5-Day Italy Self-Drive Road Trip With Itinerary from Genoa to Portofino and Pisa

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Experience the freedom of the open road in Italy as you embark on an unforgettable 5-day road trip! This experience caters to every traveler, featuring destinations like Genoa, Portofino, Corniglia, Pisa, Florence, and Lucca.

This perfectly planned road trip itinerary in Italy takes you through some of the best places to see in the country. You will spend 2 nights in Genoa, 1 night in Portofino, and 1 night in Pisa. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Italy. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have got you covered.

Upon arriving in Genoa, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Italy on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Italy. Ponte Vecchio and Leaning Tower Of Pisa are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Piazza Del Duomo, Pisa, learn more about the unique Uffizi Gallery, and immerse yourself in the vibrant atmosphere of Aquarium Of Genoa.

As you hit the open road and drive through Genoa, Portofino, Corniglia, Pisa, Florence, and Lucca, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Italy. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Italy.

Throughout your road trip in Italy, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Italy.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodation, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Italy fill up quickly, so book your spot early. Select a date and start planning your road trip in Italy today!

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Driver’s age is 30 - 65
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Itinerary summary

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Days
Destination
Attractions
Overnight
Day
City & Overnight
Attractions
Aquarium of Genoa
piazza De FerrariGenoa CathedralDoge's PalaceVia GaribaldiGalata - Museo del mareArea Marina Protetta di Portofino
Cinque Terre National ParkLeaning Tower of PisaPiazza del Duomo, Pisa
Basilica of Santa Croce in FlorenceUffizi GalleryPonte VecchioWalls of Lucca
porto antico

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Day 1

Day 1

  • Genoa - Arrival day
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  • Aquarium of Genoa
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Say hello to Genoa! Your exciting road trip through Italy is just about to start. Navigating the top places to see in the region is a breeze with a car. The rental vehicle of your choice will be ready for pickup upon your arrival in the city. You will stay in Genoa for 1 night before you continue your adventure!

Genoa is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Aquarium Of Genoa, or just taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

Find your way to your hotel in Genoa. We recommend choosing a hotel in a central location for easy exploring. Check-in typically starts between 2 and 4 PM at hotels in Italy. Settle in and make plans for the evening.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Genoa, it's often a good idea to reserve a table in advance.

Enjoy a delicious meal at 7 Sensi cucina decontaminata, a highly-rated dining destination in Genoa. If you're eager to try something different, consider Alla Lunga Ristorante, another top spot with a tantalizing menu. You might also want to secure a reservation at Grand Hotel Savoia. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Genoa this evening.

Keep the excitement of the evening going by visiting a bar or two. Scurreria Beer & Bagel is an excellent place to start. You could also check out La Lepre, offering a different kind of charm. A last recommendation for the day is Bar Pisacane Iii. This bar promises an enjoyable experience with tasty drinks and a vibrant setting.

Raise a toast to the start of your 5-day road trip in Italy!

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Day 2

Day 2

  • Genoa
  • Portofino
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Drive 58 km, 1 hour 51 min

  • piazza De Ferrari
  • Genoa Cathedral
  • Doge's Palace
  • Via Garibaldi
  • Galata - Museo del mare
  • Area Marina Protetta di Portofino
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On day 2 of your road trip in Italy, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Genoa and San Fruttuoso di Camogli. In the evening, you’ll end up in Portofino, where you will stay for 1 night.

Discover a day packed with fun adventures, romantic experiences, and breathtaking views in Genoa. Begin your sightseeing with Piazza De Ferrari. This locally renowned public square is one of the top attractions in the city. Proceed to Genoa Cathedral, another must-visit attraction.

As you wander through the inviting streets of Genoa, soak in the lively ambiance and take the opportunity to snap some photos. Next, head to Doge's Palace. This often recommended museum is a traveler-favorite. Not far away, you’ll find Via Garibaldi, another key site on your sightseeing itinerary. Galata Museo Del Mare (complex) is yet another highly recommended place to visit nearby, offering plenty to discover for curious travelers. Conclude your day at Area Marina Protetta Di Portofino and uncover why it's recognized as one of the city's most worthwhile attractions.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Portofino. Portofino offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Portofino. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Make sure to reserve a table at Trattoria Concordia, an iconic dining spot in Portofino. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Ristorante Da Ö Batti Portofino - Ristorante Da Ö Batti, a popular restaurant in Portofino. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Ristorante Puny, a hidden gem nestled in Portofino. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Raise your glass and celebrate another amazing day of your road trip in Italy!

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Day 3

Day 3

  • Portofino
  • Pisa
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Drive 185 km, 3 hours 33 min

  • Cinque Terre National Park
  • Leaning Tower of Pisa
  • Piazza del Duomo, Pisa
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Dive into day 3 of your remarkable road trip in Italy. Today you will explore Corniglia and Pisa, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Pisa. You’ll stay here for 1 night.

Today’s route brings family-friendly attractions, romantic experiences, and natural wonders. The first attraction of today is Cinque Terre National Park. This popular national park is a serene place to see in Portofino. Continue your discovery at Leaning Tower Of Pisa, a culturally significant monument with stories to tell.

As you stroll around Portofino, take in the distinct atmosphere and learn what makes this village so unique. Maximize your sightseeing with a visit to Piazza Del Duomo, Pisa. This iconic public square offers an UNESCO world heritage-listed encounter with Portofino. Whether you decide to get entrance tickets for all attractions or you prefer admiring from a distance, amazing experiences await on this day in Portofino.

At the end of the day, you will drive to Pisa, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As dinnertime approaches, it's time to head out for a bite to eat in Pisa. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Treat yourself to a wonderful meal at Anima di Grano Pizzeria Napoletana Pisa Italy, a top-rated dining spot in Pisa. If you're in the mood for something new, try il Mercante, another premier location with a delectable menu. You might also want to book a table at La Ghiotteria. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Pisa.

Cap off your culinary experience with a visit to some of the most celebrated bars in the area. For instance, Jeffer Cocktails & Friends stands out as an excellent choice for a post-dinner cocktail. Alternatively, Le Parisien Wine Bar offers an ideal atmosphere to enjoy the pleasures of the night. Las Volta Cocktailbar is also a great option that provides a perfect setting for a relaxing evening.

Take some time to reflect on your day and savor another beautiful night in Italy.

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Day 4

Day 4

  • Pisa
  • Genoa
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Drive 323 km, 4 hours 28 min

  • Basilica of Santa Croce in Florence
  • Uffizi Gallery
  • Ponte Vecchio
  • Walls of Lucca
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On day 4 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 2 destinations, Florence and Lucca. When you’re not sightseeing, take time to relax at your selected hotel in Genoa, where you’ll be staying for 1 night.

Today’s agenda in Pisa includes a church, an art gallery, and a historical landmark. Basilica Of Santa Croce In Florence is must-visit church and a great starting point for the day. Next, continue your journey to Uffizi Gallery, a top-rated art gallery, located just a leisurely stroll away. Next, head to Ponte Vecchio, a visually striking historical landmark, also available for your discovery today.

When you’re done exploring for the day, you’ll drive to your hotel in Genoa. Check in and spend some time relaxing before you head out to tour the city.

As you explore more of Genoa, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Don’t miss out on dining at Zeffirino, a top-rated dining destination in Genoa. If you're in the mood to try something new, consider Trattoria Vegia Zena, another top spot with a mouthwatering menu. You might also want to secure a reservation at Trattoria delle Grazie. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Genoa this evening.

Savor another day of unforgettable experiences in Italy!

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Day 5

Day 5

  • Genoa - Departure day
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  • porto antico
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Day 5 of your road trip in Italy is your departure day. This is your chance to catch a last glimpse of Genoa before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, we recommend visiting Porto Antico, a standout public square before you head out.

As your final day in Italy unfolds, enjoy a last-minute shopping spree in Genoa's best shopping area, Via XX Settembre. Enjoy finding the perfect gift or keepsake to remind you of your wonderful trip to Italy.

Before you conclude your road trip in Italy, drop by another restaurant for a last chance at a memorable dining experience in Genoa.

If you're in the mood to try something new, consider La Cialtroneria, another top spot with a mouthwatering menu.

You’ll then say farewell to Genoa. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Italy!

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