12-Day Italy Self-Drive Road Trip With Itinerary from Verona to Venice, Florence, Siena, and Rome
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Experience the freedom of the open road in Italy as you embark on an unforgettable 12-day road trip! This experience caters to every traveler, featuring destinations like Verona, Venice, Florence, Pisa, Siena, and Rome.
This perfectly planned road trip itinerary in Italy takes you through some of the best places to see in the country. You will spend 3 nights in Verona, 2 nights in Venice, 3 nights in Florence, 1 night in Siena, and 2 nights in Rome. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!
With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Italy. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have got you covered.
Upon arriving in Verona, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Italy on your own terms.
An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Italy. Trevi Fountain and Colosseum are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Pantheon, learn more about the unique Piazza Navona, and immerse yourself in the vibrant atmosphere of Piazza San Marco.
As you hit the open road and drive through Verona, Venice, Florence, Pisa, Siena, and Rome, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Italy. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Italy.
Throughout your road trip in Italy, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Italy.
This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodation, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.
The best services in Italy fill up quickly, so book your spot early. Select a date and start planning your road trip in Italy today!
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Day 1
- Verona - Arrival day
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- Verona Arena
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Say hello to Verona! Your exciting road trip through Italy is just about to start. Navigating the top places to see in the region is a breeze with a car. The rental vehicle of your choice will be ready for pickup upon your arrival in the city. You will stay in Verona for 2 nights before you continue your adventure!
Verona is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Verona Arena, or just taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.
Find your way to your hotel in Verona. We recommend choosing a hotel in a central location for easy exploring. Check-in typically starts between 2 and 4 PM at hotels in Italy. Settle in and make plans for the evening.
As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Verona, it's often a good idea to reserve a table in advance.
Don’t miss out on dining at La Griglia, a top-rated dining destination in Verona. If you're in the mood to try something new, consider Vecio Macello, another top spot with a mouthwatering menu. You might also want to secure a reservation at Via Fama Cafè | Verona. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Verona this evening.
After your delicious meal, get a taste of the vibrant nightlife with a visit to Archivio, known for its inviting atmosphere. La Segreteria Café is another great option if you’re looking for a place to get the night started. Similarly, Grande Giove Cocktail Bar provides a great setting to enjoy the night away.
Raise a toast to the start of your 12-day road trip in Italy!
Day 2
- Verona
- More
Drive 7 km, 1 hour 26 min
- Basilica di San Zeno Maggiore
- Castelvecchio Museum
- piazza delle Erbe
- piazza dei Signori
- Castel San Pietro
- Giusti Garden
- More
Day 2 offers a multitude of experiences. You will stay in Verona for 1 night more, offering you enough time to explore at a relaxed pace.
Whether you prefer a leisurely exploration or a more fast-paced adventure, this itinerary in Verona allows for both. Start by heading to Basilica Di San Zeno Maggiore. This often recommended church provides an insightful glimpse into the city's identity. Next, discover Castelvecchio Museum, an awe-inspiring museum, promising a delightful encounter.
Continue your sightseeing with a visit to Piazza Delle Erbe, a captivating public square. When you’re done, don’t forget to make a stop at the up-and-coming Piazza Dei Signori. Not far away from the public square, you will find the romantic Giusti Garden, perfect for a quick visit. Round off your day at Castel San Pietro, another gem in Verona with instagrammable features to discover.
Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.
As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Verona. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.
Treat yourself to a wonderful meal at Trattoria I Masenini, a top-rated dining spot in Verona. If you're in the mood for something new, try Osteria da Ugo, another premier location with a delectable menu. You might also want to book a table at Locanda 4 Cuochi. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Verona.
Unwind after your meal by stepping into Duchi Café. This venue is celebrated for its extensive drink selections and cozy vibes. Alternatively, Cambridge Bar offers a dynamic and energetic atmosphere for a glass or two. Don’t overlook Rubicone Caffe, another top-rated bar in the area.
Take some time to reflect on your day and savor another beautiful night in Italy.
Day 3
- Verona
- Venice
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Drive 117 km, 1 hour 55 min
- Grand Canal
- Rialto Bridge
- Bridge of Sighs
- Doge's Palace
- St Mark's Basilica
- Piazza San Marco
- More
Dive into day 3 of your remarkable road trip in Italy. Today you will explore Venice, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Venice. You’ll stay here for 2 nights.
Enjoy the perfect balance of relaxation and exploration in Verona today. One of the most often recommended attractions included on the itinerary is Grand Canal. This visually striking street will help you start your sightseeing on top. Then, take a leisurely stroll to Rialto Bridge and learn what makes this symbolic historical landmark unique.
Throughout the day, make sure to take breaks to appreciate the surroundings. Next up, visit the notable Bridge Of Sighs. After exploring the monument, head to Doge's Palace. This locally renowned palace is a highlight in Verona. As your day continues, stop by St Mark's Basilica, known for its history-steeped features. Lastly, don’t forget to check out the iconic Piazza San Marco. Enjoy exploring this incredible public square at your own pace.
After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Venice. Venice offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.
After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Venice. Enjoy a satisfying meal that will recharge you for tonight's adventures.
Treat yourself to a delicious dinner at Bauer Hotel, an excellent option for tonight's dining. Looking for something different? L'Osteria Le Guglie offers a tantalizing alternative with its diverse menu. And don’t miss Corner Pub. With its reputation for pleasing customers, it’s a fantastic choice for tonight in Venice.
Keep the excitement of the evening going by visiting a bar or two. Al Parlamento is an excellent place to start. You could also check out The Caffe Rosso, offering a different kind of charm. A last recommendation for the day is Adagio. This bar promises an enjoyable experience with tasty drinks and a vibrant setting.
Raise your glass to another unforgettable day in Italy!
Day 4
- Venice
- More
Drive 4 km, 59 min
- Punta della Dogana - Pinault Collection
- Santa Maria della Salute
- Peggy Guggenheim Collection
- Teatro La Fenice
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On day 4 of your road trip, you will have an entire day to explore Venice. You’ll stay in Venice for 1 night and discover all the best things to see and do in the area.
A blend of fun adventures, romantic experiences, and breathtaking views await you in Venice on today’s itinerary. First up is the curiosity-inducing museum, Punta Della Dogana - Pinault Collection. Afterward, continue to Santa Maria Della Salute, a church every traveler should visit.
As you explore Venice’s charming streets, take in the lively atmosphere and get to know the character of the city. Next, make your way to Peggy Guggenheim Collection. This interesting art gallery is an essential stop. Following that, head to Teatro La Fenice, another must-visit site that will enhance your experience.
Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.
Indulge in a memorable dining experience at one of Venice's most popular restaurants, and connect with friendly locals for an authentic adventure.
Treat yourself to a delicious dinner at Generator Venice, an excellent option for tonight's dining. Looking for something different? Nevodi offers a tantalizing alternative with its diverse menu. And don’t miss Ristorante La Piazza. With its reputation for pleasing customers, it’s a fantastic choice for tonight in Venice.
Continue your evening by exploring the vibrant nightlife scene at Il Mercante, a prime destination for a thrilling night out. Also, don’t forget to check out The Irish Pub Venezia, a bar that offers unique local touches. Likewise, Ai Stagneri provides an excellent alternative for a fun evening.
Relax and recharge in preparation for another adventurous day in Italy!
Day 5
- Venice
- Florence
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Drive 260 km, 3 hours 12 min
- Bargello National Museum
- Fountain of Neptune
- Palazzo Vecchio
- Uffizi Gallery
- Ponte Vecchio
- piazza della Signoria
- More
Embark on another extraordinary experience on day 5 of your road trip in Italy. Today, you will make 1 stop and experience some of the highlights of Florence. At the end of the day, you will enjoy the comforts of a top-rated hotel in Florence, which will be your home away from home for 3 nights.
Get ready for an exciting day in Venice. Today’s sightseeing agenda includes a museum, a monument, a palace, an art gallery, a historical landmark, a public square and much more! Begin your adventure at Bargello National Museum. This is an underrated museum you should not miss. Another must-see is Fountain Of Neptune, a beloved monument in Venice.
When you’re ready for the next sight, head to Palazzo Vecchio. From there, take a leisurely stroll to Uffizi Gallery, another of the city’s extraordinary attractions. We recommend continuing your self-guided tour at Ponte Vecchio, a romantic place of interest in the city. If time allows, add Piazza Della Signoria to your itinerary. This astonishing public square offers the perfect finishing touch to your day in Venice.
When you’re done exploring for the day, you’ll drive to your hotel in Florence. Check in and spend some time relaxing before you head out to tour the city.
As you explore more of Florence, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.
Savor the flavors at Ristorante Oliviero 1962, a top pick for dinner tonight. Alternatively, Di Poneta Novoli beckons with its unique menu offerings. Also, consider Caffe San Firenze. With its consistent customer satisfaction, it’s an excellent option for dining in Florence tonight.
After enjoying a delightful dinner, why not delve into the vibrant local bar scene? You might want to spend the evening at Manifattura, a well-loved spot among locals and tourists. Or, head to Se·sto On Arno Rooftop Bar. This bar boasts a welcoming environment that is perfect for winding down. You could also continue your night at Il Vinile, another top-rated place in the area.
As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in in Italy.
Day 6
- Florence
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Drive 9 km, 1 hour 19 min
- David
- Galleria dell'Accademia
- Central Market
- Cathedral of Santa Maria del Fiore
- Basilica of Santa Croce in Florence
- piazzale Michelangelo
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Day 6 of your road trip across Italy promises a magnificent time exploring Florence. You have 2 nights left in Florence. Take the opportunity to experience more of the best attractions and activities in the city.
Start your adventure at David. This interesting statue is a must-visit for travelers looking for a unique holiday experience. Make your way to Galleria Dell'accademia located in Florence for another exciting encounter.
Next, immerse yourself in the setting of Central Market. Its visually striking features will captivate you. After the food market, continue your tour of the city with a visit to Cathedral Of Santa Maria Del Fiore. Visitors usually appreciate the inviting features of this church. Next up is Basilica Of Santa Croce In Florence, a highly recommended church. For a change of pace, head to Piazzale Michelangelo. As one of the most astonishing attractions in Florence, this observation deck is the perfect place to end your self-guided sightseeing tour.
Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.
As dinnertime approaches, it's time to head out for a bite to eat in Florence. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.
Make sure to reserve a table at Ditta Artigianale, an iconic dining spot in Florence. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Trattoria Da Burde, a popular restaurant in Florence. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Casa Toscana, a hidden gem nestled in Florence. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.
After enjoying a fulfilling meal, continue your evening at Bar 50 Rosso, ideal for those looking to unwind with a drink in a comfortable setting. Alternatively, Bitter Bar offers a welcoming atmosphere for easing into the nightlife. Similarly, Archea Brewery provides an excellent environment for a relaxed and enjoyable evening.
Raise your glass to another unforgettable day in Italy!
Day 7
- Florence
- More
Drive 197 km, 3 hours 8 min
- “Tuttomondo” (Keith Haring)
- Leaning Tower of Pisa
- Angelo Caduto
- Pisa Cathedral
- Campo santo
- Piazza del Duomo, Pisa
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Greet day 7 of your road trip in Italy with a smile and start your day with a hearty breakfast. You will return to Florence for your remaining 1 night in the city later today, but first, it’s time for some exploring! On the agenda for this day, you’ll find only the best things to see and do in Pisa.
Today's adventure in Florence promises more breathtaking discoveries and enriching experiences! Begin at “tuttomondo” (keith Haring). This photogenic art installation is a highlight of any visit in the city. Then, enjoy Leaning Tower Of Pisa, another historic attraction that never fails to captivate visitors.
If you’re looking for more, spend time soaking in the atmosphere of Pisa Cathedral. This stunning church is frequented by locals and tourists alike. To complete your memorable day, make sure to visit Campo Santo, an intriguing cemetery, and take a stroll around the area. If you want to extend your self-guided sightseeing tour, go check out Piazza Del Duomo, Pisa before you head back to your hotel.
When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Florence.
After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Florence. Enjoy a satisfying meal that will recharge you for tonight's adventures.
Savor the flavors at Ristorante Buca Mario, a top pick for dinner tonight. Alternatively, Agricola Toscana beckons with its unique menu offerings. Also, consider Eataly Firenze. With its consistent customer satisfaction, it’s an excellent option for dining in Florence tonight.
If you’re not ready to end the night just yet, Gosh* offers a perfect venue to relax and savor a drink. Similarly, Antico Caffè Del Moro - Art Bar Firenze is well-suited for those looking to unwind in a social setting. Quelo Bar is another excellent spot to enjoy a nightcap after a delightful meal.
Get a good night's sleep and look forward to another great day on the road in Italy!
Day 8
- Florence
- Siena
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Drive 77 km, 1 hour 45 min
- Fortezza Medicea
- Basilica of San Domenico
- Siena Cathedral
- Pubblico Palace
- piazza del Campo
- Tower of Mangia
- More
On day 8 of your road trip in Italy, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Siena. In the evening, you’ll end up in Siena, where you will stay for 1 night.
Florence is brimming with adventures. Today’s wonderful stops include a monument, a church, a palace, a public square and much more! Begin your sightseeing adventure at the frequently visited Fortezza Medicea (siena) and allow yourself time to explore. Just a short distance away you'll find your next stop, Basilica Of San Domenico, a stunning church that draws visitors from far and near.
Continue your journey to Siena Cathedral, one of the city’s most interesting spots that you shouldn’t miss. Another great site to visit is the frequently visited Pubblico Palace. When you're finished at the palace, Piazza Del Campo awaits your visit. This public square is an enchanting highlight on today's itinerary. Last up is a monument - the worthwhile Tower Of Mangia.
At the end of the day, you will drive to Siena, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.
Indulge in a memorable dining experience at one of Siena's most popular restaurants, and connect with friendly locals for an authentic adventure.
Treat yourself to a delightful dinner at Enoteca I Terzi, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Ristorante Tar-Tufo? It's another excellent option with a diverse menu. Consider reserving a table at Antica Trattoria Papei as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Siena.
After your meal, keep the night alive at a bar like Meet Life Cafè, known for its lively atmosphere. Maudit Pub is another top recommendation that provides the perfect setting with well-crafted drinks and a welcoming ambiance. Similarly, Bar Impero Siena offers an excellent atmosphere for those looking to amp up the evening.
Savor another day of unforgettable experiences in Italy!
Day 9
- Siena
- Rome
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Drive 242 km, 3 hours 37 min
- Colosseum
- Roman Forum
- Piazza Navona
- Capitoline Museums
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Experience an unparalleled adventure on day 9 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 1 vibrant destinations - Rome. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Rome. You will spend 2 nights here for some well-deserved relaxation.
Brace yourself for today’s incredible lineup of attractions in Siena, featuring family-friendly attractions, scenic views, and picturesque spots. Start at Colosseum, an iconic archeological site in the city. Then, head to Roman Forum and soak in the ambiance of this breathtaking archeological site.
There are many interesting places to see in Siena, and when you are ready for more, go to Piazza Navona. This is one of the city’s most globally renowned enchanting spots of interest. After exploring the public square, visit the interesting Capitoline Museums.
After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Rome. Rome offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.
As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Rome. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.
Enjoy a lovely dining experience at La Bottega Roma, a popular restaurant in Rome. This acclaimed establishment has earned the admiration of countless food lovers in the city. Alternatively, experience a taste of Rome at Pasta In Corso, another great place to eat. With a menu designed to impress, it promises a journey of flavors that will leave you captivated. A third option to check out is the top-rated Trattoria Vecchia Roma. It’s yet another ideal choice to enhance your time in Rome tonight.
To truly maximize your evening out, consider visiting La Botticella Of Poggi Giovanni after dinner. This bar is known for offering some of the best drinks and vibes in the city. Alternatively, head to Almalu Trastevere, another bar with an inviting ambiance. Similarly, Bar Viminale Di Pepi Maurilio also offers a great atmosphere, ensuring a night filled with enjoyment and relaxation.
Relax and reminisce about your day in Italy and look forward to more memorable moments to come!
Day 10
- Rome
- More
Drive 10 km, 1 hour 7 min
- St Peter's Basilica
- The Last Judgment
- Sistine Chapel
- Vatican Museums
- Castel Sant'Angelo
- Trastevere
- More
At the end of the day, you'll drive back to Rome, where you'll stay for 1 night more.
Make sure to visit Trastevere, a popular neighborhood in Vatican City. Spend some time wandering around the area and soak in its distinctive charm. You’ll also discover that several of the city’s must-see attractions are just around the corner.
Enjoy the perfect balance of relaxation and exploration in Rome today. One of the most globally renowned attractions included on the itinerary is St. Peter's Basilica.
Throughout the day, make sure to take breaks to appreciate the surroundings. Next up, visit the top-rated Sistine Chapel. After exploring the chapel, head to Vatican Museums. This wondrous art museum is a highlight in Rome. As your day continues, stop by Castel Sant'angelo, known for its romantic features.
When you’re done exploring for the day, you’ll return to Rome and your accommodation.
As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Rome. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.
Enjoy a lovely meal at RomAntica, a top-rated place to have dinner tonight. Alternatively, if your taste buds call for something different, Coso Ristorante is another top choice with a popular menu. You could also check for a table at DEROMA - Farine Romane. As an establishment that gains consistently high praises from customers, it’s an ideal choice in Rome tonight.
After savoring a delicious meal, step into the vibrant nightlife at Sant' Eustachio Caffè, where the evening is just getting started. In the same way, Yellowsquare Rome offers a unique charm perfect for experiencing the local bar scene in Rome. Caffè Portofino is another top-recommended bar that is sure to get you into the mood for some dancing and celebrating.
Raise your glass to another unforgettable day in Italy!
Day 11
- Rome
- Verona
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Drive 515 km, 5 hours 57 min
- Pantheon
- Trevi Fountain
- Spanish Steps
- Piazza di Spagna
- Basilica di Santa Maria Maggiore
- More
On day 11 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 1 destination, Rome. When you’re not sightseeing, take time to relax at your selected hotel in Verona, where you’ll be staying for 1 night.
Discover a day packed with family-friendly attractions, picturesque spots, and history-rich sites in Rome. Begin your sightseeing with Pantheon. This wondrous monument is one of the top attractions in the city. Proceed to Trevi Fountain, another must-visit attraction.
As you wander through the inviting streets of Rome, soak in the lively ambiance and take the opportunity to snap some photos. Next, head to Spanish Steps. This famous public square is a traveler-favorite. Not far away, you’ll find Piazza Di Spagna, another key site on your sightseeing itinerary. Basilica Di Santa Maria Maggiore is yet another highly recommended place to visit nearby, offering plenty to discover for curious travelers.
When you’re done exploring for the day, you’ll drive to your hotel in Verona. Check in and spend some time relaxing before you head out to tour the city.
After a day of adventure, treat yourself to an exquisite dinner at one of Verona's best restaurants.
Treat yourself to a wonderful meal at Re Teodorico, a top-rated dining spot in Verona. If you're in the mood for something new, try La Piazzetta Osteria Enoteca, another premier location with a delectable menu. You might also want to book a table at Santa Felicita Ristorante. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Verona.
After your delicious meal, get a taste of the vibrant nightlife with a visit to Cappa Café, known for its inviting atmosphere. Vecia Veroneta is another great option if you’re looking for a place to get the night started.
Raise your glass and celebrate another amazing day of your road trip in Italy!
Day 12
- Verona - Departure day
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- Porta Borsari
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Day 12 of your road trip in Italy is your departure day. This is your chance to catch a last glimpse of Verona before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.
If you're up for some more sightseeing, we recommend visiting Porta Borsari, an eye-catching historical landmark before you head out.
On your last day in Italy, take time to indulge in shopping at Verona’s popular marketplace, Piazza delle Erbe. Look for keepsakes or souvenirs to remind you of your trip.
Before you conclude your road trip in Italy, drop by another restaurant for a last chance at a memorable dining experience in Verona.
If you're in the mood to try something new, consider Ristorante Vittorio Emanuele, another top spot with a mouthwatering menu.
You’ll then say farewell to Verona. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Italy!
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