7-Day Italy Self-Drive Road Trip With Itinerary from Genoa traveling south to Florence, Rome, and Arezzo

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Photo of Sand beach in Camogli by Genoa, Italy.
Photo of Piazza De Ferrari main square in Genoa Italy.
Photo of Courtyard of Palazzo Reale in Genoa, Italy.
Photo of View of Genoa at sunset from "Spianata Castelletto", Italy.
Photo of Sestri Levante - Paradise Bay of Silence with its boats and its lovely beach. Beautiful coast at Province of Genoa in Liguria, Italy - Europe.
Photo of Genoa, Liguria, Italy downtown city skyline from above at dusk.
Photo of The Aquarium of Genoa is the largest aquarium in Italy. Located in the old harbor area of Genova.
Photo of Genoa port from above at night.
Photo of Palace of St George (Palazzo San Giorgio), Genoa, Italy.
Photo of Genova Brignole Railway Station in the evening.
Photo of View of Bogliasco. Bogliasco is a ancient fishing village in Italy, Genoa, Liguria. Mediterranean Sea, sandy beach and architecture of Bogliasco town.
Photo of Beach with tourists in San Fruttuoso bay with the ancient Abbey (San Fruttuoso di Capodimonte), X-XI century, and Andrea Doria tower. Portofino and Camogli, Genoa province, Liguria, Italy, Europe.
Photo of View of Pieve Ligure and on Sori on the background, italian towns of ligurian riviera, Genoa (Genova) province, Italy.
photo of view of Bogliasco, Genoa, Italy town skyline on the Mediterranean sea at sunset.
Aerial view of the Cattedrale di Santa Maria del Fiore in Florence, Italy, overlooking the city
Photo of Florence Aerial View of Ponte Vecchio Bridge during Beautiful Sunny Day, Italy.
Photo of Woman enjoys beautiful view on famous Duomo cathedral in Florence, standing on empty cathedral square during morning time.
Photo of Summer street cafe on Piazza della Repubblica in Florence, Toscana province, Italy.
Photo of Giotto's Campanile - An aerial dusk view of Giotto's Campanile and the historical Old Town of Florence, as seen from the top of Brunelleschi's Dome of the Florence Cathedral. Florence, Tuscany, Italy.
Photo of Ponte Vecchio, old bridge over Arno River, Florence, Tuscany, Italy.
Photo of The Colossus of the Apennines, majestic stone sculpture by Giambologna located in the park of Villa Demidoff in Florence, Italy.
Photo of Fountain of Neptune in Florence in early morning.
Photo of Sunset view of Florence, Ponte Vecchio, Palazzo Vecchio and Florence Duomo, Italy. Architecture and landmark of Florence. Cityscape of Florence.
Vintage carousel and tourists in Piazza della Repubblica (Republic Square) and the arch in honor of the first king of united Italy on background in Florence, Italy.
Photo of Arches of the Vasari Corridor (Corridoio Vasariano) in Florence, Tuscany, Italy. View of the Lungarno degli Archibusieri.
cheerful senior woman cycling with her electric mountain bike above downtown of Florence with stunning view over the old city, Tuscany, Italy
Facade of Palazzo Pitti palace with Gallery of Modern Art large building on Piazza dei Pitti square in historical centre of Florence city, blue sky white clouds, Tuscany, Italy
photo of view of Florence,Italy.
photo of view of Florence,Italy.
Colosseum, Rome, Italy.
Photo of piazza de spagna in Rome, Italy.
Photo of Fountain di Trevi in Rome, Italy.
Bridge Il Tevere a Ponte Vittorio Emanuele II in Rome, Italy.
Hadrian Mausoleum, Rome, Italy.
 Vatican dome of San Pietro and Sant Angelo Bridge, over Tiber river in Rome, Italy.
panoramic view of Rome and St. Peter's Basilica, Italy.
View of Pantheon in the morning, Rome, Italy.
Rome, Italy. Stunning twilight view of Forum ancient ruins, seen from Capitoline hill with Colosseum in background.
Aerial view of forum romanum and surrounding areas of historical centre of italian capital rome.
Cozy old street in Trastevere in Rome, Italy. Trastevere is rione of Rome, on the west bank of the Tiber in Rome, Lazio, Italy. Architecture and landmark of Rome.
Aerial panorama of St. Peter's Square in Vatican with Rome in the background. Italy.
photo of view of Illuminated Fontana Di Trevi, Trevi Fountain at Dusk, Rome, Italy.
photo of view of Spanish Step, Rome, Italy.
photo of view of Museum Luasanne, Rome, Italy.
photo of view Roma Wall of Lugo, Rome, Italy.
photo of view of Roman Bridge Cordoba, Rome, Italy.
photo of view of Roman ruins in Rome, Forum, Rome, Italy.
photo of view of Roman Bridge of Cordoba, Rome, Italy.
photo of view of The Iconic, the legendary Coliseum of Rome, Italy.
photo of view of Rome, Italy: The Roman Forum, Latin: Forum Romanum, Italian: Foro Romano, Rome, Italy.
photo of view of Trevi Fountain (Fontana di Trevi) in Rome, Italy. Trevi is most famous fountain of Rome. Architecture and landmark of Rome, Postcard of Rome, Italy.
photo of view of Arezzo, Italy.
photo of view of Arezzo cathedral and Medici monument, Italy.
photo of view of landscape with Anghiari italian medieval village city walls on green hill and blue sky in background. Arezzo, Italy.
photo of view of acqua ccheta walls casentino national park autumn colors, Arezzo, Italy.
photo of view of Anghiari, Arezzo, Tuscany, Italy: picturesque old narrow alley with staircase in the medieval village, Arezzo, Italy.
photo of view of Anghiari italian medieval village panoramic view. Arezzo, Italy.
photo of view of Medieval monastery of La Verna, in the Arezzo province, Tuscany, Italy.
photo of view of Arezzo, Tuscany, Italy: night view of the main square Piazza Grande, Arezzo, Italy.
photo of view of Aerial view of Bibbiena town, located in the province of Arezzo,, Italy.
photo of view of Arezzo, Italy,
photo of view of Beautiful landscape view of Arezzo town and suburbs in in eastern Tuscany, Italy.
photo of view of Dramatic sky on the famous Piazza Grande square, Arezzo, Tuscany, Italy.
photo of view of Arezzo, Piazza Grande with Christmas decorations, Arezzo, Italy.
photo of view of Tuscany, Arezzo, Santa Maria delle Grazie church built in 1435., Arezzo, Italy.
photo of view of Arezzo museum , Arezzo, Italy.
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Explore the best of Italy on a 7-day road trip! Uncover hidden gems and experience the rich culture firsthand as you journey through Genoa, Florence, Tivoli, Rome, Arezzo, and Pisa. This road trip itinerary in Italy seamlessly combines exploration with relaxation.

This perfectly planned road trip itinerary in Italy takes you through some of the best places to see in the country. You will spend 2 nights in Genoa, 1 night in Florence, 2 nights in Rome, and 1 night in Arezzo. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Italy. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have got you covered.

Upon arriving in Genoa, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Italy on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Italy. Trevi Fountain and Colosseum are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Pantheon, learn more about the unique Piazza Navona, and immerse yourself in the vibrant atmosphere of St. Peter's Basilica.

As you hit the open road and drive through Genoa, Florence, Tivoli, Rome, Arezzo, and Pisa, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Italy. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Italy.

Throughout your road trip in Italy, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Italy.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodation, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Italy fill up quickly, so book your spot early. Select a date and start planning your road trip in Italy today!

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Driver’s age is 30 - 65
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Itinerary summary

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Days
Destination
Attractions
Overnight
Day
City & Overnight
Attractions
piazza De Ferrari
Via GaribaldiGalata - Museo del mareAquarium of Genoaporto antico
Villa d'EsteSaint Peter's SquareSt Peter's Basilica
Castel Sant'AngeloPiazza NavonaPantheonTrevi FountainPiazza di Spagna
Altare della PatriaRoman ForumColosseumpiazza del PopoloVilla Borghese
Pisa CathedralPiazza del Duomo, PisaCampo santo
Landscape from Righi (Funicolare)

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Day 1

Day 1

  • Genoa - Arrival day
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  • piazza De Ferrari
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Your road trip adventure in Italy begins as soon as you reach Genoa and pick up your car. You’ll stay in Genoa for 1 night and explore the best things to see and do, sample the local cuisine, and choose from a curated selection of the best hotels and places to stay in the city.

Genoa is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Piazza De Ferrari, or just taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

Find your way to your hotel in Genoa. We recommend choosing a hotel in a central location for easy exploring. Check-in typically starts between 2 and 4 PM at hotels in Italy. Settle in and make plans for the evening.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Genoa, it's often a good idea to reserve a table in advance.

Dine in style at 7 Sensi cucina decontaminata, a top recommendation for dinner tonight. Or, for a change of pace, Alla Lunga Ristorante boasts a menu that's sure to impress. Also, be sure to check out Grand Hotel Savoia. Known as a local hotspot, it’s a great choice for tonight in Genoa.

Unwind after your meal by stepping into Scurreria Beer & Bagel. This venue is celebrated for its extensive drink selections and cozy vibes. Alternatively, La Lepre offers a dynamic and energetic atmosphere for a glass or two. Don’t overlook Bar Pisacane Iii, another top-rated bar in the area.

Raise a toast to the start of your 7-day road trip in Italy!

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Day 2

Day 2

  • Genoa
  • Florence
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Drive 264 km, 3 hours 46 min

  • Via Garibaldi
  • Galata - Museo del mare
  • Aquarium of Genoa
  • porto antico
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Dive into day 2 of your remarkable road trip in Italy. Today you will explore Genoa, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Florence. You’ll stay here for 1 night.

Whether you prefer a leisurely exploration or a more fast-paced adventure, this itinerary in Genoa allows for both. Start by heading to Via Garibaldi. This locally appreciated street provides an insightful glimpse into the city's identity. Next, discover Galata Museo Del Mare (complex), a history-steeped maritime museum, promising a delightful encounter.

Continue your sightseeing with a visit to Aquarium Of Genoa, a spectacular aquarium. When you’re done, don’t forget to make a stop at the locally renowned Porto Antico.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Florence. Florence offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

As dinnertime approaches, it's time to head out for a bite to eat in Florence. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Discover the culinary delights of Florence by securing a reservation at Enoteca Pinchiorri. Esteemed for its 3-star Guide Michelin recognition, this restaurant offers a remarkable selection of italian contemporary cuisine. For an alternative dining experience, try Santa Elisabetta, renowned for its delicious creative and mediterranean dishes. This esteemed 2-star Michelin-recipient consistently impresses guests, making it a must-visit spot during your holiday. Craving more culinary excitement? Head to Gucci Osteria da Massimo Bottura, a highly recommended local eatery celebrated for its mouthwatering italian contemporary and international menu. With its 1-star Michelin recognition, it offers an unforgettable dining adventure.

Unwind after your meal by stepping into Manifattura. This venue is celebrated for its extensive drink selections and cozy vibes. Alternatively, Se·sto On Arno Rooftop Bar offers a dynamic and energetic atmosphere for a glass or two. Don’t overlook Il Vinile, another top-rated bar in the area.

Take some time to reflect on your day and savor another beautiful night in Italy.

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Day 3

Day 3

  • Florence
  • Rome
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Drive 325 km, 4 hours 19 min

  • Villa d'Este
  • Saint Peter's Square
  • St Peter's Basilica
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Embark on another extraordinary experience on day 3 of your road trip in Italy. Today, you will make 2 stops and experience some of the highlights of Tivoli and Vatican City. At the end of the day, you will enjoy the comforts of a top-rated hotel in Rome, which will be your home away from home for 2 nights.

Immerse yourself in Florence’s rich culture with today's sightseeing itinerary. Start your journey at Villa D'este. This romantic palace is sure to ignite your curiosity.

In between sights, stop by local stores, picturesque photo spots, and small eateries. When you’re ready for your next attraction, proceed to St. Peter's Basilica, a wondrous major basilica.

At the end of the day, you will drive to Rome, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As you explore more of Rome, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Experience a harmony of flavors at La Pergola in Rome by securing a reservation in advance. Known for its 3-star Michelin status, La Pergola offers a delightful variety of dishes highlighting its delicious mediterranean and contemporary menu. If you're seeking an alternative culinary experience, be sure to explore Il Pagliaccio, a highly recommended restaurant known for its enticing creative and innovative cuisine. This popular 2-star Michelin-awarded venue consistently exceeds expectations, ensuring a memorable holiday experience. Ready for another culinary adventure? Indulge your senses at Enoteca La Torre, a highly acclaimed restaurant celebrated for its exceptional mediterranean and creative menu.

Following your dinner, dive into the local bar culture at La Botticella Of Poggi Giovanni. Enjoy this evening's relaxed ambiance with delightful drinks. Alternatively, go to Almalu Trastevere, the perfect place for those looking to experience the best of the nightlife. Similarly, Bar Viminale Di Pepi Maurilio provides excellent drinks and a great atmosphere, ensuring a memorable night out.

Celebrate another amazing day of your road trip adventure in Italy!

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Day 4

Day 4

  • Rome
  • More

Drive 9 km, 1 hour 3 min

  • Castel Sant'Angelo
  • Piazza Navona
  • Pantheon
  • Trevi Fountain
  • Piazza di Spagna
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Day 4 offers a multitude of experiences. You will stay in Rome for 1 night more, offering you enough time to explore at a relaxed pace.

Immerse yourself in Rome’s rich culture with today's sightseeing itinerary. Start your journey at Castel Sant'angelo. This culturally significant castle is sure to ignite your curiosity. Next, dive into the enchanting features of Piazza Navona, a must-visit public square in the city.

In between sights, stop by local stores, picturesque photo spots, and small eateries. When you’re ready for your next attraction, proceed to Pantheon, a timeless monument. For a change of scene, check out Trevi Fountain, known for its romantic features. We also recommend visiting Piazza Di Spagna. This public square is a must for anyone looking to experience the city to the fullest.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Rome. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Have a fantastic dining experience at RomAntica, a highly recommended choice for tonight's dinner. If you're looking to mix things up, Coso Ristorante offers an enticing alternative with its varied menu. Additionally, DEROMA - Farine Romane is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Rome.

After enjoying a delightful dinner, why not delve into the vibrant local bar scene? You might want to spend the evening at Sant' Eustachio Caffè, a well-loved spot among locals and tourists. Or, head to Yellowsquare Rome. This bar boasts a welcoming environment that is perfect for winding down. You could also continue your night at Caffè Portofino, another top-rated place in the area.

Raise your glass and celebrate another amazing day of your road trip in Italy!

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Day 5

Day 5

  • Rome
  • Arezzo
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Drive 226 km, 3 hours 22 min

  • Altare della Patria
  • Roman Forum
  • Colosseum
  • piazza del Popolo
  • Villa Borghese
  • More

Experience an unparalleled adventure on day 5 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 1 vibrant destinations - Rome. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Arezzo. You will spend 1 night here for some well-deserved relaxation.

A blend of family-friendly attractions, breathtaking views, and picturesque spots await you in Rome on today’s itinerary. First up is the notable monument, Altare Della Patria. Afterward, continue to Roman Forum, an archeological site every traveler should visit.

As you explore Rome’s charming streets, take in the lively atmosphere and get to know the character of the city. Next, make your way to Colosseum. This globally renowned archeological site is an essential stop. Following that, head to Piazza Del Popolo, another must-visit site that will enhance your experience. Don’t forget to stop by Villa Borghese, an impressive park in the city.

When you’re done exploring for the day, you’ll drive to your hotel in Arezzo. Check in and spend some time relaxing before you head out to tour the city.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Arezzo. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Set out on a gastronomic journey in Arezzo by reserving a table at Octavin. Renowned for its 1-star Michelin recognition, this restaurant presents an outstanding menu of creative cuisine. Looking for something different? La Clandestina offers a tantalizing alternative with its diverse menu. With its reputation for pleasing customers, it’s a fantastic choice for tonight in Arezzo.

Let the evening flow smoothly from dinner to drinks at Liquid Bar, a top-rated bar in the area.

Relax and recharge in preparation for another adventurous day in Italy!

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Day 6

Day 6

  • Arezzo
  • Genoa
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Drive 322 km, 3 hours 56 min

  • Pisa Cathedral
  • Piazza del Duomo, Pisa
  • Campo santo
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On day 6 of your road trip in Italy, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Pisa. In the evening, you’ll end up in Genoa, where you will stay for 1 night.

Start by visiting Pisa Cathedral, a prime spot to begin your journey. This UNESCO world heritage-listed church is sure to impress. Next on your list is Piazza Del Duomo, Pisa, another must-visit landmark and iconic public square renowned for its symbolic features.

While exploring and sightseeing, take time to savor the culture of Arezzo by sampling some local delicacies. When you’re ready for more sightseeing, head to Campo Santo. This picture-perfect cemetery is an essential place to visit for anyone looking for the full Arezzo experience.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Genoa. Genoa offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Genoa. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Experience a taste of local culinary excellence while in Genoa by securing a table at San Giorgio. An esteemed 1-star Michelin restaurant, it features an exceptional modern and ligurian menu. For an alternative taste experience, visit The Cook, famous for its scrumptious modern dishes. This 1-star Michelin venue consistently impresses guests, making it a standout addition to your holiday plans. Looking for another choice? Discover Il Marin, a local favorite celebrated for its exquisite seafood and contemporary cuisine in Genoa. Located in the heart of the city, this 1-star Michelin restaurant is an ideal pick for seafood and contemporary cuisine lovers seeking top-notch culinary experiences.

Say good night to Genoa and look forward to another great day of your road trip in Italy!

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Day 7

Day 7

  • Genoa - Departure day
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  • Landscape from Righi (Funicolare)
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Day 7 of your road trip in Italy is your departure day. This is your chance to catch a last glimpse of Genoa before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, begin at Landscape From Righi (funicolare). This frequently visited observation deck is a popular place to see in the city.

As your final day in Italy unfolds, enjoy a last-minute shopping spree in Genoa's best shopping area, Porto Antico. Enjoy finding the perfect gift or keepsake to remind you of your wonderful trip to Italy.

Before you conclude your road trip in Italy, drop by another restaurant for a last chance at a memorable dining experience in Genoa.

If you're in the mood to try something new, consider La Cialtroneria, another top spot with a mouthwatering menu.

You’ll then say farewell to Genoa. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Italy!

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