7-Day Greece Self-Drive Road Trip With Itinerary from Thessaloniki to Kavala Prefecture, Xanthi, Serres, and Larissa and surrounding area

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Escape the ordinary with this exciting 7-day road trip through Greece. Explore the diverse landscapes, lively cities, and beyond. Pack your bags, hit the road, and prepare for an unforgettable journey!

This perfectly planned road trip itinerary in Greece takes you through some of the best places to see in the country. You will spend 2 nights in Thessaloniki, 1 night in Kavala Prefecture, 1 night in Xanthi, 1 night in Serres, and 1 night in Larissa. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Greece. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have got you covered.

Upon arriving in Thessaloniki, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Greece on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Greece. White Tower Of Thessaloniki and Aristotelous Square are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable The Umbrellas Sculpture By Zogolopoulos, learn more about the unique Arch Of Galerius And Rotunda, and immerse yourself in the vibrant atmosphere of Agias Sofias Square.

As you hit the open road and drive through Thessaloniki, Kavala Prefecture, Alexandroupoli, Xanthi, Krinides, Lydia, Aggitis, Serres, Vergina, Katerini, Larissa, Makrinitsa, Portaria, and Volos, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Greece. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Greece.

Throughout your road trip in Greece, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Greece.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodation, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Greece fill up quickly, so book your spot early. Select a date and start planning your road trip in Greece today!

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Driver’s age is 30 - 65
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Itinerary summary

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Days
Destination
Attractions
Overnight
Day
City & Overnight
Attractions
Ladadika
Aristotelous SquareAgias Sofias SquareWhite Tower of ThessalonikiThe Umbrellas by Zongolopoulos
Kavala FortFaliro ParkLighthouse of AlexandroupoliThe House of ShadowDimokratias Square
Ancient theatre of PhilippiArchaeological Museum of PhilippiHoly Baptistery of Saint Lydia of PhilippiCave Aggitis River
Liberty SquarePolycentric Museum of Aigai (Aegae) - Main BuildingMuseum of the Royal Tombs at Aigai (Aegae)Katerini Municipal Park
Makrinitsa Central SquareCentaurs' pathSaint Konstantinos ParkΠαραλία Βόλου
Arch of Galerius

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Day 1

Day 1

  • Thessaloniki - Arrival day
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  • Ladadika
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Your road trip adventure in Greece begins as soon as you reach Thessaloniki and pick up your car. You’ll stay in Thessaloniki for 1 night and explore the best things to see and do, sample the local cuisine, and choose from a curated selection of the best hotels and places to stay in the city.

Thessaloniki is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Ladadika, a must-see neighborhood, and taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

Make your way to your chosen hotel. Check-in typically starts between 2 and 4 PM in Thessaloniki. Make yourself at home and enjoy some downtime before heading out again.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Thessaloniki, it's often a good idea to reserve a table in advance.

Have a fantastic dining experience at Kitchen Bar, a highly recommended choice for tonight's dinner. If you're looking to mix things up, The Greek offers an enticing alternative with its varied menu. Additionally, Phanós is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Thessaloniki.

Let the evening flow smoothly from dinner to drinks at Beetle Bar, a top-rated bar in the area. For other recommendations, Vogatsikou 3 provides a perfect setting for rounding out your night with style and great drinks. Likewise, Souel offers a memorable night with diverse drink options and excellent service.

Raise a toast to the start of your 7-day road trip in Greece!

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Day 2

Day 2

  • Thessaloniki
  • Kavala
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Drive 161 km, 2 hours 30 min

  • Aristotelous Square
  • Agias Sofias Square
  • White Tower of Thessaloniki
  • The Umbrellas by Zongolopoulos
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On day 2 of your road trip in Greece, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Thessaloniki. In the evening, you’ll end up in Kavala Prefecture, where you will stay for 1 night.

Enjoy the perfect balance of relaxation and exploration in Thessaloniki today. One of the most interesting attractions included on the itinerary is Aristotelous Square. This romantic public square will help you start your sightseeing on top. Then, take a leisurely stroll to Agias Sofias Square and learn what makes this eye-catching public square unique.

Throughout the day, make sure to take breaks to appreciate the surroundings. Next up, visit the impressive White Tower Of Thessaloniki. After exploring the monument, head to The Umbrellas Sculpture By Zogolopoulos. This well-known art installation is a highlight in Thessaloniki.

At the end of the day, you will drive to Kavala Prefecture, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Kavala Prefecture. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Make sure to reserve a table at Meltemi, an iconic dining spot in Kavala Prefecture. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Tsalapeteinos (Tsalapeteinos Urban Farm), a popular restaurant in Kavala Prefecture. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Marine Cafe Bar Restaurant, a hidden gem nestled in Kavala Prefecture. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Cap off your dinner by heading to Sofita, ideal for a leisurely evening with a drink in hand. Beyond Cafe-bar is another bar that offers an enjoyable setting. Similarly, Brickwall Pub is also a popular place to go on a night out, perfect for relaxing and socializing.

Celebrate another amazing day of your road trip adventure in Greece!

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Day 3

Day 3

  • Kavala
  • Xanthi
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Drive 254 km, 3 hours 23 min

  • Kavala Fort
  • Faliro Park
  • Lighthouse of Alexandroupoli
  • The House of Shadow
  • Dimokratias Square
  • More

Experience an unparalleled adventure on day 3 of your road trip in Greece. This exciting part of your journey invites you to discover the renowned landmarks in 3 vibrant destinations - Kavala Prefecture, Alexandroupoli, and Xanthi. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Xanthi. You will spend 1 night here for some well-deserved relaxation.

Today’s well-planned self-sightseeing route offers several family-friendly attractions, romantic experiences, and scenic views. Whether you decide to explore Kavala Prefecture on foot, use public transport, or join a guided tour, there are a few attractions you don’t want to miss. Kavala Fortress is the first of them. Spend some time admiring this history-steeped castle before continuing your journey. Faliro Park is your next stop. This beloved park is one of the best-rated sights in Kavala Prefecture.

Consider grabbing some lunch or a light snack to keep your energy going. Beyond the above-mentioned attractions, today is also the perfect time to visit Lighthouse Of Alexandroupoli. This romantic lighthouse is a sight to behold. To round off your sightseeing experience, visit The House Of Shadow and Republic Square.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Xanthi. Xanthi offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

After a day of adventure, treat yourself to an exquisite dinner at one of Xanthi's best restaurants.

Enjoy a delicious meal at Fanarakia, a top-rated dining destination in Xanthi. If you're in the mood to try something new, consider KooKooVaya Urban Gastronomy, another top spot with a mouthwatering menu. You might also want to secure a reservation at Amalthia. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Xanthi this evening.

After your meal, keep the night alive at a bar like Βaiser Cafe-bar, known for its lively atmosphere. Mikro Cafe is another top recommendation that provides the perfect setting with well-crafted drinks and a welcoming ambiance. Similarly, Nostos offers an excellent atmosphere for those looking to amp up the evening.

Get a good night's sleep and look forward to another great day on the road in Greece!

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Day 4

Day 4

  • Xanthi
  • Serres Regional Unit
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Drive 194 km, 3 hours 15 min

  • Ancient theatre of Philippi
  • Archaeological Museum of Philippi
  • Holy Baptistery of Saint Lydia of Philippi
  • Cave Aggitis River
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Dive into day 4 of your remarkable road trip in Greece. Today you will explore Krinides, Lydia, and Aggitis, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Serres. You’ll stay here for 1 night.

Xanthi is brimming with adventures. Today’s wonderful stops include an archeological site, a museum, a church, a cave and much more! Begin your sightseeing adventure at the often recommended Ancient Theatre Of Philippi and allow yourself time to explore. Just a short distance away you'll find your next stop, Archaeological Museum Of Philippi, an eye-catching museum that draws visitors from far and near.

Continue your journey to Holy Baptistery Of Saint Lydia Of Philippi, one of the town’s most often recommended spots that you shouldn’t miss. Another great site to visit is the underrated Aggitis River Cave.

When you’re done exploring for the day, you’ll drive to your hotel in Serres. Check in and spend some time relaxing before you head out to tour the city.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Serres. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Enjoy a delicious meal at Oyzadikon To Bakalikon, a highly-rated dining destination in Serres. If you're eager to try something different, consider KENTRIKON Ouzomezedopoleio, another top spot with a tantalizing menu. You might also want to secure a reservation at Sousouráda. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Serres this evening.

Keep the excitement of the evening going by visiting a bar or two. Avissunia Kafe is an excellent place to start. You could also check out Resalto Pub, offering a different kind of charm. A last recommendation for the day is 1800 Cafe Bar. This bar promises an enjoyable experience with tasty drinks and a vibrant setting.

Head back to your accommodation in Serres and get some rest in preparation for another magical day of your road trip in Greece!

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Day 5

Day 5

  • Serres Regional Unit
  • Larissa
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Drive 277 km, 3 hours 49 min

  • Liberty Square
  • Polycentric Museum of Aigai (Aegae) - Main Building
  • Museum of the Royal Tombs at Aigai (Aegae)
  • Katerini Municipal Park
  • More

Embark on another extraordinary experience on day 5 of your road trip in Greece. Today, you will make 3 stops and experience some of the highlights of Serres, Vergina, and Katerini. At the end of the day, you will enjoy the comforts of a top-rated hotel in Larissa, which will be your home away from home for 1 night.

A blend of family-friendly attractions, picturesque spots, and wallet-friendly activities await you in Serres on today’s itinerary. First up is the intriguing public square, Liberty Square. Afterward, continue to Polycentric Museum Of Aigai (aegae) - Main Building, a museum every traveler should visit.

As you explore Serres’s charming streets, take in the lively atmosphere and get to know the character of the city. Next, make your way to Museum Of The Royal Tombs At Aigai (aegae). This underrated museum is an essential stop. Following that, head to Katerini Municipal Park, another must-visit site that will enhance your experience.

At the end of the day, you will drive to Larissa, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As you explore more of Larissa, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Enjoy a lovely meal at Nonna Rossa, a top-rated place to have dinner tonight. Alternatively, if your taste buds call for something different, Vosporos | Restaurant • Bar is another top choice with a popular menu. You could also check for a table at THE ALLEY. As an establishment that gains consistently high praises from customers, it’s an ideal choice in Larissa tonight.

Let the evening flow smoothly from dinner to drinks at Sherlock Easy Bar, a top-rated bar in the area. For other recommendations, Kiou provides a perfect setting for rounding out your night with style and great drinks. Likewise, Wisedog offers a memorable night with diverse drink options and excellent service.

As the sun sets on another day of adventure, rest up and recharge for the next leg of your road trip in Greece.

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Day 6

Day 6

  • Larissa
  • Thessaloniki
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Drive 294 km, 4 hours 15 min

  • Makrinitsa Central Square
  • Centaurs' path
  • Saint Konstantinos Park
  • Παραλία Βόλου
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On day 6 of your exciting self-drive vacation in Greece, you’ll soak in the magnificence of 3 destinations, Makrinitsa, Portaria, and Volos. When you’re not sightseeing, take time to relax at your selected hotel in Thessaloniki, where you’ll be staying for 1 night.

Bring your curiosity for today’s adventure around Larissa. Some of the village’s most loved attractions await! Makrinitsa is the perfect place to start. This public square is one of the most curiosity-inducing places to visit in Larissa. Next, head to Centaurs' Path, an increasingly popular hiking area, known for its eye-catching features.

In between the sights, don’t hesitate to take small detours to explore local stores and eateries. When you’re ready to continue your adventure, head to Saint Konstantinos Park. This mesmerizing park is a highly recommended experience. Nearby, you'll also find Paralia Voloy. Visit these for an interesting touch to your journey.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Thessaloniki. Thessaloniki offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

As dinnertime approaches, it's time to head out for a bite to eat in Thessaloniki. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Treat yourself to a delightful dinner at Mamalouka, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Clochard? It's another excellent option with a diverse menu. Consider reserving a table at Sofi's House Restaurant as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Thessaloniki.

After savoring a delicious meal, step into the vibrant nightlife at Castra- All Day Terrace Bar, where the evening is just getting started. In the same way, Barbaben - Bar/ba/ben offers a unique charm perfect for experiencing the local bar scene in Thessaloniki. Apallou is another top-recommended bar that is sure to get you into the mood for some dancing and celebrating.

Raise your glass and celebrate another amazing day of your road trip in Greece!

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Day 7

Day 7

  • Thessaloniki - Departure day
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  • Arch of Galerius
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Day 7 of your road trip in Greece is your departure day. This is your chance to catch a last glimpse of Thessaloniki before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, we recommend visiting Arch Of Galerius And Rotunda, a symbolic monument before you head out.

As your final day in Greece unfolds, enjoy a last-minute shopping spree in Thessaloniki's best shopping area, Modiano Market. Enjoy finding the perfect gift or keepsake to remind you of your wonderful trip to Greece.

Before you conclude your road trip in Greece, drop by another restaurant for a last chance at a memorable dining experience in Thessaloniki.

If you're in the mood to try something new, consider O Loytros, another top spot with a mouthwatering menu.

You’ll then say farewell to Thessaloniki. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Greece!

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