6-Day Italy Self-Drive Road Trip With Itinerary from Brindisi to Sorrento and Rome

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Escape the ordinary with this exciting 6-day road trip through Italy. Explore the diverse landscapes, lively cities, and beyond. Pack your bags, hit the road, and prepare for an unforgettable journey!

This perfectly planned road trip itinerary in Italy takes you through some of the best places to see in the country. You will spend 3 nights in Brindisi, 1 night in Sorrento, and 1 night in Rome. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Italy. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have got you covered.

Upon arriving in Brindisi, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Italy on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Italy. Trevi Fountain and Pantheon are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Piazza Navona, learn more about the unique Amalfi Coast, and immerse yourself in the vibrant atmosphere of Spanish Steps.

As you hit the open road and drive through Brindisi, Matera, Alberobello, Positano, Amalfi, Ravello, Sorrento, Pompei, Ottaviano, and Rome, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Italy. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Italy.

Throughout your road trip in Italy, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Italy.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodation, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Italy fill up quickly, so book your spot early. Select a date and start planning your road trip in Italy today!

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Driver’s age is 30 - 65
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Itinerary summary

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Days
Destination
Attractions
Overnight
Day
City & Overnight
Attractions
Swabian Castle of Brindisi
Sassi di MateraCasa Grotta del CasalnuovoTrulli di Alberobello PugliaColonne Romane
Chiesa di Santa Maria AssuntaAmalfi CoastVilla Rufolo
Archaeological Park of PompeiiMount VesuviusPiazza Navona
PantheonTrevi FountainSpanish Steps
Palazzo Granafei Nervegna (Brindisi)

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Day 1

Day 1

  • Brindisi - Arrival day
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  • Swabian Castle of Brindisi
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Your road trip adventure in Italy begins as soon as you reach Brindisi and pick up your car. You’ll stay in Brindisi for 2 nights and explore the best things to see and do, sample the local cuisine, and choose from a curated selection of the best hotels and places to stay in the city.

Brindisi is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Swabian Castle Of Brindisi, or just taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

Find your way to your hotel in Brindisi. We recommend choosing a hotel in a central location for easy exploring. Check-in typically starts between 2 and 4 PM at hotels in Italy. Settle in and make plans for the evening.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Brindisi, it's often a good idea to reserve a table in advance.

Enjoy a delicious meal at Bracerie Escosazio, a top-rated dining destination in Brindisi. If you're in the mood to try something new, consider Penny, another top spot with a mouthwatering menu. You might also want to secure a reservation at Piadineria. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Brindisi this evening.

Explore the vibrant nightlife at Peddy Bar. Pasticceria. Gelateria. Happyhour. Prodotti Celiaci. Slot Machines. Scommesse after your meal, a hub for lively evenings and memorable moments. Or, head to Eden Cafè for a great selection of flavorful drinks and a charming setting.

Raise a toast to the start of your 6-day road trip in Italy!

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Day 2

Day 2

  • Brindisi
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Drive 305 km, 4 hours 25 min

  • Sassi di Matera
  • Casa Grotta del Casalnuovo
  • Trulli di Alberobello Puglia
  • Colonne Romane
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On day 2 of your road trip, you’ll start and end your day in Brindisi, where you'll stay for 1 night more.

Enjoy the perfect balance of relaxation and exploration in Brindisi today. One of the most notable attractions included on the itinerary is Sassi Di Matera. This history-steeped archeological site will help you start your sightseeing on top. Then, take a leisurely stroll to Casa Grotta Del Casalnuovo and learn what makes this UNESCO world heritage-listed cave unique.

Throughout the day, make sure to take breaks to appreciate the surroundings. Next up, visit the popular Trulli Di Alberobello Puglia. After exploring the historical landmark, head to End Of The Via Appia Antica. This up-and-coming monument is a highlight in Brindisi.

When you’re done exploring for the day, you’ll return to Brindisi and your accommodation.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Brindisi. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Make sure to reserve a table at Betty - Gelateria Cafe Ristorante Pizzeria a Brindisi, an iconic dining spot in Brindisi. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Bento, a popular restaurant in Brindisi. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Cozza Nera, a hidden gem nestled in Brindisi. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

After your delicious meal, get a taste of the vibrant nightlife with a visit to Altair Cafè, known for its inviting atmosphere.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in in Italy.

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Day 3

Day 3

  • Brindisi
  • Sorrento
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Drive 475 km, 7 hours 22 min

  • Chiesa di Santa Maria Assunta
  • Amalfi Coast
  • Villa Rufolo
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On day 3 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 3 destinations, Positano, Amalfi, and Ravello. When you’re not sightseeing, take time to relax at your selected hotel in Sorrento, where you’ll be staying for 1 night.

Start by visiting Chiesa Di Santa Maria Assunta, a prime spot to begin your journey. This enchanting church is sure to impress.

While exploring and sightseeing, take time to savor the culture of Brindisi by sampling some local delicacies. When you’re ready for more sightseeing, head to Villa Rufolo. This history-steeped historical landmark is an essential place to visit for anyone looking for the full Brindisi experience.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Sorrento. Sorrento offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Sorrento. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Enjoy a delicious meal at Frankie's Pizza Bar Sorrento Brunch & Vegan, a top-rated dining destination in Sorrento. If you're in the mood to try something new, consider Bougainvillea, another top spot with a mouthwatering menu. You might also want to secure a reservation at Banana Split. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Sorrento this evening.

After enjoying a fulfilling meal, continue your evening at Leone Rosso Café, ideal for those looking to unwind with a drink in a comfortable setting. Alternatively, Hotel Antiche Mura Sorrento offers a welcoming atmosphere for easing into the nightlife.

Get a good night's sleep and look forward to another great day on the road in Italy!

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Day 4

Day 4

  • Sorrento
  • Rome
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Drive 293 km, 4 hours 35 min

  • Archaeological Park of Pompeii
  • Mount Vesuvius
  • Piazza Navona
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Experience an unparalleled adventure on day 4 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 3 vibrant destinations - Pompei, Ottaviano, and Rome. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Rome. You will spend 1 night here for some well-deserved relaxation.

Get ready for a day filled with fun adventures, scenic views, and picturesque spots in the charming town of Sorrento. Your adventure starts at Archaeological Park Of Pompeii, an interesting local hot spot. Another notable attraction to explore is Mount Vesuvius. This underrated volcano is known for its awe-inspiring appeal.

After soaking in the highlights of these sights, take some time to wander Sorrento's streets and immerse yourself in the local atmosphere. When you're ready to continue your sightseeing adventure, head to Piazza Navona. This visually striking public square offers a fascinating experience that many visitors find memorable.

When you’re done exploring for the day, you’ll drive to your hotel in Rome. Check in and spend some time relaxing before you head out to tour the city.

As dinnertime approaches, it's time to head out for a bite to eat in Rome. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Treat yourself to a delightful dinner at La Bottega Roma, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Pasta In Corso? It's another excellent option with a diverse menu. Consider reserving a table at Trattoria Vecchia Roma as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Rome.

To truly maximize your evening out, consider visiting La Botticella Of Poggi Giovanni after dinner. This bar is known for offering some of the best drinks and vibes in the city. Alternatively, head to Almalu Trastevere, another bar with an inviting ambiance. Similarly, Bar Viminale Di Pepi Maurilio also offers a great atmosphere, ensuring a night filled with enjoyment and relaxation.

Say good night to Rome and look forward to another great day of your road trip in Italy!

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Day 5

Day 5

  • Rome
  • Brindisi
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Drive 623 km, 6 hours 40 min

  • Pantheon
  • Trevi Fountain
  • Spanish Steps
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On day 5 of your road trip in Italy, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Rome. In the evening, you’ll end up in Brindisi, where you will stay for 1 night.

Rome is brimming with adventures. Today’s wonderful stops include a monument and a public square. Begin your sightseeing adventure at the wondrous Pantheon and allow yourself time to explore. Just a short distance away you'll find your next stop, Trevi Fountain, an enchanting monument that draws visitors from far and near.

Continue your journey to Spanish Steps, one of the city’s most famous spots that you shouldn’t miss.

At the end of the day, you will drive to Brindisi, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

After a day of adventure, treat yourself to an exquisite dinner at one of Brindisi's best restaurants.

Make sure to reserve a table at Rendez-Vous Cafè Bistrot, an iconic dining spot in Brindisi. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Pizzeria La Nassa, a popular restaurant in Brindisi. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Birreria 64, a hidden gem nestled in Brindisi. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Head back to your accommodation in Brindisi and get some rest in preparation for another magical day of your road trip in Italy!

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Day 6

Day 6

  • Brindisi - Departure day
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  • Palazzo Granafei Nervegna (Brindisi)
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Day 6 of your road trip in Italy is your departure day. This is your chance to catch a last glimpse of Brindisi before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, we recommend visiting Palazzo Granafei Nervegna (brindisi), a photogenic palace before you head out.

On your last day in Italy, take time to indulge in shopping at Brindisi’s popular marketplace. Look for keepsakes or souvenirs to remind you of your trip.

Before you conclude your road trip in Italy, drop by another restaurant for a last chance at a memorable dining experience in Brindisi.

If you're in the mood for something new, try Break24, another premier location with a delectable menu.

You’ll then say farewell to Brindisi. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Italy!

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