10-Day the Czech Republic Self-Drive Road Trip With Itinerary from Prague to Ceske Budejovice, Plzeň, and Ústí Nad Labem and surrounding area

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Escape the ordinary with this exciting 10-day road trip through the Czech Republic. Explore the diverse landscapes, lively cities, and beyond. Pack your bags, hit the road, and prepare for an unforgettable journey!

This perfectly planned road trip itinerary in the Czech Republic takes you through some of the best places to see in the country. You will spend 5 nights in Prague, 1 night in Ceske Budejovice, 2 nights in Plzeň, and 1 night in Ústí Nad Labem. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in the Czech Republic. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have got you covered.

Upon arriving in Prague, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover the Czech Republic on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in the Czech Republic. Prague Castle and Charles Bridge are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Old Town Square, learn more about the unique St. Vitus Cathedral, and immerse yourself in the vibrant atmosphere of Prague Astronomical Clock.

As you hit the open road and drive through Prague, Průhonice, Český Krumlov, Ceske Budejovice, Hluboká nad Vltavou, Blatná, Plzeň, Loket, Carlsbad, Ústí Nad Labem, Děčín, Mezná, Růžová, and Labská Stráň, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of the Czech Republic. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in the Czech Republic.

Throughout your road trip in the Czech Republic, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in the Czech Republic.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodation, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in the Czech Republic fill up quickly, so book your spot early. Select a date and start planning your road trip in the Czech Republic today!

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Driver’s age is 30 - 65
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Itinerary summary

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Days
Destination
Attractions
Overnight
Day
City & Overnight
Attractions
Charles Bridge
Old Town SquarePrague Astronomical ClockLennon WallSt. Vitus CathedralPrague Castle
VyšehradLetná ParkKrálovská obora StromovkaPrague ZooNature Park Draháň-Troja
Dancing HouseNational TheatreFranz Kafka - Rotating HeadPowder TowerNational Museum in Prague
Park PrůhoniceThe Castle GardenState Castle and Chateau Český Krumlov
Samson fountainBlack TowerThe State Chateau of HlubokáOhrada ZooCastle Blatná

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Day 1

Day 1

  • Prague - Arrival day
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  • Charles Bridge
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Your road trip adventure in the Czech Republic begins as soon as you reach Prague and pick up your car. You’ll stay in Prague for 4 nights and explore the best things to see and do, sample the local cuisine, and choose from a curated selection of the best hotels and places to stay in the city.

Prague is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Charles Bridge, or just taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

Find your way to your hotel in Prague. We recommend choosing a hotel in a central location for easy exploring. Check-in typically starts between 2 and 4 PM at hotels in the Czech Republic. Settle in and make plans for the evening.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Prague, it's often a good idea to reserve a table in advance.

Make sure to reserve a table at U Tellerů, an iconic dining spot in Prague. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Restaurace U Bansethů, a popular restaurant in Prague. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Eska Restaurant and Bakery, a hidden gem nestled in Prague. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Continue your lively evening at Anonymous Shrink's Office, a perfect place for winding down or revving up the night, depending on which mood you’re in. Bar No. 7 - Prague is another excellent bar that offers a great selection of drinks to suit any mood. If you prefer to go somewhere else, Kontakt Bar ensures a night out tailored to your taste.

Raise a toast to the start of your 10-day road trip in the Czech Republic!

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Day 2

Day 2

  • Prague
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Drive 5 km, 49 min

  • Old Town Square
  • Prague Astronomical Clock
  • Lennon Wall
  • St. Vitus Cathedral
  • Prague Castle
  • More

Day 2 of your road trip across the Czech Republic promises a magnificent time exploring Prague. You have 3 nights left in Prague. Take the opportunity to experience more of the best attractions and activities in the city.

Whether you prefer a leisurely exploration or a more fast-paced adventure, this itinerary in Prague allows for both. Start by heading to Old Town Square. This timeless public square provides an insightful glimpse into the city's identity. Next, discover Prague Astronomical Clock, a history-steeped historical landmark, promising a delightful encounter.

Continue your sightseeing with a visit to Lennon Wall, a notable street art. When you’re done, don’t forget to make a stop at the famous St. Vitus Cathedral. Round off your day at Prague Castle, another gem in Prague with UNESCO world heritage-designated features to discover.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. The Czech Republic is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Prague. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Make sure to reserve a table at Brasileiro Restaurant, an iconic dining spot in Prague. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Restaurant Meat Beer, a popular restaurant in Prague. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Restaurace Století, a hidden gem nestled in Prague. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Continue your evening by exploring the vibrant nightlife scene at Bowla Bar, a prime destination for a thrilling night out. Also, don’t forget to check out The Saints, a bar that offers unique local touches. Likewise, Beergeek Bar provides an excellent alternative for a fun evening.

Take some time to reflect on your day and savor another beautiful night in the Czech Republic.

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Day 3

Day 3

  • Prague
  • More

Drive 34 km, 1 hour 35 min

  • Vyšehrad
  • Letná Park
  • Královská obora Stromovka
  • Prague Zoo
  • Nature Park Draháň-Troja
  • More

Day 3 offers a multitude of experiences. You will stay in Prague for 2 nights more, offering you enough time to explore at a relaxed pace.

Prague is brimming with adventures. Today’s wonderful stops include a castle, a park, a zoo, a nature reserve and much more! Begin your sightseeing adventure at the well-known Vyšehrad and allow yourself time to explore. Just a short distance away you'll find your next stop, Letná Park, a serene park that draws visitors from far and near.

Continue your journey to Stromovka, one of the city’s most locally renowned spots that you shouldn’t miss. Another great site to visit is the top-rated Prague Zoo. When you're finished at the zoo, Nature Park Draháň-troja awaits your visit. This nature reserve is a romantic highlight on today's itinerary.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. The Czech Republic is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

As you explore more of Prague, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Dine in style at BeBop Bar, a top recommendation for dinner tonight. Or, for a change of pace, Café restaurant Palanda boasts a menu that's sure to impress. Also, be sure to check out Restaurace Tiskárna. Known as a local hotspot, it’s a great choice for tonight in Prague.

Let the evening flow smoothly from dinner to drinks at Uhříněveský Bar, a top-rated bar in the area. For other recommendations, Boothill Bar provides a perfect setting for rounding out your night with style and great drinks. Likewise, Manesova Bar And Books offers a memorable night with diverse drink options and excellent service.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in in the Czech Republic.

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Day 4

Day 4

  • Prague
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Drive 10 km, 1 hour 6 min

  • Dancing House
  • National Theatre
  • Franz Kafka - Rotating Head
  • Powder Tower
  • National Museum in Prague
  • More

Day 4 of your road trip will take you to the best attractions Prague has to offer. Cherish the 1 night you have left in Prague by discovering the best things there are to see and do in the city.

Today's adventure in Prague promises more breathtaking discoveries and enriching experiences! Begin at Dancing House. This respected art installation is a highlight of any visit in the city. Then, enjoy National Theatre, another romantic attraction that never fails to captivate visitors. Next, head over to Franz Kafka - Rotating Head By David Cerny, one of the city’s most popular attractions, known for its remarkable features.

If you’re looking for more, spend time soaking in the atmosphere of Powder Tower. This picture-perfect monument is frequented by locals and tourists alike. To complete your memorable day, make sure to visit Národní Muzeum (national Museum, Prague), a notable museum, and take a stroll around the area.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. The Czech Republic is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

Visit Wenceslas Square in Prague for an unforgettable shopping experience. Browse unique and stores, each offering delightful surprises. Find unique souvenirs or items to take home. After shopping, explore what Wenceslas Square has to offer, including attractions, essential services, and vibrant community activities.

Indulge in a memorable dining experience at one of Prague's most popular restaurants, and connect with friendly locals for an authentic adventure.

Savor the flavors at OSSEGG Praha - Pivovar & Restaurace, a top pick for dinner tonight. Alternatively, U Fleků beckons with its unique menu offerings. Also, consider Havelská Koruna. With its consistent customer satisfaction, it’s an excellent option for dining in Prague tonight.

After your delicious meal, get a taste of the vibrant nightlife with a visit to Bar Bohužel, known for its inviting atmosphere. Hemingway Bar is another great option if you’re looking for a place to get the night started. Similarly, Bar Tečka provides a great setting to enjoy the night away.

Head back to your accommodation in Prague and get some rest in preparation for another magical day of your road trip in the Czech Republic!

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Day 5

Day 5

  • Prague
  • České Budějovice
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Drive 207 km, 3 hours 7 min

  • Park Průhonice
  • The Castle Garden
  • State Castle and Chateau Český Krumlov
  • More

Embark on another extraordinary experience on day 5 of your road trip in the Czech Republic. Today, you will make 2 stops and experience some of the highlights of Průhonice and Český Krumlov. At the end of the day, you will enjoy the comforts of a top-rated hotel in Ceske Budejovice, which will be your home away from home for 1 night.

Today’s route brings fun adventures, romantic experiences, and natural wonders. The first attraction of today is Park Průhonice. This often recommended botanical garden is a mesmerizing place to see in Prague. Continue your discovery at The Castle Garden, a respected castle with stories to tell.

As you stroll around Prague, take in the distinct atmosphere and learn what makes this village so unique. Maximize your sightseeing with a visit to Český Krumlov Castle. This notable castle offers a history-steeped encounter with Prague. Whether you decide to get entrance tickets for all attractions or you prefer admiring from a distance, amazing experiences await on this day in Prague.

When you’re done exploring for the day, you’ll drive to your hotel in Ceske Budejovice. Check in and spend some time relaxing before you head out to tour the city.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Ceske Budejovice. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Treat yourself to a delightful dinner at Potrefená husa IGY, České Budějovice, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Paluba? It's another excellent option with a diverse menu. Consider reserving a table at Alchymista as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Ceske Budejovice.

If you’re not ready to end the night just yet, The Dark offers a perfect venue to relax and savor a drink. Similarly, Cafe Hostel is well-suited for those looking to unwind in a social setting. Singer Pub is another excellent spot to enjoy a nightcap after a delightful meal.

As the sun sets on another day of adventure, rest up and recharge for the next leg of your road trip in the Czech Republic.

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Day 6

Day 6

  • České Budějovice
  • Plzeň-City District
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Drive 147 km, 2 hours 25 min

  • Samson fountain
  • Black Tower
  • The State Chateau of Hluboká
  • Ohrada Zoo
  • Castle Blatná
  • More

On day 6 of your exciting self-drive vacation in the Czech Republic, you’ll soak in the magnificence of 3 destinations, Ceske Budejovice, Hluboká nad Vltavou, and Blatná. When you’re not sightseeing, take time to relax at your selected hotel in Plzeň, where you’ll be staying for 2 nights.

Immerse yourself in Ceske Budejovice’s rich culture with today's sightseeing itinerary. Start your journey at Samson Fountain. This culturally significant monument is sure to ignite your curiosity. Next, dive into the historic features of Black Tower, a must-visit monument in the city.

In between sights, stop by local stores, picturesque photo spots, and small eateries. When you’re ready for your next attraction, proceed to The State Chateau Of Hluboká, a captivating castle. For a change of scene, check out Ohrada Zoo, known for its breathtaking features. We also recommend visiting Castle Blatná. This castle is a must for anyone looking to experience the city to the fullest.

At the end of the day, you will drive to Plzeň, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

Indulge in a memorable dining experience at one of Plzeň's most popular restaurants, and connect with friendly locals for an authentic adventure.

Treat yourself to a wonderful meal at Raven Pub City, a top-rated dining spot in Plzeň. If you're in the mood for something new, try Restaurace & Hotel U Salzmannů, another premier location with a delectable menu. You might also want to book a table at Pláž OSTENDE BOLEVÁK. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Plzeň.

Let the evening flow smoothly from dinner to drinks at Francis - Beer Café, a top-rated bar in the area. For other recommendations, My Friends Bar provides a perfect setting for rounding out your night with style and great drinks. Likewise, Beer Bar Pioneer offers a memorable night with diverse drink options and excellent service.

Take some time to reflect on your day and savor another beautiful night in the Czech Republic.

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Day 7

Day 7

  • Plzeň-City District
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Drive 8 km, 44 min

  • Plzeň Zoo
  • Cathedral of St. Bartholomew
  • Náměstí Republiky, Plzeň
  • Pilsner Urquell Brewery
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On day 7 of your road trip, you will have an entire day to explore Plzeň. You’ll stay in Plzeň for 1 night and discover all the best things to see and do in the area.

A blend of fun adventures, scenic views, and photo-friendly spots await you in Plzeň on today’s itinerary. First up is the locally renowned zoo, Dinopark Plzeň. Afterward, continue to Cathedral Of St. Bartholomew, a church every traveler should visit.

As you explore Plzeň’s charming streets, take in the lively atmosphere and get to know the character of the city. Next, make your way to Náměstí Republiky, Plzeň. This increasingly popular public square is an essential stop. Following that, head to Pilsner Urquell Brewery, another must-visit site that will enhance your experience.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. The Czech Republic is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

As dinnertime approaches, it's time to head out for a bite to eat in Plzeň. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Don’t miss out on dining at Mely Restaurant, a top-rated dining destination in Plzeň. If you're in the mood to try something new, consider Parkan, another top spot with a mouthwatering menu. You might also want to secure a reservation at Restaurace U Lízalky. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Plzeň this evening.

After enjoying a delightful dinner, why not delve into the vibrant local bar scene? You might want to spend the evening at Cafe La Rose, Ltd. , a well-loved spot among locals and tourists. Or, head to Forest Bar. This bar boasts a welcoming environment that is perfect for winding down. You could also continue your night at Vinyl Coffee & Pub, another top-rated place in the area.

Raise your glass to another unforgettable day in the Czech Republic!

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Day 8

Day 8

  • Plzeň-City District
  • Ústí nad Labem
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Drive 217 km, 4 hours 9 min

  • Loket Castle
  • Vřídelní kolonáda
  • Mill Colonnade
  • Diana Observation Tower
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Experience an unparalleled adventure on day 8 of your road trip in the Czech Republic. This exciting part of your journey invites you to discover the renowned landmarks in 2 vibrant destinations - Loket and Carlsbad. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Ústí Nad Labem. You will spend 1 night here for some well-deserved relaxation.

Today’s itinerary in Plzeň covers several incredible sights, including a castle, a hot spring, a monument, an observation deck and much more! Start your adventure at Loket Castle. This notable castle is a place that is appreciated by travelers and locals alike. Next, immerse yourself in the enchanting wonders of Vřídelní Kolonáda, a must-see hot spring in the town.

Consider stopping for a small bite to eat or a drink at a local eatery to keep your energy going. When you’re ready, continue your discovery with a visit to Mill Colonnade. This interesting monument offers an enriching experience. For a change of pace, head to Rozhledna Diana, where you can take in visually striking features. These sights offer a fulfilling end to a perfect day.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Ústí Nad Labem. Ústí Nad Labem offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

As dinnertime approaches, it's time to head out for a bite to eat in Ústí Nad Labem. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Dine in style at Restaurant Větruše, a top recommendation for dinner tonight. Or, for a change of pace, Hotel a Restaurant Větruše boasts a menu that's sure to impress. Also, be sure to check out BLACKSHEEP BAR. Known as a local hotspot, it’s a great choice for tonight in Ústí Nad Labem.

Keep the excitement of the evening going by visiting a bar or two. Hp Bar is an excellent place to start. You could also check out Ústecká Pivotéka, offering a different kind of charm. A last recommendation for the day is Pubs Bar Hamburg. This bar promises an enjoyable experience with tasty drinks and a vibrant setting.

Say good night to Ústí Nad Labem and look forward to another great day of your road trip in the Czech Republic!

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Day 9

Day 9

  • Ústí nad Labem
  • Prague
  • More

Drive 199 km, 3 hours 16 min

  • Děčín Zoo
  • Kamenice Gorge
  • Bohemian Switzerland National Park
  • Mýdlárna Rubens
  • Labské pískovce Protected Landscape Area
  • More

On day 9 of your road trip in the Czech Republic, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Děčín, Mezná, Růžová, and Labská Stráň. In the evening, you’ll end up in Prague, where you will stay for 1 night.

Brace yourself for today’s incredible lineup of attractions in Ústí Nad Labem, featuring fun adventures, scenic views, and photo-friendly spots. Start at Děčín Zoo, an underrated zoo in the town. Then, head to Kamenice Gorge and soak in the ambiance of this romantic canyon.

There are many interesting places to see in Ústí Nad Labem, and when you are ready for more, go to České Švýcarsko National Park. This is one of the town’s most captivating instagrammable spots of interest. After exploring the national park, visit the intriguing Mýdlárna Rubens. Not far away, you'll also find Protected Landscape Area Elbe Sandstone Mountains. This nature reserve is a serene highlight in Ústí Nad Labem.

When you’re done exploring for the day, you’ll drive to your hotel in Prague. Check in and spend some time relaxing before you head out to tour the city.

After a day of adventure, treat yourself to an exquisite dinner at one of Prague's best restaurants.

Treat yourself to a delicious dinner at MAURIZIO restaurant & café, an excellent option for tonight's dining. Looking for something different? Gate Restaurant offers a tantalizing alternative with its diverse menu. And don’t miss U Houmra. With its reputation for pleasing customers, it’s a fantastic choice for tonight in Prague.

After enjoying a fulfilling meal, continue your evening at Crazy Daisy, ideal for those looking to unwind with a drink in a comfortable setting. Alternatively, Puerto Rico Cafe & Cocktail Bar offers a welcoming atmosphere for easing into the nightlife. Similarly, Anonymous Bar provides an excellent environment for a relaxed and enjoyable evening.

Savor another day of unforgettable experiences in the Czech Republic!

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Day 10

Day 10

  • Prague - Departure day
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  • Clementinum
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Day 10 of your road trip in the Czech Republic is your departure day. This is your chance to catch a last glimpse of Prague before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, we recommend visiting Clementinum, an awe-inspiring library before you head out.

As your final day in the Czech Republic unfolds, enjoy a last-minute shopping spree in Prague's best shopping area, Palladium. Enjoy finding the perfect gift or keepsake to remind you of your wonderful trip to the Czech Republic.

Before you conclude your road trip in the Czech Republic, drop by another restaurant for a last chance at a memorable dining experience in Prague.

Savor the flavors at Restaurace U Jindřišské věže, a top pick for dinner tonight. Alternatively, The Grand Mark Prague beckons with its unique menu offerings.

You’ll then say farewell to Prague. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in the Czech Republic!

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