4-Day Italy Self-Drive Road Trip With Itinerary from Brindisi to Alberobello

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Ostuni white town skyline at sunset, Brindisi, Apulia southern Italy. Europe.
Ostuni white town skyline at sunset, Brindisi, Apulia southern Italy. Europe.
A sidewalk cafe with covered patio at the seaside promenade and boardwalk in the city of Brindisi, Italy, in the Puglia region.
Alfonsino castle, located at the entrance to the port of the Italian town of Brindisi, is an interesting example of defensive architecture.
Empty streets and closed shops and cafes on a summer morning on the main street, Corso Umberto, through the town center of the coastal city of Brindisi, Italy.
Photo of Brindisi harbour.
Morning as tourists begin to explore the Brindisi Duomo Cathedral and Bell tower in the Piazza Duomo in Brindisi, Italy, part of the southern Puglia region.
military monument seen from the harbor of Brindisi
photo of view of Panoramic view of Brindisi. Puglia. Italy.
photo of view of Brindisi, Italy.
photo of view of Barletta, Brindisi, Italy.
photo of view of Seafront. Brindisi. Puglia. Italy.
photo of view of Panoramic view of Ostuni white town, Brindisi, Puglia (Apulia), Italy,
photo of view of Piazza Duomo with Brindisi Cathedral near Archiological museum, Brindisi, Italy.
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Explore the best of Italy on a 4-day road trip! Uncover hidden gems and experience the rich culture firsthand as you journey through Brindisi, Matera, Alberobello, Minori, and Amalfi. This road trip itinerary in Italy seamlessly combines exploration with relaxation.

This perfectly planned road trip itinerary in Italy takes you through some of the best places to see in the country. You will spend 2 nights in Brindisi and 1 night in Alberobello. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Italy. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have got you covered.

Upon arriving in Brindisi, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Italy on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Italy. Amalfi Coast and Sassi Di Matera are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Trulli Di Alberobello Puglia, learn more about the unique Belvedere Di Piazza Giovanni Pascoli, and immerse yourself in the vibrant atmosphere of Amici Dei Musei Brindisi.

As you hit the open road and drive through Brindisi, Matera, Alberobello, Minori, and Amalfi, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Italy. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Italy.

Throughout your road trip in Italy, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Italy.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodation, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Italy fill up quickly, so book your spot early. Select a date and start planning your road trip in Italy today!

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Driver’s age is 30 - 65
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Itinerary summary

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Days
Destination
Attractions
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Day
City & Overnight
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Lungomare Regina Margherita
Sassi di MateraPalazzo LanfranchiBelvedere di Piazza Giovanni PascoliCasa Grotta del CasalnuovoTrulli di Alberobello Puglia
Basilica of Saint TrofimenaAmalfi CoastSaint Andrew's Fountain Amalfi
Cillarese Park

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Day 1

Day 1

  • Brindisi - Arrival day
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  • Lungomare Regina Margherita
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Welcome to Brindisi, the perfect starting point for your road trip in Italy! Pick up your rental car and let the adventure begin. You will spend 1 night immersing yourself in Brindisi's charm before embarking on the next leg of your journey.

Brindisi is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Amici Dei Musei Brindisi, or just taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

As afternoon approaches, head to your chosen hotel in Brindisi. Check-in typically starts around 2 to 4 PM at hotels in Italy. We recommend staying at a hotel in a central location for easy access to the best attractions, restaurants, and bars in the city.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Brindisi, it's often a good idea to reserve a table in advance.

Enjoy a delicious meal at Bracerie Escosazio, a top-rated dining destination in Brindisi. If you're in the mood to try something new, consider Penny, another top spot with a mouthwatering menu. You might also want to secure a reservation at Piadineria. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Brindisi this evening.

Let the evening flow smoothly from dinner to drinks at Peddy Bar. Pasticceria. Gelateria. Happyhour. Prodotti Celiaci. Slot Machines. Scommesse, a top-rated bar in the area. For other recommendations, Eden Cafè provides a perfect setting for rounding out your night with style and great drinks. Likewise, Altair Cafè offers a memorable night with diverse drink options and excellent service.

Raise a toast to the start of your 4-day road trip in Italy!

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Day 2

Day 2

  • Brindisi
  • Alberobello
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Drive 224 km, 3 hours 25 min

  • Sassi di Matera
  • Palazzo Lanfranchi
  • Belvedere di Piazza Giovanni Pascoli
  • Casa Grotta del Casalnuovo
  • Trulli di Alberobello Puglia
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Embark on another extraordinary experience on day 2 of your road trip in Italy. Today, you will make 2 stops and experience some of the highlights of Matera and Alberobello. At the end of the day, you will enjoy the comforts of a top-rated hotel in Alberobello, which will be your home away from home for 1 night.

A blend of fun adventures, romantic experiences, and scenic views await you in Brindisi on today’s itinerary. First up is the well-known archeological site, Sassi Di Matera. Afterward, continue to Palazzo Lanfranchi, a museum every traveler should visit.

As you explore Brindisi’s charming streets, take in the lively atmosphere and get to know the character of the city. Next, make your way to Belvedere Di Piazza Giovanni Pascoli. This worthwhile observation deck is an essential stop. Following that, head to Casa Grotta Del Casalnuovo, another must-visit site that will enhance your experience. Don’t forget to stop by Trulli Di Alberobello Puglia, an interesting historical landmark in the city.

When you’re done exploring for the day, you’ll drive to your hotel in Alberobello. Check in and spend some time relaxing before you head out to tour the town.

After a day of adventure, treat yourself to an exquisite dinner at one of Alberobello's best restaurants.

Make sure to reserve a table at Ristorante "I Primi di Puglia" - Alberobello, an iconic dining spot in Alberobello. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world.

Raise your glass and celebrate another amazing day of your road trip in Italy!

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Day 3

Day 3

  • Alberobello
  • Brindisi
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Drive 700 km, 8 hours 59 min

  • Basilica of Saint Trofimena
  • Amalfi Coast
  • Saint Andrew's Fountain Amalfi
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Dive into day 3 of your remarkable road trip in Italy. Today you will explore Minori and Amalfi, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Brindisi. You’ll stay here for 1 night.

Today's adventure in Alberobello promises more breathtaking discoveries and enriching experiences! Begin at Basilica Of Saint Trofimena. This culturally significant church is a highlight of any visit in the village. Next, head over to Saint Andrew's Fountain Amalfi, one of the village’s most intriguing attractions, known for its picture-perfect features.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Brindisi. Brindisi offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

Indulge in a memorable dining experience at one of Brindisi's most popular restaurants, and connect with friendly locals for an authentic adventure.

Enjoy a delicious meal at Betty - Gelateria Cafe Ristorante Pizzeria a Brindisi, a top-rated dining destination in Brindisi. If you're in the mood to try something new, consider Bento, another top spot with a mouthwatering menu. You might also want to secure a reservation at Cozza Nera. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Brindisi this evening.

Savor another day of unforgettable experiences in Italy!

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Day 4

Day 4

  • Brindisi - Departure day
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  • Cillarese Park
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Day 4 of your road trip in Italy is your departure day. This is your chance to catch a last glimpse of Brindisi before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, we recommend visiting Cillarese Park, a gorgeous park before you head out.

Maximize your last day in Italy and go on a shopping spree in Brindisi’s shopping center. Browse for souvenirs to remind you of your wonderful journey in Italy.

Before you conclude your road trip in Italy, drop by another restaurant for a last chance at a memorable dining experience in Brindisi.

Treat yourself to a delightful dinner at Rendez-Vous Cafè Bistrot, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Pizzeria La Nassa? It's another excellent option with a diverse menu.

You’ll then say farewell to Brindisi. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Italy!

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