One-Week Italy Self-Drive Road Trip With Itinerary from Venice traveling south to Florence, Lucca, Siena, and Rome

On day 2 of your road trip in Italy, you’ll start and end your day in Venice, but spend the day exploring what’s beyond the city. Since you will return to Venice for 1 night more, there’s no need to rush. Experience Venice and Murano to the fullest today with this curated day itinerary!

Brace yourself for today’s incredible lineup of attractions in Venice, featuring fun adventures, romantic experiences, and breathtaking views. Start at Bridge Of Sighs, a popular monument in the city. Then, head to Doge's Palace and soak in the ambiance of this visually striking palace.

There are many interesting places to see in Venice, and when you are ready for more, go to St Mark's Basilica. This is one of the city’s most notable history-steeped spots of interest. After exploring the church, visit the up-and-coming St Mark's Campanile. Not far away, you'll also find Piazza San Marco. This public square is an UNESCO world heritage-listed highlight in Venice. Before wrapping up your self-guided sightseeing tour, head to Murano, an intriguing handicraft store in the city.

When you’re done exploring for the day, you’ll return to Venice and your accommodation.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Venice. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Treat yourself to a delicious dinner at Generator Venice, an excellent option for tonight's dining. Looking for something different? Nevodi offers a tantalizing alternative with its diverse menu. And don’t miss Ristorante La Piazza. With its reputation for pleasing customers, it’s a fantastic choice for tonight in Venice.

Cap off your culinary experience with a visit to some of the most celebrated bars in the area. For instance, Il Mercante stands out as an excellent choice for a post-dinner cocktail. Alternatively, The Irish Pub Venezia offers an ideal atmosphere to enjoy the pleasures of the night. Ai Stagneri is also a great option that provides a perfect setting for a relaxing evening.

As the sun sets on another day of adventure, rest up and recharge for the next leg of your road trip in Italy.

On day 3 of your road trip in Italy, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Florence. In the evening, you’ll end up in Florence, where you will stay for 1 night.

Venice is brimming with adventures. Today’s wonderful stops include a public square, a church, an art gallery, a historical landmark and much more! Begin your sightseeing adventure at the popular Piazza Della Repubblica and allow yourself time to explore. Just a short distance away you'll find your next stop, Cathedral Of Santa Maria Del Fiore, a culturally significant church that draws visitors from far and near.

Continue your journey to Basilica Of Santa Croce In Florence, one of the city’s most popular spots that you shouldn’t miss. Another great site to visit is the widely recognized Uffizi Gallery. When you're finished at the art gallery, Ponte Vecchio awaits your visit. This historical landmark is a symbolic highlight on today's itinerary. Last up is a public square - the impressive Piazza Della Signoria.

At the end of the day, you will drive to Florence, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Florence. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Have a fantastic dining experience at Ristorante Oliviero 1962, a highly recommended choice for tonight's dinner. If you're looking to mix things up, Di Poneta Novoli offers an enticing alternative with its varied menu. Additionally, Caffe San Firenze is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Florence.

Continue your lively evening at Manifattura, a perfect place for winding down or revving up the night, depending on which mood you’re in. Se·sto On Arno Rooftop Bar is another excellent bar that offers a great selection of drinks to suit any mood. If you prefer to go somewhere else, Il Vinile ensures a night out tailored to your taste.

As the sun sets on another day of adventure, rest up and recharge for the next leg of your road trip in Italy.

Embark on another extraordinary experience on day 4 of your road trip in Italy. Today, you will make 2 stops and experience some of the highlights of Pisa and Lucca. At the end of the day, you will enjoy the comforts of a top-rated hotel in Lucca, which will be your home away from home for 1 night.

Florence is home to plenty of attractions that offer fun adventures, scenic views, and picturesque spots! Start at Campo Santo, a frequently visited cemetery that is worthwhile a visit in the city. Nearby, you’ll find Piazza Del Duomo, Pisa, enchanting visitors with its breathtaking appeal. Continue your exploration at Pisa Cathedral. This church is one of the city’s most frequently visited spots.

Enjoy the freedom of exploring Florence at your own pace and find hidden gems along the way. If you want to see more picture-perfect spots, make sure to visit Leaning Tower Of Pisa. After exploring the monument, head to the locally appreciated Mura Di Lucca. Lastly, wrap up today’s self-guided sightseeing tour with a visit to Piazza Dell'anfiteatro, a place of history-steeped interest in Florence.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Lucca. Lucca offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

As you explore more of Lucca, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Don’t miss out on dining at Gli Orti di Via Elisa, a top-rated dining destination in Lucca. If you're in the mood to try something new, consider Bar Caffè Ristretto, another top spot with a mouthwatering menu. You might also want to secure a reservation at Ristorante Schiaffino. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Lucca this evening.

After enjoying a delightful dinner, why not delve into the vibrant local bar scene? You might want to spend the evening at Lebowski - Cocktail Bar, a well-loved spot among locals and tourists. Or, head to Blend. This bar boasts a welcoming environment that is perfect for winding down. You could also continue your night at Franklin'33, another top-rated place in the area.

Take some time to reflect on your day and savor another beautiful night in Italy.

Experience an unparalleled adventure on day 5 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 1 vibrant destinations - Siena. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Siena. You will spend 1 night here for some well-deserved relaxation.

Whether you prefer a leisurely exploration or a more fast-paced adventure, this itinerary in Lucca allows for both. Start by heading to Porta Camollia, Siena. This worthwhile monument provides an insightful glimpse into the city's identity. Next, discover Basilica Of San Domenico, an awe-inspiring church, promising a delightful encounter.

Continue your sightseeing with a visit to Siena Cathedral, a notable church. When you’re done, don’t forget to make a stop at the underrated Pubblico Palace. Not far away from the palace, you will find the picture-perfect Tower Of Mangia, perfect for a quick visit. Round off your day at Piazza Del Campo, another gem in Lucca with respected features to discover.

When you’re done exploring for the day, you’ll drive to your hotel in Siena. Check in and spend some time relaxing before you head out to tour the city.

As dinnertime approaches, it's time to head out for a bite to eat in Siena. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Enjoy a lovely dining experience at Enoteca I Terzi, a popular restaurant in Siena. This acclaimed establishment has earned the admiration of countless food lovers in the city. Alternatively, experience a taste of Siena at Ristorante Tar-Tufo, another great place to eat. With a menu designed to impress, it promises a journey of flavors that will leave you captivated. A third option to check out is the top-rated Antica Trattoria Papei. It’s yet another ideal choice to enhance your time in Siena tonight.

If you’re not ready to end the night just yet, Meet Life Cafè offers a perfect venue to relax and savor a drink. Similarly, Maudit Pub is well-suited for those looking to unwind in a social setting. Bar Impero Siena is another excellent spot to enjoy a nightcap after a delightful meal.

Say good night to Siena and look forward to another great day of your road trip in Italy!

On day 6 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 1 destination, Rome. When you’re not sightseeing, take time to relax at your selected hotel in Rome, where you’ll be staying for 1 night.

Get ready for an exciting day in Siena. Today’s sightseeing agenda includes an archeological site, a monument, and a public square. Begin your adventure at Colosseum. This is a world-famous archeological site you should not miss. Another must-see is Roman Forum, a world-famous archeological site in Siena.

When you’re ready for the next sight, head to Trevi Fountain. From there, take a leisurely stroll to Pantheon, another of the city’s wondrous attractions. We recommend continuing your self-guided tour at Piazza Navona, a history-steeped place of interest in the city.

At the end of the day, you will drive to Rome, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

After a day of adventure, treat yourself to an exquisite dinner at one of Rome's best restaurants.

Enjoy a delicious meal at La Bottega Roma, a top-rated dining destination in Rome. If you're in the mood to try something new, consider Pasta In Corso, another top spot with a mouthwatering menu. You might also want to secure a reservation at Trattoria Vecchia Roma. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Rome this evening.

After enjoying a fulfilling meal, continue your evening at La Botticella Of Poggi Giovanni, ideal for those looking to unwind with a drink in a comfortable setting. Alternatively, Almalu Trastevere offers a welcoming atmosphere for easing into the nightlife. Similarly, Bar Viminale Di Pepi Maurilio provides an excellent environment for a relaxed and enjoyable evening.

Relax and reminisce about your day in Italy and look forward to more memorable moments to come!