11-Day Italy Self-Drive Road Trip With Itinerary from Genoa traveling east to Florence, Siena, and Rome

On day 2 of your road trip, you’ll start and end your day in Genoa, but spend part of the day exploring places of interest outside the immediate city. On today's itinerary, you'll find attractions in Genoa and Boccadasse. You still have 1 night left in Genoa.

Today’s itinerary in Genoa covers several incredible sights, including a lighthouse, a maritime museum, a street, a public square, a church, a beach and much more! Start your adventure at Lighthouse Of Genoa. This beloved lighthouse is a place that is appreciated by travelers and locals alike. Next, immerse yourself in the standout wonders of Galata Museo Del Mare (complex), a must-see maritime museum in the city.

Consider stopping for a small bite to eat or a drink at a local eatery to keep your energy going. When you’re ready, continue your discovery with a visit to Via Garibaldi. This increasingly popular street offers an enriching experience. For a change of pace, head to Porto Antico, where you can take in romantic features. Conclude your self-guided sightseeing tour with a visit to Church Of St. Anthony Of Boccadasse and Spiaggia Pubblica Di Priaruggia. These sights offer a fulfilling end to a perfect day.

When you’re done exploring for the day, you’ll return to Genoa and your accommodation.

As dinnertime approaches, it's time to head out for a bite to eat in Genoa. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Enjoy a delicious meal at Zeffirino, a top-rated dining destination in Genoa. If you're in the mood to try something new, consider Trattoria Vegia Zena, another top spot with a mouthwatering menu. You might also want to secure a reservation at Trattoria delle Grazie. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Genoa this evening.

Head back to your accommodation in Genoa and get some rest in preparation for another magical day of your road trip in Italy!

Embark on another extraordinary experience on day 3 of your road trip in Italy. Today, you will make 1 stop and experience some of the highlights of Florence. At the end of the day, you will enjoy the comforts of a top-rated hotel in Florence, which will be your home away from home for 2 nights.

Whether you prefer a leisurely exploration or a more fast-paced adventure, this itinerary in Genoa allows for both. Start by heading to Galleria Dell'accademia. This interesting art gallery provides an insightful glimpse into the city's identity. Next, discover Riccardi Medici Palace, a respected palace, promising a delightful encounter.

Continue your sightseeing with a visit to Cathedral Of Santa Maria Del Fiore, an astonishing church. When you’re done, don’t forget to make a stop at the locally appreciated Strozzi Palace Mantua.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Florence. Florence offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

Indulge in a memorable dining experience at one of Florence's most popular restaurants, and connect with friendly locals for an authentic adventure.

Have a fantastic dining experience at Ristorante Oliviero 1962, a highly recommended choice for tonight's dinner. If you're looking to mix things up, Di Poneta Novoli offers an enticing alternative with its varied menu. Additionally, Caffe San Firenze is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Florence.

Cap off your dinner by heading to Manifattura, ideal for a leisurely evening with a drink in hand. Se·sto On Arno Rooftop Bar is another bar that offers an enjoyable setting. Similarly, Il Vinile is also a popular place to go on a night out, perfect for relaxing and socializing.

Take some time to reflect on your day and savor another beautiful night in Italy.

On day 4 of your road trip, you will have an entire day to explore Florence. You’ll stay in Florence for 1 night and discover all the best things to see and do in the area.

Savor the day by visiting some of the best places to see in Florence, including a historical landmark, an art gallery, a palace, a public square, a church, an observation deck and much more! Start your adventure at Ponte Vecchio. This world-famous historical landmark is a must-visit for travelers looking for a unique holiday experience. Make your way to Uffizi Gallery located in Florence for another exciting encounter.

Next, immerse yourself in the setting of Palazzo Vecchio. Its visually striking features will captivate you. After the palace, continue your tour of the city with a visit to Piazza Della Signoria. Visitors usually appreciate the remarkable features of this public square. Next up is Basilica Of Santa Croce In Florence, a highly recommended church. For a change of pace, head to Piazzale Michelangelo. As one of the most extraordinary attractions in Florence, this observation deck is the perfect place to end your self-guided sightseeing tour.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Florence. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Have a fantastic dining experience at Ditta Artigianale, a highly recommended choice for tonight's dinner. If you're looking to mix things up, Trattoria Da Burde offers an enticing alternative with its varied menu. Additionally, Casa Toscana is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Florence.

Unwind after your meal by stepping into Bar 50 Rosso. This venue is celebrated for its extensive drink selections and cozy vibes. Alternatively, Bitter Bar offers a dynamic and energetic atmosphere for a glass or two. Don’t overlook Archea Brewery, another top-rated bar in the area.

Raise your glass and celebrate another amazing day of your road trip in Italy!

On day 5 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 1 destination, Siena. When you’re not sightseeing, take time to relax at your selected hotel in Siena, where you’ll be staying for 2 nights.

Discover a day packed with family-friendly attractions, romantic experiences, and scenic views in Florence. Begin your sightseeing with Siena Cathedral. This interesting church is one of the top attractions in the city. Proceed to Battistero Di San Giovanni Battista, another must-visit attraction.

As you wander through the inviting streets of Florence, soak in the lively ambiance and take the opportunity to snap some photos. Next, head to Pubblico Palace. This worthwhile palace is a traveler-favorite. Not far away, you’ll find Piazza Del Campo, another key site on your sightseeing itinerary. Tower Of Mangia is yet another highly recommended place to visit nearby, offering plenty to discover for curious travelers.

At the end of the day, you will drive to Siena, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Siena. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Make sure to reserve a table at Enoteca I Terzi, an iconic dining spot in Siena. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Ristorante Tar-Tufo, a popular restaurant in Siena. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Antica Trattoria Papei, a hidden gem nestled in Siena. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Cap off your culinary experience with a visit to some of the most celebrated bars in the area. For instance, Meet Life Cafè stands out as an excellent choice for a post-dinner cocktail. Alternatively, Maudit Pub offers an ideal atmosphere to enjoy the pleasures of the night. Bar Impero Siena is also a great option that provides a perfect setting for a relaxing evening.

Raise your glass to another unforgettable day in Italy!

On day 6 of your road trip, you’ll start and end your day in Siena, where you'll stay for 1 night more.

Get ready to discover some of the most iconic wonders in Siena, including a monument, a museum, a public square, a castle, a church and much more! Start your day at Porta San Giovanni. This culturally significant monument is an intriguing place to see in Siena. Then, wander over to Sangimignano1300. If photogenic sites excite you, this museum will be right up your alley. Nearby, you’ll also find Palazzo Comunale, Pinacoteca, Torre Grossa. This historic museum is a favorite among visitors.

Siena offers plenty to explore, ensuring every moment of your visit is filled with excitement and discovery. If you're up for more, Piazza Del Duomo is a beloved spot in the village that will captivate you with its unique charm. When you’re done at the public square, don’t forget to check out the history-steeped Rocca Di Montestaffoli. Take a moment to appreciate the fascinating details of this beloved castle. Wrap up your self-guided tour of Siena's top attractions with a visit to Chiesa Di Sant'agostino.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Siena.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Siena. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Make sure to reserve a table at Osteria Quattro Venti, an iconic dining spot in Siena. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Fischi per Fiaschi, a popular restaurant in Siena. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Osteria da Divo, a hidden gem nestled in Siena. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

To truly maximize your evening out, consider visiting Charlie Mixology Bar Di Aldinucci Riccardo after dinner. This bar is known for offering some of the best drinks and vibes in the city. Alternatively, head to Bar Pinacoteca, another bar with an inviting ambiance. Similarly, San Paolo Pub also offers a great atmosphere, ensuring a night filled with enjoyment and relaxation.

As the sun sets on another day of adventure, rest up and recharge for the next leg of your road trip in Italy.

On day 7 of your road trip in Italy, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Rome. In the evening, you’ll end up in Rome, where you will stay for 3 nights.

Enjoy the perfect balance of relaxation and exploration in Siena today. One of the most timeless attractions included on the itinerary is Colosseum. This historic archeological site will help you start your sightseeing on top. Then, take a leisurely stroll to Roman Forum and learn what makes this picture-perfect archeological site unique.

Throughout the day, make sure to take breaks to appreciate the surroundings. Next up, visit the timeless Trevi Fountain. After exploring the monument, head to Pantheon. This timeless monument is a highlight in Siena. As your day continues, stop by Capitoline Hill, known for its visually striking features.

When you’re done exploring for the day, you’ll drive to your hotel in Rome. Check in and spend some time relaxing before you head out to tour the city.

After a day of adventure, treat yourself to an exquisite dinner at one of Rome's best restaurants.

Treat yourself to a delicious dinner at La Bottega Roma, an excellent option for tonight's dining. Looking for something different? Pasta In Corso offers a tantalizing alternative with its diverse menu. And don’t miss Trattoria Vecchia Roma. With its reputation for pleasing customers, it’s a fantastic choice for tonight in Rome.

To truly maximize your evening out, consider visiting La Botticella Of Poggi Giovanni after dinner. This bar is known for offering some of the best drinks and vibes in the city. Alternatively, head to Almalu Trastevere, another bar with an inviting ambiance. Similarly, Bar Viminale Di Pepi Maurilio also offers a great atmosphere, ensuring a night filled with enjoyment and relaxation.

Celebrate another amazing day of your road trip adventure in Italy!

On day 8 of your road trip in Italy, you’ll start and end your day in Rome, but spend the day exploring what’s beyond the city. Since you will return to Rome for 2 nights more, there’s no need to rush. Experience Vatican City and Rome to the fullest today with this curated day itinerary!

A visit to Trastevere in Vatican City is a must on the agenda today. This neighborhood is full of hidden gems and character, perfect for a leisurely stroll. Plus, you’ll be close to some of the city’s most famous sights.

Start by visiting Vatican Museums, a prime spot to begin your journey.

We also recommend visiting Campo De' Fiori, a spectacular public square. Nearby, you'll also find Piazza Navona, ready to add charm to your journey.

When you’re done exploring for the day, you’ll return to Rome and your accommodation.

As you explore more of Rome, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Enjoy a lovely meal at RomAntica, a top-rated place to have dinner tonight. Alternatively, if your taste buds call for something different, Coso Ristorante is another top choice with a popular menu. You could also check for a table at DEROMA - Farine Romane. As an establishment that gains consistently high praises from customers, it’s an ideal choice in Rome tonight.

Continue your evening by exploring the vibrant nightlife scene at Sant' Eustachio Caffè, a prime destination for a thrilling night out. Also, don’t forget to check out Yellowsquare Rome, a bar that offers unique local touches. Likewise, Caffè Portofino provides an excellent alternative for a fun evening.

Raise your glass and celebrate another amazing day of your road trip in Italy!

At the end of the day, you'll drive back to Rome, where you'll stay for 1 night more.

Immerse yourself in Rome’s rich culture with today's sightseeing itinerary. Start your journey at Villa Borghese. This mesmerizing park is sure to ignite your curiosity. Next, dive into the enchanting features of Passeggiata Del Pincio, a must-visit park in the city.

In between sights, stop by local stores, picturesque photo spots, and small eateries. When you’re ready for your next attraction, proceed to Spanish Steps, an astonishing public square. For a change of scene, check out Piazza Di Spagna, known for its romantic features. We also recommend visiting Basilica Di Santa Maria Maggiore. This church is a must for anyone looking to experience the city to the fullest. Lastly, end your day with a visit to Frascati Cathedral, yet another increasingly popular attraction in Rome.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Rome.

After a day of adventure, treat yourself to an exquisite dinner at one of Rome's best restaurants.

Have a fantastic dining experience at Hotel de Russie, a highly recommended choice for tonight's dinner. If you're looking to mix things up, La Taverna Italiana offers an enticing alternative with its varied menu. Additionally, The Parrot Bar is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Rome.

Round off your dining experience by visiting The Apartment Bar Roma, a prime location for a drink. Alternatively, explore the distinctive characteristics of Hotel Hassler Roma, a bar catering to every mood and preference.

Relax and reminisce about your day in Italy and look forward to more memorable moments to come!

Dive into day 10 of your remarkable road trip in Italy. Today you will explore Orvieto, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Genoa. You’ll stay here for 1 night.

Start by visiting Well Of St. Patrick, a prime spot to begin your journey. This culturally significant monument is sure to impress. Next on your list is Orvieto Cathedral, another must-visit landmark and notable church renowned for its history-steeped features.

While exploring and sightseeing, take time to savor the culture of Rome by sampling some local delicacies. When you’re ready for more sightseeing, head to Orvieto Underground. This respected cave system is an essential place to visit for anyone looking for the full Rome experience. We also recommend visiting Torre Del Moro Orvieto, a frequently visited monument. Nearby, you'll also find Pozzo Della Cava, ready to add charm to your journey.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Genoa. Genoa offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

As you explore more of Genoa, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Enjoy a delicious meal at Osteria Sant'Ilario, a top-rated dining destination in Genoa. If you're in the mood to try something new, consider La Cialtroneria, another top spot with a mouthwatering menu. You might also want to secure a reservation at Manhattan Bar. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Genoa this evening.

Savor another day of unforgettable experiences in Italy!