassler Roma is another excellent bar that offers a great selection of drinks to suit any mood.

Raise your glass and celebrate another amazing day of your road trip in Italy!

On day 10 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 1 destination, Naples. When you’re not sightseeing, take time to relax at your selected hotel in Naples, where you’ll be staying for 1 night.

Start by visiting Castel Sant'elmo, a prime spot to begin your journey. This historic castle is sure to impress. Next on your list is Naples National Archaeological Museum, another must-visit landmark and popular museum renowned for its heritage-rich features.

While exploring and sightseeing, take time to savor the culture of Rome by sampling some local delicacies. When you’re ready for more sightseeing, head to Cappella Sansevero. This detailed museum is an essential place to visit for anyone looking for the full Rome experience. We also recommend visiting Spaccanapoli, an intriguing street.

When you’re done exploring for the day, you’ll drive to your hotel in Naples. Check in and spend some time relaxing before you head out to tour the city.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Naples. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Enjoy a delicious meal at L'Oca Nera Irish Pub, a top-rated dining destination in Naples. If you're in the mood to try something new, consider Mimì alla Ferrovia, another top spot with a mouthwatering menu. You might also want to secure a reservation at Spuzzulè Winebar. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Naples this evening.

Let the evening flow smoothly from dinner to drinks at Happening Cocktail Bar, a top-rated bar in the area. For other recommendations, Shanti Art Musik Bar provides a perfect setting for rounding out your night with style and great drinks. Likewise, Gran Caffè Gambrinus offers a memorable night with diverse drink options and excellent service.

Get a good night's sleep and look forward to another great day on the road in Italy!

On day 11 of your road trip in Italy, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Ottaviano, Pompei, Ravello, and Amalfi. In the evening, you’ll end up in Amalfi, where you will stay for 1 night.

Set out on a day brimming with fun adventures, natural wonders, and breathtaking views. Start at the increasingly popular Mount Vesuvius, a history-steeped volcano in Naples. Next, go to Archaeological Park Of Pompeii.

After visiting Mount Vesuvius and Archaeological Park Of Pompeii, have a stroll along Naples's streets and take in the local charm. Continue your sightseeing by heading to Lupanare Di Pompei. This UNESCO world heritage-designated archeological site offers a unique experience. Villa Rufolo is another noteworthy attraction worthwhile a visit.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Amalfi. Amalfi offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

Indulge in a memorable dining experience at one of Amalfi's most popular restaurants, and connect with friendly locals for an authentic adventure.

Dine in style at Pasticceria Pansa Amalfi, a top recommendation for dinner tonight. Or, for a change of pace, Grand Hotel Excelsior Amalfi boasts a menu that's sure to impress. Also, be sure to check out Lido Azzurro. Known as a local hotspot, it’s a great choice for tonight in Amalfi.

Unwind after your meal by stepping into Bar Della Valle. This venue is celebrated for its extensive drink selections and cozy vibes.

Raise your glass and celebrate another amazing day of your road trip in Italy!

Dive into day 12 of your remarkable road trip in Italy. Today you will explore Orvieto, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Florence. You’ll stay here for 1 night.

Today’s well-planned self-sightseeing route offers several family-friendly attractions, breathtaking views, and photo-friendly spots. Whether you decide to explore Amalfi on foot, use public transport, or join a guided tour, there are a few attractions you don’t want to miss. Well Of St. Patrick is the first of them. Spend some time admiring this culturally significant monument before continuing your journey. Torre Del Moro Orvieto is your next stop. This worthwhile monument is one of the best-rated sights in Amalfi.

Consider grabbing some lunch or a light snack to keep your energy going. Beyond the above-mentioned attractions, today is also the perfect time to visit Pozzo Della Cava. This photogenic cave is a sight to behold.

At the end of the day, you will drive to Florence, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As dinnertime approaches, it's time to head out for a bite to eat in Florence. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Treat yourself to a wonderful meal at Tijuana, a top-rated dining spot in Florence. If you're in the mood for something new, try Djària - American Bar, another premier location with a delectable menu. You might also want to book a table at The Florence Irish Pub. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Florence.

Take some time to reflect on your day and savor another beautiful night in Italy.